The DOI matches its Crossref record; 94 of the 96 references it cites were found in a registry or an index.
Improvements in heart rate variability with exercise therapy
Open accessAbstract
Heart rate variability (HRV) is a noninvasive, practical and reproducible measure of autonomic nervous system function. A heart rate that is variable and responsive to demands is believed to bestow a survival advantage, whereas reduced HRV may be associated with poorer cardiovascular health and outcomes. In recent years, many researchers have investigated the prognostic implications of HRV in a variety of clinical populations. Evidence suggests that reduced HRV has prognostic significance for individuals with myocardial infarction, chronic heart failure, unstable angina and diabetes mellitus. Interventions to increase HRV, such as exercise therapy, have also been examined. The findings of the present review suggest that exercise therapy may improve HRV in myocardial infarction, chronic heart failure and revascularization patients by increasing vagal tone and decreasing sympathetic activity. One hypothesis is that a shift toward greater vagal modulation may positively affect the prognosis of these individuals. While the underlying mechanisms by which exercise training improves vagal modulation are speculative at present, angiotensin II and nitric oxide may be potential mediators.
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“Both yoga and physical activity increase HRV [65,66]”
From A randomized controlled trial of yoga vs nonaerobic exercise for veterans with PTSD: Understanding efficacy, mechanisms of change, and mode of delivery (2021) · cites this paper as [66]
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Cites
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The effects of physical activity on sleep: A meta-analytic review
Kredlow, M. A., Capozzoli, M. C., Hearon, B. A., Calkins, A. W., & Otto, M. W. (2015) · Journal of Behavioral Medicine · doi:10.1007/s10865-015-9617-6 · Cited by 1,333
Mikkelsen, K., Stojanovska, L., Polenakovic, M., Bosevski, M., & Apostolopoulos, V. (2017) · Maturitas · doi:10.1016/j.maturitas.2017.09.003 · Cited by 1,072
Exercise is the real polypill.
Fiuza-Luces, C., Garatachea, N., Berger, N. A., & Lucia, A. (2013) · Physiology · doi:10.1152/physiol.00019.2013 · Cited by 791
Exercise Attenuates the Major Hallmarks of Aging
Garatachea, N., Pareja-Galeano, H., Sanchis-Gomar, F., Santos-Lozano, A., Fiuza-Luces, C., Morán, M., Emanuele, E., Joyner, M. J., & Lucia, A. (2015) · Rejuvenation Research · doi:10.1089/rej.2014.1623 · Cited by 413
Exercise, inflammation and aging.
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Metadata
- Authors
- Routledge, F. S., Campbell, T. S., McFetridge-Durdle, J. A., & Bacon, S. L.
- Affiliations
- Dalhousie University (CA)
- University of Calgary (CA)
- Concordia University (CA)
- Corresponding author
- Routledge, Faye S.
- Venue
- Canadian Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 26
- Issue
- 6
- Pages
- 303-312
- ISSN
- 0828-282X (ISSN-L)
- PMC
- PMC2903986
- OpenAlex
- W2057649886
- Cited by
- 381
- References
- 96
- Citations by year
- 2026: 9 · 2025: 26 · 2024: 24 · 2023: 23 · 2022: 24 · 2021: 41 · 2020: 23 · 2019: 43 · 2018: 22 · 2017: 28 · 2016: 24 · 2015: 25 · 2014: 19 · 2013: 18 · 2012: 20
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Canadian Journal of Cardiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- heart rate variability, exercise therapy, autonomic nervous system, vagal tone, sympathetic activity, myocardial infarction, chronic heart failure, revascularization, prognosis, angiotensin II, nitric oxide
- MeSH terms
- Cardiac Rehabilitation, Autonomic Nervous System, Cardiovascular Diseases, Exercise Therapy, Heart Rate, Humans, Prognosis
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