Cited by 389Histone Deacetylase Inhibitors ResearchGenomics and Chromatin DynamicsEpigenetics and DNA Methylation

The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.

NuRD and SIN3

Ahringer, Julie·2000·Trends in Genetics

DOI 10.1016/s0168-9525(00)02066-7

Open this paper in CoChat — free account

Abstract

Transcription repression mediated through histone deacetylase (HDAC) complexes is widespread, and mechanisms by which HDAC complexes act have been revealed by extensive studies in vitro and in cell culture. However, until recently, little has been known about the developmental roles of histone deacetylation. Mutants now exist for a number of members of the two major HDAC complexes (NuRD and SIN3) and some associated proteins. The emerging picture is that these complexes have specific functions in development, rather than being required for most cellular processes.

Integrity signals

Registry

Crossref · 10.1016/s0168-9525(00)02066-7

Cites

63 of 63 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
Amir, R. E., Van den Veyver, I. B., Wan, M., Tran, C. Q., Francke, U., & Zoghbi, H. Y. (1999) · Nature Genetics · doi:10.1038/13810 · Cited by 4,990
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
Jones, P. L., Veenstra, G. J. C., Wade, P. A., Vermaak, D., Kass, S. U., Landsberger, N., Strouboulis, J., & Wolffe, A. P. (1998) · Nature Genetics · doi:10.1038/561 · Cited by 2,791
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
Hörlein, A., Näär, A. M., Heinzel, T., Torchia, J., Gloss, B. R., Kurokawa, R., Ryan, A. K., Kamei, Y., Söderström, M., Glass, C. K., et al. (1995) · Nature · doi:10.1038/377397a0 · Cited by 2,072
A transcriptional co-repressor that interacts with nuclear hormone receptors
Chen, J. D., & Evans, R. M. (1995) · Nature · doi:10.1038/377454a0 · Cited by 1,794
Retinoblastoma protein recruits histone deacetylase to repress transcription
Brehm, A., Miska, E. A., McCance, D. J., Reid, J. L., Bannister, A. J., & Kouzarides, T. (1998) · Nature · doi:10.1038/35404 · Cited by 1,231
Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase
Nagy, L., Kao, H.-Y., Chakravarti, D., Lin, R. J., Hassig, C. A., Ayer, D. E., Schreiber, S. L., & Evans, R. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80218-4 · Cited by 1,230
A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression
Heinzel, T., Lavinsky, R. M., Mullen, T.-M., Söderström, M., Laherty, C. D., Torchia, J., Yang, W., Brard, G., Ngo, S. D., Davie, J., et al. (1997) · Nature · doi:10.1038/387043a0 · Cited by 1,210
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
Zhang, Y., Ng, H.-H., Erdjument-Bromage, H., Tempst, P., Bird, A., & Reinberg, D. (1999) · Genes & Development · doi:10.1101/gad.13.15.1924 · Cited by 1,103
Role of the histone deacetylase complex in acute promyelocytic leukaemia
Lin, R. J., Nagy, L., Inoue, S., Shao, W., Miller, W. H., & Evans, R. M. (1998) · Nature · doi:10.1038/35895 · Cited by 1,060

Show all 63 references

Sorted by citations

Items 101–200 of 389

Transcription Regulation of Abiotic Stress Responses in Rice: A Combined Action of Transcription Factors and Epigenetic Mechanisms
Santos, A. P., Serra, T. S., Figueiredo, D. D., Barros, P. M., Lourenço, T. F., Chander, S., Oliveira, M. M., & Saibo, N. J. M. (2011) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2011.0095 · Cited by 98
CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now
O’Shaughnessy, A., & Hendrich, B. (2013) · Biochemical Society Transactions · doi:10.1042/bst20130027 · Cited by 97
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma
Lodrini, M., Oehme, I., Schroeder, C., Milde, T., Schier, M. C., Kopp‐Schneider, A., Schulte, J. H., Fischer, M., Preter, K. D., Pattyn, F., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt346 · Cited by 96
Role of Histone-Modifying Enzymes and Their Complexes in Regulation of Chromatin Biology
DesJarlais, R. L., & Tummino, P. J. (2016) · Biochemistry · doi:10.1021/acs.biochem.5b01210 · Cited by 100
Role for the Mortality Factors MORF4, MRGX, and MRG15 in Transcriptional Repression via Associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split
Yochum, G. S., & Ayer, D. E. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.22.7868-7876.2002 · Cited by 95
MLL: How complex does it get?
Popovic, R., & Zeleznik‐Le, N. J. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20430 · Cited by 94
C. elegans Class B Synthetic Multivulva Genes Act in G 1 Regulation
Boxem, M., & van den Heuvel, S. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00844-8 · Cited by 92
Identification of the Sin3-Binding Site in Ume6 Defines a Two-Step Process for Conversion of Ume6 from a Transcriptional Repressor to an Activator in Yeast
Washburn, B. K., & Esposito, R. E. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.6.2057-2069.2001 · Cited by 91
The epigenetic pathways to ribosomal DNA silencing
Srivastava, R., Srivastava, R., & Ahn, S. H. (2016) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00005-16 · Cited by 90
Requirement of histone deacetylase1 (HDAC1) in signal transducer and activator of transcription 3 (STAT3) nucleocytoplasmic distribution
Ray, S., Lee, C., Hou, T., Boldogh, I. R., & Brasier, A. R. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn419 · Cited by 105
Conversion of a gene-specific repressor to a regional silencerPreprint
Rusché, L. N. (2001) · Genes & Development · doi:10.1101/gad.873601 · Cited by 89
Pf1, a Novel PHD Zinc Finger Protein That Links the TLE Corepressor to the mSin3A-Histone Deacetylase Complex
Yochum, G. S., & Ayer, D. E. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.13.4110-4118.2001 · Cited by 88
Why do genes have introns? Recombination might add a new piece to the puzzle
Duret, L. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(01)02236-3 · Cited by 88
The SIN3 Deacetylase Complex Represses Genes Encoding Mitochondrial Proteins
Pile, L. A., Spellman, P. T., Katzenberger, R. J., & Wassarman, D. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305996200 · Cited by 85
Photoperiodic Regulation of Flowering Time through Periodic Histone Deacetylation of the Florigen Gene FT
Gu, X., Wang, Y., & He, Y. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001649 · Cited by 86
The NuRD Complex: Linking Histone Modification to Nucleosome Remodeling
Feng, Q. F., & Zhang, Y. (2003) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-55747-7_10 · Cited by 85
Effects of Histone Deacetylase Inhibitors on HIF-1
Liang, D., Kong, X., & Sang, N. (2006) · Cell Cycle · doi:10.4161/cc.5.21.3409 · Cited by 85
Physical and Functional Interactions between the Histone H3K4 Demethylase KDM5A and the Nucleosome Remodeling and Deacetylase (NuRD) Complex
Nishibuchi, G., Shibata, Y., Hayakawa, T., Hayakawa, N., Ohtani, Y., Shinmyozu, K., Tagami, H., & Nakayama, J. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.573725 · Cited by 85
Insight into the Architecture of the NuRD Complex
Alqarni, S. S. M., Murthy, A., Zhang, W., Przewloka, M. R., Silva, A. P. G., Watson, A. A., Lejon, S., Pei, X. Y., Smits, A. H., Kloet, S. L., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.558940 · Cited by 84
MOF-Regulated Acetylation of MSL-3 in the Drosophila Dosage Compensation Complex
Buscaino, A., Köcher, T., Kind, J., Holz, H., Taipale, M., Wagner, K., Wilm, M. S., & Akhtar, A. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00140-0 · Cited by 84
A Drosophila Model of Multiple Endocrine Neoplasia Type 2
Read, R. D., Goodfellow, P. J., Mardis, E. R., Novak, N., Armstrong, J. R., & Cagan, R. L. (2005) · Genetics · doi:10.1534/genetics.104.038018 · Cited by 84
Epigenetics in C. elegans : Facts and challenges
Wenzel, D., Palladino, F., & Jedrusik, M. A. (2011) · genesis · doi:10.1002/dvg.20762 · Cited by 88
DNA methylation learns to fly
Lyko, F. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(01)02234-x · Cited by 82
colgate/hdac1 repression of foxd3 expression is required to permit mitfa-dependent melanogenesis
Ignatius, M. S., Moose, H. E., El‐Hodiri, H. M., & Henion, P. D. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.10.045 · Cited by 84
Murine Sall1 represses transcription by recruiting a histone deacetylase complex
Kiefer, S. M., McDill, B. W., Yang, J., & Rauchman, M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200052200 · Cited by 79
Epigenetics: New Questions on the Response to Hypoxia
Perez-Perri, J. I., Acevedo, J. M., & Wappner, P. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms12074705 · Cited by 82
Sumoylation of EKLF Promotes Transcriptional Repression and Is Involved in Inhibition of Megakaryopoiesis
Siatecka, M., Li, X., & Bieker, J. J. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00589-07 · Cited by 78
Functional Requirement for Histone Deacetylase 1 in Caenorhabditis elegans Gonadogenesis
Dufourcq, P., Victor, M., Gay, F., Calvo, D., Hodgkin, J., & Shi, Y. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.9.3024-3034.2002 · Cited by 75
Evolution of the arginase fold and functional diversity
Dowling, D., Costanzo, L. D., Gennadios, H. A., & Christianson, D. W. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-7554-z · Cited by 75
PICKLE is a CHD subfamily II ATP-dependent chromatin remodeling factor
Ho, K. K., Zhang, H., Golden, B. L., & Ogas, J. (2012) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2012.10.011 · Cited by 73
Ten members of the Arabidopsis gene family encoding methyl-CpG-binding domain proteins are transcriptionally active and at least one, AtMBD11, is crucial for normal development
Berg, A. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg735 · Cited by 74
RETRACTED: Methylglyoxal Modification of mSin3A Links Glycolysis to Angiopoietin-2 Transcription
Yao, D., Taguchi, T., Matsumura, T., Pestell, R. G., Edelstein, D., Giardino, I., Suske, G., Ahmed, N., Thornalley, P. J., Sarthy, V. P., et al. (2006) · Cell · doi:10.1016/j.cell.2005.11.024 · Cited by 73
Retracted
Histone Deacetylase Inhibitors: The Epigenetic Therapeutics That Repress Hypoxia‐Inducible Factors
Chen, S., & Sang, N. (2010) · BioMed Research International · doi:10.1155/2011/197946 · Cited by 73
Ikaros-CtIP Interactions Do Not Require C-terminal Binding Protein and Participate in a Deacetylase-independent Mode of Repression
Koipally, J., & Georgopoulos, K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202079200 · Cited by 72
Constraint of gene expression by chromatin remodelling protein CHD4 facilitates lineage specification
O’Shaughnessy-Kirwan, A., Signolet, J., Costello, I., Gharbi, S., & Hendrich, B. (2015) · Development · doi:10.1242/dev.125450 · Cited by 70
Chromatin Modification and the Endothelial-specific Activation of the E-selectin Gene
Edelstein, L. C., Pan, A., & Collins, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m412997200 · Cited by 71
Selective Recognition of H3.1K36 Dimethylation/H4K16 Acetylation Facilitates the Regulation of All-trans-retinoic Acid (ATRA)-responsive Genes by Putative Chromatin Reader ZMYND8
Adhikary, S., Sanyal, S., Basu, M., Sengupta, I., Sen, S., Srivastava, D. K., Roy, S., & Das, C. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.679985 · Cited by 71
Epigenetic developmental mechanisms in plants: molecules and targets of plant epigenetic regulation
Habu, Y., Kakutani, T., & Paszkowski, J. (2001) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00182-9 · Cited by 71
Dynamic Histone Acetylation of Late Embryonic Genes during Seed Germination
Tai, H. H., Tai, G. C. C., & Beardmore, T. (2005) · Plant Molecular Biology · doi:10.1007/s11103-005-2081-x · Cited by 75
HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations
Swanson, K. A., Knoepfler, P. S., Huang, K., Kang, R. S.-O., Cowley, S. M., Laherty, C. D., Eisenman, R. N., & Radhakrishnan, I. (2004) · Nature Structural & Molecular Biology · doi:10.1038/nsmb798 · Cited by 70
MeCP2 and other methyl‐cpg binding proteins
Jørgensen, H. F., & Bird, A. P. (2002) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.10021 · Cited by 71
Role of nucleosome remodeling in neurodevelopmental and intellectual disability disorders
López, A. J., & Wood, M. A. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00100 · Cited by 74
HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells
Peixoto, P., CASTRONOVO, V., Mathéus, N., Polese, C., Peulen, O., Gonzalez, A., Boxus, M., Verdin, E. M., Thiry, M., Dequiedt, F., et al. (2012) · Cell Death and Differentiation · doi:10.1038/cdd.2012.3 · Cited by 68
Engineering a Protein Scaffold from a PHD Finger
Kwan, A. H., Gell, D. A., Verger, A., Crossley, M., Matthews, J. M., & Mackay, J. P. (2003) · Structure · doi:10.1016/s0969-2126(03)00122-9 · Cited by 66
Host Cell-Dependent Expression of Latent Epstein–Barr Virus Genomes: Regulation by DNA Methylation
Li, H., & Minárovits, J. (2003) · Advances in cancer research · doi:10.1016/s0065-230x(03)01004-2 · Cited by 66
Histone modifications as key regulators of transcription
Asad, U. K. (2005) · Frontiers in bioscience · doi:10.2741/1580 · Cited by 67
Silencing of A γ-Globin Gene Expression during Adult Definitive Erythropoiesis Mediated by GATA-1-FOG-1-Mi2 Complex Binding at the −566 GATA Site
Harju-Baker, S., Costa, F. C., Fedosyuk, H., Neades, R. Y., & Peterson, K. R. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.01858-07 · Cited by 65
Recruitment of a SAP18-HDAC1 Complex into HIV-1 Virions and Its Requirement for Viral Replication
Sorin, M., Cano, J., Das, S., Mathew, S., Wu, X., Davies, K., Shi, X.-L., Cheng, S., Ott, D., & Kalpana, G. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000463 · Cited by 60
Long-range histone acetylation of the Ifng gene is an essential feature of T cell differentiation
Zhou, W., Chang, S., & Aune, T. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306002101 · Cited by 63
ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis
Li, R., Zhang, H., Yu, W., Chen, Y., Gui, B., Liang, J., Wang, Y., Sun, L., Yang, X., Zhang, Y., et al. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.211 · Cited by 63
Targeting of Krüppel-associated Box-containing Zinc Finger Proteins to Centromeric Heterochromatin
Matsuda, E., Agata, Y., Sugai, M., Katakai, T., Gonda, H., & Shimizu, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010663200 · Cited by 66
Acetylated, methylated, remodeled: chromatin states for gene regulation
Lusser, A. (2002) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(02)00287-x · Cited by 63
Unusual DNA Structures Associated With Germline Genetic Activity in Caenorhabditis elegans
Fire, A. Z., Alcazar, R., & Tan, F. J. (2006) · Genetics · doi:10.1534/genetics.106.057364 · Cited by 63
Autoregulation of Mouse Histone Deacetylase 1 Expression
Schuettengruber, B., Simboeck, E., Khier, H., & Seiser, C. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.19.6993-7004.2003 · Cited by 63
The Drosophila MBD2/3 protein mediates interactions between the MI-2 chromatin complex and CpT/A-methylated DNA
Marhold, J., Kramer, K., Kremmer, E., & Lyko, F. (2004) · Development · doi:10.1242/dev.01531 · Cited by 64
CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins
Tai, H. H., Geisterfer, M., Bell, J. C., Moniwa, M., Davie, J., Boucher, L., & McBurney, M. W. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)01354-8 · Cited by 61
Protein Expression Profile of the Mouse Metaphase-II Oocyte
Ma, M., Guo, X., Wang, F., Zhao, C. L., Liu, Z., Shi, Z., Wang, Y., Zhang, P., Zhang, K., Wang, N., et al. (2008) · Journal of Proteome Research · doi:10.1021/pr800392s · Cited by 60
C. elegans Rb, NuRD, and Ras regulate lin-39 -mediated cell fusion during vulval fate specification
Chen, Z., & Han, M. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00596-6 · Cited by 60
A Molecular Dissection of the Repression Circuitry of Ikaros
Koipally, J., & Georgopoulos, K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201694200 · Cited by 60
Epigenetic control of exercise training-induced cardiac hypertrophy by miR-208
Soci, Ú. P. R., Fernandes, T. M., Baraúna, V. G., Hashimoto, N. Y., da Mota, G. D. F. A., Rosa, K. T., Irigoyen, M. C., Phillips, M. I., & de Oliveira, E. M. (2016) · Clinical Science · doi:10.1042/cs20160480 · Cited by 59
Essential role of Drosophila Hdac1 in homeotic gene silencing
Chang, Y.-L., Peng, Y.-H., Pan, I.-C., Sun, D., King, B. O., & Huang, D.-H. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.171325498 · Cited by 59
Characterization of BHC80 in BRAF–HDAC complex, involved in neuron-specific gene repression
Iwase, S., Januma, A., Miyamoto, K., Shono, N., Honda, A., Yanagisawa, J., & Baba, T. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.07.163 · Cited by 57
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
Mallm, J., Iskar, M., Ishaque, N., Klett, L. C., Kugler, S. J., Muiño, J. M., Teif, V. B., Poos, A. M., Großmann, S., Erdel, F., et al. (2019) · Molecular Systems Biology · doi:10.15252/msb.20188339 · Cited by 57
Modulation of cell cycle regulators by HDACs
Seto, E. (2012) · Frontiers in Bioscience-Scholar · doi:10.2741/s303 · Cited by 56
Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor
Sahu, S. C., Swanson, K. A., Kang, R. S.-O., Huang, K., Brubaker, K., Ratcliff, K., & Radhakrishnan, I. (2007) · Journal of Molecular Biology · doi:10.1016/j.jmb.2007.11.079 · Cited by 56
Interplay between SIN3A and STAT3 Mediates Chromatin Conformational Changes and GFAP Expression during Cellular Differentiation
Cheng, P.-Y., Lin, Y., Chen, Y., Lee, Y., Tai, C.-C., Wang, Y.-T., Chen, Y., Kao, C.-F., & Yu, J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022018 · Cited by 59
Regulation of histone modifying enzymes by the ubiquitin–proteasome system
Zou, C., & Mallampalli, R. K. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2013.12.016 · Cited by 53
Sequence-specific transcriptional repression by an MBD2-interacting zinc finger protein MIZF
Sekimata, M. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh249 · Cited by 56
The leukaemia‐associated transcription factors EVI‐1 and MDS1/EVI1 repress transcription and interact with histone deacetylase
Vinatzer, U., Taplick, J., Seiser, C., Fonatsch, C., & Wieser, R. (2001) · British Journal of Haematology · doi:10.1046/j.1365-2141.2001.02987.x · Cited by 54
The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex
Knock, E., Pereira, J. D., Lombard, P., Dimond, A., Leaford, D., Livesey, F. J., & Hendrich, B. (2015) · Neural Development · doi:10.1186/s13064-015-0040-z · Cited by 55
Red meat intake-induced increases in fecal water genotoxicity correlate with pro-carcinogenic gene expression changes in the human colon
Hebels, D. G. A. J., Sveje, K. M., de Kok, M. C., van Herwijnen, M. H. M., Kuhnle, G., Engels, L. G. J. B., Vleugels-Simon, C. B. E. M., Mares, W. G. N., Pierik, M. J., Masclee, A., et al. (2011) · Food and Chemical Toxicology · doi:10.1016/j.fct.2011.10.038 · Cited by 55
PHA-4/FoxA cooperates with TAM-1/TRIM to regulate cell fate restriction in the C. elegans foregut
Kiefer, J. C., Smith, P. A., & Mango, S. E. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.11.042 · Cited by 48
Methyl-CpG–DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2
Patra, S. K., Patra, A., Zhao, H. L., Carroll, P. R., & Dahiya, R. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00253-5 · Cited by 52
Computational Studies on the Histone Deacetylases and the Design of Selective Histone Deacetylase Inhibitors
Wang, D. (2009) · Current Topics in Medicinal Chemistry · doi:10.2174/156802609788085287 · Cited by 51
Silencing Mediator of Retinoid and Thyroid Hormone Receptors and Activating Signal Cointegrator-2 as Transcriptional Coregulators of the Orphan Nuclear Receptor Nur77
Sohn, Y. C., Kwak, E., Na, Y., Lee, J. W., & Lee, S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107208200 · Cited by 50
Arabidopsis RPD3-like histone deacetylases form multiple complexes involved in stress response
Feng, C., Cai, X., Su, Y., Li, L., Chen, S., & He, X. (2021) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2021.04.004 · Cited by 49
Valproic acid-induced skeletal malformations: associated gene expression cascades
Massa, V., Cabrera, R. M., Menegola, E., Giavini, E., & Finnell, R. H. (2005) · Pharmacogenetics and Genomics · doi:10.1097/01.fpc.0000170914.11898.3a · Cited by 49
Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions
Law, R. D., & Suttle, J. C. (2005) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2005.03.014 · Cited by 51
Atrophin contributes to the negative regulation of epidermal growth factor receptor signaling in Drosophila
Charroux, B., Freeman, M., Kerridge, S., & Baonza, A. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2005.12.012 · Cited by 48
TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells
Vietor, I., Vadivelu, S. K., Wick, N., Hoffman, R. M., Cotten, M. L., Seiser, C., Fialka, I., Wunderlich, W., Haase, A. D. D., Kořínková, G., et al. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf461 · Cited by 48
Different Mi-2 Complexes for Various Developmental Functions in Caenorhabditis elegans
Passannante, M., Marti, C.-O., Pfefferli, C., Moroni, P. S., Kaeser-Pebernard, S., Puoti, A., Hunziker, P., Wicky, C., & Müller, F. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013681 · Cited by 47
The roles of twoC. elegansHOX co-factor orthologs in cell migration and vulva development
Yang, L. L., Sym, M., & Kenyon, C. J. (2005) · Development · doi:10.1242/dev.01569 · Cited by 47
Crosstalk between TGF-β signaling and epigenome
Bai, J., & Xi, Q. (2017) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmx122 · Cited by 52
The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation
Mugat, B., Nicot, S., Chavez, C. V., Jourdan, C., Sato, K., Basyuk, E. I., Juge, F., Siomi, M. C., Pélisson, A., & Chambeyron, S. (2020) · Nature Communications · doi:10.1038/s41467-020-16635-5 · Cited by 49
Global methylation screening in the Arabidopsis thaliana and Mus musculus genome: applications of virtual image restriction landmark genomic scanning (Vi-RLGS)
Matsuyama, T. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg488 · Cited by 47
Distinct Functional and Temporal Requirements for Zebrafish Hdac1 during Neural Crest-Derived Craniofacial and Peripheral Neuron Development
Ignatius, M. S., Eroglu, A. U., Malireddy, S., Gallagher, G. R., Nambiar, R. M., & Henion, P. D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063218 · Cited by 50
Whole-Exome Sequencing of Matched Primary and Metastatic Papillary Thyroid Cancer
Masoodi, T., Siraj, A. K., Siraj, S., Azam, S., Qadri, Z., Albalawy, W. N., Parvathareddy, S. K., Al-Sobhi, S. S., Al‐Dayel, F., Alkuraya, F. S., et al. (2019) · Thyroid · doi:10.1089/thy.2019.0052 · Cited by 47
Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis
Ma, L., Xie, D., Luo, M., Lin, X., Nie, H., Chen, J., Gao, C., Duo, S., & Han, C. (2022) · Science Advances · doi:10.1126/sciadv.abn1606 · Cited by 46
A Novel Germ Cell-specific Protein, SHIP1, Forms a Complex with Chromatin Remodeling Activity during Spermatogenesis
Choi, E., Han, C., Park, I., Lee, B., Jin, S., Choi, H., Kim, D. H., Park, Z., Eddy, E. M., & Cho, C. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m805590200 · Cited by 46
The stem-loop binding protein CDL-1 is required for chromosome condensation, progression of cell death and morphogenesis inCaenorhabditis elegans
Kodama, Y., Rothman, J. H., Sugimoto, A., & Yamamoto, M. P. (2002) · Development · doi:10.1242/dev.129.1.187 · Cited by 46
Role ofC. elegans lin-40MTA in vulval fate specification and morphogenesis
Chen, Z., & Han, M. (2001) · Development · doi:10.1242/dev.128.23.4911 · Cited by 46
Planarian MBD2/3 is required for adult stem cell pluripotency independently of DNA methylation
Jaber‐Hijazi, F., Lo, P. J. K. P., Mihaylova, Y., Foster, J. M., Benner, J. S., Romero, B. T., Chen, C., Malla, S., Solana, J., Ruzov, A. S., et al. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.09.020 · Cited by 45
The regulation of ATP-dependent nucleosome remodelling factors
Hogan, C., & Varga‐Weisz, P. (2007) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2006.07.010 · Cited by 46
Metabolic profiling of the Arabidopsis pkl mutant reveals selective derepression of embryonic traits
Rider, S. D., Hemm, M. R., Hostetler, H. A., Li, H., Chapple, C. C. S., & Ogas, J. (2004) · Planta · doi:10.1007/s00425-004-1254-1 · Cited by 45
Regulating the Regulators: The Role of Histone Deacetylase 1 (HDAC1) in Erythropoiesis
Kim, M. Y., Yan, B., Huang, S., & Qiu, Y. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228460 · Cited by 47
Senataxin controls meiotic silencing through ATR activation and chromatin remodeling
Yeo, A. J., Bécherel, O. J., Luff, J., Graham, M. E., Richard, D. J., & Lavin, M. F. (2015) · Cell Discovery · doi:10.1038/celldisc.2015.25 · Cited by 37
Regulation and function of small heat shock protein genes during amphibian development
Heikkila, J. J. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20237 · Cited by 43
The activity of theDrosophilamorphogenetic protein Bicoid is inhibited by a domain located outside its homeodomain
Zhao, C., York, A. J., Yang, F., Forsthoefel, D. J., Davé, V., Fu, D., Zhang, D., Corado, M., Small, S., Seeger, M. A., et al. (2002) · Development · doi:10.1242/dev.129.7.1669 · Cited by 43
Nuclear functions of endocytic proteins
Pilecka, I., Banach‐Orlowska, M., & Miączyńska, M. (2007) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2007.04.004 · Cited by 42
A Phosphomimetic Mutation in the Sall1 Repression Motif Disrupts Recruitment of the Nucleosome Remodeling and Deacetylase Complex and Repression of Gbx2
Lauberth, S. M., Bilyeu, A., Firulli, B. A., Kroll, K. L., & Rauchman, M. I. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m703702200 · Cited by 46

Authors: Ahringer, J.
Affiliations: Wellcome Trust (GB)
Corresponding author: Ahringer, Julie
ORCID: Ahringer, Julie
Venue: Trends in Genetics
Publisher: Elsevier BV
Published: 2000-08
Volume: 16
Issue: 8
Pages: 351-356
ISSN: 0168-9525 (ISSN-L)
DOI: 10.1016/s0168-9525(00)02066-7
OpenAlex: W2027297574
Cited by: 388
References: 63
Citations by year: 2026: 8 · 2025: 5 · 2024: 2 · 2023: 5 · 2022: 5 · 2021: 4 · 2020: 7 · 2019: 8 · 2018: 4 · 2017: 11 · 2016: 8 · 2015: 13 · 2014: 15 · 2013: 16 · 2012: 16
FWCI: 2.42
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Genetics (publishedVersion)
PubMed (publishedVersion)
Funders: Wellcome Trust (054523)
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Histone Deacetylase Inhibitors Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
Keywords: NuRD complex, histone deacetylase complex, transcriptional repression, histone deacetylation, developmental gene regulation, chromatin regulation
MeSH terms: Animals, Histone Deacetylases, Humans, Models, Biological, Receptors, Cell Surface, Transcription, Genetic, Arabidopsis, ras Proteins, Macromolecular Substances, Mi-2 Nucleosome Remodeling and Deacetylase Complex, Sin3 Histone Deacetylase and Corepressor Complex

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

NuRD and SIN3

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks