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Cited by 202

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Evaluation of nano- and microparticle uptake by the gastrointestinal tract

Open access
Delie, F·1998·Advanced Drug Delivery Reviews

Abstract

Numerous papers over the last two decades have demonstrated that particle uptake by the gastrointestinal tract is a reality. In addition, polymeric nano- and microparticles have proved to be useful delivery systems to enhance oral bioavailability of poorly absorbed drugs or to induce mucosal immune response. However, despite the amount of data available, no set criteria are available for the design of a good particulate carrier for oral delivery of peptides or antigens. This is partly due to the publication of conflicting and confusing data. The source of discrepancy is actually multiparametric (e.g., methodology, mode of evaluation, animal species) and is still not fully understood. The purpose of this review is to discuss the advantages and the limitations of the methodologies and the models used to evaluate gastrointestinal uptake of nano- and microparticles.

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Crossref · 10.1016/s0169-409x(98)00041-6

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Metadata

Authors
Delie, F.
Venue
Advanced Drug Delivery Reviews
Publisher
Elsevier BV
Published
1998-12-01
Volume
34
Issue
2-3
Pages
221-233
ISSN
0169-409X (ISSN-L)
OpenAlex
W1998525713
Cited by
202
References
5
FWCI
3.24
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Evaluation of nano- and microparticle uptake by the gastrointestinal tract. https://app.cochat.ai/papers/10.1016/s0169-409x(98)00041-6
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Delie, F. (1998). Evaluation of nano- and microparticle uptake by the gastrointestinal tract. Advanced Drug Delivery Reviews. https://doi.org/10.1016/s0169-409x(98)00041-6

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.