The fragile x mental retardation protein binds and regulates a novel class of mRNAs containing u rich target sequences

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

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Absence of expression of the FMR-1 gene in fragile X syndrome

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Monovalent cation-induced structure of telomeric DNA: The G-quartet model

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Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

Brown, V., Jin, P., Ceman, S., Darnell, J. C., O'Donnell, W. T., Tenenbaum, S. A., Jin, X., Feng, Y., Wilkinson, K. D., Keene, J. D., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00568-2 · Cited by 1,109

Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits

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Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

Darnell, J. C., Jensen, K. B., Jin, P., Brown, V., Warren, S. T., & Darnell, R. B. (2001) · Cell · doi:10.1016/s0092-8674(01)00566-9 · Cited by 952

Interspersed repeats and other mementos of transposable elements in mammalian genomes

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Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits.

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FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding

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DNA methylation represses FMR-1 transcription in fragile X syndrome

Sutcliffe, J. S., Nelson, D. L., Zhang, F., Pieretti, M., Caskey, C. T., Saxe, D., & Warren, S. T. (1992) · Human Molecular Genetics · doi:10.1093/hmg/1.6.397 · Cited by 680

The Fragile X Syndrome Protein FMRP Associates with BC1 RNA and Regulates the Translation of Specific mRNAs at Synapses

Zalfa, F., Giorgi, M., Primerano, B., Moro, A., Di Penta, A., Reis, S., Oostra, B., & Bagni, C. (2003) · Cell · doi:10.1016/s0092-8674(03)00079-5 · Cited by 676

Drosophila Fragile X-Related Gene Regulates the MAP1B Homolog Futsch to Control Synaptic Structure and Function

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Evidence that fragile X mental retardation protein is a negative regulator of translation

Laggerbauer, B. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.4.329 · Cited by 571

Abnormal Development of Dendritic Spines in FMR1 Knock-Out Mice

Nimchinsky, E. A., Oberlander, A. M., & Svoboda, K. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05139.2001 · Cited by 560

Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes.

Feng, Y., Gutekunst, C.-A., Eberhart, D. E., Yi, H., Warren, S. T., & Hersch, S. M. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-05-01539.1997 · Cited by 532

Analysis of neocortex in three males with the Fragile X syndrome

Hinton, V. J., Brown, W. T., Wisniewski, K., & Rudelli, R. D. (1991) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320410306 · Cited by 527

RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice

Miyashiro, K. Y., Beckel-Mitchener, A., Purk, T. P., Becker, K. G., Barret, T., Liu, L., Carbonetto, S., Weiler, I. J., Greenough, W. T., & Eberwine, J. (2003) · Neuron · doi:10.1016/s0896-6273(03)00034-5 · Cited by 495

The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif

Schaeffer, C., Bardoni, B., Mandel, J., Ehresmann, B., Ehresmann, C., & Moine, H. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.4803 · Cited by 471

The fragile X mental retardation protein inhibits translation via interacting with mRNA

Li, Z. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.11.2276 · Cited by 448

L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes

Murphy, T. H., Worley, P. F., & Baraban, J. M. (1991) · Neuron · doi:10.1016/0896-6273(91)90375-a · Cited by 423

Microtubule organization and dynamics dependent on microtubule-associated proteins

Hirokawa, N. (1994) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(94)90119-8 · Cited by 414

The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals

Eberhart, D. (1996) · Human Molecular Genetics · doi:10.1093/hmg/5.8.1083 · Cited by 390

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

Schenck, A., Bardoni, B., Moro, A., Bagni, C., & Mandel, J.-L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.151231598 · Cited by 356

The fragile X mental retardation protein is associated with ribosomes

Khandjian, E. W., Corbin, F., Woerly, S., & Rousseau, F. (1996) · Nature Genetics · doi:10.1038/ng0196-91 · Cited by 251

Map1b Is Required for Axon Guidance and Is Involved in the Development of the Central and Peripheral Nervous System

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Purified Recombinant Fmrp Exhibits Selective RNA Binding as an Intrinsic Property of the Fragile X Mental Retardation Protein

Brown, V., Small, K. M., Lakkis, L., Feng, Y., Gunter, C., Wilkinson, K. D., & Warren, S. T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.25.15521 · Cited by 192

Isolation of an FMRP-Associated Messenger Ribonucleoprotein Particle and Identification of Nucleolin and the Fragile X-Related Proteins as Components of the Complex

Ceman, S., Brown, V., & Warren, S. T. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.12.7925 · Cited by 181

Neuronal abnormalities in microtubule-associated protein 1B mutant mice.

Edelmann, W., Zervas, M., Costello, P. S., Roback, L., Fischer, I., Hammarback, J. A., Cowan, N. J., Davies, P., Wainer, B. H., & Kucherlapati, R. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.3.1270 · Cited by 149

Tightly regulated, developmentally specific expression of the first open reading frame from LINE-1 during mouse embryogenesis.

Trelogan, S., & Martin, S. L. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.5.1520 · Cited by 144

A novel RNA binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein

Bardoni, B., Schenck, A., & Louis Mandel, J. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.13.2557 · Cited by 136

A nuclear role for the Fragile X mental retardation protein.

Fridell, R. A., Benson, R. E., Hua, J., Bogerd, H. P., & Cullen, B. R. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00924.x · Cited by 131

Delayed Development of Nervous System in Mice Homozygous for Disrupted Microtubule-associated Protein 1B (MAP1B) Gene

Takei, Y., Kondo, S., Harada, A., Inomata, S., Noda, T., & Hirokawa, N. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.7.1615 · Cited by 123

In vitro selection of RNA ligands for the ribosomal L22 protein associated with Epstein-Barr virus-expressed RNA by using randomized and cDNA-derived RNA libraries

Dobbelstein, M., & Shenk, T. E. (1995) · Journal of Virology · doi:10.1128/jvi.69.12.8027-8034.1995 · Cited by 96

A guanosine quadruplex and two stable hairpins flank a major cleavage site in insulin-like growth factor II mRNA

Christiansen, J., Kofod, M., & Nielsen, F. C. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.25.5709 · Cited by 85

RNAs That Interact with the Fragile X Syndrome RNA Binding Protein FMRP

Sung, Y. J., Conti, J., Currie, J. R., Brown, W. T., & Denman, R. B. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3405 · Cited by 82

Identification of Mouse YB1/p50 as a Component of the FMRP-Associated mRNP Particle

Ceman, S., Nelson, R., & Warren, S. T. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.4035 · Cited by 81

Nitrocellulose Filter Binding for Determination of Dissociation Constants

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Composite of A and F-type 5′ terminal sequences defines a subfamily of mouse LINE-1 elements

Adey, N. B., Schichman, S. A., Hutchison, C. A., & Edgell, M. H. (1991) · Journal of Molecular Biology · doi:10.1016/0022-2836(91)80057-2 · Cited by 19

Untitled work

Irwin (2001) · doi:10.1002/1096-8628(20010115)98:2

Human MicroRNA Targets

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The mGluR theory of fragile X mental retardation

Bear, M. F., Huber, K. M., & Warren, S. T. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.04.009 · Cited by 1,580

SELEX—A (r)evolutionary method to generate high-affinity nucleic acid ligands

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Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective

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Small regulatory RNAs in mammals

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Identification of FMRP‐associated mRNAs using yeast three‐hybrid system

Zou, K., Liu, J., Zhu, N., Lin, J., Liang, Q., Brown, W. T., Shen, Y., & Zhong, N. A. (2007) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30678 · Cited by 17

Transcriptome‐wide Identification of the mRNA target sites of the Fragile‐X Mental Retardation Proteins

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Twin-track approach to fragile X

Patterson, M. N. (2002) · Nature Reviews Genetics · doi:10.1038/nrg719

Identification of Messenger RNAs and MicroRNAs Associated With Fragile X Mental Retardation Protein

Duan, R., & Jin, P. (2006) · Humana Press eBooks · doi:10.1385/1-59745-123-1:267 · Cited by 22

Bioinformatic Prediction of mRNA Targets of the Fragile X Mental

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