Cited by 49Indigenous Health, Education, and RightsSubstance Abuse Treatment and OutcomesGambling Behavior and Treatments

Substance and Behavioral Addictions among American Indian and Alaska Native Populations

Open access
Soto, Claradina, West, Amy E., Ramos, Guadalupe G., Unger, Jennifer B.·2022·International Journal of Environmental Research and Public Health

Abstract

Objective: This paper examines substance and behavioral addictions among American Indian and Alaska Natives (AIAN) to identify the structural and psychosocial risk and cultural protective factors that are associated with substance use and behavioral addictions. Methods: Five databases were used to search for peer reviewed articles through December 2021 that examined substance and behavioral addictions among AIANs. Results: The literature search identified 69 articles. Numerous risk factors (i.e., life stressors, severe trauma, family history of alcohol use) and protective factors (i.e., ethnic identity, family support) influence multiple substance (i.e., commercial tobacco, alcohol, opioid, stimulants) and behavioral (e.g., gambling) addictions. Conclusions: There is a dearth of research on behavioral addictions among AIANs. Unique risk factors in AIAN communities such as historical trauma and socioeconomic challenges have interfered with traditional cultural resilience factors and have increased the risk of behavioral addictions. Future research on resilience factors and effective prevention and treatment interventions could help AIANs avoid behavioral addictions.

AI snapshot

Written from the paper’s full text.

TL;DR

This narrative review synthesizes 69 articles on substance and behavioral addictions among American Indian and Alaska Native (AIAN) populations, identifying historical trauma, poverty, family substance use, and mental/physical health problems as risk factors and cultural identity, family support, and cultural healing as protective factors. It concludes there is a dearth of research on behavioral addictions among AIANs, especially beyond gambling.

Key findings

  • AIANs had the highest drug poisoning death rates in 2013–2017 at 36.9 per 100,000 versus 32.6 per 100,000 for Whites; alcohol-induced deaths were 93.1 per 100,000 for AIANs versus 12.9 for Whites and 12.2 for Latino groups, and the 2019 alcohol-involved death rate among AIANs was 50.5 versus 10.4 per 1,000,000 in the general population.
  • Opioid use was 7.4% among AIAN adults ages 18–25 versus 5.5% in the general population; opioid misuse rose from 4.7% in 2015 to 6.2% in 2018 among AIANs ages 26 and older versus 3.4% in the general population in 2018, with prevalence likely underestimated by approximately 35% due to AIAN race misclassification.
  • Gambling findings included pathological gambling rates of 14% and 10% on two North Dakota Indian reservations versus 6% statewide; 2.2% among American Indians in New Mexico versus 0.9% among non-AIANs; 9.9% among AIAN veterans versus 4.3% among Hispanic veterans; and national problem gambling rates of 18% among AIANs versus 8% in the general population.
  • Risk factors included historical trauma, poverty, acculturation, family substance use, adverse childhood experiences, mental health disorders, and polysubstance use; protective factors included ethnic identity, family support, cultural practices, Wellbriety, and Drum-Assisted Recovery Therapy for Native Americans (DARTNA). Among AIAN adolescents in California, the most prominent lifetime addictions were texting, internet use, love, and shopping, while cigarette use, texting, internet use, and love were most prevalent past-month.

Methods

  • Narrative review using PubMed, Science Direct, Cochrane Library, Ovid, and Google Scholar to identify peer-reviewed articles through December 2021 on substance use disorder and gambling addictions among AIANs; searches were limited to studies conducted in the United States.
  • A two-step inclusion process reviewed titles/abstracts and then full texts; included articles had an AIAN sample or a sample including AIANs, examined SUD and/or behavioral or gambling addictions as outcomes, were in English, and used qualitative, quantitative, or mixed methods; non-peer-reviewed sources were excluded.
  • A total of 69 articles were included and organized using the matrix method and updated integrative review guidelines; most literature consisted of cross-sectional designs, systematic reviews, and qualitative studies.

Limitations

  • The paper states there is a dearth of research on behavioral addictions among AIANs; gambling studies are limited to a few geographic areas and lack specific data on protective factors; many available studies are cross-sectional, so causality is unclear; historical trauma literature is disparate and inconsistent with methodological weaknesses limiting coherent conclusions; and prevalence rates are likely underestimated by approximately 35% due to misclassification of AIAN race.
  • Evident from the text: as a narrative review, no systematic quality appraisal or meta-analysis is reported, and findings rely on heterogeneous study designs and supplementary tables not included in the main text.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.3390/ijerph19052974

Cites

104 of 104 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

79 of 192 cited sources checked · 19 supported · 1 flagged · accuracy not yet measured

  • Premisecitation

    Cultural norms can play a significant role in substance use among AIANs.

    “Cultural norms can play a significant role in substance use among AIANs [30].”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [30] McKinley, 2021, American Indian Alcohol Use from a Sex-Specific Wellness Approach: Exploring Its Associated Physical, Behavioral, and Mental Risk and Protective Factors, J. Evid.-Based Soc. Work source
  • Premisecitation

    A cross-sectional survey found that AIAN adult males drink nearly three times as much alcohol as adult females.

    “A cross-sectional survey found that AIAN adult males drink nearly three times as much alcohol as adult females [30].”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [30] McKinley, 2021, American Indian Alcohol Use from a Sex-Specific Wellness Approach: Exploring Its Associated Physical, Behavioral, and Mental Risk and Protective Factors, J. Evid.-Based Soc. Work source
  • Premisecitation

    The cultural and emotional losses tied to forced relocation have been associated with increased SUD.

    “The cultural and emotional losses tied to forced relocation have been associated with increased SUD [40,42].”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites [40] Castor, 2006, A Nationwide Population-Based Study Identifying Health Disparities between American Indians/Alaska Natives and the General Populations Living in Select Urban Counties, Am. J. Public Health source

      The introductory passage (labeled Abstract in our copy; page unavailable) links urban relocation to federal policies, and the Results report higher alcohol-related mortality among American Indians/Alaska Natives than among the corresponding general populations. The paper does not associate cultural or emotional losses from relocation with increased substance use disorder (SUD), nor does it report SUD rates. (LLM, conf=0.78)

      Experimental — accuracy not yet measured
    • cites [42] Peterson, 2002, Native American Women in Alcohol and Substance Abuse Treatment, J. Health Care Poor Underserved source
  • Premisecitation

    Limited education about substance use and its adverse health effects in AIAN communities is a sociocultural factor in the onset and development of SUD.

    “Another sociocultural factor that plays a role in the onset and development of SUD is limited education about substance use and its adverse health effects in AIAN communities [33].”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [33] Whitesell, 2012, Epidemiology and Etiology of Substance Use among American Indians and Alaska Natives: Risk, Protection, and Implications for Prevention, Am. J. Drug Alcohol Abuse source

      The Etiology section discusses community attitudes, substance-related expectancies, and limited treatment services, but does not identify limited education about substance use or its health effects as a risk factor. A search for education, awareness, and knowledge of harmful effects found no passage making that connection. Page numbers are not available in our copy. (LLM, conf=0.72)

      Experimental — accuracy not yet measured
  • Premisecitation

    AIANs experience acculturation-related challenges due to transition from reservation to urban environments and social demands to fit in with both Native culture and American mainstream practices.

    “AIANs also experience acculturation related challenges, not only because of the transition from reservation to urban environments, but also because of the social demands to fit in with both the Native culture and American mainstream practices [31].”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [31] Kulis, 2006, Social Contexts of Drug Offers among American Indian Youth and Their Relationship to Substance Use: An Exploratory Study, Cult. Divers. Ethn. Minor. Psychol. source

      The passage labeled Abstract reports that minority youth may face pressure to fit within both dominant and minority cultures, supporting the claim's bicultural-pressure component. The Method and Discussion describe youth living on and off reservations in a metropolitan area, but do not say that a transition from reservation to urban life causes acculturation challenges. No page numbers are available in our copy. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
  • May combine two claims. 47
  • Classified as probably not a substantial claim. 14
  • The quote only partly states this claim. 1
  • May combine two claims.

    Premisecitation

    A recent study on AIAN adolescents in California found that the most prominent lifetime addictions were texting, internet use, love, and shopping, while cigarette use, texting, internet use, and love were the most prevalent past-month addictions.

    “A recent study on AIAN adolescents in California found that the most prominent lifetime addictions were texting, internet use, love, and shopping, while cigarette use, texting, internet use, and love (defined as maladaptive relationships that mirror addictive behaviors) were the most prevalent past-month addictions [81,83].”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites [81] Sussman, 2011, Prevalence of the Addictions: A Problem of the Majority or the Minority?, Eval. Health Prof. source

      Split into 2 atoms — 0 confirmed, 0 partially supported, 1 disputed, 0 misattributed, 1 unverifiable. Expand the claim to see per-atom verdicts.

      Checked by a reasoning model — may be wrong.

      Experimental — accuracy not yet measured
    • cites [83] Sussman, S. (2017). Substance and Behavioral Addictions: Concepts, Causes, and Cures, Cambridge University Press.

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    It has been theorized that AIANs are less likely to have the protective variant genes to metabolize alcohol.

    “It has been theorized that AIANs are less likely to have the protective variant genes to metabolize alcohol.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [46] Ehlers, 2013, Evidence for a Genetic Component for Substance Dependence in Native Americans, Am. J. Psychiatry source
  • May combine two claims.

    Premisecitation

    Among AIANs, forced relocation, poverty-related stress, exposure to violence, and substance use are closely associated with each other and with substance use.

    “Among AIANs, forced relocation, poverty-related stress, exposure to violence, and substance use are closely associated with each other and with substance use [30,33,35].”
    Quote in the paperNot a substantial claim2 of 3 sources checked
    • cites [30] McKinley, 2021, American Indian Alcohol Use from a Sex-Specific Wellness Approach: Exploring Its Associated Physical, Behavioral, and Mental Risk and Protective Factors, J. Evid.-Based Soc. Work source

      The Discussion says social and economic marginalization may perpetuate alcohol use among American Indians, and the framework section connects alcohol use with colonization and poverty. The passages do not establish forced relocation or exposure to violence as associated with substance use, nor show that all the listed factors are closely associated with one another. No page numbers were supplied for these passages. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
    • cites [33] Whitesell, 2012, Epidemiology and Etiology of Substance Use among American Indians and Alaska Natives: Risk, Protection, and Implications for Prevention, Am. J. Drug Alcohol Abuse source

      The Individual Risk and Protective Factors section (page not supplied) reports a strong association between trauma exposure or PTSD and substance use among AI/ANs. Contemporary AI/AN Populations mentions federal relocation policies and poverty, but does not link either to substance use; the copy also does not establish the claimed associations among all these factors or specifically identify violence exposure in that association. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
    • cites [35] Walters, 2002, Substance Use among American Indians and Alaska Natives: Incorporating Culture in an “Indigenist” Stress-Coping Paradigm, Public Health Rep.
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Historical trauma has long been conceptually linked to poor health outcomes in AIANs.

    “Historical trauma has long been conceptually linked to poor health outcomes in AIANs [20,21,22,23,24,25].”
    Quote in the paperNot a substantial claim1 of 6 sources checked
    • cites [20] Chase, 2011, Historical Trauma Among Indigenous Peoples of the Americas: Concepts, Researrch, and Clinical Considerations, J. Psychoact. Drugs source
    • cites [21] 2013, Examining the Theory of Historical Trauma Among Native Americans, Prof. Couns.

      Not checked in the free run.

    • cites [22] 2008, Historical Trauma in American Indian/Native Alaska Communities: A Multilevel Framework for Exploring Impacts on Individuals, Families, and Communities, J. Interpers. Violence source
    • cites [23] Mohatt, 2014, Historical Trauma as Public Narrative: A Conceptual Review of How History Impacts Present-Day Health, Soc. Sci. Med. source
    • cites [24] Morgan, 2009, The Healing of Our People: Substance Abuse and Historical Trauma, Subst. Use Misuse source
    • cites [25] Nutton, 2015, Historical Trauma, Substance Use, and Indigenous Peoples: Seven Generations of Harm from a “Big Event”, Subst. Use Misuse source
  • May combine two claims.

    Premisecitation

    Many studies reported significant associations between higher levels of reported historical trauma experience and adverse health outcomes; several studies linked historical trauma to increased substance use.

    “Many studies reported significant associations between higher levels of reported historical trauma experience and adverse health outcomes; specifically, several studies linked historical trauma to increased substance use [26,27,28,29].”
    Quote in the paperNot a substantial claim2 of 4 sources checked
    • cites [26] Ehlers, 2013, Measuring Historical Trauma in an American Indian Community Sample: Contributions of Substance Dependence, Affective Disorder, Conduct Disorder and PTSD, Drug Alcohol Depend. source

      The Discussion reports that participants with lifetime substance dependence had significantly higher historical-loss and associated-symptom scores, supporting an association in this American Indian community sample. It also says the cross-sectional data cannot establish direction: the paper does not show that historical trauma led to increased substance use. The cited passage concerns substance dependence and thoughts about historical loss, rather than a measured increase in substance use. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
    • cites [27] Soto, 2015, Stressful Life Events, Ethnic Identity, Historical Trauma, and Participation in Cultural Activities: Associations with Smoking Behaviors among American Indian Adolescents in California, Addict. Behav. source

      The Results (§3.2, page unavailable) report significant positive paths from historical trauma to both experimental and past-month smoking among American Indian adolescents. The Introduction (§1.2, page unavailable) also describes associations with other adverse outcomes and substance use, but this paper does not establish that many studies found significant associations across those outcomes. (LLM, conf=0.83)

      Experimental — accuracy not yet measured
    • cites [28] Whitbeck, 2004, Conceptualizing and Measuring Historical Trauma among American Indian People, Am. J. Community Psychol. source
    • cites [29] Wiechelt, 2012, Historical Trauma among Urban American Indians: Impact on Substance Abuse and Family Cohesion, J. Loss Trauma source
  • May combine two claims.

    Premisecitation

    Forced relocation contributed to higher levels of poverty among many AIANs and promoted cultural displacement and eroded cultural practices and traditions.

    “In addition to forced relocation contributing to higher levels of poverty among many AIANs, it also promoted cultural displacement and eroded cultural practices and traditions [40,42].”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites [40] Castor, 2006, A Nationwide Population-Based Study Identifying Health Disparities between American Indians/Alaska Natives and the General Populations Living in Select Urban Counties, Am. J. Public Health source

      The Abstract links urban migration to federal relocation policies and mentions social and cultural isolation associated with nonreservation living. The Results report higher poverty rates among AIAN populations. The paper does not establish that forced relocation caused the poverty disparity or eroded cultural practices and traditions; page numbers were not available in our copy. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
    • cites [42] Peterson, 2002, Native American Women in Alcohol and Substance Abuse Treatment, J. Health Care Poor Underserved source
  • May combine two claims.

    Premisecitation

    Family discord and inharmonious parent-child relationships can occur because of parental substance use and also contribute to their children's SUD.

    “Family discord and inharmonious parent-child relationships can also occur because of parental substance use and also contribute to their children’s SUD [64,65,69].”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [64] Burnette, 2016, Risk and Protective Factors Related to the Wellness of American Indian and Alaska Native Youth: A Systematic Review, Int. Public Health J.
    • cites [65] Burnette, 2017, Historical Oppression, Resilience, and Transcendence: Can a Holistic Framework Help Explain Violence Experienced by Indigenous People?, Soc. Work source

      The Family-Level Factors section (page unavailable) describes parental substance abuse, poor communication, impaired parent-child bonds, and family division together. It does not say parental substance use causes the discord or that these family factors contribute to children’s substance use disorder; it discusses risk factors for Indigenous women experiencing intimate partner violence. (LLM, conf=0.83)

      Experimental — accuracy not yet measured
    • cites [69] Dombrowski, 2020, A Systematic Review of Indian Boarding Schools and Attachment in the Context of Substance Use Studies of Native Americans, J. Racial Ethn. Health Disparities source
  • May combine two claims.

    Findingcitation

    Limited experimental and longitudinal research makes it difficult to assert whether polysubstance use is an outcome of substance use addictions or a risk factor for such addictions, although there is some support for the latter.

    “Limited experimental and longitudinal research makes it difficult to assert whether polysubstance use is an outcome of substance use addictions or if polysubstance use is a risk factor for such addictions (or both), although there is some support for the latter [50,56,57].”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [50] Moghaddam, 2014, Nicotine Dependence and Psychiatric and Substance Use Disorder Comorbidities among American Indians/Alaska Natives: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions, Drug Alcohol Depend. source
    • cites [56] Rieckmann, 2012, American Indians with Substance Use Disorders: Treatment Needs and Comorbid Conditions, Am. J. Drug Alcohol Abuse source

      The Methods and Results describe polysubstance use and its association with regular opioid use, but do not address whether polysubstance use precedes or follows addiction. Searches for longitudinal or experimental evidence and for polysubstance use as a risk factor found no passage supporting that causal-direction claim. Page numbers were not available in our copy. (LLM, conf=0.73)

      Experimental — accuracy not yet measured
    • cites [57] Novins, 2006, The Relationship between Patterns of Alcohol Use and Mental and Physical Health Disorders in Two American Indian Populations, Addiction source
  • May combine two claims.

    Premisecitation

    Continually feeling stressed over challenging life events can exacerbate the impact of those stressors on the body and mind, outweigh coping resources and potentially make the use of substances a more appealing option.

    “Continually feeling stressed over challenging life events can exacerbate the impact of those stressors on the body and mind, outweigh coping resources and potentially make the use of substances a more appealing option [31,35,54,55].”
    Quote in the paperNot a substantial claim2 of 4 sources checked
    • cites [31] Kulis, 2006, Social Contexts of Drug Offers among American Indian Youth and Their Relationship to Substance Use: An Exploratory Study, Cult. Divers. Ethn. Minor. Psychol. source

      The Abstract says that acculturation-related pressure on minority youth may make substance use a coping response. It does not address continual stress exacerbating effects on the body and mind or overwhelming coping resources; those parts of the sentence are not supported by this source. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
    • cites [35] Walters, 2002, Substance Use among American Indians and Alaska Natives: Incorporating Culture in an “Indigenist” Stress-Coping Paradigm, Public Health Rep.
    • cites [54] Baldwin, 2011, Culture and Context: Buffering the Relationship between Stressful Life Events and Risky Behaviors in American Indian Youth, Subst. Use Misuse source
    • cites [55] Eitle, 2014, Race, Coping Strategies, and Substance Use Behaviors: A Preliminary Analysis Examining White and American Indian Adolescents, Subst. Use Misuse source
  • May combine two claims.

    Premisecitation

    Suicidal thoughts and attempts are risk factors for SUD as well as potential results of substance use.

    “Often indicative of great levels of despair and hopelessness, is the occurrence of suicidal thoughts and attempts, which are risk factors for SUD as well as potential results of substance use [44,56].”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites [44] Espel, E. (2015). American Indian/Alaska Native Adolescent Suicide: Risk Factors, Protective Factors, and Prevention Opportunities in Education Settings. An Annotated Bibliography, West Comprehensive Center.

      Not checked in the free run.

    • cites [56] Rieckmann, 2012, American Indians with Substance Use Disorders: Treatment Needs and Comorbid Conditions, Am. J. Drug Alcohol Abuse source

      The Introduction describes a bidirectional relationship between substance use and mental health problems generally. The Results (Subsample Analysis; page not provided) find that regular opioid users reported more suicidal thoughts and attempts, but do not establish that suicidality is a risk factor for SUD or a result of substance use. The Methods also specify that the psychiatric history assessed did not directly result from drug or alcohol use. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    AIAN males and females had higher prevalence of both paranoid and antisocial personality disorders as well as drug dependence relative to both sexes in the general population.

    “AIAN males and females had higher prevalence of both paranoid and antisocial personality disorders as well as drug dependence relative to both sexes in the general population [52].”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [52] Beals, 2016, Psychiatric Disorders and Mental Health Treatment in American Indians and Alaska Natives: Results of the National Epidemiologic Survey on Alcohol and Related Conditions, Soc. Psychiatry Psychiatr. Epidemiol. source

      The Results (Lifetime Psychiatric Disorders, Table 2) report higher prevalence of drug dependence and both paranoid and antisocial personality disorders in AIAN men and women. The comparison, however, is with non-Hispanic White men and women, not with the general population as the claim states. (LLM, conf=0.88)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Interpretationcitation

    These three localized studies highlight varied pathological and problem gambling rates among AIAN adults, and all are consistently higher than their counterparts.

    “These three localized studies highlight the varied pathological and problem gambling rates among AIAN adults, and unfortunately are all consistently higher than their counterparts.”
    Quote in the paperSubstantial claim1 of 3 sources checked
    • cites [84] Cozzetto, 1996, Compulsive Gambling in the Indian Community: A North Dakota Case Study, Am. Indian Cult. Res. J. source
    • cites [85] Volberg, R.A., and Bernhard, B. (2006). The 2006 Study of Gambling and Problem Gambling in New Mexico, Responsible Gaming Association of New Mexico. source
    • cites [86] Westermeyer, 2005, Lifetime Prevalence of Pathological Gambling among American Indian and Hispanic American Veterans, Am. J. Public Health source
  • May combine two claims.

    Premisecitation

    Abuse and mental health problems are associated with gambling addictions.

    “Other studies have pointed to the associations among abuse, mental health problems, and gambling addictions [93,94].”
    Quote in the paperNot a substantial claim2 of 2 sources checked
    • cites [93] Dion, 2015, Sexual Abuse, Residential Schooling and Probable Pathological Gambling among Indigenous Peoples, Child Abus. Negl. source
    • cites [94] Kong, 2016, Problem-Gambling Severity and Psychiatric Disorders among American-Indian/Alaska Native Adults, J. Psychiatr. Res. source
  • May combine two claims.

    Premisecitation

    The repercussions of historical trauma continue to be evidenced in current structural racism and social determinants of health that adversely impact AIANs' overall health and outweigh their coping resources.

    “The repercussions of historical trauma continue to be evidenced in current structural racism and social determinants of health that adversely impact AIANs’ overall health and outweigh their coping resources [27,33,43].”
    Quote in the paperNot a substantial claim2 of 3 sources checked
    • cites [27] Soto, 2015, Stressful Life Events, Ethnic Identity, Historical Trauma, and Participation in Cultural Activities: Associations with Smoking Behaviors among American Indian Adolescents in California, Addict. Behav. source

      The Introduction (§1.2 Historical Trauma; page unavailable) describes present-day reminders of historical trauma, including impoverished living conditions, and links trauma to mental-health and substance-use outcomes. The Discussion reports an association with smoking among American Indian adolescents in California. The paper does not establish that current structural racism and social determinants harm AIANs’ overall health or outweigh their coping resources. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
    • cites [33] Whitesell, 2012, Epidemiology and Etiology of Substance Use among American Indians and Alaska Natives: Risk, Protection, and Implications for Prevention, Am. J. Drug Alcohol Abuse source

      The Historical Trauma section says the legacy of colonization and federal assimilation policies continues to affect AI/AN lives. The Contextual Risk and Protective Factors section links social settings and underfunded health services to substance-use disparities. The paper does not specifically say that present-day structural racism and social determinants outweigh AI/ANs’ coping resources or establish that claim for overall health. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
    • cites [43] Gibbs, J.T., and Huang, L.N. (2003). American Indian Children and Adolescents. Children of Color: Psychological Interventions with Culturally Diverse Youth, Jossey-Bass.

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Historical trauma is directly linked to poor health outcomes and increased substance use.

    “Previous research has established historical trauma as directly linked to poor health outcomes and increased substance use [20,21,22,26,27,28,29,99].”
    Quote in the paperNot a substantial claim3 of 8 sources checked
    • cites [20] Chase, 2011, Historical Trauma Among Indigenous Peoples of the Americas: Concepts, Researrch, and Clinical Considerations, J. Psychoact. Drugs source
    • cites [21] 2013, Examining the Theory of Historical Trauma Among Native Americans, Prof. Couns.

      Not checked in the free run.

    • cites [22] 2008, Historical Trauma in American Indian/Native Alaska Communities: A Multilevel Framework for Exploring Impacts on Individuals, Families, and Communities, J. Interpers. Violence source
    • cites [26] Ehlers, 2013, Measuring Historical Trauma in an American Indian Community Sample: Contributions of Substance Dependence, Affective Disorder, Conduct Disorder and PTSD, Drug Alcohol Depend. source

      The Results and Discussion (page numbers unavailable) report an association between historical-loss-related distress and substance dependence in the American Indian community studied. The Discussion explicitly says the cross-sectional data cannot establish the direction of that association. The paper does not establish a direct link from historical trauma to poor health outcomes or increased substance use. (LLM, conf=0.88)

      Experimental — accuracy not yet measured
    • cites [27] Soto, 2015, Stressful Life Events, Ethnic Identity, Historical Trauma, and Participation in Cultural Activities: Associations with Smoking Behaviors among American Indian Adolescents in California, Addict. Behav. source
    • cites [28] Whitbeck, 2004, Conceptualizing and Measuring Historical Trauma among American Indian People, Am. J. Community Psychol. source
    • cites [29] Wiechelt, 2012, Historical Trauma among Urban American Indians: Impact on Substance Abuse and Family Cohesion, J. Loss Trauma source
    • cites [99] Pokhrel, 2014, Historical Trauma and Substance Use among Native Hawaiian College Students, Am. J. Health Behav. source

      The Historical Trauma section reports prior research linking historical trauma with poorer mental health and greater likelihood of substance use among American Indians. But this paper’s Results found that, among Native Hawaiian college students, the path to higher substance use was indirect, through perceived discrimination; the direct path was to lower substance use. It therefore does not support an unqualified direct link to increased substance use. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    Low education, unemployment, few socioeconomic opportunities, untreated historical trauma, higher rates of substance use, and having a casino nearby that serves as the main employer and source of revenue for the community are inequities/risk factors for problematic gambling among AIAN.

    “These inequities and risk factors include low education, unemployment, few socioeconomic opportunities, untreated historical trauma, higher rates of substance use, and having a casino nearby that serves as the main employer and source of revenue for the community [88,89,90,91].”
    Quote in the paperSubstantial claim1 of 4 sources checked
    • cites [88] Dowling, 2017, Early Risk and Protective Factors for Problem Gambling: A Systematic Review and Meta-Analysis of Longitudinal Studies, Clin. Psychol. Rev. source

      Section 1.1 identifies lower socioeconomic status, poor academic performance, substance use, and gambling availability as risk factors among young people; section 4.3 identifies education as a potential protective factor. The paper does not establish these factors specifically for AIAN people, nor does it support the claims about unemployment, untreated historical trauma, or a nearby casino serving as a community’s main employer and revenue source. Page numbers were unavailable in our copy. (LLM, conf=0.88)

      Experimental — accuracy not yet measured
    • cites [89] Potenza, 2019, Gambling Disorder, Nat. Rev. Dis. Prim. source
    • cites [90] Volberg, 1997, Gambling and Problem Gambling among Indigenous Peoples, Subst. Use Misuse source
    • cites [91] Welte, 2017, Predictors of Problem Gambling in the U.S, J. Gambl. Stud. source
  • May combine two claims.

    Premisereasoning

    Family cohesion, parental attachment, and low family conflict are protective.

    “Family cohesion, parental attachment, and low family conflict are also protective [44,77]”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites [44] Espel, E. (2015). American Indian/Alaska Native Adolescent Suicide: Risk Factors, Protective Factors, and Prevention Opportunities in Education Settings. An Annotated Bibliography, West Comprehensive Center.

      Not checked in the free run.

    • cites [77] Allen, 2014, A Protective Factors Model for Alcohol Abuse and Suicide Prevention Among Alaska Native Youth, Am. J. Community Psychol. source

      The Methods (page unavailable) identify cohesion and conflict as components of the family-relationship measure, and the Results and Discussion (pages unavailable) describe Family Characteristics as an indirect protective factor for Alaska Native youth. The paper does not identify parental attachment as a measured factor or establish separate protective effects for cohesion and low conflict. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    Family bonds, healthy parenting role models, consistent socialization, the provision of extended family's love and affection, and cultural teachings were virtually eliminated with AIANs' removal from their lands and social networks.

    “Family bonds, healthy parenting role models, consistent socialization, the provision of extended family’s love and affection, and cultural teachings were virtually eliminated with AIANs’ removal from their lands and social networks [17,54,100,101].”
    Quote in the paperSubstantial claim1 of 4 sources checked
    • cites [17] 2003, The Historical Trauma Response among Natives and Its Relationship with Substance Abuse: A Lakota Illustration, J. Psychoactive Drugs source
    • cites [54] Baldwin, 2011, Culture and Context: Buffering the Relationship between Stressful Life Events and Risky Behaviors in American Indian Youth, Subst. Use Misuse source
    • cites [100] Allen, 2014, Mapping Resilience Pathways of Indigenous Youth in Five Circumpolar Communities, Transcult. Psychiatry source

      The Social Determinants of Resilience section (page unavailable) describes forced assimilation, including removal of children to boarding schools, and policies that weakened Indigenous peoples’ connection to land and suppressed culture. It does not say that removal virtually eliminated family bonds, parenting role models, extended-family affection, or cultural teachings across AIAN populations. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
    • cites [101] Burnette, 2016, Historical Oppression and Indigenous Families: Uncovering Potential Risk Factors for Indigenous Families Touched by Violence, Fam. Relat. source
  • May combine two claims.

    Premisecitation

    Developing a strong ethnic identity, and holding and passing on knowledge of the culture, traditions, and languages through generations has been particularly protective among AIANs.

    “Developing a strong ethnic identity, and holding and passing on knowledge of the culture, traditions, and languages through generations has been particularly protective among this population.”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [24] Morgan, 2009, The Healing of Our People: Substance Abuse and Historical Trauma, Subst. Use Misuse source
    • cites [102] Dickerson, 2012, Utilizing Drumming for American Indians/Alaska Natives with Substance Use Disorders: A Focus Group Study, Am. J. Drug Alcohol Abuse source

      The Results (‘Benefits of Drumming’; page unavailable) report participants’ view that developing cultural identity and connecting with culture could help AI/AN people with substance use disorders. The paper does not address language preservation or passing cultural knowledge between generations, and it does not establish a protective effect across AI/AN populations generally. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
    • cites [103] 2002, Using Reasons for Living to Connect to American Indian Healing Traditions: Symposium on Native American Wellness, J. Sociol. Soc. Welf.

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Reconnecting with the Native culture, building internal strengths, coping resources, and relying on extended social networks and multi-generational relationships assist AIANs with navigating the historical and every day hardships experienced.

    “Reconnecting with the Native culture, building internal strengths, coping resources, and relying on extended social networks and multi-generational relationships assist AIANs with navigating the historical and every day hardships experienced [102,104,105].”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [102] Dickerson, 2012, Utilizing Drumming for American Indians/Alaska Natives with Substance Use Disorders: A Focus Group Study, Am. J. Drug Alcohol Abuse source

      The Discussion (page not provided) says a culturally based drumming program could help participants grow in cultural identity, and the Results describe a possible self-esteem benefit for urban AI/AN participants recovering from substance use. The paper does not establish that extended social networks or multigenerational relationships help AI/ANs navigate historical and everyday hardships, and its proposed benefits are narrower than the citing sentence suggests. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
    • cites [104] Abbott, 1998, Traditional and Western Healing Practices for Alcoholism in American Indians and Alaska Natives, Subst. Use Misuse source
    • cites [105] Hodge, 2009, Moving from Colonization toward Balance and Harmony: A Native American Perspective on Wellness, Soc. Work source
  • May combine two claims.

    Premisecitation

    Engaging in culturally healing practices (e.g., sweats) and utilizing medicines (e.g., sage, sweet grass) support recovery and promote well-being.

    “Engaging in culturally healing practices (e.g., sweats) and utilizing medicines (e.g., sage, sweet grass) support recovery and promote well-being [24,102,103].”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [24] Morgan, 2009, The Healing of Our People: Substance Abuse and Historical Trauma, Subst. Use Misuse source
    • cites [102] Dickerson, 2012, Utilizing Drumming for American Indians/Alaska Natives with Substance Use Disorders: A Focus Group Study, Am. J. Drug Alcohol Abuse source

      The Introduction (page unavailable) identifies sage preparation among Indigenous healing methods proposed as promising for reducing substance abuse, and the Results describe participants’ views of drumming as healing. The paper does not address sweats or sweet grass, and its focus-group findings do not establish that these practices support recovery and well-being. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
    • cites [103] 2002, Using Reasons for Living to Connect to American Indian Healing Traditions: Symposium on Native American Wellness, J. Sociol. Soc. Welf.

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    DARTNA has been shown to benefit AIANs in recovery, enhance cognition, and decrease physical ailments.

    “This drumming intervention has been shown to benefit AIANs in recovery, enhance cognition, and decrease physical ailments [106,107,108].”
    Quote in the paperNot a substantial claim2 of 3 sources checked
    • cites [106] Dickerson, 2021, Drum-Assisted Recovery Therapy for Native Americans (DARTNA): Results from a Feasibility Randomized Controlled Trial, J. Subst. Abuse Treat. source
    • cites [107] Dickerson, 2012, Substance Use Patterns among High-Risk American Indians/Alaska Natives in Los Angeles County, Am. J. Addict. source

      The Discussion (page unavailable) reports substance-use patterns among urban AI/ANs and recommends further prevention and treatment research. Searches for DARTNA, drumming, cognition, and physical ailments found no passage addressing the intervention or its claimed benefits. (LLM, conf=0.76)

      Experimental — accuracy not yet measured
    • cites [108] Dickerson, 2014, Drum-Assisted Recovery Therapy for Native Americans (DARTNA): Results from a Pretest and Focus Groups, Am. Indian Alaska Nativ. Ment. Health Res. source

      The Results (DARTNA Pretest: Additional Measures; page not available) report improved medical status and physical/functioning scores among pretest completers, supporting possible recovery-related and physical benefits. But the same section says there was no noticeable improvement on the cognitive-function measure. The Discussion also cautions that the pretest was small and had no comparison group, so it does not establish a general benefit for AI/ANs in recovery. (LLM, conf=0.90)

      Experimental — accuracy not yet measured
  • Probably not a substantial claim: may not pass S4 (based).

    Findingnone given

    Risk and protective factors within AIAN communities are not well understood.

    “Although several articles have reported on the prevalence of substance use and other behavioral addictions in AIAN communities, the risk and protective factors within AIAN communities are not well understood.”
    Quote in the paperNot a substantial claim
  • The quote only partly states this claim.

    Findingown data

    The literature search identified 69 peer-reviewed articles examining substance and behavioral addictions among AIANs through December 2021.

    “The literature search identified 69 articles.”
    • Also stated in: § 2.1. Literature Review · plain
      “A total of 69 articles were utilized in the review and are described in Supplementary Tables S1–S3.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    Gambling appears to be the most thoroughly studied addiction among AIANs, but this literature lacks specific data on protective factors associated with gambling addiction.

    “Gambling appears to be the most thoroughly studied addiction among AIANs (Please see Supplementary Table S3); however, this literature lacks specific data on the protective factors associated with this addiction.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim.

    Findingnone given

    Many of the available studies are cross-sectional where the direction of causality is not clear.

    “There is also great need for longitudinal studies to confidently establish risk and protective factors, as many of the available studies are cross-sectional where the direction of causality is not clear.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Premisecitation

    Urban environments away from reservations increased alienation and exposure to discrimination among AIANs.

    “Urban environments away from reservations limited AIANs’ accessibility to social and family networks [39,43], increased alienation [44], exposure to discrimination, and potentially increased the risk of engaging in substance use [39].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [44] Espel, E. (2015). American Indian/Alaska Native Adolescent Suicide: Risk Factors, Protective Factors, and Prevention Opportunities in Education Settings. An Annotated Bibliography, West Comprehensive Center.

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Poverty-related financial stress intensifies family tensions, and some AIAN report that this is a major contributor to violence in the household.

    “Poverty-related financial stress intensifies family tensions, and some AIAN report that this is a major contributor to violence in the household [38,39].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [38] Jones, 2008, The Distinctive Characteristics and Needs of Domestic Violence Victims in a Native American Community, J. Fam. Violence source
    • cites [39] Lafromboise, 2006, Family, Community, and School Influences on Resilience among Family, Community, and School Influences on Resilience among American Indian Adolescents in the Upper Midwest American Indian Adolescents in the Upper Midwest, J. Community Psychol. source
  • May combine two claims.

    Interpretationreasoning

    Unique risk factors in AIAN communities such as historical trauma and socioeconomic challenges have interfered with traditional cultural resilience factors and have increased the risk of behavioral addictions.

    “Unique risk factors in AIAN communities such as historical trauma and socioeconomic challenges have interfered with traditional cultural resilience factors and have increased the risk of behavioral addictions.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    A recent systematic review concluded that the literature linking historical trauma to health outcomes, including substance use, is still too disparate and inconsistent to make coherent conclusions about the nature of the association.

    “A recent systematic review (SR) examined the extent of empirical evidence that linked the experience of historical trauma to health outcomes and concluded that, while the literature is growing, it is still too disparate and inconsistent to make any coherent conclusions about the nature of the association between historical trauma and health outcomes, including substance use [19].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [19] Gone, 2019, The Impact of Historical Trauma on Health Outcomes for Indigenous Populations in the USA and Canada: A Systematic Review, Am. Psychol. source
  • May combine two claims.

    Interpretationcitation

    Multiple poverty and violence related stressors contribute to and are closely tied to substance use.

    “While causal relationships cannot be drawn, it can be inferred that multiple poverty and violence related stressors contribute to and are closely tied to substance use [38].”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites [38] Jones, 2008, The Distinctive Characteristics and Needs of Domestic Violence Victims in a Native American Community, J. Fam. Violence source
  • May combine two claims.

    Premisecitation

    AIANs started to consume alcohol after being introduced to it by colonists, but they had limited time to develop enzyme systems that facilitated alcohol metabolism.

    “AIANs started to consume alcohol after being introduced to it by colonists, but they had limited time to develop enzyme systems that facilitated alcohol metabolism [45].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [45] Beauvais, 1998, American Indians and Alcohol, Alcohol Heal. Res. World
  • May combine two claims.

    Premisecitation

    Family bonds and parental attachments were severed when AIANs were sent to boarding schools and these occurrences hindered AIANs' ability to trust, communicate and build relationships with loved ones.

    “Family bonds and parental attachments were severed when AIANs were sent to boarding schools and these occurrences hindered AIANs’ ability to trust, communicate and build relationships with loved ones [69].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [69] Dombrowski, 2020, A Systematic Review of Indian Boarding Schools and Attachment in the Context of Substance Use Studies of Native Americans, J. Racial Ethn. Health Disparities source
  • May combine two claims.

    Interpretationreasoning

    Higher prevalence of mental health disorders is associated with more substance use, contributing to a high public health burden of dual diagnoses in AIANs.

    “Higher prevalence of mental health disorders is associated with more substance use, which contributes to an especially high public health burden of these dual diagnoses in AIANs.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Premisecitation

    Paternal substance use can lead to feelings of abandonment among children, potentially also contributing to substance use to alleviate the painful feelings.

    “Moreover, paternal substance use can lead to feelings of abandonment among children, potentially also contributing to substance use to alleviate the painful feelings [67].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [67] Hurdle, 2003, Family Influences on Alcohol and Drug Use by American Indian Youth: Implications for Prevention, J. Fam. Soc. Work source
  • May combine two claims.

    Interpretationcitation

    Biology is a potential risk factor for alcohol abuse in AIANs, as AIANs are less likely to have variations of genes that are essential to effectively metabolize alcohol.

    “It appears that biology is a potential risk factor for alcohol abuse in this population, as AIANs are less likely to have variations of genes that are essential to effectively metabolize alcohol [47].”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites [47] Mulligan, 2003, Allelic Variation at Alcohol Metabolism Genes (ADH1B, ADH1C, ALDH2) and Alcohol Dependence in an American Indian Population, Hum. Genet. source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Some researchers explain that people experiencing depression self-medicate through substance use to cope and obtain relief from emotional pain.

    “Some researchers explain that people experiencing depression self-medicate through substance use to cope and obtain relief from emotional pain [54].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [54] Baldwin, 2011, Culture and Context: Buffering the Relationship between Stressful Life Events and Risky Behaviors in American Indian Youth, Subst. Use Misuse source
  • May combine two claims.

    Premisecitation

    Experiencing acute physical ailments is positively associated with frequently consuming large quantities of alcohol, an association that might be bidirectional.

    “Experiencing acute physical ailments is also positively associated with frequently consuming large quantities of alcohol, an association that might be bidirectional [57].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [57] Novins, 2006, The Relationship between Patterns of Alcohol Use and Mental and Physical Health Disorders in Two American Indian Populations, Addiction source
  • May combine two claims.

    Interpretationreasoning

    These experiences left many AIANs with pressures of finding new ways of living in new remote areas with limited opportunities and with multiple reasons for wanting to escape, depleting their emotional well-being and coping abilities.

    “These experiences left many AIANs with the pressures of finding new ways of living in new remote areas that had limited opportunities for growth and with multiple reasons for wanting to potentially escape what they were experiencing and depleting their emotional well-being and coping abilities.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    Wellbriety is a peer-led, effective intervention for SUD and other emotional disorders that incorporates various protective factors including connecting to and enhancing individuals' spirituality, building on ancestors' resilience, and involving emotional, mental, physical, and spiritual dimensions in all aspects of health.

    “For instance, Wellbriety is a peer-led, effective intervention for SUD and other emotional disorders that incorporates various protective factors including connecting to and enhancing individuals’ spirituality, building on ancestors’ resilience, and involving emotional, mental, physical, and spiritual dimensions in all aspects of health [73].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [73] Moore, 2010, The Multicultural Wellbriety Peer Recovery Support Program: Two Decades of Community-Based Recovery, Alcohol. Treat. Q. source
  • May combine two claims.

    Premisecitation

    Healing practices build spiritual identity and promote health behaviors.

    “Healing practices build spiritual identity and promote health behaviors [72].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [72] Lewton, 2000, Identity and Healing in Three Navajo Religious Traditions: Sa’ah Naaghai Bik’eh Hozho, Med. Anthropol. Q. source
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationnone given

    Family-related risk factors can be traced back to severed family relationships that occurred with forced separation and boarding school experiences.

    “Family related risk factors can also be traced back to severed family relationships that occurred with forced separation and boarding school experiences.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationnone given

    Mental and physical health challenges among AIANs are largely related to restricted availability of culturally sensitive care and accessibility of healthcare services.

    “Mental and physical health challenges are largely related to restricted availability of culturally sensitive care and accessibility of healthcare services.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationreasoning

    A casino could be lucrative to a Tribe overall but harmful to some individual members if they are at increased risk for problematic gambling, especially among a population that has few other economic opportunities.

    “A casino could be lucrative to a Tribe overall but harmful to some individual members if they are at increased risk for problematic gambling, especially among a population that has few other economic opportunities.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    Cultural identification and embracing cultural characteristics, norms, and traditional values can increase community cohesiveness, foster wellness, and reduce distress among AIAN.

    “In turn, cultural identification and embracing cultural characteristics, norms, and traditional values can increase community cohesiveness, foster wellness, and reduce distress among AIAN [35,54].”
    Quote in the paperSubstantial claim0 of 2 sources checked
    • cites [35] Walters, 2002, Substance Use among American Indians and Alaska Natives: Incorporating Culture in an “Indigenist” Stress-Coping Paradigm, Public Health Rep.
    • cites [54] Baldwin, 2011, Culture and Context: Buffering the Relationship between Stressful Life Events and Risky Behaviors in American Indian Youth, Subst. Use Misuse source
  • May combine two claims.

    Interpretationreasoning

    Multiple risk factors contribute to the higher prevalence of these addictions, with many of these factors arguably tracing back to the historical trauma experienced by AIANs.

    “Multiple risk factors contribute to the higher prevalence of these addictions, with many of these factors arguably tracing back to the historical trauma experienced by AIANs.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: Substance use and gambling addictions have a higher prevalence among AIAN.
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationreasoning

    AIANs could be more likely to live near casinos, work at casinos, or view casinos as a beneficial part of their community because many AIAN Tribes operate casinos on their sovereign land to earn income for the Tribe.

    “Because many AIAN Tribes operate casinos on their sovereign land to earn income for the Tribe, AIANs could be more likely to live near casinos, work at casinos, or view casinos as a beneficial part of their community.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationreasoning

    Substance use and gambling addictions are significant concerns among the AIAN population.

    “Substance use and gambling addictions are significant concerns among the AIAN population.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Premisecitation

    With forced removals, AIANs lost their social support and valuable resources, and had to start anew with very limited assets and means of sustenance.

    “With forced removals, AIANs lost their social support and valuable resources, and had to start anew with very limited assets and means of sustenance [22,35].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [22] 2008, Historical Trauma in American Indian/Native Alaska Communities: A Multilevel Framework for Exploring Impacts on Individuals, Families, and Communities, J. Interpers. Violence source
    • cites [35] Walters, 2002, Substance Use among American Indians and Alaska Natives: Incorporating Culture in an “Indigenist” Stress-Coping Paradigm, Public Health Rep.
  • May combine two claims.

    Premisecitation

    Forced relocation and boarding school separations left many generations of AIANs without their parents, and consequently, without good parenting role models or the support of multigenerational families.

    “Forced relocation and boarding school separations left many generations of AIANs without their parents, and consequently, without good parenting role models or the support of multigenerational families [69].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [69] Dombrowski, 2020, A Systematic Review of Indian Boarding Schools and Attachment in the Context of Substance Use Studies of Native Americans, J. Racial Ethn. Health Disparities source
  • May combine two claims.

    Premisecitation

    Attachment injuries were passed on generationally, complicating the process of successfully navigating interpersonal relationship challenges and potentially led to substance use.

    “Attachment injuries were passed on generationally, complicating the process of successfully navigating interpersonal relationship challenges and potentially led to substance use [69].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [69] Dombrowski, 2020, A Systematic Review of Indian Boarding Schools and Attachment in the Context of Substance Use Studies of Native Americans, J. Racial Ethn. Health Disparities source
  • May combine two claims.

    Premisecitation

    Cultural practices such as storytelling to enhance resilience are protective, as they often remind AIANs of their ancestors, their resilience, and the value of their practices.

    “Additionally, cultural practices such as storytelling to enhance resilience are also protective, as they often remind AIANs of their ancestors, their resilience, and the value of their practices [74,75].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [74] Whitbeck, 2012, Substance Abuse Prevention in American Indian and Alaska Native Communities, Am. J. Drug Alcohol Abuse source
    • cites [75] Substance Abuse and Mental Health Services Administration [SAMHSA], Indian Health Service, Park-Lee, E., Lipari, R.N., Bose, J., Hughes, A., Greenway, K., RTI International, Glasheen, C., and Herman-Stahl, M. (2022, February 07). Substance Use and Mental Health Issues among U.S.-Born American Indians or Alaska Natives Residing on and off Tribal Lands, Available online: https://www.samhsa.gov/data/sites/default/files/cbhsq-reports/DRAIANTribalAreas2018/DRAIANTribalAreas2018.htm.

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Emotion regulation, valuing ethnic identity, empowerment, and activism also promote mental health in AIAN populations.

    “Emotion regulation, valuing ethnic identity, empowerment, and activism also promote mental health in this population [76].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [76] Kirmayer, 2011, Rethinking Resilience from Indigenous Perspectives, Can. J. Psychiatry source
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationnone given

    Other behavioral addictions probably exist in the AIAN community, as in any community, but almost no research exists.

    “Other behavioral addictions probably exist in this community, as in any community, but almost no research exists.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim.

    Interpretationreasoning

    Programs developed by the AIAN people for the AIAN community allow for methodologies that fit AIAN ideologies rather than being confined to Westernized frameworks.

    “Programs developed by the AIAN people for the AIAN community allow for methodologies that fit AIAN ideologies rather than being confined to Westernized frameworks.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Premisecitation

    Attendees of such programs have shown higher levels of spiritual connectedness and significant reductions in depression and anxiety.

    “Attendees of such programs have shown higher levels of spiritual connectedness and significant reductions in depression and anxiety [106].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [106] Dickerson, 2021, Drum-Assisted Recovery Therapy for Native Americans (DARTNA): Results from a Feasibility Randomized Controlled Trial, J. Subst. Abuse Treat. source
  • May combine two claims.

    Premisecitation

    Culturally tailored telepsychiatry in a residential treatment setting was effective in promoting treatment engagement and improving completion rates among Alaska Natives.

    “Another program that utilized culturally tailored telepsychiatry in a residential treatment setting was also effective in promoting treatment engagement and improving completion rates among Alaska Natives [109].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [109] Legha, 2020, Telepsychiatry in an Alaska Native Residential Substance Abuse Treatment Program, Telemed. e-Health source
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).

    Interpretationnone given

    Understanding the gambling addiction and why AIANs engage in gambling can support future interventions to reduce gambling urges.

    “Understanding the gambling addiction and why AIANs engage in gambling can support future interventions to reduce gambling urges.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationreasoning

    These indigenous approaches are based on indigenous centered priorities that include AIANs to develop frameworks based on community values and perspective.

    “These indigenous approaches are based on indigenous centered priorities that include AIANs to develop frameworks based on community values and perspective.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).

    Interpretationnone given

    There are probably other risk and protective factors that have yet to be identified to understand SUD problems in AIAN populations.

    “Lastly, there are probably other risk and protective factors that have yet to be identified to understand SUD problems in AIAN populations and deserve more attention.”
    Quote in the paperNot a substantial claim
60 of 60
  • The paper relies on this without support.

    AIAN have an increased risk for gambling addiction.

    “The increased risk for gambling addiction among AIAN might be due to other inequities faced by AIAN that are also risk factors for problematic gambling.”
  • The paper relies on this without support.

    Substance use and gambling addictions have a higher prevalence among AIAN.

    “Multiple risk factors contribute to the higher prevalence of these addictions, with many of these factors arguably tracing back to the historical trauma experienced by AIANs.”
2 of 2

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

  • Historical-trauma conclusion conflicts with review's stated uncertainty

    Major

    The results say the evidence is too inconsistent to support coherent conclusions about the association with health outcomes, including substance use. The discussion instead says previous research has established a direct link.

  • Review discusses behavioral addictions beyond gambling

    Minor

    The discussion says the literature on this population only includes substance use and gambling addiction, but the results describe a study of texting, internet-use, love, and shopping addictions among AIAN adolescents.

  • Alcohol death rates use incompatible units

    Minor

    The 2019 AIAN rate is given per 1,000,000, while the 2006 rate is given per 100,000. On those stated units, the 2019 rate is 5.05 per 100,000-lower than 30.8 per 100,000, not 64% higher.

3 of 3

Cites

Flagged first, then by citations

Research works printed but not linked: 3

  1. Sussman, S. (2017). Substance and Behavioral Addictions: Concepts, Causes, and Cures, Cambridge University Press.
  2. 2020, Risk Factors Associated with Substance Use in Female Victims of Abuse Living in a Context of Poverty, An. Psicol., 36, 173
  3. 2002, Using Reasons for Living to Connect to American Indian Healing Traditions: Symposium on Native American Wellness, J. Sociol. Soc. Welf., 29, 55

Cited by

Sorted by citations

Authors
Soto, C., West, A. E., Ramos, G. G., & Unger, J. B.
Affiliations
University of Southern California (US)
Corresponding author
Soto, Claradina
Venue
International Journal of Environmental Research and Public Health
Publisher
MDPI AG
Published
2022-03-03
Volume
19
Issue
5
Pages
2974
ISSN
1660-4601 (ISSN-L)
OpenAlex
W4214822883
Cited by
49
References
103
Citations by year
2026: 10 · 2025: 19 · 2024: 9 · 2023: 10 · 2022: 1
FWCI
7.46
Type
journal article
Language
en
Open access
Locations
  • International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (acceptedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Social Sciences › Health › Indigenous Health, Education, and Rights
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
Keywords
American Indian and Alaska Native populations, substance use, behavioral addiction, gambling addiction, tobacco use, alcohol consumption, opioid use, stimulant use, historical trauma, life events, family history of alcohol use, ethnic identity, family support, cultural resilience, protective factors, risk factors, socio-economic problems
MeSH terms
Alaska Natives, Alaskan Natives, Humans, Indians, North American, Behavior, Addictive, Substance-Related Disorders, American Indian or Alaska Native

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-27.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-27.

Cited sources are checked by gpt-6-sol.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

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