The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Pain in ambulatory AIDS patients. I: Pain characteristics and medical correlates
Abstract
The characteristics and impact of pain were evaluated in a prospective cross-sectional survey of 438 ambulatory AIDS patients recruited from health care facilities in New York City. More than 60% of the patients reported 'frequent or persistent pain' during the 2 wks preceding the study. Patients with pain reported an average of 2.5 different pains. On the 0-10 numerical scale of the Brief Pain Inventory (BPI), mean pain intensity 'on average' was 5.4 (SD = 2.2; range = 0-10), and mean pain 'at its worst' was 7.4 (SD = 2.0; range = 1-10). The pain-related functional interference index (sum of the seven item BPI subscale) was 42.6 (SD = 17.2; range = 0.70). Demographic variables were not associated with the presence of pain, but the number of current HIV-related symptoms, treatment for HIV-related infections, and the absence of antiretroviral medications were significantly associated with the presence of pain. Female gender, non-Caucasian race, and number of HIV-related physical symptoms were significantly associated with pain intensity. Presence of pain and increasing pain intensity were significantly associated with greater impairment in functional ability (Karnofsky Performance Status, BPI functional interference index) and physical symptom distress (Memorial Symptom Assessment Scale). Results demonstrate high levels of pain and pain-related functional impairment among patients with AIDS. The presence and intensity of pain are associated with more advanced HIV disease and pain intensity is also associated with demographic factors (gender, race).
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“emotional distress and psychosocial stress have been shown to increase the likelihood of transitioning from acute to chronic musculoskeletal pain 18, 36, 37, 41, 42.”
From Evaluating psychosocial contributions to chronic pain outcomes (2018) · cites this paper as [37]
In the citing paper
“prospective studies suggest that pre-morbid psychological dysfunction represents a risk factor for the future development of numerous chronic pain conditions including musculoskeletal pain and functional pain disorders 14, 36–39.”
From Evaluating psychosocial contributions to chronic pain outcomes (2018) · cites this paper as [37]
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BackgroundDefining racial and ethnic disparities in pain management
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InfluentialMilligan, E. D., Mehmert, K. K., Hinde, J. L., Harvey, L. O., Martin, D., Tracey, K. J., Maier, S. F., & Watkins, L. R. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02050-3 · Cited by 279
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Pain in people living with HIV/AIDS: a systematic review
Parker, R., Stein, D. J., & Jelsma, J. M. (2014) · Journal of the International AIDS Society · doi:10.7448/ias.17.1.18719 · Cited by 232
“The majority (19) of the studies were conducted in high-income countries with fourteen from the United States; one from Canada; one from France; one from Denmark; one from Sweden; and one from Italy.”
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Vogl, D. T., Rosenfeld, B. D., BREITBART, W. S., Thaler, H. T., Passik, S. D., McDonald, M. V., & Portenoy, R. K. (1999) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(99)00066-4 · Cited by 204
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MethodAccuracy of recall of usual pain intensity in back pain patients
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Rosenfeld, B. D., BREITBART, W. S., McDonald, M. V., Passik, S. D., Thaler, H. T., & Portenoy, R. K. (1996) · Pain · doi:10.1016/s0304-3959(96)03220-4 · Cited by 130
“The complex nature of suicidal ideation in medically ill patients has been observed previously (Breitbart 1993; Breitbart et al. 1996c), and these data support the hypothesis that the relationship between pain and suicidal ideation is indirect.”
InfluentialSelf-citationTopical Capsaicin in the Management of HIV-Associated Peripheral Neuropathy
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Umbricht, A., Hoover, D. R., TUCKER, M., Leslie, J. M., Chaisson, R. E., & Preston, K. L. (2003) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00325-3 · Cited by 59
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Namisango, E., Harding, R., Atuhaire, L. K., Ddungu, H., Katabira, E., Muwanika, F. R., & Powell, R. A. (2012) · Journal of Pain · doi:10.1016/j.jpain.2012.04.007 · Cited by 52
Transcending the physical: spiritual aspects of pain in patients with HIV and/or cancer
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Jeevanjee, S., Penko, J. M., Guzman, D., Miaskowski, C. A., Bangsberg, D. R., & Kushel, M. (2013) · AIDS and Behavior · doi:10.1007/s10461-013-0619-5 · Cited by 51
Access and equity in HIV/AIDS palliative care: a review of the evidence and responses
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Orofacial Pain: Racial and Sex Differences Among Older Adults
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Trafton, J. A., Sorrell, J. T., Holodniy, M., Pierson, H., Link, P., Combs, A., & Israelski, D. (2012) · The Journal of Behavioral Health Services & Research · doi:10.1007/s11414-011-9254-y · Cited by 48
“The impact includes increasing depression, psychological distress, and health care utilization and decreasing functional ability, and quality of life.(1,4,6) Prescribing opioid and anti-inflammatory medications is often the first and primary response to chronic pain complaints in primary care.”
BackgroundCervia, L. D., McGowan, J. P., & Weseley, A. J. (2010) · Pain Medicine · doi:10.1111/j.1526-4637.2010.00802.x · Cited by 49
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Self-citationChemotherapy-Induced Peripheral Neuropathy (CIPN): A Narrative Review and Proposed Theoretical Model
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“Racial and ethnic differences have been identified in a wide range of chronic pain conditions, including post-surgical pain [46], knee osteoarthritis [47,48], and HIV/AIDS pain [49].”
BackgroundKeltner, J. R., Vaida, F., Ellis, R. J., Moeller‐Bertram, T., Sanders, C., Duarte, N. A., Robinson‐Papp, J., Dworkin, R. H., Clifford, D. B., McArthur, J. C., et al. (2012) · Psychosomatics · doi:10.1016/j.psym.2012.05.002 · Cited by 45
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“Black patients and Black patients with chronic diseases such as Crohn's disease, asthma, and acquired immune deficiency syndrome (AIDS) tend to report worse physical functioning and health status than comparable White patients [11-15].”
BackgroundHopelessness and terminal illness: The construct of hopelessness in patients with advanced AIDS
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“Breitbart et al.(3) examined the medical characteristics of 438 ambulatory AIDS patients and found that over 60% reported frequent or persistent pain, and the “on average” pain intensity was in the moderate range.”
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Experience of Pain among Women with Advanced HIV Disease
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“Estimates suggest that more than 60% of HIV patients report frequent and persistent pain (Breitbart et al. 1996).”
BackgroundInvestigating patient characteristics on pain assessment using virtual human technology
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“Clinically, compared to other race/ethnic groups, African–Americans report higher levels of pain in conditions such as AIDS (Breitbart et al., 1996), glaucoma (Sherwood et al., 1998), ernational Association for the Stud migraine headaches (Stewart et al., 1996), and post-surgery (White et al., 1999).”
BackgroundÖnen, N. F., Barrette, E., Shacham, E., Taniguchi, T., Donovan, M., & Overton, E. T. (2011) · Pain Practice · doi:10.1111/j.1533-2500.2011.00520.x · Cited by 41
Knowing How to Play the Game: Hospitalized Substance Abusers’ Strategies for Obtaining Pain Relief
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A sociocultural neuroscience approach to pain
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“…to multiple experimental pain modalities (Campbell et al. 2008; Edwards and Fillingim 1999; Mechlin et al. 2005; Rahim-Williams et al. 2007) and clinical conditions (Breitbart et al. 1996; Creamer et al. 1999; Edwards and Fillingim 1999; Green et al. 2003; Greenwald 1991; Riley et al. 2002).”
BackgroundLipman, A. G. (2005) · Journal of Pain & Palliative Care Pharmacotherapy · doi:10.1080/j354v19n03_16 · Cited by 38
Pain, psychological symptoms and prescription drug misuse in HIV: A literature review.
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“[13] Breitbart W, McDonald MV, Rosenfeld B, Passik SD, Hewitt D,”
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A Mixed Methods Study of Patient-Provider Communication about Opioid Analgesics
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“One study reported that IDUs were 1.8 times more likely to receive inadequate analgesia compared to non-IDUs (Breitbart et al., 1996b).”
BackgroundResultInfluentialSex Differences in a Rodent Model of HIV-1-Associated Neuropathic Pain
Guindon, J., Blanton, H. L., Brauman, S., Donckels, K., Narasimhan, M., & Benamar, K. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051196 · Cited by 34
Positive futures? The impact of HIV infection on achieving health, wealth and future planning
Harding, R., & Molloy, T. (2008) · AIDS Care · doi:10.1080/09540120701867222 · Cited by 34
“The standardised Memorial Symptom Assessment Schedule Short Form (MSASSF) was included (Breitbart et al., 1996; Chang, Hwang, Feurerman, Kasimis, & Thaler, 2000; Vogl et al., 1999), a well-validated multidimensional symptom assessment instrument capturing 7-day prevalence and burden of 26 physical symptoms and 4 psych…”
Method
Metadata
- Authors
- Breitbart, W., McDonald, M. V., Rosenfeld, B., Passik, S. D., Hewitt, D., Thaler, H., & Portenoy, R. K.
- Affiliations
- Memorial Sloan Kettering Cancer Center (US)
- Corresponding author
- Breitbart, William
- Venue
- Pain
- Published
- 1996-12
- Volume
- 68
- Issue
- 2
- Pages
- 315-321
- ISSN
- 0304-3959 (ISSN-L)
- OpenAlex
- W2026706271
- Cited by
- 204
- References
- 16
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 8 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 8 · 2016: 8 · 2015: 5 · 2014: 8 · 2013: 11 · 2012: 8
- FWCI
- 10.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pain (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh049034-03)
- National Institute of Mental Health (MH-49034)
- Topics
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Infectious Diseases › HIV-related health complications and treatments
- Keywords
- HIV infection, pain intensity, functional disability, Brief Pain Inventory, Karnofsky performance status, Memorial Symptom Assessment Scale, HIV-related symptoms, antiretroviral therapy, demographic factors, gender differences, racial differences, outpatients
- MeSH terms
- Acquired Immunodeficiency Syndrome, Adolescent, Adult, Aged, Ambulatory Care, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Pain Measurement, Predictive Value of Tests, Prospective Studies, Quality of Life, Regression Analysis, Reproducibility of Results, Logistic Models, Karnofsky Performance Status
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