Nanoparticulate systems for brain delivery of drugs.

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

Cordon‐Cardo, C., O’Brien, J. P., Casals, D., Rittmann-Grauer, L., Biedler, J. L., Melamed, M. R., & Bertino, J. R. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.2.695 · Cited by 1,750

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

Pitas, R. E., Boyles, J. K., Lee, S. H., Foss, D., & Mahley, R. W. (1987) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(87)90295-5 · Cited by 693

Brain drug delivery of small molecules using immunoliposomes

Huwyler, J., Wu, D., & Pardridge, W. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.14164 · Cited by 660

An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In Vitro

Dehouck, M., Méresse, S., Delorme, P., Fruchart, J., & Cecchelli, R. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb01236.x · Cited by 548

Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)

Kreuter, J., Alyautdin, R. N., Kharkevich, D. A., & Aa, I. (1995) · Brain Research · doi:10.1016/0006-8993(95)00023-j · Cited by 538

Significant Transport of Doxorubicin into the Brain with Polysorbate 80-Coated Nanoparticles

Gulyaev, A. E., Gelperina, S. E., Skidan, I. N., Antropov, A. S., Kivman, G. Y., & Kreuter, J. (1999) · Pharmaceutical Research · doi:10.1023/a:1018983904537 · Cited by 521

A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier

Dehouck, B., Fenart, L., Dehouck, M.-P., Pierce, A., Torpier, G., & Cecchelli, R. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.138.4.877 · Cited by 490

Hyperalgesia Induced by Naloxone Follows Diurnal Rhythm in Responsivity to Painful Stimuli

Frederickson, R. C. A., Burgis, V., & Edwards, J. D. (1977) · Science · doi:10.1126/science.561998 · Cited by 379

Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo.

Pardridge, W. M., Buciak, J. L., & Friden, P. M. (1991) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20567-5 · Cited by 358

Delivery of Loperamide Across the Blood-Brain Barrier with Polysorbate 80-Coated Polybutylcyanoacrylate Nanoparticles

Alyautdin, R. N., Petrov, V. E., Langer, K., Berthold, A., Kharkevich, D. A., & Kreuter, J. (1997) · Pharmaceutical Research · doi:10.1023/a:1012098005098 · Cited by 352

Strategic nanocarriers to control neurodegenerative disorders: Concept, challenges, and future perspective

Ashique, S., Afzal, O., Yasmin, S., Hussain, A., Altamimi, M. A., Webster, T. J., & Altamimi, A. S. A. (2023) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2023.122614 · Cited by 29

Combined strategies of apomorphine diester prodrugs and nanostructured lipid carriers for efficient brain targeting

Liu, K., Wen, C.-J., Yen, T., Sung, K. C., Ku, M.-C., Wang, J., & Fang, J. (2012) · Nanotechnology · doi:10.1088/0957-4484/23/9/095103 · Cited by 28

Peptide Pills for Brain diseases? Reality and Future Perspectives

Serrano, D. R., & Lalatsa, A. (2013) · Therapeutic Delivery · doi:10.4155/tde.13.5 · Cited by 27

Melanocortins, Melanocortin Receptors and Multiple Sclerosis

Lisak, R., & Benjamins, J. (2017) · Brain Sciences · doi:10.3390/brainsci7080104 · Cited by 27

PLGA Nanoparticles for Nose to Brain Delivery of Clonazepam: Formulation, Optimization by 32 Factorial Design, In Vitro and In Vivo Evaluation

Shah, P., Sarolia, J., Vyas, B., Wagh, P., Ankur, K., & Mishra, A. K. (2020) · Current Drug Delivery · doi:10.2174/1567201817666200708115627 · Cited by 28

Combatting Helicobacter pylori with oral nanomedicines

Qin, Y. H., Lao, Y., Wang, H., Zhang, J., Yi, K., Chen, Z., Han, J., Song, W., Tao, Y., & Li, M. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb02038b · Cited by 28

OPTIMIZATION OF RIVASTIGMINE CHITOSAN NANOPARTICLES FOR NEURODEGENERATIVE ALZHEIMER; IN VITRO AND EX VIVO CHARACTERIZATIONS

El-Assal, M. I. A., & SAMUEL, D. (2022) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2022v14i1.43145 · Cited by 27

Formulation and Comparative Characterization of Chitosan, Gelatin, and Chitosan–Gelatin-Coated Liposomes of CPT-11–HCl

Shende, P. K., & Gaud, R. S. (2008) · Drug Development and Industrial Pharmacy · doi:10.1080/03639040802498849 · Cited by 27

Toxicity of metal nanoparticles with a focus on silver

Abramenko, N. B., & Kustov, L. M. (2013) · Mendeleev Communications · doi:10.1016/j.mencom.2013.03.001 · Cited by 26

Docetaxel-Loaded Cholesterol-PEG Co-Modified Poly (n-Butyl) Cyanoacrylate Nanoparticles for Antitumor Drug Pulmonary Delivery: Preparation, Characterization, and in vivo Evaluation

Hu, X., Yang, F., Liao, Y., Li, L., Zhao, G., & Zhang, L. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s249511 · Cited by 26

Epirubicin loaded to pre-polymerized poly(butyl cyanoacrylate) nanoparticles: Preparation and in vitro evaluation in human lung adenocarcinoma cells

Yordanov, G. G., Evangelatov, A., & Skrobanska, R. (2013) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2013.02.002 · Cited by 27

In vivo labelling of hippocampal β‐amyloid in triple‐transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles

Härtig, W., Kacza, J., Paulke, B., Grosche, J., Bauer, U. U. I., Hoffmann, A., Elsinghorst, P. W., & Gütschow, M. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.07038.x · Cited by 26

Novel anionic polymer as a carrier for CNS delivery of anti-Alzheimer drug

Jakki, S. L., Ramesh, Y. V., Gowthamarajan, K., Venkatachalam, S., Jain, K., Sood, S., & Pathak, D. (2016) · Drug Delivery · doi:10.1080/10717544.2016.1196767 · Cited by 26

Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model

Visentin, C., Pellistri, F., Natalello, A., Vertemara, J., Bonanomi, M., Gatta, E., Penco, A., Relini, A., GIOIA, L. D., Airoldi, C., et al. (2017) · Human Molecular Genetics · doi:10.1093/hmg/ddx211 · Cited by 26

Evolution of Theories on Doxorubicin-Induced Late Cardiotoxicity-Role of Topoisomerase

Szponar, J., Ciechański, E., Ciechańska, M., Dudka, J., & Mańdziuk, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413567 · Cited by 27

In vitro and in vivo Effects of Free and Chalcones-Loaded Nanoemulsions: Insights and Challenges in Targeted Cancer Chemotherapies

Winter, E., Pizzol, C. D., Locatelli, C., Silva, A. H., Conte, A., Chiaradia-Delatorre, L. D., Nunes, R. J., Yunes, R. A., & Creckzynski-Pasa, T. (2014) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph111010016 · Cited by 25

Interaction of pHPMA–pLMA Copolymers with Human Blood Serum and Its Components

Hemmelmann, M., Mohr, K., Fischer, K., Zentel, R., & Schmidt, M. (2013) · Molecular Pharmaceutics · doi:10.1021/mp400254b · Cited by 24

Effect of Surfactant Coating on Brain Targeting Polymeric Nanoparticles; a Review

Chacko, B., Palanisamy, S., Gowrishankar, N. L., Honeypriya, J., & Sumathy, A. S. D. A. (2018) · Indian Journal of Pharmaceutical Sciences · doi:10.4172/pharmaceutical-sciences.1000348 · Cited by 25

Analyzing Nanotheraputics-Based Approaches for the Management of Psychotic Disorders

Annu, Rehman, S., Md, S., Baboota, S., & Ali, J. (2019) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2019.08.027 · Cited by 25

Albumin nanoparticles coated with polysorbate 80 for the targeted delivery of antiepileptic drug levetiracetam into the brain

Wilson, B., Selvam, J. P., Geetha, K. M., Premakumari, K. B., & Jenita⃰, J. J. L. (2020) · Drug Delivery and Translational Research · doi:10.1007/s13346-020-00831-3 · Cited by 25

Salinomycin encapsulated nanoparticles as a targeting vehicle for glioblastoma cells

Aydın, R. S. T., Bayrak, G. K., & Gümüşderelı́oğlu, M. (2015) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35591 · Cited by 25

Evaluation of thein vitrodifferential protein adsorption patterns of didanosine-loaded nanostructured lipid carriers (NLCs) for potential targeting to the brain

Kasongo, K. W., Jansch, M., Müller, R. H., & Walker, R. B. (2010) · Journal of Liposome Research · doi:10.3109/08982104.2010.539186 · Cited by 25

Fabrication via a nonaqueous nanoprecipitation method, characterization and in vitro biological behavior of N6-cyclopentyladenosine-loaded nanoparticles

Dalpiaz, A., Vighi, E., Pavan, B., & Leo, E. (2009) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21710 · Cited by 25

New celecoxib multiparticulate systems to improve glioblastoma treatment

Vera, M. R., Barcia, E., Negro, S., Marcianes, P., García‐García, L., Slowing, K., & Fernández-Carballido, A. M. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.07.028 · Cited by 25

A Comparative Study of Orally Delivered PBCA and ApoE Coupled BSA Nanoparticles for Brain Targeting of Sumatriptan Succinate in Therapeutic Management of Migraine

Girotra, P., & Singh, S. K. (2016) · Pharmaceutical Research · doi:10.1007/s11095-016-1910-8 · Cited by 25

Quantitative analysis of nanoparticle transport through in vitro blood-brain barrier models

Åberg, C. (2016) · Tissue Barriers · doi:10.1080/21688370.2016.1143545 · Cited by 27

Nanoparticle-mediated delivery of Neurotoxin-II to the brain with intranasal administration: an effective strategy to improve antinociceptive activity of Neurotoxin

Ruan, Y., Li, Y., Zhang, B., Zhang, S.-J., & Guo, J. (2011) · Drug Development and Industrial Pharmacy · doi:10.3109/03639045.2011.592533 · Cited by 25

Therapeutic nanotechnologies for Alzheimer’s disease: A critical analysis of recent trends and findings

Delbreil, P., Rabanel, J., Banquy, X., & Brambilla, D. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114397 · Cited by 25

Fe3O4 nanoparticles with daunorubicin induce apoptosis through caspase 8-PARP pathway and inhibit K562 leukemia cell-induced tumor growth in vivo

Zhang, G., Lai, B. B., Zhou, Y., Chen, B. A., Wang, X. M., Lu, Q., & Chen, Y. (2011) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2011.01.013 · Cited by 24

Experimental therapies

Hulou, M. M., Cho, C., Chiocca, E. A., & Bjerkvig, R. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-802997-8.00011-6 · Cited by 24

Effect of the development of a cell barrier on nanoparticle uptake in endothelial cells

Francia, V., Aliyandi, A., & Salvati, A. L. (2018) · Nanoscale · doi:10.1039/c8nr03171a · Cited by 25

Pharmacoresistance

Potschka, H., & Brodie, M. J. (2012) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52899-5.00025-3 · Cited by 24

Nanopharmaceuticals to target antifilarials: a comprehensive review

Ali, M., Afzal, M., Bhattacharya, S. M., Ahmad, F. J., & Dinda, A. K. (2013) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2013.771630 · Cited by 24

An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood–brain barrier uptake

Bode, G. H., Coué, G. M. J. P. C., Freese, C., Pickl, K. E., Sánchez-Purrà, M., Albaiges, B., Borrós, S., van Winden, E. C. A., Tziveleka, L., Sideratou, Z., et al. (2016) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2016.11.009 · Cited by 24

Brain Targeting Nanomedicines: Pitfalls and Promise

Käkinen, A., Jiang, Y., Davis, T. P., Teesalu, T., & Saarma, M. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s454553 · Cited by 26

Lipid Nanoparticles for Brain Tumor Theranostics: Challenges and Status

Kaur, N., Gautam, P., Nanda, D., Meena, A. S., Shanavas, A., & Prasad, R. (2024) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.4c00293 · Cited by 23

A Spontaneous Membrane-Adsorption Approach to Enhancing Second Near-Infrared Deep-Imaging-Guided Intracranial Tumor Therapy

Li, L., Zhang, B., Liu, Y. L., Gao, R.-Y., Zhou, J., Fu, L., & Wang, J. (2021) · ACS Nano · doi:10.1021/acsnano.0c08532 · Cited by 23

From Conventional to Cutting-edge: A Comprehensive Review on Drug Delivery Systems

Vikal, A., Maurya, R., Bhowmik, S., Patel, P., Gupta, G. D., & Kurmi, B. D. (2024) · Drug Delivery Letters · doi:10.2174/0122103031304556240430161553 · Cited by 24

The Effect of Ventilation, Age, and Asthmatic Condition on Ultrafine Particle Deposition in Children

Olvera, H. A., Perez, D., Clague, J. W., Cheng, Y., Li, W.-W., Amaya, M. A., Burchiel, S. W., Berwick, M., & Pingitore, N. E. (2012) · Pulmonary Medicine · doi:10.1155/2012/736290 · Cited by 25

Surface-Modified PLGA Nanoparticles for Targeted Drug Delivery to Neurons

Mehta, T. A., Shah, N., Parekh, K., Dhas, N. L., & Patel, J. K. (2019) · Springer eBooks · doi:10.1007/978-3-030-06115-9_3 · Cited by 23

Development of iron chelator–nanoparticle conjugates as potential therapeutic agents for Alzheimer disease

Liu, G., Men, P., Perry, G. L., & Smith, M. A. (2009) · Progress in brain research · doi:10.1016/s0079-6123(08)80005-2 · Cited by 22

Effect of anticoagulants on the protein corona-induced reduced drug carrier adhesion efficiency in human blood flow

Sobczynski, D. J., & Eniola‐Adefeso, O. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.10.023 · Cited by 22

A new preparation strategy for surface modified PLA nanoparticles to enhance uptake by endothelial cells

Raudszus, B., Mulac, D., & Langer, K. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.11.047 · Cited by 22

Enhancement of mitochondrial function using NO releasing nanoparticles; a potential approach for therapy of Alzheimer’s disease

Samir, M., Abdel-Kader, R. M., Boushehri, M. A. S., Mansour, S., Lamprecht, A., & Tammam, S. N. (2023) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2023.01.006 · Cited by 23

Gene therapy approaches for lysosomal storage disorders, a good model for the treatment of mendelian diseases

Tomanin, R., Zanetti, A., Zaccariotto, E., D’Avanzo, F., Bellettato, C. M., & Scarpa, M. (2012) · Acta Paediatrica · doi:10.1111/j.1651-2227.2012.02674.x · Cited by 22

Brain pharmacokinetics of neurotoxin-loaded PLA nanoparticles modified with chitosan after intranasal administration in awake rats

Zhang, X., Liu, L., Chai, G., Zhang, X., & Li, F. (2013) · Drug Development and Industrial Pharmacy · doi:10.3109/03639045.2012.727828 · Cited by 22

Comparative evaluation of the degree of pegylation of poly(lactic-co-glycolic acid) nanoparticles in enhancing central nervous system delivery of loperamide

Kirby, B. P., Pabari, R. M., Chen, C.-N., Baharna, M. A., Walsh, J., & Ramtoola, Z. (2013) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12125 · Cited by 22

Protein Adsorption Patterns and Analysis on IV Nanoemulsions—The Key Factor Determining the Organ Distribution

Keck, C. M., Jansch, M., & Müller, R. H. (2012) · Pharmaceutics · doi:10.3390/pharmaceutics5010036 · Cited by 22

DNA Amplification via Polymerase Chain Reaction Inside Miniemulsion Droplets with Subsequent Poly(n‐butylcyanoacrylate) Shell Formation and Delivery of Polymeric Capsules into Mammalian Cells

Baier, G., Musyanovych, A., Landfester, K., Best, A., Lorenz, S., & Mailänder, V. (2011) · Macromolecular Bioscience · doi:10.1002/mabi.201100003 · Cited by 22

Penetration and intracellular uptake of poly(glycerol-adipate) nanoparticles into three-dimensional brain tumour cell culture models

Meng, W., Garnett, M. C., Walker, D. A., & Parker, T. L. (2015) · Experimental Biology and Medicine · doi:10.1177/1535370215610441 · Cited by 23

Nanometre scale hydroxyapatite ceramics for bone tissue engineering

Poinern, G. E. J., Brundavanam, R. K., & Fawcett, D. (2013) · Murdoch University Research Portal · Cited by 22

The augmented anticancer potential of AP9-cd loaded solid lipid nanoparticles in human leukemia Molt-4 cells and experimental tumor

Bhushan, S., Kakkar, V., Pal, H. C., Mondhe, D. M., & Kaur, I. P. (2015) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2015.11.022 · Cited by 22

Nanoparticles for tumor targeting

Jiang, T., Jin, K., Liu, X., & Pang, Z. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-101914-6.00008-9 · Cited by 22

Brain targeted delivery of sumatriptan succinate loaded chitosan nanoparticles: Preparation, In vitro characterization, and (Neuro-)pharmacokinetic evaluations

Masjedi, M., Azadi, A., Heidari, R., & Mohammadi‐Samani, S. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.102179 · Cited by 21

Pharmacokinetics and tissue distribution of etoposide delivered in long circulating parenteral emulsion

Reddy, P. R., & Venkateswarlu, V. (2005) · Journal of drug targeting · doi:10.1080/10611860500403156 · Cited by 21

Nanocarrier-based therapies for CNS tumors

Patel, T. (2014) · CNS Oncology · doi:10.2217/cns.14.2 · Cited by 21

Advances in Brain Targeted Drug Delivery: Nanoparticulate Systems

Joseph, E., & Saha, R. N. (2013) · Cited by 21

Polymer Nanomaterials for Drug Delivery Across the Blood Brain Barrier

Kabanov, A. V., & Batrakova, E. V. (2016) · Springer eBooks · doi:10.1007/978-3-319-44022-4_50 · Cited by 21

Identification and characterization of highly versatile peptide-vectors that bind non-competitively to the low-density lipoprotein receptor for in vivo targeting and delivery of small molecules and protein cargos

David, M., Lécorché, P., Masse, M., Faucon, A., Abouzid, K., Gaudin, N., Varini, K., Gassiot, F., Ferracci, G., Jacquot, G., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191052 · Cited by 23

Chitosan-alginate core-shell-corona shaped nanoparticles of dimethyl fumarate in orodispersible film to improve bioavailability in treatment of multiple sclerosis: Preparation, characterization and biodistribution in rats

Sinha, S., Garg, V., Sonali, Singh, R. P., & Dutt, R. (2021) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2021.102645 · Cited by 21

Conventional Chemotherapeutic Drug Nanoparticles for Cancer Treatment

Serpe, L. (2003) · Nanotechnologies for the Life Sciences · doi:10.1002/9783527610419.ntls0060 · Cited by 21

Oral delivery of brain-targeted miltefosine-loaded alginate nanoparticles functionalized with polysorbate 80 for the treatment of cryptococcal meningitis

Spadari, C. D. C., Lanser, D. M., de Araújo, M. V., de Jesus, D. F. F., Lopes, L. B., Gelli, A., & Ishida, K. (2023) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkad053 · Cited by 20

Non-conventional compounds with potential therapeutic effects against Alzheimer’s disease

de Castro, A. A., Soares, F. V., Pereira, A. F., Polisel, D. A., Caetano, M. S., Leal, D. H. S., da Cunha, E. F. F., Nepovimová, E., Kuča, K., & Ramalho, T. C. (2019) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2019.1608823 · Cited by 20

Fluorinated Molecules and Nanotechnology: Future ‘Avengers’ against the Alzheimer’s Disease?

Dabur, M., Loureiro, J. A., & Pereira, M. D. C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082989 · Cited by 20

Effects of Graphene-Based Materials on the Behavior of Neural Stem Cells

Zhang, Y., Wang, S., & Yang, P. C. (2020) · Journal of Nanomaterials · doi:10.1155/2020/2519105 · Cited by 22

BioNanotechnology

Papazoglou, E. S., & Parthasarathy, A. (2007) · Synthesis lectures on biomedical engineering · doi:10.2200/s00051ed1v01y200610bme007 · Cited by 20

Solid lipid nanoparticles for brain tumors therapy

Brioschi, A., Calderoni, S., Zara, G. P., Priano, L., Gasco, M. R., & Mauro, A. (2009) · Progress in brain research · doi:10.1016/s0079-6123(08)80011-8 · Cited by 21

Nanostructured Biomaterials and Their Applications

Parratt, K. H., & Yao, N. (2013) · Nanomaterials · doi:10.3390/nano3020242 · Cited by 20

Enhanced delivery of γ-secretase inhibitor DAPT into the brain via an ascorbic acid mediated strategy

Quéléver, G., Kachidian, P., Melon, C., Garino, C., Laras, Y., Pietrancosta, N., Sheha, M. M., & Kraus, J. L. (2005) · Organic & Biomolecular Chemistry · doi:10.1039/b504988a · Cited by 20

Sodium alginate nanoparticles as a new transdermal vehicle of glucosamine sulfate for treatment of osteoarthritis

El-Houssiny, A. S., Ward, A. A., Mostafa, D. M., Abd‐El‐Messieh, S. L., Abd‐El‐Nour, K. N., Darwish, M. M., & Khalil, W. A. (2017) · European Journal of Nanomedicine · doi:10.1515/ejnm-2017-0008 · Cited by 20

A new strategy for specific imaging of neural cells based on peptide-conjugated gold nanoclusters

Fu, A., & Zhang, E. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s78554 · Cited by 19

Utilization and Characterization of Oyster Shell as Chitosan and Nanochitosan

Handayani, L., Syahputra, F., & Astuti, Y. (2018) · Jurnal Kimia Sains dan Aplikasi · doi:10.14710/jksa.21.4.224-231 · Cited by 19

Multiple-component dual-phase solid lipid nanoparticles with conjugated transferrin for formulating antioxidants and nerve growth factor against neuronal apoptosis

Kuo, Y., Lou, Y.-I., Rajesh, R., & Chen, C.-L. (2020) · Journal of the Taiwan Institute of Chemical Engineers · doi:10.1016/j.jtice.2020.02.017 · Cited by 19

Neuroprotective Effect of Ultrasound Triggered Astaxanthin Release Nanoparticles on Early Brain Injury After Subarachnoid Hemorrhage

Cai, W., Wu, Q., Yan, Z. Z., He, W., Zhou, X., Zhou, L., Zhang, J., & Zhang, X. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.775274 · Cited by 20

Distribution of an intravenous injectable nimodipine nanosuspension in mice

Xiong, R., Lu, W., Peng, Y., Xu, R., Li, J., Chen, T., & Wang, P. (2008) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.60.9.0006 · Cited by 19

Targeted and theranostic applications for nanotechnologies in medicine

Setua, S., Jaggi, M., Yallapu, M. M., Chauhan, S. C., Aleksandrovna, D. A., Lee, H., Choi, I. S., Fakhrullin, R. F., Esposti, L. D., Tampieri, A., et al. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-48063-5.00006-x · Cited by 20

Non-agglomerated silicon–organic nanoparticles and their nanocomplexes with oligonucleotides: synthesis and properties

Levina, A. S., Николаевна, Р. М., Васильевна, Ш. Н., Ismagilov, Z. R., Yashnik, S. A., Semenov, D. V., Savinovskaya, Y. I., Mazurkova, N. A., Pyshnaya, I. A., & Zarytova, V. F. (2018) · Beilstein Journal of Nanotechnology · doi:10.3762/bjnano.9.234 · Cited by 19

In situ characterization of nanoparticles during growth by means of white light scattering

Mitic, S., Pustylnik, M., Morfill, G. E., & Kovačević, E. (2011) · Optics Letters · doi:10.1364/ol.36.003699 · Cited by 18

Image-guided drug delivery to the brain using nanotechnology

Ding, H. Y., Wu, F. P., & Nair, M. (2013) · Drug Discovery Today · doi:10.1016/j.drudis.2013.06.010 · Cited by 19

Protective Effects of Poly (butyl) Cyanoacrylate Nanoparticles Containing Vasoactive Intestinal Peptide Against 6-Hydroxydopamine-Induced Neurotoxicity In Vitro

Xu, Z., Wang, W.-F., Liang, X., Liu, Z., Liu, Y., Liang, L., & Zhu, X. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0438-9 · Cited by 18

Advances in brain targeting and drug delivery of anti-HIV therapeutic agents

Al-Ghananeem, A. M., Smith, M. B. H., Coronel, M. L., & Tran, H. V. (2013) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2013.781999 · Cited by 18

Nanoparticles for Pulmonary Delivery

Watts, A. B., & Williams, R. O. (2011) · Springer eBooks · doi:10.1007/978-1-4419-9745-6_15 · Cited by 18

Octamers and nanoparticles as hemoglobin based blood substitutes

Baudin‐Creuza, V., Chauvierre, C., Domingues‐Hamdi, E., Kiger, L., Leclerc, L., Vasseur, C., Célier, C., & Marden, M. C. (2008) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2008.02.005 · Cited by 18

RNA nanotechnology: A new chapter in targeted therapy

Lv, T., Meng, Y., Liu, Y., Han, Y., Xin, H., Peng, X., & Huang, J. (2023) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2023.113533 · Cited by 17

Drug Delivery to the CNS and Polymeric Nanoparticulate Carriers

Costantino, L. (2010) · Future Medicinal Chemistry · doi:10.4155/fmc.10.249 · Cited by 18

Nanoparticulate strategies for the treatment of polyglutamine diseases by halting the protein aggregation process

Escalona-Rayo, O., Fuentes-Vázquez, P., Leyva‐Gómez, G., Cisneros, B., Villalobos, R., Magaña, J. J., & Quintanar‐Guerrero, D. (2017) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2017.1281949 · Cited by 17

Inorganic nanoparticles for theranostic use

Esposti, L. D., Carella, F., & Iafisco, M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-08-101745-6.00017-7 · Cited by 17

Preparation of polymersomes from synthesized hyaluronic acid-graft-poly(ε-caprolactone) copolymers for drug delivery to the brain

Kiani-Dehkordi, B., Vatanara, A., Amini, M., Hamidi, M., Dibaei, M., Norouzi, P., Rezaei, S. J. T., Khoshnazar, A., & Rouini, M. R. (2023) · Materials Today Chemistry · doi:10.1016/j.mtchem.2023.101504 · Cited by 17

Recent prospective of surface engineered Nanoparticles in the management of Neurodegenerative disorders

Singh, D., Kapahi, H., Rashid, M., Prakash, A. K., Majeed, A. B. A., & Mishra, N. (2015) · Artificial Cells Nanomedicine and Biotechnology · doi:10.3109/21691401.2015.1029622 · Cited by 17

In vivobrain microdialysis to evaluate FITC-dextran encapsulated immunopegylated nanoparticles

Bommana, M. M., Kirthivasan, B., & Squillante, E. (2012) · Drug Delivery · doi:10.3109/10717544.2012.714812 · Cited by 17

Combined synthesis and in situ coating of nanoparticles in the gas phase

Lähde, A., Raula, J., & Kauppinen, E. I. (2008) · Journal of Nanoparticle Research · doi:10.1007/s11051-008-9399-7 · Cited by 17

Surface coverage of didecyl dimethylammonium bromide on poly(lactide-co-glycolide) nanoparticles

Kuo, Y., & Yu, H.-W. (2011) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2011.01.009 · Cited by 17

Targeting and Triggered Release Using Lipid-Based Supramolecular Assemblies as Medicinal Nanocarriers

Alam, S., Mattern‐Schain, S. I., & Best, M. D. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.12540-5 · Cited by 17

Nanotechnology and Its Drug Delivery Applications

Bhatia, S. (2016) · Springer eBooks · doi:10.1007/978-3-319-41129-3_1 · Cited by 17

Substituted thiazolamide coupled to a redox delivery system: a new γ-secretase inhibitor with enhanced pharmacokinetic profile

Laras, Y., Quéléver, G., Garino, C., Pietrancosta, N., Sheha, M. M., Bihel, F. J. ‐., Wolfe, M. S., & Kraus, J. (2005) · Organic & Biomolecular Chemistry · doi:10.1039/b415090b · Cited by 17

Nanoparticles: A Closer Look at the Risks to Human Health and the Environment Perceptions and Precautionary Measures of Industry and Regulatory Bodies in Europe

Helland, A. (2004) · Lund University Publications Student Papers (Lund University) · Cited by 17

Nose-to-brain lipid nanocarriers: An active transportation across BBB in migraine management

Kataria, I., & Shende, P. K. (2022) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2022.105177 · Cited by 16

Nanotechnology Based Targeted Drug Delivery: Current Status and Future Prospects for Drug Development

Sharma, S., & Singh, A. (2011) · InTech eBooks · doi:10.5772/28902 · Cited by 16

Pharmacokinetics and tissue distribution of larotaxel in rats: comparison of larotaxel-loaded microsphere with larotaxel-solution

Liu, Z., Feng, Y., Zhang, L., Li, G., Geng, L., Cui, Y., Teng, F., Tang, X., Bi, K., & Chen, X. (2013) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-013-2104-2 · Cited by 16

Beyond the Blood–Brain Barrier

Kumar, M., Sharma, P. A., Maheshwari, R., Tekade, M., Shrivastava, S. K., & Tekade, R. K. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812218-1.00015-4 · Cited by 16

Application of nanoparticles for the delivery of drugs to the brain

Kreuter, J. (2005) · International Congress Series · doi:10.1016/j.ics.2005.02.014 · Cited by 107

Transport of drugs across the blood–brain barrier by nanoparticles.

Wohlfart, S., Gelperina, S., & Kreuter, J. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.08.017 · Cited by 715

Use of nanoparticles to deliver therapeutics to the CNS

Kreuter, J. (2010) · Frontiers in Pharmacology · doi:10.3389/conf.fphar.2010.02.00024

Influence of the Surface Properties on Nanoparticle-Mediated Transport of Drugs to the Brain

Kreuter, J. (2004) · Journal of Nanoscience and Nanotechnology · doi:10.1166/jnn.2003.077 · Cited by 363

Mechanism of polymeric nanoparticle-based drug transport across the blood-brain barrier (bbb).

Kreuter, J. (2013) · Journal of Microencapsulation · doi:10.3109/02652048.2012.692491 · Cited by 172