The DOI matches its Crossref record, with a small difference in title or year; 93 of the 97 references it cites were found in a registry or an index; 1 of the 49 sources its claims cite were checked for support.
Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults
Open accessAbstract
Background The relationship of health risk behavior and disease in adulthood to the breadth of exposure to childhood emotional, physical, or sexual abuse, and household dysfunction during childhood has not previously been described. Methods A questionnaire about adverse childhood experiences was mailed to 13,494 adults who had completed a standardized medical evaluation at a large HMO; 9,508 (70.5%) responded. Seven categories of adverse childhood experiences were studied: psychological, physical, or sexual abuse; violence against mother; or living with household members who were substance abusers, mentally ill or suicidal, or ever imprisoned. The number of categories of these adverse childhood experiences was then compared to measures of adult risk behavior, health status, and disease. Logistic regression was used to adjust for effects of demographic factors on the association between the cumulative number of categories of childhood exposures (range: 0-7) and risk factors for the leading causes of death in adult life. Results More than half of respondents reported at least one, and one-fourth reported > or = 2 categories of childhood exposures. We found a graded relationship between the number of categories of childhood exposure and each of the adult health risk behaviors and diseases that were studied (P or = 50 sexual intercourse partners, and sexually transmitted disease; and 1.4- to 1.6-fold increase in physical inactivity and severe obesity. The number of categories of…
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Claims the paper makes
50 Own result · 12 No full text of the sources · 12 Own interpretation · 10 Own method · 5 Not checked yet · 1 Partly supported · 1 Sources not found · accuracy not yet measured
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In the paper
“Longitudinal follow-up of adults whose childhood abuse was well documented has shown that their retrospective reports of childhood abuse are likely to under-estimate actual occurrence.47,48”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
What the sources say
- Partly supportedcites [47] Femina, 1990, Child abuse, Child Abuse Negl sourceExperimental — accuracy not yet measured
The Results report that eight adults with well-documented abuse in their adolescent records denied it at follow-up, and the Discussion says retrospective inaccuracies in this sample were in the direction of under-reporting. The paper limits that finding to a small sample of former delinquents and says its generalizability is uncertain; the claim does not retain that population qualifier. (LLM, conf=0.82)
- Not checked — no full text of the sourcecites [48] Williams, 1995, Recovered memories of abuse in women with documented child sexual victimization histories, J Traumatic Stress source
hedgedstates an association- Asserted: passes — The authors put it forward as true.
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- Partly supported
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“More than half of respondents reported at least one, and one-fourth reported Ն2 categories of childhood exposures.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
plain- Asserted: passes — The authors put it forward as true.
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In the paper
“There was no statistically significant dose-response relationship for a history of stroke or diabetes.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Significance of Dose-Response Relationships
plain- Asserted: passes — The authors put it forward as true.
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In the paper
“we found a strong, dose-response relationship between the number of childhood exposures and each of the 10 risk factors for the leading causes of death that we studied (P Ͻ .001).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Significance of Dose-Response Relationships
boostedstates an association- Asserted: passes — The authors put it forward as true.
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In the paper
“The seven categories of adverse childhood experiences were strongly interrelated and persons with multiple categories of childhood exposure were likely to have multiple health risk factors later in life.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
hedgedstates an association- Asserted: passes — The authors put it forward as true.
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In the paper
“More than half of respondents reported at least one, and one-fourth reported Ն2 categories of childhood exposures.”
- Also stated in: § Adverse Childhood Exposures · plain
“More than half of respondents (52%) experienced Ն1 category of adverse childhood exposure; 6.2% reported Ն4 exposures.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
plain- Asserted: passes — The authors put it forward as true.
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- Also stated in: § Adverse Childhood Exposures · plain
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“and a 1.4-to 1.6-fold increase in physical inactivity and severe obesity.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
plainstates an association- Asserted: passes — The authors put it forward as true.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The seven categories of adverse childhood experiences were strongly interrelated and persons with multiple categories of childhood exposure were likely to have multiple health risk factors later in life.”
- Also stated in: § Relationships between Categories of Childhood Exposure · plain
“The relationship between single categories of exposure was significant for all comparisons (P Ͻ .001;chi-square).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
boostedstates an association- Asserted: passes — The authors put it forward as true.
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- Also stated in: § Relationships between Categories of Childhood Exposure · plain
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The number of categories of adverse childhood exposures showed a graded relationship to the presence of adult diseases including ischemic heart disease, cancer, chronic lung disease, skeletal fractures, and liver disease.”
- Also stated in: § Discussion · plain
“Disease conditions including ischemic heart disease, cancer, chronic lung disease, skeletal fractures, and liver disease, as well as poor self-rated health also showed a graded relationship to the breadth of childhood exposures.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
plainstates an association- Asserted: passes — The authors put it forward as true.
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- Also stated in: § Discussion · plain
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“We also found a significant (P Ͻ .05)dose-response relationship between the number of childhood exposures and the following disease conditions: ischemic heart disease, cancer, chronic bronchitis or emphysema, history of hepatitis or jaundice, skeletal fractures, and poor self-rated health.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Significance of Dose-Response Relationships
plainstates an association- Asserted: passes — The authors put it forward as true.
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- It may state two separate claims as one. 16
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“a 2-to 4-fold increase in smoking, poor self-rated health, Ն50 sexual intercourse partners, and sexually transmitted disease;”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
plainstates an association- Asserted: passes — The authors put it forward as true.
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In the paper
“For example, among persons with no childhood exposures, 56% had none of the 10 risk factors whereas only 14% of persons with Ն4 categories of childhood exposure had no risk factors.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Childhood Exposures and Clustering of Health Risk Factors
plainstates an association- Asserted: passes — The authors put it forward as true.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The most prevalent of the 7 categories of childhood exposure was substance abuse in the household (25.6%); the least prevalent exposure category was evidence of criminal behavior in the household (3.4%).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Adverse Childhood Exposures
plain- Asserted: passes — The authors put it forward as true.
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It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“By contrast, only 1% of persons with no childhood exposures had four or more risk factors, whereas 7% of persons with Ն4 childhood exposures had four or more risk factors (Table 6).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Childhood Exposures and Clustering of Health Risk Factors
plainstates an association- Asserted: passes — The authors put it forward as true.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“| Mental illness | | 18.8 |”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
plain- Asserted: passes — The authors put it forward as true.
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In the paper
“| Ն65 | 2,610 | 60.0 | 24.5 | 8.9 | 4.2 | 2.4 |”
- Also stated in: § Discussion · plain
“| 19-34 | 807 | 35.4 | 25.4 | 17.2 | 11.0 | 10.9 |”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
plainstates an association- Asserted: passes — The authors put it forward as true.
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- Also stated in: § Discussion · plain
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“| Psychological | | 11.1 |”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
plain- Asserted: passes — The authors put it forward as true.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“| Mother treated violently | | 12.5 |”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
plain- Asserted: passes — The authors put it forward as true.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“| 0 | 3,861 | 56 | 29 | 10 | 4 | 1 |”
- Also stated in: § Discussion · plain
“| Ն4 | 545 | 14 | 26 | 28 | 17 | 7 |”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
plainstates an association- Asserted: passes — The authors put it forward as true.
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- Rests on an assumption: The number of categories of adverse childhood exposure is a valid cumulative measure of adversity.
- Also stated in: § Discussion · plain
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Similarly, the odds ratios for skeletal fractures, hepatitis or jaundice, and poor self-rated health were 1.6, 2.3, and 2.2, respectively (Table 8).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Relationship between Childhood Exposures and Disease Conditions
plainstates an association- Asserted: passes — The authors put it forward as true.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“| Substance abuse | | 25.6 |”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
plain- Asserted: passes — The authors put it forward as true.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The relationship between single categories of exposure was significant for all comparisons (P Ͻ .001;chi-square).For persons reporting any single category of exposure, the probability of exposure to any additional category ranged from 65%-93% (median: 80%); similarly, the probability of Ն2 additional exposures ranged from 40%-74% (median: 54.5%).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Relationships between Categories of Childhood Exposure
plainstates an association- Asserted: passes — The authors put it forward as true.
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A result the paper states — it cites no source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Because adverse childhood experiences are common and they have strong long-term associations with adult health risk behaviors, health status, and diseases, increased attention to primary, secondary, and tertiary prevention strategies is needed.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
boostedstates an association- Asserted: passes — The authors put it forward as true.
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What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Respondent (n ϭ 9,508) and nonrespondent (n ϭ 3,986) groups were similar in their percentages of women (53.7% and 51.0%, respectively) and in their mean years of education (14.0 years and 13.6 years, respectively).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Comparison of Respondents and Nonrespondents
plain- Asserted: passes — The authors put it forward as true.
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What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“After second mailings of the questionnaire to persons who did not respond to the first mailing, the response rate for the survey was 70.5% (9,508/13,494).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Survey Methods
plain- Asserted: passes — The authors put it forward as true.
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In the paper
“Respondents were slightly more likely to answer affirmatively than nonrespondents (6.1% vs. 5.4%, respectively).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Comparison of Respondents and Nonrespondents
plainstates an association- Asserted: passes — The authors put it forward as true.
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A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Without measuring these household factors as well, long-term influence might be wrongly attributed solely to single types of abuse and the cumulative influence of multiple categories of adverse childhood experiences would not be assessed.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
hedgedstates a possible cause- Asserted: passes — The authors put it forward as true.
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- Rests on an assumption: Conditions such as drug abuse, spousal violence, and criminal activity in the household may co-occur with specific forms of abuse that involve children.
None of the sources cited for this claim have been checked yet.
In the paper
“We used questions from published surveys to construct the ACE Study questionnaire.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Questionnaire Design
What the sources say
- Not checked — no full text of the sourcecites [39] Straus, 1990 source
- Not checked — no full text of the sourcecites [40] Wyatt, 1985, The sexual abuse of Afro-American and White-American women in childhood, Child Abuse Negl source
- Not checked yetcites [41] National Center for Health Statistics. Exposure to alcoholism in the family: United States, 1988. Advance Data, No. 205. U.S. Department of Health and Human Services, Washington, DC; September 30, 1991.
plain- Asserted: passes — The authors put it forward as true.
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What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Respondents were older than nonrespondents (means 56.1 years and 49.3 years) and more likely to be white (83.9% vs. 75.3%)although the actual magnitude of the differences was small.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Comparison of Respondents and Nonrespondents
plainstates an association- Asserted: passes — The authors put it forward as true.
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A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“Studies of the long-term effects of childhood abuse have usually examined single types of abuse, particularly sexual abuse, and few have assessed the impact of more than one type of abuse.5,24 -28”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
What the sources say
- Not checked — no full text of the sourcecites [5] McCauley, 1997, Clinical characteristics of women with a history of childhood abuse, JAMA source
- Not checked — no full text of the sourcecites [24] Briere, 1988, Multivariate correlates of childhood psychological and physical maltreatment among university women, Child Abuse Negl source
- Not checked — no full text of the sourcecites [25] Briere, 1990, Differential adult symptomatology associated with three types of child abuse histories, Child Abuse Negl source
- Not checked — no full text of the sourcecites [26] Claussen, 1991, Physical and psychological maltreatment, Child Abuse Negl source
- Not checked — no full text of the sourcecites [27] Moeller, 1993, The combined effects of physical, sexual, and emotional abuse during childhood, Child Abuse Negl source
- Not checked — no full text of the sourcecites [28] Bryant, 1995, Suicidality in college women who were sexually and physically punished by parents, Violence Vict source
plain- Asserted: passes — The authors put it forward as true.
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What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Respondents and nonrespondents did not differ with regard to their self-rated health, smoking, other substance abuse, or the presence of common medical conditions such as a history of heart attack or stroke, chronic obstructive lung disease, hypertension, or diabetes, or with regard to marital status or current family, marital, or job-related problems (data not shown).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Comparison of Respondents and Nonrespondents
plain- Asserted: passes — The authors put it forward as true.
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In the paper
“For example, the American Medical Association recommends screening of women for exposure to violence at every entrance to the health system; 66 however, such screening appears to be rare.67”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
What the sources say
- Not checked yetcites [66] 1992, American Medical Association Diagnostic and Treatment Guidelines on Domestic Violence, Arch Fam Med
plain- Asserted: passes — The authors put it forward as true.
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A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In addition, there may be mediators of the relationship between childhood experiences and adult health status other than the risk factors we examined.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
hedgedstates a possible cause- Asserted: passes — The authors put it forward as true.
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A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“High levels of exposure to adverse childhood experiences would expectedly produce anxiety, anger, and depression in children.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
hedgedstates a possible cause- Asserted: passes — The authors put it forward as true.
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Probably not a substantial claim. The paper may give no reason why it holds.
In the paper
“Although articles in the general medical literature are alerting the medical community to the fact that childhood abuse is common, 59 adolescent health care is often inadequate in terms of psychosocial assessment and anticipatory guidance.60”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
What the sources say
- Not checked — no full text of the sourcecites [60] Rixey, 1994, Family violence and the adolescent, Maryland Med J
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
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- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“For example, nicotine is recognized as having beneficial psychoactive effects in terms of regulating affect 49 and persons who are depressed are more likely to smoke.50,51”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
What the sources say
- Not checked — no full text of the sourcecites [49] Carmody, 1989, Affect regulation, nicotine addiction, and smoking cessation, J Psychoactive Drugs source
- Not checked — no full text of the sourcecites [50] Anda, 1990, Depression and the dynamics of smoking. A national perspective, JAMA source
- Not checked — no full text of the sourcecites [51] Glassman, 1990, Smoking, smoking cessation, and major depression, JAMA source
plainstates an association- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“To the degree that behaviors such as smoking, alcohol, or drug use are found to be effective as coping devices, they would tend to be used chronically.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
hedgedstates a possible cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
In the paper
“Many physicians may fear that discussions of sexual violence and other sensitive issues are too personal even for the doctor-patient relationship.65”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
What the sources say
- Not checked — no full text of the sourcecites [65] Sugg, 1992, Primary care physicians’ response to domestic violence. Opening Pandora’s box, JAMA source
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“because it is strongly predictive of mortality.45”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > 3.4 Any category reported 52.1%
What the sources say
- Not checked — no full text of the sourcecites [45] Idler, 1990, Self-rated health and mortality in the NHANES I Epidemiologic Follow-up Study, Am J Pub Health source
boostedstates an association- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Second, some persons with health risk behaviors or diseases may have been either more, or less, likely to report adverse childhood experiences.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
hedgedstates a possible cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
None of the sources cited for this claim have been checked yet.
In the paper
“Moreover, these childhood exposures include emotionally sensitive topics such as family alcoholism 29,30 and sexual abuse.64”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
What the sources say
- Not checked — no full text of the sourcecites [29] Zeitlen, 1994, Children with alcohol misusing parents, Br Med Bull source
- Not checked — no full text of the sourcecites [30] Dore, 1995, Identifying substance abuse in maltreating families, Child Abuse Negl source
- Not checked yetcites [64] Tabachnick, 1997, Perceptions of child sexual abuse as a public health problem. Vermont, September 1995, Morb Mortal Wkly Rep
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
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- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Furthermore, disease conditions could be either over-or under-reported by patients when they complete the medical questionnaire.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The relationship between childhood experiences and adult health status is likely to be overlooked in medical practice because the time delay between exposure during childhood and recognition of health problems in adult medical practice is lengthy.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
hedgedstates a possible cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The data about adverse childhood experiences are based on self-report, retrospective, and can only demonstrate associations between childhood exposures and health risk behaviors, health status, and diseases in adulthood.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
plainstates an association- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Thus, smoking, which is medically and socially viewed as a “problem” may, from the perspective of the user, represent an effective immediate solution that leads to chronic use.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
hedgedstates a possible cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
In the paper
“Although articles in the general medical literature are alerting the medical community to the fact that childhood abuse is common, 59 adolescent health care is often inadequate in terms of psychosocial assessment and anticipatory guidance.60”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
What the sources say
- Not checked — no full text of the sourcecites [59] MacMillan, 1997, Prevalence of child physical and sexual abuse in the community. Results from the Ontario Health Supplement, JAMA source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Logistic regression analysis was employed to adjust for the potential confounding effects of age, sex, race, and educational attainment on the relationship between the number of childhood exposures and health problems.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Statistical Analysis
plainstates an association- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
The paper relies on this without support.
Conditions such as drug abuse, spousal violence, and criminal activity in the household may co-occur with specific forms of abuse that involve children.
“Conditions such as drug abuse, spousal violence, and criminal activity in the household may co-occur with specific forms of abuse that involve children.”
The paper relies on this without support.
The number of categories of adverse childhood exposure is a valid cumulative measure of adversity.
“Number of categories of adverse childhood exposure and the adjusted odds of risk factors including current smoking, severe obesity, physical inactivity, depressed mood, and suicide attempt”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Adverse childhood experiences (ACEs) were documented at baseline using the 10-item ACE Study questionnaire to measure childhood trauma, and were grouped as either “0–3” or “4+” due to the high rate of chronic health problems among individuals with scores of 4 or more 37.”
From Effects of a trauma-informed mindful recovery program on comorbid pain, anxiety, and substance use during primary care buprenorphine treatment: A proof-of-concept study (2023) · cites this paper as [37]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Both exposure to IPV and parental separation or divorce are two adverse childhood experiences (ACEs) that are linked in a dose–response relationship to adverse health consequences through the lifespan (Felitti et al., 1998).”
From Post‐separation abuse: A concept analysis (2023) · cites this paper as Felitti et al., 1998
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“There is a strong, graded link between exposure to childhood adversity and risk of negative health, social, and emotional outcomes, including several major categories of chronic disease, lung cancer, various autoimmune diseases, depression and other mental illnesses, and high-risk behaviors (e.g., Felitti et al., 1998).”
From Malleability, plasticity, and individuality: How children learn and develop in context1 (2019) · cites this paper as Felitti et al., 1998
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“on average, the life span of individuals with six or more ACEs is 20 years shorter than that of those with zero ACEs (Felitti et al., 1998).”
From Malleability, plasticity, and individuality: How children learn and develop in context1 (2019) · cites this paper as Felitti et al., 1998
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“while adults with ELS/CT experience could be at increased risk of disease with potentially immune origin (36, 53).”
From Developmental Trajectories of Early Life Stress and Trauma: A Narrative Review on Neurobiological Aspects Beyond Stress System Dysregulation (2019) · cites this paper as [53]
Experimental — accuracy not yet measured
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In one study of more than 9,500 adults, for example, exposure to multiple forms of early life stress was associated with a 4.6-fold increase in risk of being depressed over the past year (Felitti et al., 1998).”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Felitti et al., 1998
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Children enter foster care with a sum of adverse childhood experiences.55–57”
From Caregiving disruptions affect growth and pubertal development in early adolescence in institutionalized and fostered Romanian children: A randomized clinical trial (2018) · cites this paper as [55]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Adverse childhood experiences, including growing up in a context of maternal substance use (74), predicts an earlier age of onset for alcohol (62, 75) and other drug use (76, 77), and increased odds for attempting suicide (78).”
From Mothering, Substance Use Disorders and Intergenerational Trauma Transmission: An Attachment-Based Perspective (2019) · cites this paper as [74]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Outcomes associated with early adversity include higher risk of type 2 diabetes, obesity, ischemic heart disease, cancers, depression, addictions, and premature mortality, as well as social outcomes including unemployment and lower educational attainment [1–8].”
From Biological embedding of childhood adversity: from physiological mechanisms to clinical implications (2017) · cites this paper as [1]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Epidemiological studies have demonstrated that adverse childhood experiences, namely exposures such as neglect, abuse, caregiver mental illness, and family or community violence, predict poorer long-term outcomes across health and social domains.”
From Biological embedding of childhood adversity: from physiological mechanisms to clinical implications (2017) · cites this paper as [1]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Interest in metabolic embedding of ELA stems from epidemiological [1, 69] and clinical [70] studies linking ELA to obesity, dyslipidemia, and type 2 diabetes, raising questions about possible causal pathways.”
From Biological embedding of childhood adversity: from physiological mechanisms to clinical implications (2017) · cites this paper as [1]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Adverse psychosocial exposures in early life, namely experiences such as child maltreatment, caregiver stress or depression, and domestic or community violence, have been associated in epidemiological studies with increased lifetime risk of adverse outcomes, including diabetes, heart disease, cancers, and psychiatric illnesses.”
From Biological embedding of childhood adversity: from physiological mechanisms to clinical implications (2017) · cites this paper as [1]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In full, ELA-induced changes may mediate epidemiological links to key diseases, including, among others, obesity, dyslipidemia, type 2 diabetes, atherosclerosis, asthma, thromboembolic events (myocardial infarction, stroke), cancer onset and progression, as well as addictions, psychopathology, and adverse social outcomes [1–6, 18].”
From Biological embedding of childhood adversity: from physiological mechanisms to clinical implications (2017) · cites this paper as [1]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“These frequencies are consistent with previous studies documenting elevated rates of childhood adversity among individuals with SUD [3, 5, 9].”
From The link of adverse childhood experiences and attachment to maladaptive personality traits in adults diagnosed with substance use disorder (2025) · cites this paper as [3]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Adverse childhood experiences are associated with many negative adult health and health care utilisation outcomes, including cardiovascular illness, depression, suicide attempts, unhealthy substance use, obesity, lung disease, liver disease, cancer and medically unexplained symptoms such as pain or gastrointestinal problems[1–6].”
From Health care utilisation changes among Alaska Native adults after participation in an indigenous community programme to address adverse life experiences: a propensity score-matched analysis (2020) · cites this paper as [3]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Dose-response relationships between adverse childhood experiences (ACEs) and multiple risk factors have been documented among AIANs and non-AIANs [51,70].”
From Substance and Behavioral Addictions among American Indian and Alaska Native Populations (2022) · cites this paper as [70]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Rather, the overwhelming majority of studies14 have employed an empirical specification similar to that which has predominated in the literature on childhood adversity, i.e., a sum score of exposures.15–18”
From Co-occurring epidemics, syndemics, and population health (2017) · cites this paper as [17]
The cited source says what the claim attributes to it.
In the citing paper
“Much research associates CT with adverse physical and mental health outcomes (1,2)”
From Impact of Childhood Trauma on Executive Function in Adolescence—Mediating Functional Brain Networks and Prediction of High-Risk Drinking (2020) · cites this paper as [1]
The cited source says what the claim attributes to it.
In the citing paper
“Moreover, there is commonly a dose-response relationship between the number of types of adversity associated and the magnitude of the risk for depression.4-11”
From Early life adversity and the epigenetic programming of hypothalamic-pituitary-adrenal function (2014) · cites this paper as [4]
The cited source says what the claim attributes to it.
In the citing paper
“Similarly, the original ACE study [3] demonstrated that individuals exposed to multiple adverse experiences had a four- to twelve-fold increased risk for alcoholism, drug abuse, depression, and suicide attempts.”
From The link of adverse childhood experiences and attachment to maladaptive personality traits in adults diagnosed with substance use disorder (2025) · cites this paper as [3]
The cited source says what the claim attributes to it.
In the citing paper
“Exposure to ELA is associated with a clustering of health risks, with increasing exposure related to an increasing number of HRBs.32”
From Early life adversity and health-risk behaviors: Proposed psychological and neural mechanisms (2018) · cites this paper as [32]
The cited source says what the claim attributes to it.
In the citing paper
“Such an approach facilitates the synthesis of complex evidence for application, and is supported by observed dose–response effects linking cumulative early adversity to later outcomes [1, 3, 5], and by the “allostatic load” paradigm exploring pathogenic effects of cumulative all-cause stress [15].”
From Biological embedding of childhood adversity: from physiological mechanisms to clinical implications (2017) · cites this paper as [1]
The cited source says what the claim attributes to it.
In the citing paper
“Dose-response relationship between number of adversities and health and social effects are observed in large epidemiological studies”
From Biological embedding of childhood adversity: from physiological mechanisms to clinical implications (2017) · cites this paper as [1]
The cited source says what the claim attributes to it.
In the citing paper
“Adverse childhood experiences (ACEs) considerably increase the likelihood of mental illness, health risk behaviors, and chronic physical illnesses.”
From The link of adverse childhood experiences and attachment to maladaptive personality traits in adults diagnosed with substance use disorder (2025) · cites this paper as [3]
The cited source says what the claim attributes to it.
In the citing paper
“These findings are consistent with research that has supported the relationship between ACEs and further negative health consequences in the general population (Buckingham & Daniolos, 2013;Cicchetti & Handley, 2019;Felitti et al., 1998;Hughes et al., 2017).”
From Adverse childhood experiences (ACEs) and substance use disorder (SUD): A scoping review (2021) · cites this paper as Felitti et al., 1998
In the citing paper
“Also, adults who were abused as children have been shown to be at increased risk of disease with potential inflammatory origin (9, 10).”
From Childhood maltreatment predicts adult inflammation in a life-course study (2007) · cites this paper as [9]
In the citing paper
“Inflammation may be an important developmental mediator linking adverse experiences in early life to poor adult health.”
From Childhood maltreatment predicts adult inflammation in a life-course study (2007) · cites this paper as [9]
In the citing paper
“Given that the effect of stress often appears to be cumulative (2, 9, 19), we derived a cumulative exposure index for each child by counting the number of maltreatment experiences during the first decade of life (31);”
From Childhood maltreatment predicts adult inflammation in a life-course study (2007) · cites this paper as [9]
In the citing paper
“Childhood adversity has been repeatedly and robustly linked to physical and mental illness across the lifespan.”
From Developmental psychoneuroendocrine and psychoneuroimmune pathways from childhood adversity to disease (2017) · cites this paper as Felitti et al., 1998
In the citing paper
“The first study using the DAWBA-RAD section reported a very high RAD point-prevalence of 63.0% (96/153) in a sample of looked after youth in a variety of placement forms [29].”
From Mental disorders in foster children: a study of prevalence, comorbidity and risk factors (2013) · cites this paper as [29]
In the citing paper
“Compared to another study on RAD using DAWBA in high-risk foster youths [29], our estimate was quite moderate.”
From Mental disorders in foster children: a study of prevalence, comorbidity and risk factors (2013) · cites this paper as [29]
In the citing paper
“Victims of childhood physical or sexual abuse or parental neglect are at considerably greater risk for affective disorders.1-4”
From Early life adversity and the epigenetic programming of hypothalamic-pituitary-adrenal function (2014) · cites this paper as [4]
In the citing paper
“Epidemiological studies provide compelling support for the association between cumulative, adverse childhood experiences and the risk for depression.4,5”
From Early life adversity and the epigenetic programming of hypothalamic-pituitary-adrenal function (2014) · cites this paper as [4]
In the citing paper
“In humans, various forms of ELA are associated with illicit drug use later in life [21,22,23].”
From Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications (2020) · cites this paper as [21]
In the citing paper
“In addition, there are established links between ELA and obesity [21,24], however, the exact mechanisms are not understood.”
From Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications (2020) · cites this paper as [21]
In the citing paper
“Strong links between ACEs and the initiation of opioid use have been described (72, 73).”
From A Biopsychosocial Overview of the Opioid Crisis: Considering Nutrition and Gastrointestinal Health (2019) · cites this paper as [72]
In the citing paper
“The Adverse Childhood Experiences (ACE) study from 1998 highlighted 5- to 10-fold increase in the risk of AUD and SUD following exposure to four or more ACEs in the first 18 years of life [112].”
From Separating the Signal from the Noise: How Psychiatric Diagnoses Can Help Discern Food Addiction from Dietary Restraint (2020) · cites this paper as [112]
In the citing paper
“Indeed, ELA is associated with a greater likelihood of smoking cigarettes,32,43,44 abusing alcohol and drugs,32,45–47 eating a poor diet,48 and being obese.32,49”
From Early life adversity and health-risk behaviors: Proposed psychological and neural mechanisms (2018) · cites this paper as [32]
In the citing paper
“ELA has also been associated with physical inactivity, which likely also contributes to the link between ELA and obesity.32”
From Early life adversity and health-risk behaviors: Proposed psychological and neural mechanisms (2018) · cites this paper as [32]
In the citing paper
“Research has consistently found that care leavers are more likely to have experienced high levels of adverse childhood experience (ACEs) and are at significantly greater risk for negative outcomes (Felitti et al., 1998; Simkiss, 2019).”
From The relationship between spirituality and resilience and well-being: a study of 529 care leavers from 11 nations. (2023) · cites this paper as Felitti et al., 1998
In the citing paper
“The documented risks of having care experience are substantial and varied (Berlin et al., 2011; Felitti et al., 1998; Simkiss, 2019).”
From The relationship between spirituality and resilience and well-being: a study of 529 care leavers from 11 nations. (2023) · cites this paper as Felitti et al., 1998
In the citing paper
“Early life physical and sexual abuse carry with it a life-long burden of behavioral and pathophysiological problems (Felitti et al., 1998; Heim and Nemeroff, 2001).”
From Central effects of stress hormones in health and disease: understanding the protective and damaging effects of stress and stress mediators (2008) · cites this paper as Felitti et al., 1998
In the citing paper
“There are enormous individual differences in the response to stress, based upon the experience of the individual early in life and in adult life.”
From Protective and damaging effects of stress mediators: central role of the brain (2006) · cites this paper as [41]
In the citing paper
“Early life physical and sexual abuse imposes a life- long burden of behavioral and pathophysiological problems.41,42”
From Protective and damaging effects of stress mediators: central role of the brain (2006) · cites this paper as [41]
In the citing paper
“Early-life events related to maternal care in animals, as well as parental care in humans, play a powerful role in later mental and physical health, as demonstrated by the adverse childhood experiences (ACE) studies”
From Neurobiological and Systemic Effects of Chronic Stress (2017) · cites this paper as [77]
In the citing paper
“ACE have a disproportionately powerful effect on life long trajectories of health and disease, 68 and poverty contributes in its own way as well as creating circumstances for ACE, 114 which, however, occurs across all levels of socioeconomic status (SES).”
From Neurobiological and Systemic Effects of Chronic Stress (2017) · cites this paper as [77]
In the citing paper
“Boarding schools as a form of cultural genocide and source of historical trauma have had a variety of negative health impacts on Native people, such as high suicide rates, post-traumatic stress disorder, and other illnesses such as heart disease and diabetes that are connected to trauma (Brave Heart et al. 2011;Duran 2019;Felitti et al. 1998).”
From Archaeology and Social Justice in Native America (2022) · cites this paper as Felitti et al. 1998
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Rated major: it would touch a result — a value a result rests on, reported and recomputed p-values on opposite sides of the significance level, two passages that conflict with no sign which is right, or a cited work retracted before this paper was published.
In the paper
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
“We found a graded relationship between the number of categories of childhood exposure and each of the adult health risk behaviors and diseases that were studied (P Ͻ .001).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Significance of Dose-Response Relationships
“There was no statistically significant dose-response relationship for a history of stroke or diabetes.”
Rated minor: it would not touch a result — a value no result rests on, a p-value that stays on the same side of the significance level, or a conflict that is clerical, resolved elsewhere in the paper, or outside its own findings.
In the paper
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Exclusions from Analysis
“The mean age of the 8,506 persons included in this analysis was 56.1 years”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Exclusions from Analysis
“After these exclusions, 8,056 of the original 9,508 survey respondents (59.7% of the original sample of 13,494) remained and were included in the analysis.”
Rated minor: it would not touch a result — a value no result rests on, a p-value that stays on the same side of the significance level, or a conflict that is clerical, resolved elsewhere in the paper, or outside its own findings.
In the paper
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Abstract
“a 1.4-to 1.6-fold increase in physical inactivity and severe obesity.”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
“| | 4 or more | 523 | 26.6 | 1.3 | ( 1.1-1.6) |”
Rated minor: it would not touch a result — a value no result rests on, a p-value that stays on the same side of the significance level, or a conflict that is clerical, resolved elsewhere in the paper, or outside its own findings.
In the paper
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Relationship between Childhood Exposures and Disease Conditions
“Similarly, the odds ratios for skeletal fractures, hepatitis or jaundice, and poor self-rated health were 1.6, 2.3, and 2.2, respectively (Table 8).”
§ Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults The Adverse Childhood Experiences (ACE) Study > Discussion
“| | 4 or more | 543 | 10.7 | 2.4 | (1.8-3.3) |”
Citations
Cites
Child abuse: Adolescent records vs. adult recall
Femina, D. D., Yeager, C. A., & Lewis, D. O. (1990) · Child Abuse & Neglect · doi:10.1016/0145-2134(90)90033-p · Cited by 8,820
Mail and Telephone Surveys: The Total Design Method.
Babbie, E. R., & Dillman, D. A. (1982) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2068433 · Cited by 6,859
Physical Activity and Health: A Report of the Surgeon General
(1995) · PsycEXTRA Dataset · doi:10.1037/e525162010-001 · Cited by 5,488
Actual causes of death in the United States
McGinnis, J. M. (1993) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1993.03510180077038 · Cited by 5,480
Robins, L. N. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780290015001 · Cited by 5,219
The traumatic impact of child sexual abuse: A conceptualization.
Finkelhor, D., & Browne, A. (1985) · American Journal of Orthopsychiatry · doi:10.1111/j.1939-0025.1985.tb02703.x · Cited by 1,891
Finkelhor, D., Hotaling, G., Lewis, I. A., & Smith, C. (1990) · Child Abuse & Neglect · doi:10.1016/0145-2134(90)90077-7 · Cited by 1,754 · cited 1×
“A national telephone survey of adults in 1990 using similar criteria for sexual abuse estimated that 27% of women and 16% of men had been sexually abused.(12) There are several reasons to believe that our estimates of the long-term relationship between adverse childhood experiences and adult health are conservative.”
MethodPhysical Violence in American Families: Risk Factors and Adaptations to Violence in 8,145 Families.
Goetting, A., Straus, M. A., & Gelles, R. J. (1990) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2073234 · Cited by 1,670
Societal change and change in family violence from 1975 to 1985 as revealed by two national surveys
Straus, M. A., & Gelles, R. J. (1986) · Journal of Marriage and the Family · doi:10.2307/352033 · Cited by 1,592
Book Review: Mail and Telephone Surveys
Harris, L. M., & Dillman, D. A. (1979) · Journal of Marketing Research · doi:10.2307/3150885 · Cited by 1,431
Research works printed but not linked: 2
- 1996, Morb Mortal Wkly Rep, 45, 161
- SAS Procedures Guide. SAS Institute Inc. Version 6, 3rd edition, Cary, NC: SAS Institute; 1990.
Cited by
Sorted by citations
Items 7,201–7,300 of 18,888
Feasibility and acceptability study of the online ACT-Raising Safe Kids program
Lotto, C. R., Altafim, E. R. P., & Linhares, M. B. M. (2022) · Children and Youth Services Review · doi:10.1016/j.childyouth.2022.106591 · Cited by 14
Sosnowski, D. W., Rojo‐Wissar, D. M., Smail, E. J., Musci, R. J., Wilcox, H. C., & Johnson, S. B. (2022) · Emerging Adulthood · doi:10.1177/21676968221114260 · Cited by 14
“For example, much of the ACE literature has relied on 10 experiences [originally defined by Felitti et al. (1998)] – occurring prior to age 18 – and tested associations with outcomes using the cumulative risk framework.”
BackgroundAfifi, T. O., Salmon, S., Stewart-Tufescu, A., & Taillieu, T. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191710580 · Cited by 16
“ACEs research has typically included childhood abuse, neglect, and certain household challenges including household mental health problems, household substance use, parental incarceration, and parental divorce or separation [38].”
BackgroundYang, K. G., Essa, A., Noriega-Makarskyy, D. T., Yu, D., Osiecki, L., Gauvin, C. A., Illmann, C., Bortolato, M., Dunn, E. C., Mathews, C. A., et al. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.08.024 · Cited by 12
Patel, S., Johnson, K., Adank, D. N., & Rosas-Vidal, L. E. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100481 · Cited by 10
Kreniske, P., Morrison, C. A., Spencer, B. H., Levine, A., Liotta, L., Fisher, P. W., Nguyen, N., Robbins, R. N., Dolezal, C. L., Kluisza, L., et al. (2022) · Journal of the International AIDS Society · doi:10.1002/jia2.25984 · Cited by 14
“parents divorced and death of family member) typically considered adverse childhood experiences [71], developed by one of the authors (CAM) and providers at a family-based HIV mental health programme for the target population [72, 73], with higher scores indicating more adverse life events.”
BackgroundSocial Determinants of Health and Child Maltreatment Prevention: The Family Success Network Pilot
Johnson‐Motoyama, M., Moon, D. J., Rolock, N., Crampton, D., Nichols, C. B., Haran, H., Zhang, Y., Motoyama, Y., Gonzalez, E., & Sillaman, N. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192215386 · Cited by 12
“Additionally, intergenerational trauma and relational health are addressed through family coaching and assessments of past family traumas using the Adverse Child Experiences (ACE) Study [30], the Brief Child Abuse Potential Inventory (BCAP) [31], and the Protective Factors Survey 2nd Edition (PFS-2) [32].”
MethodClinical Framework for Dismantling Antiblack Racism in the Clinic Room
Herbst, R. B., Corley, A. M. S., & McTate, E. (2023) · Clinical Pediatrics · doi:10.1177/00099228231156009 · Cited by 12
Zhang, Y. B., Mishra, S., Liang, E. N., & Wekerle, C. (2023) · Adversity and Resilience Science · doi:10.1007/s42844-023-00095-z · Cited by 12
A Biocratic Paradigm: Exploring the Complexity of Trauma-Informed Leadership and Creating Presence™
Bloom, S. L. (2023) · Behavioral Sciences · doi:10.3390/bs13050355 · Cited by 15
A U.S. National Study of Family Resilience During the COVID-19 Pandemic
Perry, K. J., Penner, F., Contreras, H. T., Santos, R. P., & Sarver, D. E. (2023) · Journal of Child and Family Studies · doi:10.1007/s10826-023-02581-5 · Cited by 12
“2%) parents endorsing a 1 to 10 on the Adverse Childhood Experiences Questionnaire (Felitti et al., 1998).”
BackgroundCurriculum Violence and Text Selection
Jones, S. P. (2022) · English leadership quarterly · doi:10.58680/elq32105 · Cited by 12
General practice — the integrating discipline
Gray, D. P. (2023) · British Journal of General Practice · doi:10.3399/bjgp23x734697 · Cited by 12
Haapanen, K. A., Christens, B. D., Speer, P. W., & Freeman, H. E. (2023) · American Journal of Community Psychology · doi:10.1002/ajcp.12708 · Cited by 13
Hsieh, S., Chang, Y.-H., Yao, Z., Yang, M., & Yang, C.-T. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1332124 · Cited by 12
Abdelhamid, S., Kraaijenvanger, E. J., Fischer, J., & Steinisch, M. (2024) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-023-02367-6 · Cited by 14
Bouwstenen voor betrokken jeugdbeleid
Reg, W. R. V. H. (2007) · Amsterdam University Press eBooks · doi:10.5117/9789053567586 · Cited by 12
Posttraumatische Belastungsstörung bei Kindern und Jugendlichen
Steil, R., & Rosner, R. (2013) · Springer eBooks · doi:10.1007/978-3-642-35068-9_19 · Cited by 12
Beyond Maltreatment: Developing Support for Children in Multiproblem Families
Wald, M. S. (2013) · Child maltreatment · doi:10.1007/978-94-007-7208-3_13 · Cited by 12
A holistic approach to child maltreatment
Finkelhor, D., & Tucker, C. J. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(15)00173-x · Cited by 12
The Complex Etiology and Lasting Consequences of Child Maltreatment
Etter, D. J., & Rickert, V. I. (2013) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2013.07.010 · Cited by 12
Hahn, R. A., Vesely, S. K., & Chang, M. (2000) · Health Risk & Society · doi:10.1080/713670164 · Cited by 13
Forensic medical evaluations of child maltreatment: A proposed research agenda
Dubowitz, H., Christian, C. W., Hymel, K. P., & Kellogg, N. D. (2014) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2014.07.012 · Cited by 12
Adolescents’ adverse experiences and mental health in a prospective perspective
Haavet, O. R., Sagatun, Å., & Lien, L. (2010) · Scandinavian Journal of Public Health · doi:10.1177/1403494810375491 · Cited by 14
Keesler, J. M. (2014) · Advances in Mental Health and Intellectual Disabilities · doi:10.1108/amhid-04-2013-0028 · Cited by 12
Petrella, C., Giuli, C., Agostini, S., Bacquie, V., Zinni, M., Théodorou, V., Broccardo, M., Casolini, P., & Improta, G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113389 · Cited by 13
The Study of Personality Characteristics and Mental Health in Addicts
Habibi, Z., Sadeghi, H., Haghrangbar, F., et al. (2013) · Procedia - Social and Behavioral Sciences · doi:10.1016/j.sbspro.2013.06.594 · Cited by 12
General Music and Children Living in Poverty
McAnally, E. A. (2013) · Journal of General Music Education · doi:10.1177/1048371313478611 · Cited by 12
Risky sexual behaviors, mental health, and history of childhood abuse among adolescents
Tsutsumi, A., Izutsu, T., & Matsumoto, T. (2012) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2011.12.004 · Cited by 12
Menstrually related mood disorders and a history of abuse: Moderators of pain sensitivity.
Fleischman, D. S., Bunevičius, A., Leserman, J., & Girdler, S. S. (2013) · Health Psychology · doi:10.1037/a0031900 · Cited by 12
Experiências adversas na infância e tentativas de suicídio em adultos com obesidade mórbida
Silva, S., & Maia, Â. (2010) · Revista de Psiquiatria do Rio Grande do Sul · doi:10.1590/s0101-81082010005000002 · Cited by 12
How stress gets under the skin o cómo el estrés psicológico se introduce bajo la piel
Ortíz, M. S., Willey, J. F., & Chiang, J. J. (2014) · Revista médica de Chile · doi:10.4067/s0034-98872014000600011 · Cited by 13
Wood, D. L., Dobbins, I. G., Earls, M. F., Garner, A. S., McGuinn, L. J., Pascoe, J. M., Shonkoff, J. P., & Siegel, B. (2012) · Cited by 13
Selič, P., Švab, I., Rifel, J., Pavlič, D. R., Černe, A., King, M., & Nazareth, I. (2011) · PubMed Central · Cited by 12
Lee, D. D., Bagnato, S. J., & Pretti-Frontczak, K. L. (2016) · Journal of Intellectual Disability - Diagnosis and Treatment · doi:10.6000/2292-2598.2015.03.04.2 · Cited by 12
Life adversity is associated with smoking relapse after a quit attempt
Lemieux, A., Olson, L., Nakajima, M., Schulberg, L., & Al’Absi, M. (2016) · Addictive Behaviors · doi:10.1016/j.addbeh.2016.03.017 · Cited by 12
Child abuse and fabricated or induced illness in the ENT setting: a systematic review
Rees, P., Al‐Hussaini, A., & Maguire, S. (2016) · Clinical Otolaryngology · doi:10.1111/coa.12668 · Cited by 12
Diagnosis and treatment of medically unexplained symptoms and chronic functional syndromes.
Clarke, D. D. (2016) · Families Systems & Health · doi:10.1037/fsh0000228 · Cited by 13
The Role of Gender in Suicidal Ideation among Long-term Opioid Users
Marchand, K., Palis, H., Fikowski, J., Harrison, S., Spittal, P. M., Schechter, M. T., & Oviedo‐Joekes, E. (2017) · The Canadian Journal of Psychiatry · doi:10.1177/0706743717711173 · Cited by 12
Trauma and Very Young Children
Jonson‐Reid, M., & Wideman, E. S. (2017) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2017.02.004 · Cited by 12
Developing Trauma-Informed Care Champions: A Six-Month Learning Collaborative Training Model
Koury, S. P., & Green, S. A. (2017) · Advances in Social Work · doi:10.18060/21303 · Cited by 12
Høifødt, R. S., Nordahl, D., Pfuhl, G., Landsem, I. P., Thimm, J. C., Ilstad, L. K. K., & Wang, C. E. A. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-016005 · Cited by 12
Rosemberg, M.-A. S., Gültekin, L., & Pardee, M. (2017) · Workplace Health & Safety · doi:10.1177/2165079917736070 · Cited by 11
Kiweewa, J. M., Knettel, B. A., & Luke, M. M. (2017) · International Journal for the Advancement of Counselling · doi:10.1007/s10447-017-9316-9 · Cited by 14
Recognizing, Treating, and Preventing Trauma in LGBTQ Youth
Mooney, M. A. (2017) · Journal of Family Strengths · doi:10.58464/2168-670x.1363 · Cited by 11
Larkin, H., Lee, E., Esaki, N., DeMasi, M. E., Trifoso, S., Briar-Lawson, K. H., Dean, E., Weldon, P., Park, J., Bowen, L., et al. (2018) · Social Work in Health Care · doi:10.1080/00981389.2018.1471016 · Cited by 12
EMDR-Based Divorce Recovery Group: A Case Study
Wong, S.-L. (2018) · Journal of EMDR Practice and Research · doi:10.1891/1933-3196.12.2.58 · Cited by 12
Grant, B.-J., Wilkerson, S. B., & Henschel, M. M. (2018) · Journal of Child Sexual Abuse · doi:10.1080/10538712.2018.1483460 · Cited by 12
Child health care coverage and reductions in child physical abuse
McCray, N. (2018) · Heliyon · doi:10.1016/j.heliyon.2018.e00945 · Cited by 12
“The deleterious consequences go beyond physical symptoms: children who suffer abuse are also at higher risk for low academic achievement, abuse of illicit substances, alcoholism, juvenile and adult criminality, and a variety of psychological disorders (Felitti et al., 1998; Lansford et al., 2002; Silverman et al., 199…”
BackgroundAaron, R. V., Noel, M. E., Dudeney, J. E., Wilson, A. C., Holley, A. L., & Palermo, T. M. (2019) · Journal of Behavioral Medicine · doi:10.1007/s10865-019-00016-5 · Cited by 13
All Traumas Are Not Created Equal
Gebauer, S., Moore, R. M., & Salas, J. (2019) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2018.5556 · Cited by 12
Trauma-Informed Care for Infant and Early Childhood Abuse
Fredrickson, R. (2019) · Journal of Aggression Maltreatment & Trauma · doi:10.1080/10926771.2019.1601143 · Cited by 12
“Numerous studies showed that all community systems are affected, including but not limited to child welfare, health care, mental health, criminal justice, employment, education, faith-based organizations, and families (Anda et al., 2005; DeCandia et al., 2014; Felitti et al., 1998; Herman, 1992).”
BackgroundInfluentialEcott, S., Aiolfi, I., & Ciardha, C. Ó. (2019) · Journal of Sexual Aggression · doi:10.1080/13552600.2019.1605625 · Cited by 12
“In this study we examined the effect of adverse childhood experiences on sexual coping and also sexual coercion by using the ACE scale (Felitti et al., 1998), the Coping Using Sex Inventory (Cortoni & Marshall, 2001), and the sexual experiences survey – short form perpetration (Koss et al.”
BackgroundMethodInfluentialRueness, J., Myhre, M. C., Strøm, I. F., Wentzel‐Larsen, T., Dyb, G. A., & Thoresen, S. (2019) · European Journal of Psychotraumatology · doi:10.1080/20008198.2019.1608719 · Cited by 14
“a higher number of child abuse types experienced (Afifi et al., 2016; Clemens et al., 2018; Felitti et al., 1998).”
BackgroundInfluentialEffects of Psychosocial Adversity on School Maladjustment: A Follow-up of Primary School Students
Vargas, B., Leiva, L., Andrade, R. M. R., & Squicciarini, A. M. (2019) · Psicologí a Educativa · doi:10.5093/psed2019a10 · Cited by 12
Early adversity and adult delinquency: the mediational role of mental health in youth offenders
Basto-Pereira, M., & Maia, Â. (2019) · Ciência & Saúde Coletiva · doi:10.1590/1413-81232018248.27142017 · Cited by 12
The Role of the Orthopaedic Surgeon in the Identification and Management of Nonaccidental Trauma
Ranade, S. C., Allen, A. K., & Deutsch, S. A. (2019) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/jaaos-d-18-00348 · Cited by 12
Integrating infant mental health practice models in nursing
Gordon, J. M., Gaffney, K., Slavitt, H. C., Williams, A. A., & Lauerer, J. (2020) · Journal of Child and Adolescent Psychiatric Nursing · doi:10.1111/jcap.12262 · Cited by 12
Segeren, M. W., Fassaert, T., de Wit, M. D., Grimbergen, C., & Popma, A. (2020) · International Journal of Child Abuse & Neglect · doi:10.1016/j.chiabu.2019.104354 · Cited by 12
Adverse Experiences and Special Health Care Needs Among Children
Kan, K., Gupta, R. S., Davis, M. M., Heard‐Garris, N., & Garfield, C. F. (2020) · Maternal and Child Health Journal · doi:10.1007/s10995-020-02874-x · Cited by 12
Shaikh, K., Premji, S., Lalani, S. B., Forcheh, N., Dosani, A., Yim, I. S., Samia, P., Naugler, C. T., & Letourneau, N. L. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.01.180 · Cited by 12
Adler‐Baeder, F. M., & Higginbotham, B. J. (2020) · Family Relations · doi:10.1111/fare.12427 · Cited by 17
Zwi, K. J., Sealy, L., Samir, N., et al. (2020) · BMJ Paediatrics Open · doi:10.1136/bmjpo-2019-000615 · Cited by 12
Banishing “Siberia” and Student Seclusion: Leading Trauma-Informed Systems Change in a Rural School
Biddle, C., & Brown, L. M. (2020) · Journal of Cases in Educational Leadership · doi:10.1177/1555458920910771 · Cited by 13
“…in the home, parental separation (through divorce or removal), or exposure to substance use disorder—have been shown to have long-term detrimental effects on youth development, including poor health outcomes, impacts on learning, and even early death (Edwards et al., 2005; Felitti et al., 1998).”
BackgroundChildhood Adversity and Dimensional Variations in Adult Sustained Attention
Vogel, S. C., Esterman, M. S., Degutis, J. M., Wilmer, J. B., Ressler, K. J., & Germine, L. T. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.00691 · Cited by 12
“This coding scheme is similar to the coding scheme for the Adverse Child Experiences Questionnaire (ACE) (Felitti et al., 1998).”
MethodEhrenthal, J. C., Schauenburg, H., Wagner, F. E., Dinger, U., & Volz, M. (2020) · Psychiatrische Praxis · doi:10.1055/a-1123-1615 · Cited by 12
“208 Ehrenthal JC et al. Entwicklung und Evaluation… Psychiat Prax 2020; 47: 207–213 Originalarbeit denz zu Bagatellisierung und Verleugnung anhand von 3 Items erfasst.”
BackgroundInfluentialSoares, S., López‐Cheda, A., Santos, A. C., Barros, H., & Fraga, S. J. D. S. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104755 · Cited by 12
Virmani, E. A., Hatton‐Bowers, H., Lombardi, C. M., Decker, K. B., King, E. K., Plata-Potter, S. I., & Vallotton, C. D. (2020) · Early Education and Development · doi:10.1080/10409289.2020.1798718 · Cited by 16
A psychoanalytic perspective on victims of domestic violence and coercive control
Brandt, S., & Rudden, M. G. (2020) · International Journal of Applied Psychoanalytic Studies · doi:10.1002/aps.1671 · Cited by 12
Nidey, N., Bowers, K. A., Ammerman, R. T., Shah, A. N., Phelan, K. J., Clark, M. J., Ginkel, J. B. V., & Folger, A. T. (2020) · Annals of Epidemiology · doi:10.1016/j.annepidem.2020.09.015 · Cited by 12
Promoting resiliency in adolescents during a pandemic: A guide for clinicians and parents
Rome, E. S., Dinardo, P. B., & Issac, V. E. (2020) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.87a.20055 · Cited by 12
Walsh, G. M. (2020) · Scottish Affairs · doi:10.3366/scot.2020.0337 · Cited by 12
“The term Adverse Childhood Experiences was first used in a seminal study known as the ‘ACE study’ (Felitti et al, 1998) conducted in the USA.”
MethodHege, A., Bouldin, E. D., Roy, M., Bennett, M., Attaway, P. R., & Reed-Ashcraft, K. B. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17228548 · Cited by 12
“This finding is consistent with the original Felitti [5] study in which researchers reported 64 percent of respondents (n = 17,337) had experienced at least one ACE.”
ResultCorrelates of depression among Black girls exposed to violence
Waller, B., Quinn, C. R., Boyd, D. T., DiClemente, R. J., & Voisin, D. R. (2021) · Journal of Racial and Ethnic Health Disparities · doi:10.1007/s40615-020-00937-x · Cited by 12
“ACEs include any physical, sexual or verbal abuse; neglect and/or household dysfunction, namely family violence, mental illness or incarceration as well as separation or divorce [10].”
BackgroundMoon, D.-S., Bong, S.-J., Kim, B.-N., & Kang, N. R. (2021) · Journal of korean Academy of Child and Adolescent Psychiatry · doi:10.5765/jkacap.200041 · Cited by 12
Sandu, R. D., Anyan, F., & Stergiopoulos, V. (2021) · BMC Public Health · doi:10.1186/s12889-021-10281-2 · Cited by 12
“Childhood trauma was assessed using the Adverse Childhood Experiences (ACE) Scale [33] which asks 10 questions related to childhood abuse and household dysfunction before age 18 years.”
MethodWigham, S., Hatton, C., & Taylor, J. L. (2021) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2021.103914 · Cited by 12
McGraw, J. S., McManimen, S. L., Chinn, J., Angoff, H. D., Docherty, M., & Mahoney, A. (2021) · Journal of Homosexuality · doi:10.1080/00918369.2021.1909396 · Cited by 12
“…abuse (physical and sexual) and household challenges (parent treated violently; substance abuse; parental incarceration, parental mental illness, or parental separation/divorce) (Felitti et al., 1998), which when endorsed and then aggregated together on ACE inventories, comprise one’s “ACE score.””
BackgroundMethodResultInfluentialProtocol for the Mason: Health Starts Here prospective cohort study of young adult college students
Cuellar, A. E., Adams, L. M., de Jonge, L., Espina, V. A., Espinoza, L., Fischer, S. F., Frankenfeld, C. L., Hines, D. A., Kornienko, O., Lawrence, H. Y., et al. (2021) · BMC Public Health · doi:10.1186/s12889-021-10969-5 · Cited by 13
“The prevalence of exposure is computed by summing across the abuse and household dysfunction categories [78].”
MethodHan, Y., Modaresnezhad, M., & Nemati, H. (2021) · Knowledge-Based Systems · doi:10.1016/j.knosys.2021.107164 · Cited by 13
Bucerius, S. M., Oriola, T. B., & Jones, D. J. (2021) · The Police Journal Theory Practice and Principles · doi:10.1177/0032258x211009577 · Cited by 13
“…that those who experience four or more ACEs are at greater risk of heart disease, cancer, alcohol abuse, drugaddiction, and are more likely to become involved in crime and be incarcerated later in life (Danese and McEwen, 2012; Felitti and Anda, 2010; Felitti et al., 1998; Schilling et al., 2008).”
BackgroundFacial emotion recognition in adopted children
Paine, A. L., van Goozen, S. H. M., Burley, D. T., Anthony, R., & Shelton, K. H. (2021) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-021-01829-z · Cited by 13
“We also examined associations between adopted children’s emotion recognition and 2) parent and teacher ratings of their emotional and behavioural problems; 3) their history of early adversity, indexed by a number of cumulative adverse childhood experiences [6, 43]; and 4) adoptive parents’ warm parenting.”
InfluentialAlcohol Policy Scores and Alcohol-Attributable Homicide Rates in 150 Countries
Trangenstein, P. J., Peddireddy, S. R., Cook, W. K., Rossheim, M. E., Monteiro, M. G., & Jernigan, D. H. (2021) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2021.03.020 · Cited by 12
Athlete abuse hurts everyone: vicarious and secondary traumatic stress in sport
Tuakli‐Wosornu, Y. A., Amick, M., Guiora, A. N., et al. (2021) · British Journal of Sports Medicine · doi:10.1136/bjsports-2021-104715 · Cited by 12
Concordance of Children’s Adverse Childhood Experiences Amongst Child, Caregiver, and Caseworker
Lombardi, B. M., Thyberg, C. T., & Bledsoe, S. E. (2021) · Journal of Aggression Maltreatment & Trauma · doi:10.1080/10926771.2021.1960453 · Cited by 12
“…adverse childhood experiences (ACES); child abuse; child maltreatment; child welfare The first Adverse Childhood Experiences (ACEs) study (Felitti et al., 1998) and the subsequent replications (Anda et al., 2006; Briere et al., 2008; Dube et al., 2009; Fuemmeler et al., 2009; Hyman et…”
BackgroundMethodHelton, J. J., Vaughn, M. G., & Schiff, M. (2021) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2021.105447 · Cited by 13
Baiden, P., Onyeaka, H., Kyeremeh, E., Panisch, L. S., LaBrenz, C. A., Kim, Y., & Kunz-Lomelin, A. (2022) · Substance Use & Misuse · doi:10.1080/10826084.2021.2012692 · Cited by 16
“Consistent with prior literature on ACEs and their impact (Dube et al., 2006; Felitti et al., 1998), ACE score was then grouped into the following categories “0 = None”, “1 = One”, “2 = Two”, “3 = Three”, and “4 = Four or more”.”
BackgroundAdolescents Engaged in Radicalisation and Terrorism: A Dimensional and Categorical Assessment
Bronsard, G., Cohen, D., Diallo, I., Pellerin, H., Varnoux, A., Podlipski, M.-A., Gérardin, P., Boyer, L., & Campelo, N. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.774063 · Cited by 12
“Previous research using this scale showed links between childhood maltreatment and public health problems in adults (16).”
Kerman, N., Wang, R., Aubry, T., Distasio, J., Gaetz, S., Hwang, S. W., Latimer, E. A., O’Grady, B., Schwan, K., Somers, J. M., et al. (2022) · Journal of Urban Health · doi:10.1007/s11524-022-00680-0 · Cited by 12
“The ACE-Q was used to assess adverse household-based events prior to 18 years of age.”
MethodSchlafstörungen nach traumatischen Erfahrungen in Kindheit und Jugend: ein Überblick
Bader, K., & Schäfer, V. (2018) · Somnologie - Schlafforschung und Schlafmedizin · Cited by 12
Ontario and the enhanced 18-month well-baby visit: Trying new approaches
Williams, R. C., Clinton, J. M., & Biscaro, A. (2008) · Paediatrics & Child Health · doi:10.1093/pch/13.10.850 · Cited by 12
Resilient Youth in Residential Care
Quisenberry, C. M., & Foltz, R. (2013) · Residential Treatment for Children & Youth · doi:10.1080/0886571x.2013.852448 · Cited by 12
Childhood antecedents of incarceration and criminal justice involvement among homeless veterans.
Tsai, J., & Rosenheck, R. A. (2013) · American Journal of Orthopsychiatry · doi:10.1111/ajop.12050 · Cited by 12
Trauma, anxiety and reported health among HIV-positive persons in Tanzania and the US Deep South
Whetten, K., Whetten, R., Ostermann, J., & Itemba, D. (2008) · AIDS Care · doi:10.1080/09540120801918636 · Cited by 12
Consumer perceptions of trauma assessment and intervention in substance abuse treatment
Sanford, A., Donahue, M. T., & Cosden, M. (2014) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2014.05.011 · Cited by 12
Moore, R. J., & Butow, P. N. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/0-306-48007-7_2 · Cited by 12
Adverse Childhood Experiences and the Mental Health of Veterans
McGuinness, T. M., & Waldrop, J. (2015) · Journal of Psychosocial Nursing and Mental Health Services · doi:10.3928/02793695-20150527-55 · Cited by 12
Fundamentals of Attachment Theory
Hunter, J., Maunder, R., & Le, T. L. (2015) · Springer eBooks · doi:10.1007/978-3-319-23300-0_2 · Cited by 14
Trauma-Informed Care in the NICU: Implications for Early Childhood Development
Marcellus, L., & Cross, S. (2016) · Neonatal Network The Journal of Neonatal Nursing · doi:10.1891/0730-0832.35.6.359 · Cited by 10
Ganser, H. G., Münzer, A., Witt, A., Plener, P. L., Muche, R., Rosner, R., Hagl, M., & Goldbeck, L. (2017) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2017.03.008 · Cited by 14
Metadata
- Authors
- Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., Koss, M. P., & Marks, J. S.
- Affiliations
- Kaiser Permanente (US)
- Centers for Disease Control and Prevention (US)
- Emory University (US)
- University of Arizona (US)
- Corresponding author
- Felitti, Vincent J
- Venue
- American Journal of Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 1998-05
- Volume
- 14
- Issue
- 4
- Pages
- 245-258
- ISSN
- 0749-3797 (ISSN-L)
- OpenAlex
- W2116839388
- Cited by
- 18,943
- References
- 97
- Citations by year
- 2026: 1615 · 2025: 1790 · 2024: 1720 · 2023: 1711 · 2022: 1648 · 2021: 1720 · 2020: 1565 · 2019: 1232 · 2018: 963 · 2017: 825 · 2016: 666 · 2015: 573 · 2014: 446 · 2013: 413 · 2012: 340
- FWCI
- 57.99
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Centers for Disease Control and Prevention (TS-44-10/12)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Health › Intimate Partner and Family Violence
- Social Sciences › Sociology and Political Science › Child Welfare and Adoption
- Keywords
- adverse childhood experiences, childhood abuse, household dysfunction, childhood emotional abuse, child physical abuse, child sexual abuse, alcoholism, drug abuse, depression, suicide attempts, smoking, sexually transmitted infections, obesity, physical inactivity, ischemic heart disease, cancer, chronic lung disease, liver disease, cumulative exposure, leading causes of death
- MeSH terms
- Adult, Aged, Aged, 80 and over, California, Cause of Death, Child, Child Abuse, Family, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Risk Factors, Social Problems, Violence, Health Behavior, Logistic Models, Child of Impaired Parents, Domestic Violence
About these checks
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