Cited by 30Inflammatory Bowel DiseaseClinical Nutrition and GastroenterologyOcular Diseases and Behçet’s Syndrome

Nutritional factors in inflammatory bowel disease

Graham, Toby O, Kandil, Hossam M·2002·Gastroenterology Clinics of North America

Abstract

Dietary antigens may act as important stimuli of the mucosal immune system and have led to the study of nutritional therapy for IBD. Patients with active CD respond to bowel rest, along with total enteral nutrition or TPN. Bowel rest and TPN are as effective as corticosteroids at inducing remission for patients with active CD, although benefits are short-lived. Enteral nutrition is consistently less effective than conventional corticosteroids for treatment of active CD. Use of palatable, liquid polymeric diets in active CD is controversial, but these diets are of equal efficacy when compared with elemental diets. UC has not been treated effectively with either elemental diets or TPN. Fish oil contains n-3-PUFA, which inhibits production of proinflammatory cytokines and has some benefit in the treatment of CD. Topical applications of short-chain fatty acids have benefited diversion colitis and distal UC, whereas probiotics hold promise in the treatment of pouchitis.

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Crossref · 10.1016/s0889-8553(01)00022-x

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133 of 133 references verified0 citation errors · 0 not checkable

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Authors
Graham, T. O., & Kandil, H. M.
Affiliations
University of Pittsburgh Medical Center (US)
Venue
Gastroenterology Clinics of North America
Publisher
Elsevier BV
Published
2002-03
Volume
31
Issue
1
Pages
203-218
ISSN
0889-8553 (ISSN-L)
OpenAlex
W2149240884
Cited by
30
References
133
Citations by year
2021: 2 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 2 · 2014: 3 · 2012: 2
FWCI
0.19
Type
journal article
Language
en
Open access
closed
Locations
  • Gastroenterology Clinics of North America (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Keywords
inflammatory bowel disease, Crohn's disease, ulcerative colitis, nutritional therapy, dietary antigens, mucosal immunity, total parenteral nutrition, enteral nutrition, bowel rest, corticosteroids, remission induction, elemental diet, polymeric diet, fish oil, omega-3 fatty acids, short-chain fatty acids, topical application, probiotics, pouchitis, diversion colitis
MeSH terms
Diet, Humans, Nutrition Disorders, Inflammatory Bowel Diseases

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