Cited by 360Nicotinic Acetylcholine Receptors StudySmoking Behavior and CessationNeuroscience and Neuropharmacology Research

The DOI matches its Crossref record; 169 of the 169 references it cites were found in a registry or an index.

Nicotinic receptors in the brain. Links between molecular biology and behavior

Open access

Picciotto, M·2000·Neuropsychopharmacology

DOI 10.1016/s0893-133x(99)00146-3

Open this paper in CoChat — free account Open PDF

Abstract

Molecular cloning has elucidated the sequence of a family of acetylcholine receptor subunits that are activated by nicotine. Subsequent studies on the localization of individual subunits and the physiological properties of nicotinic subunit combinations in vitro, have led to identification of subunit compositions of nicotinic receptors that may function in vivo, as the native receptor. A particular challenge for the field has been to use these molecular data to determine which individual nicotinic receptor subtype is responsible for mediating each of the behavioral effects of nicotine. Human and animal studies have shown that nicotine is reinforcing and likely responsible for the addictive properties of tobacco. In addition, nicotine has been shown to have effects on locomotion, cognition, affect, and pain sensitivity. Recent studies combining the techniques of molecular biology, pharmacology, electrophysiology, and behavioral analysis to analyze knock out mice that lack individual subunits of the nicotinic acetylcholine receptor, have helped identify the role of specific nicotinic subunits in some of these complex behaviors. These studies could ultimately be useful in designing specific nicotinic receptor agonists and antagonists that may have uses in the clinic.

Integrity signals

Registry

Crossref · 10.1016/s0893-133x(99)00146-3

Cites

169 of 169 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Drugs of abuse: anatomy, pharmacology and function of reward pathways
Koob, G. F. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90060-j · Cited by 2,070
Stress and cognitive function
McEwen, B. S., & Sapolsky, R. M. (1995) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(95)80028-x · Cited by 1,889
Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium
Séguéla, P., Wadiche, J. I., Dineley‐Miller, K., Dani, J., & Jw, P. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-02-00596.1993 · Cited by 1,471
CENTRAL CHOLINERGIC SYSTEMS AND COGNITION
Everitt, B. J., & Robbins, T. W. (1997) · Annual Review of Psychology · doi:10.1146/annurev.psych.48.1.649 · Cited by 1,348
Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine
Picciotto, M. R., Zoli, M., Rimondini, R., Léna, C., Marubio, L. M., Pich, E. M., Fuxe, K., & Changeux, J.-P. (1998) · Nature · doi:10.1038/34413 · Cited by 1,320
Self-citation
Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus
Freedman, R., Coon, H., Myles-Worsley, M., Orr-Urtreger, A., Olincy, A., Davis, A., Polymeropoulos, M., Holik, J., Hopkins, J., Hoff, M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.2.587 · Cited by 1,141
Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors
McGehee, D. S., Heath, M. J. S., Gelber, S., Devay, P., & Role, L. W. (1995) · Science · doi:10.1126/science.7569895 · Cited by 1,070
The Diversity of Neuronal Nicotinic Acetylcholine Receptors
Sargent, P. B. (1993) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.16.030193.002155 · Cited by 1,052
Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat
Wada, E., Wada, K., Boulter, J., Deneris, E. S., Heinemann, S., Patrick, J., & Swanson, L. W. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902840212 · Cited by 1,044
Hippocampal synaptic transmission enhanced by low concentrations of nicotine
Gray, R. G. F., Rajan, A. S., Radcliffe, K. A., Yakehiro, M., & Dani, J. A. (1996) · Nature · doi:10.1038/383713a0 · Cited by 947

Show all 165 references

Sorted by citations

Items 201–300 of 360

The Availability of the α7-Nicotinic Acetylcholine Receptor in Early Identification of Vulnerable Atherosclerotic Plaques: A Study Using a Novel 18F-Label Radioligand PET
Wang, D., Yao, Y., Wang, S., Zhang, H., & He, Z. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.640037 · Cited by 14
Nicotinic Acetylcholine Receptors Expressed by Striatal Interneurons Inhibit Striatal Activity and Control Striatal-Dependent Behaviors
Abbondanza, A., Bas, I. R., Modrák, M., Čapek, M., Minich, J., Tyshkevich, A., Naser, S., Rangotis, R., Houdek, P., Sumová, A., et al. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1627-21.2022 · Cited by 14
Acción de la nicotina como antidepresivo y regulador del sueño en sujetos deprimidos
Vieyra-Reyes, P., Venebra-Muñoz, A., Rivas-Santiago, B. T., & García, F. G. (2009) · Revista de Neurología · doi:10.33588/rn.4912.2009158 · Cited by 13
The effect of varenicline on the development and expression of nicotine‐induced behavioral sensitization and cross‐sensitization in rats
Goutier, W., Kloeze, M. B., & McCreary, A. C. (2013) · Addiction Biology · doi:10.1111/adb.12108 · Cited by 15
The dendritically targeted protein Dendrin is induced by acute nicotine in cortical regions of adolescent rat brain
Schochet, T. L., Bremer, Q. Z., Brownfield, M. S., Kelley, A. E., & Landry, C. F. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06483.x · Cited by 14
Nicotine induces tyrosine hydroxylase plasticity in the neurodegenerating striatum
Urbanavicius, J., Ferreira, M., Costa, G., Abin‐Carriquiry, J. A., Wonnacott, S., & Dajas, F. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04560.x · Cited by 14
Nicotinic Acetylcholine Receptors
Lindstrom, J. M. (2010) · Wiley eBooks · doi:10.1002/9780470015902.a0000245.pub2 · Cited by 14
Neuropeptide CART prevents memory loss attributed to withdrawal of nicotine following chronic treatment in mice
Borkar, C. D., Sagarkar, S., Sakharkar, A. J., Subhedar, N. K., & Kokare, D. M. (2017) · Addiction Biology · doi:10.1111/adb.12579 · Cited by 13
Effects of bupropion on the reinstatement of nicotine-induced conditioned place preference by drug priming in rats
Budzyńska, B., & Grażyna, B. (2011) · Pharmacological Reports · doi:10.1016/s1734-1140(11)70502-3 · Cited by 13
The α-7 Nicotinic Receptor Positive Allosteric Modulator Alleviates Lipopolysaccharide Induced Depressive-like Behavior by Regulating Microglial Function, Trophic Factor, and Chloride Transporters in Mice
Alzarea, S. I., Khan, A., Ronan, P. J., Lutfy, K., & Rahman, S. (2024) · Brain Sciences · doi:10.3390/brainsci14030290 · Cited by 12
Relationship between measures of inhibitory processes in patients with schizophrenia: Role of substance abuse disorders
Barba, R. J., Morales‐Muñoz, I., del Manzano, B. Á., Fernández‐Guinea, S., Caballero, M. I. I., Martínez‐Gras, I., & Rubio, G. (2011) · Psychiatry Research · doi:10.1016/j.psychres.2011.06.002 · Cited by 12
The Potential Effect of Caffeine and Nicotine Co-administration against Aluminum-induced Alzheimer's disease in Rats
Ali, A. A., & Ahmed, H. I. (2016) · Journal of Alzheimer’s Disease & Parkinsonism · doi:10.4172/2161-0460.1000236 · Cited by 13
Traits and Biomarkers for Addiction Risk in Schizophrenia
Kozak, K., Barr, M. S., & George, T. P. (2017) · Current Addiction Reports · doi:10.1007/s40429-017-0130-6 · Cited by 12
Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice
Muldoon, P. P., Akinola, L. S., Schlosburg, J. E., Lichtman, A. H., Sim‐Selley, L. J., Mahadevan, A., Cravatt, B. F., & Damaj, M. I. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108170 · Cited by 12
Differential influences of (±) anatoxin-a on photolocomotor behavior and gene transcription in larval zebrafish and fathead minnows
Lovin, L. M., Kim, S., Taylor, R. B., Scarlett, K. R., Langan, L. M., Chambliss, C. K., Chatterjee, S., Scott, J. T., & Brooks, B. W. (2021) · Environmental Sciences Europe · doi:10.1186/s12302-021-00479-x · Cited by 12
Acetylcholine Receptor Structure
Lindstrom, J. M. (2003) · Humana Press eBooks · doi:10.1007/978-1-59259-341-5_2 · Cited by 15
Sites of Excitatory and Inhibitory Actions of Alcohols on Neuronal α2β4 Nicotinic Acetylcholine Receptors
Borghese, C. M., Henderson, L. A., Bleck, V., Trudell, J. R., & Harris, R. A. (2003) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.053710 · Cited by 12
Association between Emotional Exhaustion and Tobacco Consumption in Teachers
Portilla, A., Meza, M. F., & Lizana, P. A. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19052606 · Cited by 18
Role of α5-containing nicotinic receptors in neuropathic pain and response to nicotine
Xanthos, D. N., Beiersdorf, J., Thrun, A., Ianosi, B., Orr‐Urtreger, A., Huck, S., & Scholze, P. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.02.012 · Cited by 11
A computational lens on menopause-associated psychosis
Fisher, V., Ortiz, L. S., & Powers, A. R. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.906796 · Cited by 12
Cholinergic mechanisms in schizophrenia: Current concepts
Raedler, T. J., & Tandon, R. (2006) · Current Psychosis & Therapeutics Reports · doi:10.1007/bf02629410 · Cited by 11
Antagonism of muscarinic M1 receptors by dicyclomine inhibits the consolidation of morphine-associated contextual memory
Esmaeili, B., Basseda, Z., & Dehpour, A. R. (2008) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2008.02.003 · Cited by 11
Pharmacological Effects of Nicotine and Nicotinic Receptor Subtype Pharmacological Profiles
Lukas, R. J. (2006) · CRC Press eBooks · doi:10.1201/9781420005431.ch1 · Cited by 11
Smoking Hazards and Cessation
Benowitz, N. L., & Brunetta, P. G. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-4710-0.00040-7 · Cited by 11
Neurobiologic Basis of Nicotine Addiction and Psychostimulant Abuse: a Role for Neurotensin?
Fredrickson, P. A., Boules, M., Lin, S.-C., & Richelson, E. (2005) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2005.05.001 · Cited by 10
Virtual screening studies of Chinese medicine Coptidis Rhizoma as alpha7 nicotinic acetylcholine receptor agonists for treatment of Alzheimer’s disease
Li, X., Xu, Y., Zhang, Y., Meng, X., & Wang, P. (2015) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2015.01.021 · Cited by 10
A role for β2* nicotinic receptors in a model of local amyloid pathology induced in dentate gyrus
Lombardo, S., Catteau, J., Besson, M., & Maskos, U. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.06.005 · Cited by 10
Acetylcholine Receptor Structure
Luo, J., & Lindstrom, J. M. (2018) · Springer eBooks · doi:10.1007/978-3-319-73585-6_2 · Cited by 11
Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone
Novick, A. M., Duffy, K. A., Johnson, R. L., Sammel, M. D., Cao, W., Strasser, A. A., Sofuoglu, M., Kuzma, A., Loughead, J., Morrow, A. L., et al. (2022) · Biology of Sex Differences · doi:10.1186/s13293-022-00472-w · Cited by 9
Ending tobacco-caused mortality and morbidity: the case for performance standards for tobacco products
Hatsukami, D. K. (2013) · Tobacco Control · doi:10.1136/tobaccocontrol-2012-050785 · Cited by 9
Nicotine restores monoamine neurotransmitter changes in the cortex and hippocampus of reserpinized rats as a model of depression.
Khadrawy, Y. A., El-Shamy, K. A., & Mohamed, S. (2011) · PubMed · Cited by 9
CHRNA5 rs16969968 and CHRNA3 rs578776 polymorphisms are associated with multiple nicotine dependence phenotypes in Bangladeshi smokers
Chaity, N. I., & Apu, M. N. H. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e09947 · Cited by 8
Behavioral, biochemical, and endocrine responses of zebrafish to 30-min exposure with environmentally relevant concentrations of imidacloprid-based insecticide
Soares, S. M., Fortuna, M., Freddo, N., Varela, A. C. C., Pompermaier, A., Mozzato, M. T., Costa, V. C., Tamagno, W. A., Rossato‐Grando, L. G., & Barcellos, L. J. G. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-27667-x · Cited by 8
α7 and β2* nicotinic receptors control monoamine-mediated locomotor response
Villégier, A., Salomon, L., Granon, S., Champtiaux, N., Changeux, J., & Tassin, J. (2010) · Neuroreport · doi:10.1097/wnr.0b013e328340536a · Cited by 8
Depression, Anxiety and Stress among Obese Patients with Chronic Illnesses: Prevalence and Associated Factors in North East Malaysia
Hassan, R., Zulkifli, M. M., Ahmad, I., & Yusoff, S. S. M. (2019) · Bangladesh Journal of Medical Science · doi:10.3329/bjms.v18i2.40694 · Cited by 7
Evaluation of the distribution of nicotine intravenous injection: an adult autopsy case report with a review of literature
Aoki, Y., Ikeda, T., Tani, N., Shida, A., Oritani, S., & Ishikawa, T. (2019) · International Journal of Legal Medicine · doi:10.1007/s00414-019-02035-y · Cited by 8
Interactions between the Nicotinic and Endocannabinoid Receptors at the Plasma Membrane
Vallés, A. S., & Barrantes, F. J. (2022) · Membranes · doi:10.3390/membranes12080812 · Cited by 7
Increased high-affinity nicotinic receptor-binding in rats exposed to lead during development
Jett, D. A., Beckles, R. A., Navoa, R. V., & McLemore, G. L. (2002) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(02)00314-8 · Cited by 8
Efficacy of nicotine administration on obsessions and compulsions in OCD: a systematic review
Piacentino, D., Maraone, A., Roselli, V., Berardelli, I., Biondi, M., Kotzalidis, G. D., & Pasquini, M. (2020) · Annals of General Psychiatry · doi:10.1186/s12991-020-00309-z · Cited by 8
Nicotine Discrimination in Humans
Perkins, K. A. (2011) · Wiley eBooks · doi:10.1002/9781118023150.ch15 · Cited by 8
Antisense inhibition of neuronal nicotinic receptors in the tobacco‐feeding insect, Manduca sexta
Fickbohm, D., & Trimmer, B. A. (2003) · Archives of Insect Biochemistry and Physiology · doi:10.1002/arch.10100 · Cited by 8
Cannabidiol Modulation of Nicotine‐Induced Toxicity: Assessing Effects on Behavior, Brain‐Derived Neurotrophic Factor, and Oxidative Stress in C57BL /6 Male Mice
Mesiakaris, K., Atsopardi, Κ., Lagoumintzis, G., Margarity, M., & Poulas, K. A. (2024) · Journal of Neuroscience Research · doi:10.1002/jnr.25384 · Cited by 7
Neurobiological associations between smoking and internalizing disorders
Lima, T. M. F., Castaldelli-Maia, J. M., Apter, G., & Leopoldo, K. (2023) · International Review of Psychiatry · doi:10.1080/09540261.2023.2252907 · Cited by 9
Cortical α4β2-nicotinic acetylcholine receptors and cognitive decline in Parkinson's disease
Mills, K. A., Kuwabara, H., Du, Y., Gómez, G., Motley, C., Skorobogatova, Y., Spiro, E., Coughlin, J. M., Lesniak, W. G., Brandt, J., et al. (2025) · Journal of Parkinson s Disease · doi:10.1177/1877718x241313373 · Cited by 7
Psychiatric Predisposition to Autonomic and Abnormal Perception Side-Effects of Ziconotide: A Case Series Study
Poli, P., & Ciaramella, A. (2011) · Neuromodulation Technology at the Neural Interface · doi:10.1111/j.1525-1403.2011.00334.x · Cited by 7
Impaired cognition and attention in adults: pharmacological management strategies
Allain, H., Akwa, Y., Lacomblez, L., Lieury, A., & Bentué‐Ferrer, D. (2007) · Neuropsychiatric Disease and Treatment · doi:10.2147/nedt.2007.3.1.103 · Cited by 8
The potential of neuronal nicotinic acetylcholine receptor agonists for treating CNS conditions
Decker, M. W., Gopalakrishnan, M., & Meyer, M. D. (2008) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.3.9.1027 · Cited by 7
Involvement of the α4β2 nicotinic receptor subtype in nicotine-induced attenuation of Δ9-THC cerebellar ataxia: Role of cerebellar nitric oxide
Smith, A. D., & Dar, M. S. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.12.013 · Cited by 7
Parallel synthesis of a series of potentially brain penetrant aminoalkyl benzoimidazoles
Micco, I., Nencini, A., Quinn, J., Bothmann, H., Ghiron, C., Padova, A., & Papini, S. (2007) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2007.11.068 · Cited by 7
Advances in Drug Discovery and Development in Geriatric Psychiatry
Conley, A. C., & NEWHOUSE, P. A. (2018) · Current Psychiatry Reports · doi:10.1007/s11920-018-0871-5 · Cited by 8
Alterations in Phase-Related Prefrontal Activation During Cognitive Tasks and Nicotinic α4β2 Receptor Availability in Alzheimer’s Disease
Oboshi, Y., Kikuchi, M., Terada, T., Yoshikawa, E., Bunai, T., & Ouchi, Y. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-151165 · Cited by 6
Physiological and pathological processes of synaptic plasticity and memory in drug discovery: Do not forget the dose-response curve
Prickaerts, J., van Goethem, N. P., Gulisano, W., Argyrousi, E. K., Palmeri, A., & Puzzo, D. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.05.058 · Cited by 6
Nicotinic Signaling in Development
Fernandes, C., Lozada, A. F., & Berg, D. K. (2014) · The Receptors · doi:10.1007/978-1-4939-1167-7_6 · Cited by 6
Nicotine effect on mismatch negativity in smoking and nonsmoking patients with schizophrenia
Inami, R., & Kirino, E. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.01.002 · Cited by 6
Involvement of neuronal nicotinic receptor in psychiatric disorders.
Suemaru, K., Araki, H., & Gomita, Y. (2002) · Folia Pharmacologica Japonica · doi:10.1254/fpj.119.295 · Cited by 6
Interactions between CRF and acetylcholine in the modulation of cognitive behaviour
Warnock, G., Prickaerts, J., & Steckler, T. (2006) · Birkhäuser Basel eBooks · doi:10.1007/978-3-7643-7772-4_3 · Cited by 6
Ethanol Consumption Produces Changes in Behavior and on Hippocampal α7 and α4β2 Nicotinic Receptors
Robles, N., & Sabrià, J. (2006) · Journal of Molecular Neuroscience · doi:10.1385/jmn:30:1:119 · Cited by 6
Surface and intracellular nicotinic receptors expressed in intact adrenal chromaffin cells: direct measurements using [3H]epibatidine
Free, R. B., & McKay, D. B. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02551-4 · Cited by 6
Depression Predicts Smoking among Adolescent Girls but Not among Boys
Fröjd, S. A. (2013) · Journal of Child and Adolescent Behaviour · doi:10.4172/2375-4494.1000114 · Cited by 6
Design and synthesis of new agents for neuronal nicotinic acetylcholine receptor (nAChRs) imaging
Liu, Y., Yu, H., Zhao, L., & Zhang, H. (2012) · Nuclear Medicine and Biology · doi:10.1016/j.nucmedbio.2012.09.005 · Cited by 5
Protective effects of mecamylamine and atropine against α4β2 nicotinic receptor expression and functional toxicity in paraoxon-treated rats
Mehrani, H. A., Asadi, B., & Golmanesh, L. (2008) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2008.05.003 · Cited by 5
Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors
Zapukhliak, O. S., Netsyk, O., Romanov, A., Maximyuk, O. P., Öz, M., Holmes, G. L., Krishtal, O., & Isaev, D. S. (2021) · PLoS ONE · doi:10.1371/journal.pone.0240074 · Cited by 4
Relationship between mood disorders and substance involvement and the shared genetic liabilities: A population-based study in Taiwan
Lai, R., Su, M., Lin, K., Chen, C., Pan, Y., Hsiao, P., Chen, P., Huang, Y., Wu, C., & Wang, S. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.10.141 · Cited by 5
(+) Anatoxin-a elicits differential survival, photolocomotor behavior, and gene expression in two alternative vertebrate models
Lovin, L. M., Langan, L. M., Scarlett, K. R., Taylor, R. B., Kim, S., Chambliss, C. K., Chatterjee, S., Scott, J. T., & Brooks, B. W. (2024) · Environment International · doi:10.1016/j.envint.2024.109045 · Cited by 4
Neuronal Nicotinic Receptors as New Targets for Amphetamine-Induced Oxidative Damage and Neurotoxicity
Pubill, D., Garcia-Ratés, S., Camarasa, J., & Escubedo, E. (2011) · Pharmaceuticals · doi:10.3390/ph4060822 · Cited by 5
Alzheimer's Disease
Veljkovic, E., Xia, W., Phillips, B. W., Wong, E. T., Ho, J., Oviedo, A., Hoeng, J., & Peitsch, M. C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812922-7.00002-0 · Cited by 4
The alpha-7 nicotinic acetylcholine receptor agonist GTS-21 does not affect food intake in rats
DiBrog, A. M., Kern, K. A., Mukherjee, A., Przybysz, J. T., & Mietlicki‐Baase, E. G. (2022) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2022.173444 · Cited by 4
Neurotransmitter Systems in Bipolar Disorder
Nakic, M., Krystal, J. H., & Bhagwagar, Z. (2010) · Wiley eBooks · doi:10.1002/9780470661277.ch16 · Cited by 4
Brain systems in cocaine abstinence-induced anxiety-like behavior in rodents: A review
Barbee, B. R., & Gourley, S. L. (2022) · Addiction Neuroscience · doi:10.1016/j.addicn.2022.100012 · Cited by 5
Nicotinic acetylcholine receptors in the brain
Barrantes, F. J. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-19088-9.00004-4 · Cited by 3
Simulations of Promising Indolizidine—α6-β2 Nicotinic Acetylcholine Receptor Complexes
Acquah, F. A., Paramel, M., Kuta, A., Hussaini, S. R., Wallace, D. R., & Mooers, B. H. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157934 · Cited by 3
Nicotiana tabacum L., Usos y Percepciones
Moreno-Coutiño, A. B., & Bello, B. C. (2012) · ETNOBIOLOGÍA · Cited by 3
Paying Attention to Your Acetylcholine, Part 2: The Function of Nicotinic Receptors
Stahl, S. M. (2000) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v61n0905 · Cited by 3
Discovery of a protein sequence in the N-terminal region of the human neuronal α7 nicotinic acetylcholine receptor involved in homomeric interactions.
Chio, C. L., Alberts, G. L., Im, W. B., Slightom, J. L., & Gill, G. S. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)01068-6 · Cited by 3
Novel Approaches for the Treatment of Schizophrenia
Rogers, B. N., & Schmidt, C. J. (2006) · Annual reports in medicinal chemistry · doi:10.1016/s0065-7743(06)41001-0 · Cited by 3
Screening of Attractants for Male Spodoptera frugiperda Based on the Interaction between Odorant-Binding Protein 20 and Host Volatiles
Yang, S., Yin, M., Yang, H.-H., An, J.-Z., Zhang, Y., & Li, X. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c05562 · Cited by 2
Identification of α7 Nicotinic Acetylcholine Receptor Agonists for their Assessment in Improving Cognition in Schizophrenia
Rogers, B. N., Jacobsen, E. J., O’Donnell, C. J., Shaffer, C. L., Walker, D. P., & Wishka, D. G. (2010) · Royal Society of Chemistry eBooks · doi:10.1039/9781849731980-00332 · Cited by 2
Investigating the role of nicotinic acetylcholine receptors in menthol's effects in mice
Akinola, L. S., Gonzales, J., Buzzi, B., Mathews, H. L., Papke, R. L., Stitzel, J. A., & Damaj, M. I. (2024) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2024.111262 · Cited by 2
Effect of Vernonia Cinerea Water Extract on the Protection of Liver Tissue in Chronic Nicotine-Treated Rats
Promputta, C., Anupunpisit, V., Anantasomboon, G., Palasoon, R., Wimoonchart, A., & Timklay, W. (2024) · Journal of Current Science and Technology · doi:10.59796/jcst.v14n3.2024.67 · Cited by 2
Depression Screening and Study of Associated Factors Among Elderly South Indian Patients in A Primary Care Setting
Brahmbhatt, K. R., Dâ€TMSouza, O., Yalaburgi, K. S., Hameed, S., Jayaram, S., & Kurulkar, P. V. (2014) · International journal of medical and health sciences · Cited by 2
Critical Role of Cannabinoid CB1 Receptors in Nicotine Reward and Addiction
Rezayof, A., & Hashemizadeh, S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800213-1.00015-8 · Cited by 2
Radiosynthesis and in-vivo evaluation of [125I]IBT: a single-photon emission computed tomography radiotracer for &agr;7-nicotinic acetylcholine receptor imaging
Wang, H., Wu, A.-Q., Liu, J., Xue, Q., Lu, X., Yin, L., Fang, Y., & Zhang, H.-B. (2017) · Nuclear medicine communications · doi:10.1097/mnm.0000000000000700 · Cited by 2
WO03/062224 is an in vivo selective agonist at nicotinic β4 receptors
Greenhalgh, C. E., Smith, J. R., & Clifton, P. G. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2008.06.005 · Cited by 2
Delirium and Nicotine Withdrawal
Kataria, D. K., Ankit, G., Tiwari, S., & Kukreti, P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813035-3.00028-9 · Cited by 2
Exacerbation of Psychosis: A Case of Possible Varenicline-Mediated Effects in an Intellectually Disabled Adult
Brahm, N. C., & Fast, G. A. (2008) · Clinical Schizophrenia & Related Psychoses · doi:10.3371/csrp.2.3.7 · Cited by 2
An Investigation of CYP2B in Rat Brain: Regulation and Role in Drug and Toxin Response
Khokhar, J. Y. (2012) · TSpace (University of Toronto) · Cited by 2
Involvement of α7 nicotinic acetylcholine receptor-signaling in social behavior impairments in the stressed mice
Uchida, M., Kano, M., Ozaki, N., Yoshimi, A., & Noda, Y. (2026) · Neurochemistry International · doi:10.1016/j.neuint.2026.106121 · Cited by 1
Eye movements and schizophrenia risk genes. Associations of the putative schizophrenia risk genes COMT and NRG-1 with smooth pursuit and antisaccade eye movement endophenotypes in schizophrenia patients and healthy controls drawn from the homogenous Icelandic population
Haraldsson, M. H. (2010) · Cited by 1
The Cannabinoid System in Nicotine Dependence and Withdrawal
McIlwain, M., Minassian, A., & Perry, W. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802574-1.00009-0 · Cited by 1
Acetylcholine Receptor Structure
Lindstrom, J. M. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-156-7_2 · Cited by 1
A preliminary investigation of tobacco co-use on endocannabinoid activity in people with cannabis use
Rabin, R. A., Farrugia, J., Ramesh, R. G., Mizrahi, R., & Rusjan, P. (2025) · Drug and Alcohol Dependence Reports · doi:10.1016/j.dadr.2025.100369 · Cited by 1
Treating the Cognitive Deficits of Schizophrenia
Rogers, B. N., & Gray, D. L. (2012) · Royal Society of Chemistry eBooks · doi:10.1039/9781849734943-00123 · Cited by 1
The Relationship Between Mood, Stress, and Tobacco Smoking
Walderhaug, E., Cosgrove, K., Bhagwagar, Z., & Neumeister, A. (2010) · Springer eBooks · doi:10.1007/978-1-4419-6373-4_10 · Cited by 1
Changes in Affect Following Smoking Cessation in Depressed Smokers
Mathew, A. R. (2013) · Cited by 1
Nicotine
Buchhalter, A. R., Fant, R. V., & Henningfield, J. E. (2007) · Wiley eBooks · doi:10.1002/9780470101001.hcn037 · Cited by 1
Special Topics
(2006) · CRC Press eBooks · doi:10.1201/9781420005431.pt5 · Cited by 1
Basic Science
(2006) · CRC Press eBooks · doi:10.1201/9781420005431.pt1 · Cited by 1
Nicotinic Acetylcholine Receptors
Lindstrom, J. M. (2002) · Encyclopedia of Life Sciences · doi:10.1038/npg.els.0000245 · Cited by 1
Cholinergic Mechanisms in Schizophrenia
Raedler, T. J., & Freedman, R. (2009) · Springer eBooks · doi:10.1007/978-0-387-30410-6_2 · Cited by 1
Efeito da nicotina na ativação do fator de transcrição NF-B no sistema nervoso central na vigência de estímulo inflamatório induzido por lipopolissacarídeo (LPS)
Mendes, C. C. C. (2009) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2009.tde-28082009-105421

Authors: Picciotto, M.
Affiliations: Yale University (US)
Corresponding author: Picciotto, M
ORCID: Picciotto, M
Venue: Neuropsychopharmacology
Publisher: Springer Science and Business Media LLC
Published: 2000-05
Volume: 22
Issue: 5
Pages: 451-465
ISSN: 0893-133X (ISSN-L)
DOI: 10.1016/s0893-133x(99)00146-3
OpenAlex: W2091673195
Cited by: 354
References: 165
Citations by year: 2026: 5 · 2025: 5 · 2024: 8 · 2023: 7 · 2022: 12 · 2021: 10 · 2020: 4 · 2019: 7 · 2018: 10 · 2017: 9 · 2016: 16 · 2015: 14 · 2014: 13 · 2013: 15 · 2012: 10
FWCI: 1.26
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Neuropsychopharmacology (publishedVersion)
PubMed (publishedVersion)
Figshare (submittedVersion, cc-by)
Funders: National Institutes of Health (DA10455)
National Institute on Drug Abuse (DA-00167, DA 10455, DA-07290, K12DA000167)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: nicotinic acetylcholine receptors, nicotinic receptor subunits, nicotine, nicotine dependence, tobacco, receptor knockout mice, locomotion, cognition, affect, pain sensitivity
MeSH terms: Animals, Behavior, Humans, Models, Neurological, Molecular Biology, Receptors, Nicotinic, Mice, Knockout, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nicotinic receptors in the brain. Links between molecular biology and behavior

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks