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FETAL BIOPHYSICAL PROFILE
Abstract
This article begins with an outline of the theoretic basis of the fetal biophysical profile, the method for the biophysical profile score (BPS), and the timing and frequency of testing. The article further discusses the clinical management based on test scores; modified methods of the BPS; and clinical application, predictive accuracy, and impact on outcome of BPS. The authors specifically examine the relationship between BPS and cerebral palsy. They conclude with a discussion of adult sequelae and fetal adaptation to asphyxia.
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“The biophysical profile is not considered part of the routine mid-trimester scan 45 .”
From ISUOG Practice Guidelines (updated): performance of the routine mid‐trimester fetal ultrasound scan (2022) · cites this paper as [45]
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Das, S. K., Jaganmohan Rao, L., Subudhi, M., & Krishnamma, B. S. (2016) · Journal of Evolution of Medical and Dental Sciences · doi:10.14260/jemds/2016/1674
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Metadata
- Authors
- Manning, F. A.
- Affiliations
- Albert Einstein College of Medicine (US)
- Corresponding author
- Manning, Frank A.
- Venue
- Obstetrics and Gynecology Clinics of North America
- Publisher
- Elsevier BV
- Published
- 1999-12
- Volume
- 26
- Issue
- 4
- Pages
- 557-577
- ISSN
- 0889-8545 (ISSN-L)
- OpenAlex
- W2089632175
- Cited by
- 117
- References
- 37
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 2 · 2022: 11 · 2021: 5 · 2020: 4 · 2019: 1 · 2018: 6 · 2017: 3 · 2016: 8 · 2015: 4 · 2014: 3 · 2013: 4 · 2012: 10
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Obstetrics and Gynecology Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Neonatal and fetal brain pathology
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
- Keywords
- fetal biophysical profile, fetal heart rate monitoring, nonstress test, fetal breathing movements, fetal hypoxemia, fetal acidosis, perinatal mortality, perinatal morbidity, antepartum fetal surveillance, fetal oxygenation, fetal lung maturity
- MeSH terms
- Adult, Female, Fetal Hypoxia, Embryonic and Fetal Development, Humans, Pregnancy, Pregnancy Outcome, Reference Values, Sensitivity and Specificity, Cardiotocography, Ultrasonography, Prenatal, Practice Guidelines as Topic
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