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Protective effect of low dose of ascorbic acid on hepatobiliary function in hepatic ischemia/reperfusion in rats
Abstract
Background/aims The aim of this study was to investigate the effect of ascorbic acid (AA) an alterations in hepatic secretory and microsomal functions during hepatic ischemia and reperfusion.Methods Rats were subjected to 60 min of hepatic ischemia, and 1 and 5 h of reperfusion. Five minutes prior to ischemia, the animals were administered either vehicle or ascorbic acid (AA) (30, 100, 300, and 1000 mg/kg) intravenously.Results The serum aminotransferase level and lipid peroxidation were markedly higher as a result of ischemia/reperfusion. These increases were significantly attenuated by AA doses of 30 and 100 mg/kg but were augmented by dose of 1000 mg/kg. Bile flow and cholate output were markedly decreased by ischemia/reperfusion. AA doses of 30 and 100 mg/kg restored but dose of 1000 mg/kg inhibited their secretion. Both the cytochrome P(450) content and aminopyrine N-demethylase activity were decreased by ischemia/reperfusion, which were prevented by AA doses of 30 and 100 mg/kg but were aggravated by dose of 1000 mg/kg. Aniline p-hydroxylase activity was elevated by ischemia/reperfusion, and this was prevented by AA doses of 100, 300 and 1000 mg/kg.Conclusions Ischemia/reperfusion diminishes the hepatic secretory and microsomal functions. AA has both antioxidant and pro-oxidant effects, depending upon the dose.
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“Multiple studies showed no effect of vitamin C on markers of lipid peroxidation in healthy humans or animals [63,66,166].”
From Vitamin C-Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination (2021) · cites this paper as [166]
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Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
The Carbon Monoxide-binding Pigment of Liver Microsomes
Omura, T., & Sato, R. (1964) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)82244-3 · Cited by 11,781
Spectral Studies of Drug Interaction with Hepatic Microsomal Cytochrome
Schenkman, J. B., Remmer, H., & Estabrook, R. W. (1967) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)14748-2 · Cited by 1,195
Vitamin C exhibits pro-oxidant properties
Podmore, I. D., Griffiths, H. R., Herbert, K. E., Mistry, N., Mistry, P., & Lunec, J. (1998) · Nature · doi:10.1038/33308 · Cited by 800
Cellular functions of ascorbic acid
Padh, H. (1990) · Biochemistry and Cell Biology · doi:10.1139/o90-173 · Cited by 350
Studies of ascorbate-dependent, iron-catalyzed lipid peroxidation
Miller, D. M., & Aust, S. D. (1989) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(89)90261-0 · Cited by 264
Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats.
Bromont, C., Marie, C., & Bralet, J. (1989) · Stroke · doi:10.1161/01.str.20.7.918 · Cited by 233
INFLUENCE OF OXYGEN-DERIVED FREE RADICAL SCAVENGERS ON ISCHEMIC LIVERS
Atalla, S. L., Toledo-Pereyra, L. H., MacKenzie, G. H., & Cederna, J. P. (1985) · Transplantation · doi:10.1097/00007890-198512000-00002 · Cited by 221
Biological hydroxylation mechanisms
JEPSON, J. B. (1973) · Biochemical Education · doi:10.1016/0307-4412(73)90064-2 · Cited by 190
A PHOTOMETRIC METHOD FOR THE DETERMINATION OF CHOLATES IN BILE AND BLOOD
Irvin, J. L., Johnston, C. G., & Kopala, J. (1944) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71986-8 · Cited by 162
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Kim, S., Lee, B.-R., Reeder, J. T., Seo, S. H., Lee, S.-U., Hourlier‐Fargette, A., Shin, J., Sekine, Y., Jeong, H., Oh, Y. S., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2012700117 · Cited by 156
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Tada, M., Yokoyama, H., ITO, O., Ohya, H., & Ogata, T. (2003) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2004.03201.x · Cited by 27
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Azari, O., Kheirandish, R., Azizi, S., Abbasi, M. F., Chaman, S. G. G., & Bidi, M. (2015) · Europe PMC (PubMed Central) · Cited by 24
Astuti, R. I., Listyowati, S., & Wahyuni, W. T. (2019) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/299/1/012059 · Cited by 32
Khoei, N. S., Anton, G., Peters, A., Freisling, H., & Wagner, K. (2020) · Antioxidants · doi:10.3390/antiox9100908 · Cited by 25
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Abu‐Amara, M., Gurusamy, K. S., Hori, S., Glantzounis, G., Fuller, B. J., & Davidson, B. R. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007472.pub2 · Cited by 24
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Tata, V. D., Brizzi, S., Saviozzi, M., Lazzarotti, A., Fierabracci, V., Malvaldi, G., & Casini, A. (2004) · Journal of Surgical Research · doi:10.1016/j.jss.2004.08.008 · Cited by 24
Erkut, B., Ozyazicioglu, A. F., Karapolat, B. S., Koçoğulları, C. U., Keles, S., Ateç, A., Gündoğdu, C., & Koçak, H. (2007) · Drug Target Insights · doi:10.4137/dti.s303 · Cited by 23
Roosdiana, A., Permata, F. S., Fitriani, R. I., Umam, K., & Safitri, A. (2020) · Veterinary Medicine International · doi:10.1155/2020/8812758 · Cited by 23
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Wang, N. T., Lin, H. I., Yeh, D. Y.-W., Chou, T., Chen, C. F., Leu, F.-C., Wang, D., & Hu, R. T. (2009) · Transplantation Proceedings · doi:10.1016/j.transproceed.2009.08.051 · Cited by 20
Qi, M., Yao, Y., Xie, R., Sun, S., Sun, W., Wang, J., Chen, Y., Zhao, B., Chen, E., & Mao, E. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.04.111 · Cited by 18
Alam, M. M., Asiri, A. M., Rahman, M. M., & Islam, M. A. (2020) · SN Applied Sciences · doi:10.1007/s42452-020-03689-9 · Cited by 18
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Do natural antioxidants play a role in Alzheimer's disease?
Lange, K. W., Lange, K. M., Nakamura, Y., & Li, S. (2020) · Journal of Food Bioactives · doi:10.31665/jfb.2020.11233 · Cited by 17
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Ko, S. H., Jun, J. H., Oh, J. E., Shin, E., Kwak, Y. L., & Shim, J. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116407 · Cited by 16
Masuda, T., Iwashita, Y., Hagiwara, S., Ohta, M., Inomata, M., Noguchi, T., & Kitano, S. (2011) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.06773.x · Cited by 16
Current status of oxidative stress in pediatric liver transplantation
Czubkowski, P., Socha, P., & Pawłowska, J. (2010) · Pediatric Transplantation · doi:10.1111/j.1399-3046.2009.01256.x · Cited by 16
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Kuriyama, N., Isaji, S., Hamada, T., Kishiwada, M., Ohsawa, I., Usui, M., Sakurai, H., Tabata, M., Suzuki, K., & Üemoto, S. (2009) · Liver International · doi:10.1111/j.1478-3231.2008.01796.x · Cited by 16
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Lin, S., Liu, K., Wu, W.-K., Chen, C., Wang, Z., & Zhang, X. (2009) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x09006874 · Cited by 14
Huang, H., Yin, R., Zhu, J., Feng, X., Wang, C., Sheng, Y., Dong, G., Li, D., & Hua, J. (2007) · Journal of Surgical Research · doi:10.1016/j.jss.2006.12.553 · Cited by 13
Rajpoot, D. S., Prakash, A., Mandil, R., Rahal, A., & Garg, S. K. (2013) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2013.853005 · Cited by 12
Kazemi, M., Tabei, K., Najafizadeh, K., Sisakht, J. M., Milani, S., & Khosravi, M. B. (2015) · PubMed · Cited by 12
Stsiapura, V. I., Bederman, I. R., Stepuro, I. I., Morozkina, T. S., Lewis, S. J., Smith, L. A., Gaston, B. M., & Marozkina, N. V. (2018) · Pharmaceutical Biology · doi:10.1080/13880209.2017.1421674 · Cited by 12
Fu, Y., Chen, H., Zhou, J., Cheng, B.-R., & Zhang, J. (2013) · Pharmaceutical Biology · doi:10.3109/13880209.2013.802352 · Cited by 11
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Huang, H., Yin, R., Zhu, J., Feng, X., Wang, C., Sheng, Y., Dong, G., Li, D., & Hua, J. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.09.045 · Cited by 9
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Use of natural anti-oxidants in experimental animal models of hepatic ischemia-reperfusion injury
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Klyushova, L. S., Кандалинцева, Н. В., & Grishanova, A. Y. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44070216 · Cited by 7
Bratu, T., Rogobete, A. F., Săndesc, D., Bedreag, O. H., Tanasescu, S. A., Nitu, R., Popovici, S. E., & Crăiniceanu, Z. P. (2016) · Biochemical Genetics · doi:10.1007/s10528-016-9763-8 · Cited by 7
CHARACTERIZATION OF BLACK CUMIN SEED OIL AND EXPLORING ITS ROLE AS A FUNCTIONAL FOOD
Sultan, M. T. (2009) · HEC National Digital Library · Cited by 7
Mao, W., Liu, X., Fan, S., Zhang, R., Liu, M., & Xiao, S. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1549658 · Cited by 8
Harnessing the anti and pro-oxidants potential of selenium
Nath, D., Biradar, S., Sow, S., Suman, S. N., Kumar, V., Ranjan, S., Singh, S. K., Singh, H., Laik, R., Ghosh, M., et al. (2026) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2026.127827 · Cited by 6
Erkut, B., Ozyazicioglu, A. F., Karapolat, B. S., Koçoğulları, C. U., Keles, S., Ateş, A., Gündoğdu, C., & Koçak, H. (2007) · Drug Target Insights · doi:10.33393/dti.2007.1321 · Cited by 5
[Experimental models on hemorragic shock].
Mauriz, J. L., Renedo, J. M., Lera, J. P. B., Culebras, J. M., & González, P. (2007) · PubMed · Cited by 5
Role of Antioxidants Supplementation in the Treatment of Male Infertility
Amor, H., Shelko, N., Mohammed, M., Jankowski, P. M., & Hammadeh, M. E. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.95891 · Cited by 5
Antioxidant Vitamins and Adrenocorticotrophic Hormone-Induced Hypertension in Rats
Schyvens, C. G., Andrews, M. C., Tam, R., Mori, T. A., Croft, K. D., McKenzie, K. U. S., Whitworth, J. A., & Zhang, Y. (2007) · Clinical and Experimental Hypertension · doi:10.1080/10641960701615774 · Cited by 5
Does vitamin C minimise exercise-induced oxidative stress?
Sukri, N. M. (2021) · Sport Sciences for Health · doi:10.1007/s11332-021-00756-5 · Cited by 6
Harnessing the fundamental roles of vitamins: the potent anti-oxidants in longevity
Izadi, M., Sadri, N., Abdi, A., Zadeh, M. M. R., Sadatipour, S., Baghdadi, G., Jalaei, D., & Tahmasebi, S. (2025) · Biogerontology · doi:10.1007/s10522-025-10202-5 · Cited by 4
Libik‐Konieczny, M., Kozieradzka-Kiszkurno, M., Michalec-Warzecha, Ż., Miszalski, Z., Bizan, J., & Konieczny, R. (2017) · Acta Physiologiae Plantarum · doi:10.1007/s11738-017-2466-x · Cited by 4
Phytochemicals as Pro-oxidants in Cancer
Mahanta, S. K., & Challa, S. R. (2022) · Handbook of Oxidative Stress in Cancer: Therapeutic Aspects · doi:10.1007/978-981-16-1247-3_209-1 · Cited by 4
Metadata
- Authors
- Seo, M.-Y., & Lee, S.-M.
- Affiliations
- Sungkyunkwan University (KR)
- Corresponding author
- Lee, Sun-Mee
- Venue
- Journal of Hepatology
- Publisher
- Elsevier BV
- Published
- 2002-01
- Volume
- 36
- Issue
- 1
- Pages
- 72-77
- ISSN
- 0168-8278 (ISSN-L)
- OpenAlex
- W2043649744
- Cited by
- 131
- References
- 29
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 5 · 2023: 3 · 2022: 7 · 2021: 12 · 2020: 11 · 2019: 7 · 2018: 5 · 2017: 1 · 2016: 3 · 2015: 5 · 2014: 4 · 2013: 4 · 2012: 5
- FWCI
- 3.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Hepatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Organ Transplantation Techniques and Outcomes
- Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Drug-Induced Hepatotoxicity and Protection
- Keywords
- vitamin C, hepatic ischemia-reperfusion, hepatoprotection, hepatobiliary function, bile flow, lipid peroxidation, transaminases, cytochrome P450, aminopyrine N-demethylase, dose-dependent effects, liver microsomal enzymes
- MeSH terms
- Alanine Transaminase, Aminopyrine N-Demethylase, Animals, Antioxidants, Ascorbic Acid, Bile, Cytochrome P-450 Enzyme System, Liver, Male, Microsomes, Liver, Lipid Peroxidation, Reperfusion Injury, Rats, Sprague-Dawley, Rats
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