Effect of obesity on endothelium-dependent, nitric oxide-mediated vasodilation in normotensive individuals and patients with essential hypertension

Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge

Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423 · see citing works

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502 · see citing works

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Hotamisligil, G. S., Arner, P., Caro, J. F., Atkinson, R. L., & Spiegelman, B. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117936 · Cited by 3,543 · see citing works

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Hotamisligil, G. S., Peraldi, P., Budavari, A., Ellis, R., White, M. F., & Spiegelman, B. M. (1996) · Science · doi:10.1126/science.271.5249.665 · Cited by 2,630 · see citing works

Abnormal Endothelium-Dependent Vascular Relaxation in Patients with Essential Hypertension

Panza, J. A., Quyyumi, A. A., Brush, J. E., & Epstein, S. E. (1990) · New England Journal of Medicine · doi:10.1056/nejm199007053230105 · Cited by 2,366 · see citing works

Insulin Resistance in Essential Hypertension

Ferrannini, E., Buzzigoli, G., Bonadonna, R., Giorico, M. A., Oleggini, M., Graziadei, L., Pedrinelli, R., Brandi, L., & Bevilacqua, S. (1987) · New England Journal of Medicine · doi:10.1056/nejm198708063170605 · Cited by 2,344 · see citing works

Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. Intersalt Cooperative Research Group.

(1988) · BMJ · doi:10.1136/bmj.297.6644.319 · Cited by 2,213 · see citing works

Endothelium‐derived relaxing and contracting factors

Furchgott, R. F., & Vanhoutte, P. M. (1989) · The FASEB Journal · doi:10.1096/fasebj.3.9.2545495 · Cited by 2,007 · see citing works

Role of endothelium-derived nitric oxide in the regulation of blood pressure.

Rees, D. D., Palmer, R. M. J., & Moncada, S. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.9.3375 · Cited by 1,827 · see citing works

Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

Steinberg, H. O., Chaker, H., Leaming, R., Johnson, A., Brechtel, G., & Baron, A. D. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118709 · Cited by 1,687 · see citing works

Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man

Vallance, P., Collier, J., & Moncada, S. (1989) · The Lancet · doi:10.1016/s0140-6736(89)91013-1 · Cited by 1,590 · see citing works

Hyperinsulinemia. A link between hypertension obesity and glucose intolerance.

Modan, M., Halkin, H., Almog, S., Lusky, A., Eshkol, A., Shefi, M., Shitrit, A., & Fuchs, Z. (1985) · Journal of Clinical Investigation · doi:10.1172/jci111776 · Cited by 1,465 · see citing works

Intersalt: An international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion

Rose, G. A., Stamler, J., Stamler, R., Elliott, P., Marmot, M. G., Pyörälä, K., Kesteloot, H., Joossens, J. V., Hansson, L. ‐., Mancia, G., et al. (1988) · Cited by 1,281 · see citing works

Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus.

Ting, H. H., Timimi, F. K., Boles, K., Creager, S. J., Ganz, P., & Creager, M. A. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118394 · Cited by 869 · see citing works

Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins

Kugiyama, K., Kerns, S. A., Morrisett, J. D., Roberts, R., & Henry, P. D. (1990) · Nature · doi:10.1038/344160a0 · Cited by 858 · see citing works

The Relation of Adiposity to Blood Pressure and Development of Hypertension

Kannel, W. B., BRAND, N., SKINNER, J. J., Dawber, T. R., & MCNAMARA, P. M. (1967) · Annals of Internal Medicine · doi:10.7326/0003-4819-67-1-48 · Cited by 815 · see citing works

Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Blunted response in essential hypertension.

Linder, L., Kiowski, W., Bühler, F. R., & Lüscher, T. F. (1990) · Circulation · doi:10.1161/01.cir.81.6.1762 · Cited by 797 · see citing works

Aging and Endothelial Function in Normotensive Subjects and Patients With Essential Hypertension

Taddei, S., Virdis, A., Mattei, P., Ghiadoni, L., Gennari, A., Fasolo, C. B., Sudano, I., & Salvetti, A. (1995) · Circulation · doi:10.1161/01.cir.91.7.1981 · Cited by 710 · see citing works

Regular Aerobic Exercise Augments Endothelium-Dependent Vascular Relaxation in Normotensive As Well As Hypertensive Subjects

Higashi, Y., Sasaki, S., Kurisu, S., Yoshimizu, A., Sasaki, N., Matsuura, H., Kajiyama, G., & Oshima, T. (1999) · Circulation · doi:10.1161/01.cir.100.11.1194 · Cited by 552 · see citing works

Inactivation of endothelial derived relaxing factor by oxidized lipoproteins.

Chin, J. H., Azhar, S., & Hoffman, B. B. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115549 · Cited by 449 · see citing works

Racial Differences in the Relation between Blood Pressure and Insulin Resistance

Saad, M. F., Lillioja, S., Nyomba, B. L., Castillo, C., Ferraro, R., De Gregorio, M., Ravussin, E., Knowler, W. C., Bennett, P. H., Howard, B. V., et al. (1991) · New England Journal of Medicine · doi:10.1056/nejm199103143241105 · Cited by 421 · see citing works

Hypertension and left ventricular hypertrophy are associated with impaired endothelium-mediated relaxation in human coronary resistance vessels.

Treasure, C. B., Klein, J. L., Vita, J. A., Manoukian, S. V., Renwick, G. H., Selwyn, A. P., Ganz, P., & Alexander, R. W. (1993) · Circulation · doi:10.1161/01.cir.87.1.86 · Cited by 392 · see citing works

The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients.

Casino, P. R., Kilcoyne, C. M., Quyyumi, A. A., Hoeg, J. M., & Panza, J. A. (1993) · Circulation · doi:10.1161/01.cir.88.6.2541 · Cited by 366 · see citing works

Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure.

Baron, A., Brechtel, G., Johnson, A., & Hardin, D. S. (1993) · Hypertension · doi:10.1161/01.hyp.21.2.129 · Cited by 361 · see citing works

Insulin and blood pressure in obesity.

Lucas, C. P., Estigarribia, J., Darga, L. L., & Reaven, G. M. (1985) · Hypertension · doi:10.1161/01.hyp.7.5.702 · Cited by 273 · see citing works

Elaboration of Type-1 Plasminogen Activator Inhibitor From Adipocytes

Lundgren, C. H., Brown, S. L., Nordt, T. K., Sobel, B. E., & Fujii, S. (1996) · Circulation · doi:10.1161/01.cir.93.1.106 · Cited by 224 · see citing works

Pathophysiological correlates of increased serum tumor necrosis factor in patients with congestive heart failure. Relation to nitric oxide-dependent vasodilation in the forearm circulation.

Katz, S. D., Rao, R., Berman, J. W., Schwarz, M., Demopoulos, L. A., Bijou, R., & LeJemtel, T. H. (1994) · Circulation · doi:10.1161/01.cir.90.1.12 · Cited by 217 · see citing works

l -Arginine Induces Nitric Oxide–Dependent Vasodilation in Patients With Critical Limb Ischemia

Bode‐Böger, S. M., Böger, R. H., Alfke, H., Heinzel, D., Tsikas, D., Creutzig, A., Alexander, K., & Frölich, J. C. (1996) · Circulation · doi:10.1161/01.cir.93.1.85 · Cited by 196 · see citing works

Comparison of Effects of Angiotensin I– Converting Enzyme Inhibition and β-Blockade for 2 Years on Function of Small Arteries From Hypertensive Patients

Schiffrin, E. L., & Deng, L.-Y. (1995) · Hypertension · doi:10.1161/01.hyp.25.4.699 · Cited by 192 · see citing works

Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men.

Castillo, C., Bogardus, C., Bergman, R. N., Thuillez, P., & Lillioja, S. (1994) · Journal of Clinical Investigation · doi:10.1172/jci116932 · Cited by 154 · see citing works

Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity.

Laine, H. K., Yki‐Järvinen, H., Kirvelä, O., Tolvanen, T., Raitakari, M., Solin, O. H., Haaparanta‐Solin, M., Knuuti, J. M., & Nuutila, P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1065 · Cited by 133 · see citing works

Anti-EDRF effect of tumor necrosis factor in isolated, perfused cat carotid arteries

Aoki, N., Siegfried, M. R., & Lefer, A. M. (1989) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1989.256.5.h1509 · Cited by 121 · see citing works

Effects of l -Arginine Infusion on Renal Hemodynamics in Patients With Mild Essential Hypertension

Higashi, Y., Oshima, T., Ozono, R., Watanabe, M., Matsuura, H., & Kajiyama, G. (1995) · Hypertension · doi:10.1161/01.hyp.25.4.898 · Cited by 104 · see citing works

Aging and Severity of Hypertension Attenuate Endothelium-Dependent Renal Vascular Relaxation in Humans

Higashi, Y., Oshima, T., Ozono, R., Matsuura, H., & Kajiyama, G. (1997) · Hypertension · doi:10.1161/01.hyp.30.2.252 · Cited by 102 · see citing works

Regulation of local tissue-type plasminogen activator release by endothelium-dependent and endothelium-independent agonists in human vasculature

Stein, C. M., Brown, N. L., Vaughan, D. E., Lang, C. C., & Wood, A. J. J. (1998) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(98)00210-1 · Cited by 85 · see citing works

Obesity-associated hypertension. Hyperinsulinemia and renal mechanisms.

Hall, J. E., Brands, M. W., Hildebrandt, D. A., & Mizelle, H. L. (1992) · Hypertension · doi:10.1161/01.hyp.19.1_suppl.i45 · Cited by 76 · see citing works

Vascular nitric oxide: Beyond eNOS

Zhao, Y., Vanhoutte, P. M., & Leung, S. W. S. (2015) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2015.09.002 · Cited by 823 · see citing works

Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension*

Rocca, H. B., Cockcroft, J., Deanfield, J. E., Donald, A. E., Ferrannini, E., Halcox, J., Kiowski, W., ̈scher, T. F. L., Mancia, G., Natali, A., et al. (2005) · Journal of Hypertension · doi:10.1097/00004872-200502000-00001 · Cited by 749 · see citing works

Obesity, Sleep Apnea, and Hypertension

Wolk, R., Shamsuzzaman, A. S. M., & Somers, V. K. (2003) · Hypertension · doi:10.1161/01.hyp.0000101686.98973.a3 · Cited by 532 · see citing works

Metabolic syndrome: Definition, pathophysiology, and mechanisms

Miranda, P. J., DeFronzo, R. A., Califf, R. M., & Guyton, J. R. (2005) · American Heart Journal · doi:10.1016/j.ahj.2004.07.013 · Cited by 480 · see citing works

Hemostasis, endothelial stress, inflammation, and the metabolic syndrome

Grandl, G., & Wolfrum, C. (2017) · Seminars in Immunopathology · doi:10.1007/s00281-017-0666-5 · Cited by 344 · see citing works

Regulation of obesity and insulin resistance by nitric oxide

Sansbury, B. E., & Hill, B. G. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.05.016 · Cited by 274 · see citing works

Plasminogen activator inhibitor-1: a common denominator in obesity, diabetes and cardiovascular disease

Taeye, B. M. D., Smith, L. H., & Vaughan, D. E. (2005) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2005.01.007 · Cited by 204 · see citing works

Emerging Role of Nitric Oxide and Heat Shock Proteins in Insulin Resistance

Molina, M. N., Ferder, L., & Manucha, W. A. (2015) · Current Hypertension Reports · doi:10.1007/s11906-015-0615-4 · Cited by 200 · see citing works

Endothelial Dysfunction: From Molecular Mechanisms to Measurement, Clinical Implications, and Therapeutic Opportunities

Brocq, M. L. L., Leslie, S. J., Milliken, P. H., & Megson, I. L. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.2013 · Cited by 190 · see citing works

Mechanisms of endothelial dysfunction in obesity.

Avogaro, A., & de Kreutzenberg, S. V. (2005) · Clinica Chimica Acta · doi:10.1016/j.cccn.2005.04.020 · Cited by 188 · see citing works

Retinal Vessel Diameters and Obesity: A Population‐Based Study in Older Persons

Wang, J. J., Taylor, B., Wong, T. Y., Chua, B., Rochtchina, E., Klein, R., & Mitchell, P. (2006) · Obesity · doi:10.1038/oby.2006.27 · Cited by 171 · see citing works

Determination of a reference value for NG, NG‐dimethyl‐L‐arginine in 500 subjects

Schulze, F., Maas, R., Freese, R., Schwedhelm, E., Silberhorn, E., & Böger, R. H. (2005) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2005.01561.x · Cited by 154 · see citing works

ED2: Erectile Dysfunction = Endothelial Dysfunction

Guay, A. T. (2007) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2007.03.007 · Cited by 145 · see citing works

Obesity increases prostanoid-mediated vasoconstriction and vascular thromboxane receptor gene expression

Traupe, T., Lang, M., Göettsch, W., Münter, K., Morawietz, H., Vetter, W., & Barton, M. (2002) · Journal of Hypertension · doi:10.1097/00004872-200211000-00024 · Cited by 134 · see citing works

Exercise training improves aortic endothelium-dependent vasorelaxation and determinants of nitric oxide bioavailability in spontaneously hypertensive rats

Graham, D. A., & Rush, J. W. E. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01252.2003 · Cited by 131 · see citing works

Inflammatory Aspects of Sleep Apnea and Their Cardiovascular Consequences

Kasasbeh, E. S., Chi, D. S., & Krishnaswamy, G. A. (2006) · Southern Medical Journal · doi:10.1097/01.smj.0000197705.99639.50 · Cited by 120 · see citing works

Prevalence of cardiovascular risk factors in erectile dysfunction.

Walczak, M. K., Lokhandwala, N., Hodge, M. B., & Guay, A. T. (2002) · PubMed · Cited by 120 · see citing works

Obesity reduces the bioavailability of nitric oxide in juveniles

Gruber, H.-J., Mayer, C., Mangge, H., Fauler, G., Grandits, N., & Wilders-Truschnig, M. (2008) · International Journal of Obesity · doi:10.1038/sj.ijo.0803795 · Cited by 119 · see citing works

Exercise rescues obese mothers’ insulin sensitivity, placental hypoxia and male offspring insulin sensitivity

Fernandez-Twinn, D. S., Gascoin, G., Musial, B., Carr, S., Duque-Guimaraes, D., Blackmore, H. L., Alfaradhi, M. Z., Loche, E., Sferruzzi-Perri, A. N., Fowden, A. L., et al. (2017) · Scientific Reports · doi:10.1038/srep44650 · Cited by 115 · see citing works

Obesity-associated activation of angiotensin and endothelin in the cardiovascular system

Barton, M., Carmona, R., Ortmann, J., Krieger, J. E., & Traupe, T. (2003) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(02)00307-2 · Cited by 113 · see citing works

The vital role for nitric oxide in intraocular pressure homeostasis

Reina‐Torres, E., Ieso, M. L. D., Pasquale, L. R., Madekurozwa, M., Sherwood, J. M., Overby, D. R., & Stamer, W. D. (2020) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100922 · Cited by 108 · see citing works

Weight Loss Reduces Circulating Asymmetrical Dimethylarginine Concentrations in Morbidly Obese Women

Krzyżanowska, K., Mittermayer, F., Kopp, H.-P., Wolzt, M., & Schernthaner, G. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0672 · Cited by 90 · see citing works

Low body mass index is a risk factor forimpaired endothelium-dependent vasodilation in humans: role of nitric oxide and oxidative stress

Higashi, Y., Sasaki, S., Nakagawa, K., Kimura, M., Noma, K., Sasaki, S., Hara, K., Matsuura, H., Goto, C., Oshima, T., et al. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(03)00630-2 · Cited by 84 · see citing works

Obesity‐related cardiovascular disease: implications of obstructive sleep apnea

Wolk, R. A., & Somers, V. K. (2005) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2005.00508.x · Cited by 77 · see citing works

Small lipid‐binding proteins in regulating endothelial and vascular functions: focusing on adipocyte fatty acid binding protein and lipocalin‐2

Wang, Y. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01528.x · Cited by 75 · see citing works

Diabetes, obesity, and erectile dysfunction

Tamler, R. (2009) · Gender Medicine · doi:10.1016/j.genm.2008.12.003 · Cited by 72 · see citing works

Lowering of LDL Cholesterol Rather Than Moderate Weight Loss Improves Endothelium-Dependent Vasodilatation in Obese Women With Previous Gestational Diabetes

Bergholm, R., Tiikkainen, M., Vehkavaara, S., Tamminen, M., Teramo, K. A., Rissanen, A., & Yki‐Järvinen, H. (2003) · Diabetes Care · doi:10.2337/diacare.26.6.1667 · Cited by 70 · see citing works

Visceral obesity is characterized by impaired nitric oxide-independent vasodilation

de Kreutzenberg, S. V. (2003) · European Heart Journal · doi:10.1016/s0195-668x(03)00206-9 · Cited by 70 · see citing works

Mitochondrial involvement in skeletal muscle insulin resistance: A case of imbalanced bioenergetics

Affourtit, C. (2016) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2016.07.008 · Cited by 67 · see citing works

Prevalence of diabetes and obesity in association with prematurity and growth restriction

Kopec, G. L., Shekhawat, P., & Mhanna, M. J. (2017) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s115890 · Cited by 66 · see citing works

Obesity impairs vascular relaxation in human subjects: hyperglycemia exaggerates adrenergic vasoconstriction

Sivitz, W. I., Wayson, S. M., Bayless, M., Sinkey, C. A., & Haynes, W. G. (2007) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2005.12.003 · Cited by 59 · see citing works

Assessment of Inflammatory and Oxidative Biomarkers in Obesity and Their Associations with Body Mass Index

Piva, S. J., Tatsch, E., de Carvalho, J. A. M., Bochi, G. V., Kober, H., Duarte, T., Duarte, M. M. M. F., da Cruz, I. B. M., Moretto, M. B., & Moresco, R. N. (2012) · Inflammation · doi:10.1007/s10753-012-9538-2 · Cited by 53 · see citing works

Endurance Training Enhances Vasodilation Induced by Nitric Oxide in Human Skin

Boegli, Y., Gremion, G., Golay, S., Kübli, S., Liaudet, L., Leyvraz, P., Waeber, B., & Feihl, F. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12518.x · Cited by 50 · see citing works

Regulation of Muscle Blood Flow in Obesity

Hodnett, B. L., & Hester, R. L. (2007) · Microcirculation · doi:10.1080/10739680701282143 · Cited by 46 · see citing works

The contribution of different adipose tissue depots to plasma plasminogen activator inhibitor-1 (PAI-1) levels

Barnard, S. A., Pieters, M., & de Lange, Z. (2016) · Blood Reviews · doi:10.1016/j.blre.2016.05.002 · Cited by 47 · see citing works

IMPACT OF OBESITY AND INSULIN RESISTANCE ON VASOMOTOR TONE: NITRIC OXIDE AND BEYOND

Stepp, D. W. (2006) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2006.04381.x · Cited by 44 · see citing works

Reduced constrictor reactivity balances impaired vasodilation in the mesenteric circulation of the obese Zucker rat

Romanko, O. P., & Stepp, D. W. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00213.2005 · Cited by 43 · see citing works

Vascular reactivity at rest and during exercise in middle-aged obese men: effects of short-term, low-intensity, exercise training

Vinet, A., Karpoff, L., Walther, G., Startun, A., Obert, P., Goret, L., Dauzat, M., & Pérez‐Martin, A. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.206 · Cited by 42 · see citing works

Obesity, Type 2 Diabetes, and the Metabolic Syndrome

Genser, L., Mariolo, J. R. C., Castagneto‐Gissey, L., Panagiotopoulos, S., & Rubino, F. (2016) · Surgical Clinics of North America · doi:10.1016/j.suc.2016.03.013 · Cited by 43 · see citing works

Renal functional reserve in obesity hypertension

Pecly, I. M. D., Genelhu, V. A., & Francischetti, E. A. (2006) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2006.01037.x · Cited by 42 · see citing works

Arterial compliance and endothelial function

Correia, M., & Haynes, W. G. (2007) · Current Diabetes Reports · doi:10.1007/s11892-007-0043-1 · Cited by 42 · see citing works

The Effect of Moxonidine on Endothelial Dysfunction in Metabolic Syndrome

Topal, E., Çıkım, A. S., Çıkım, K., Temel, İ., & Оздемир, Р. (2006) · American Journal of Cardiovascular Drugs · doi:10.2165/00129784-200606050-00007 · Cited by 40 · see citing works

Intraplatelet L-Arginine-Nitric Oxide Metabolic Pathway: From Discovery to Clinical Implications in Prevention and Treatment of Cardiovascular Disorders

Gawryś, J., Gajecki, D., Szahidewicz-Krupska, E., & Doroszko, A. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/1015908 · Cited by 40 · see citing works

Mechanisms of hypertension in obesity

López de Fez, C. M., Gaztelu, M. T., Rubio, T., & Castaño, A. (2008) · Anales del Sistema Sanitario de Navarra · doi:10.23938/assn.0475 · Cited by 38 · see citing works

Prolonged treatment with angiotensin 1–7 improves endothelial function in diet-induced obesity

Beyer, A. M., Guo, D.-F., & Rahmouni, K. (2013) · Journal of Hypertension · doi:10.1097/hjh.0b013e32835ecbe5 · Cited by 37 · see citing works

Role of NO/VASP Signaling Pathway against Obesity-Related Inflammation and Insulin Resistance

Kang, Y. M., Kim, F., & Lee, W. J. (2017) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2017.41.2.89 · Cited by 37 · see citing works

Endothelial function and its assessment

Felmeden, D. C., & Lip, G. Y. H. (2005) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.14.11.1319 · Cited by 35 · see citing works

Cardiovascular consequences of the obesity pandemic: need for action

Barton, M., & Furrer, J. (2003) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.12.11.1757 · Cited by 35 · see citing works

An Association Between Plasma Asymmetric Dimethylarginine and Membrane Fluidity of Erythrocytes in Hypertensive and Normotensive MenAn Electron Paramagnetic Resonance Investigation

Tsuda, K., & Nishio, I. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2005.04.007 · Cited by 34 · see citing works

The damaging duo: Obesity and excess dietary salt contribute to hypertension and cardiovascular disease

Watso, J. C., Fancher, I. S., Gomez, D. H., Hutchison, Z. J., Gutiérrez, O. M., & Robinson, A. T. (2023) · Obesity Reviews · doi:10.1111/obr.13589 · Cited by 38 · see citing works

Resistance Band Exercise Training Prevents the Progression of Metabolic Syndrome in Obese Postmenopausal Women

Son, W., & Park, J.-J. (2021) · Journal of Sports Science and Medicine · doi:10.52082/jssm.2021.291 · Cited by 34 · see citing works

Impairment of the vascular relaxation and differential expression of caveolin-1 of the aorta of diabetic +db/+db mice

Lam, T. Y., Seto, S. W., Lau, Y. M., Au, L. S., Kwan, Y. W., Ngai, S. M., & Tsui, S. K. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.07.003 · Cited by 32 · see citing works

Bariatric Surgery Normalizes Protein Glycoxidation and Nitrosative Stress in Morbidly Obese Patients

Choromańska, B., Myśliwiec, P., Łuba, M., Wojskowicz, P., Myśliwiec, H., Choromańska, K., Dadan, J., Żendzian‐Piotrowska, M., Zalewska, A., & Maciejczyk, M. (2020) · Antioxidants · doi:10.3390/antiox9111087 · Cited by 30 · see citing works

Effects of Acquired Obesity on Endothelial Function in Monozygotic Twins

Pietiläinen, K. H., Bergholm, R., Rissanen, A., Kaprio, J. A., Häkkinen, A., Sattar, N. A., & Yki‐Järvinen, H. (2006) · Obesity · doi:10.1038/oby.2006.96 · Cited by 28 · see citing works

Potential roles of Citrulline and watermelon extract on metabolic and inflammatory variables in diabetes mellitus, current evidence and future directions: A systematic review

Azizi, S., Mahdavi, R., Vaghef‐Mehrabany, E., Maleki, V., Karamzad, N., & Ebrahimi‐Mameghani, M. (2019) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.13190 · Cited by 30 · see citing works

TGF-β: The missing link in obesity-associated airway diseases?

Woo, J., Koziol‐White, C. J., Panettieri, R. A., & Jude, J. A. (2021) · Current Research in Pharmacology and Drug Discovery · doi:10.1016/j.crphar.2021.100016 · Cited by 28 · see citing works

Weight changes and obesity predict impaired resting and endothelium‐dependent myocardial blood flow in postmenopausal women

Martin, J. W., Briesmiester, K. A., Bargardi, A., Muzik, O., Mosca, L. J., & Duvernoy, C. S. (2005) · Clinical Cardiology · doi:10.1002/clc.4960280105 · Cited by 26 · see citing works

The impact of L‐citrulline supplementation on glucose homeostasis, lipid profile, and some inflammatory factors in overweight and obese patients with type 2 diabetes: A double‐blind randomized placebo‐controlled trial

Azizi, S., Mahdavi, R., Mobasseri, M., Aliasgharzadeh, S., Abbaszadeh, F., & Ebrahimi‐Mameghani, M. (2021) · Phytotherapy Research · doi:10.1002/ptr.6997 · Cited by 26 · see citing works

Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice

Sansbury, B. E., Bhatnagar, A., & Hill, B. G. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00453 · Cited by 24 · see citing works

Antiobesogenic Role of Endothelial Nitric Oxide Synthase

Sansbury, B. E., & Hill, B. G. (2014) · Vitamins and hormones · doi:10.1016/b978-0-12-800254-4.00013-1 · Cited by 25 · see citing works

Association between changes in systolic blood pressure and incident diabetes in a community-based cohort study in Korea

Lee, S. W., Kim, H. C., Lee, J. M., Yun, Y. M., Lee, J. Y., & Suh, I. (2017) · Hypertension Research · doi:10.1038/hr.2017.21 · Cited by 25 · see citing works

Potentiation of vascular oxidative stress and nitric oxide-mediated endothelial dysfunction by high-fat diet in a mouse model of estrogen deficiency and hyperandrogenemia

Javeshghani, D., Schiffrin, E. L., Sairam, M. R., & Touyz, R. M. (2009) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2009.07.002 · Cited by 24 · see citing works

Platelet aggregation, blood viscosity and serum lipids in hypertensive and obese children

Haszon, I., Papp, F., Kovács, J., Bors, M., Németh, I., Bereczki, C., & Túri, S. (2003) · European Journal of Pediatrics · doi:10.1007/s00431-003-1156-4 · Cited by 23 · see citing works

Health behaviors and endothelial function

Gordon, J. L., Lavoie, K., Arsenault, A., Ditto, B., & Bacon, S. (2007) · Journal of Behavioral Medicine · doi:10.1007/s10865-007-9129-0 · Cited by 23 · see citing works

The relative impact of different measures of adiposity on markers of early atherosclerosis

Stamatelopoulos, K., Lekakis, J. P., Vamvakou, G. D., Katsichti, P., Protogerou, A. D., Revela, I., Karatzi, K., Alevizaki, M. K., Zakopoulos, N., & Papamichael, C. M. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2006.07.098 · Cited by 23 · see citing works

Nitric Oxide Exerts Basal and Insulin-Dependent Anorexigenic Actions in POMC Hypothalamic Neurons

Wellhauser, L., Chalmers, J. A., & Belsham, D. D. (2016) · Molecular Endocrinology · doi:10.1210/me.2015-1275 · Cited by 22 · see citing works

Adiposity, physical activity, and risk of hypertension: prospective data from the population-based HUNT Study, Norway

Stenehjem, J. S., Hjerkind, K. V., & Nilsen, T. I. L. (2018) · Journal of Human Hypertension · doi:10.1038/s41371-018-0042-5 · Cited by 21 · see citing works

Basal Endothelial Nitric Oxide Release Is Preserved in Overweight and Obese Adults

DeSouza, C. A., Guilder, G. P. V., Greiner, J. J., Smith, D. T., Hoetzer, G. L., & Stauffer, B. L. (2005) · Obesity Research · doi:10.1038/oby.2005.157 · Cited by 22 · see citing works

Endothelial dysfunction precedes atherosclerotic lesions and platelet activation in high fat diet-induced prothrombotic state

Aoki, R., Ikarugi, H., Naemura, A., Ijiri, Y., Yamashita, T., & Yamamoto, J. (2005) · Thrombosis Research · doi:10.1016/j.thromres.2005.04.022 · Cited by 22 · see citing works

Assessment of endothelial function in the patient with erectile dysfunction: an opportunity for the urologist

Tamler, R., & Bar-Chama, N. C. (2008) · International Journal of Impotence Research · doi:10.1038/ijir.2008.13 · Cited by 20 · see citing works

Rapid onset vasodilatation is blunted in obese humans

Blain, G. M., Limberg, J. K., Mortensen, G., & Schrage, W. G. (2011) · Acta Physiologica · doi:10.1111/j.1748-1716.2011.02370.x · Cited by 19 · see citing works

Exercise and diet-induced weight loss attenuates oxidative stress related-coronary vasoconstriction in obese adolescents

Gao, Z., Novick, M. B., Muller, M. D., Williams, R. J., Spilk, S., Leuenberger, U. A., & Sinoway, L. I. (2012) · European Journal of Applied Physiology · doi:10.1007/s00421-012-2459-9 · Cited by 19 · see citing works

Factors associated with diabetes mellitus among adults: Findings from the Indonesian Family Life Survey-5

Alfaqeeh, M., Alfian, S. D., & Abdulah, R. (2024) · Endocrine and Metabolic Science · doi:10.1016/j.endmts.2024.100161 · Cited by 18 · see citing works

Stimulatory Effect of Leptin on Nitric Oxide Production Is Impaired in Dietary‐Induced Obesity

Bełtowski, J., Wójcicka, G., & Jamroz, A. (2003) · Obesity Research · doi:10.1038/oby.2003.209 · Cited by 18 · see citing works

Combining citrulline with atorvastatin preserves glucose homeostasis in a murine model of diet‐induced obesity

Capel, F., Chabrier, G., Pitois, E., Rigaudière, J., Plénier, S. L., Durand, C., Jouve, C., Bandt, J. P. D., Cynober, L., Moinard, C., et al. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13269 · Cited by 18 · see citing works

Obesity-induced impairment of endothelium-dependent vasodilation in Tunisian women

Miâdi-Messaoud, H., Chouchane, A., Abderrazek, E., Debbabi, H., Zaouali, M., Tabka, Z., & Jebria, A. B. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.231 · Cited by 17 · see citing works

Abnormally increased nitric oxide synthesis and increased endothelin‐1 in plasma in patients with obstructive sleep apnoea

Gjørup, P. H., Wessels, J., & Pedersen, E. B. (2008) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510701782382 · Cited by 15 · see citing works

YKL-40 is a novel biomarker for predicting hypertension incidence among prehypertensive subjects: A population-based nested case-control study in China

Xu, T., Zhong, C., Wang, A., Guo, Z., Bu, X., Zhou, Y., Tian, Y., Huangfu, X., Zhu, Z., & Zhang, Y. (2017) · Clinica Chimica Acta · doi:10.1016/j.cca.2017.08.003 · Cited by 14 · see citing works

Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women

Hašpicová, M., Milek, D., Šiklová, M., Wedellová, Z., Hejnová, J., Bajzová, M., Štich, V., & Polak, J. (2011) · Medical Science Monitor · doi:10.12659/msm.882048 · Cited by 13 · see citing works

Gender-based cardiometabolic risk evaluation in minority and non-minority men grading the evidence of non-traditional determinants of cardiovascular risk

Billups, K. L., Miner, M. M., Wierzbicki, A. S., & Jackson, G. (2010) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2010.02564.x · Cited by 13 · see citing works

Microcirculation in obesity: an unexplored domain

Wiernsperger, N. F., Nivoit, P., & Bouskela, E. (2007) · Anais da Academia Brasileira de Ciências · doi:10.1590/s0001-37652007000400005 · Cited by 11 · see citing works

Associations of cardiorespiratory fitness, physical activity, and BMI with arterial health in middle‐aged men and women

Haapala, E. A., Lee, E., & Laukkanen, J. A. (2020) · Physiological Reports · doi:10.14814/phy2.14438 · Cited by 12 · see citing works

Attenuation of Angiotensin II-Induced Hypertension and Cardiac Hypertrophy in Transgenic Mice Overexpressing a Type 1 Receptor Mutant

Ahmad, S., Cesana, F., Lamperti, E. D., Gavras, H. P., & Yu, J. (2009) · American Journal of Hypertension · doi:10.1038/ajh.2009.181 · Cited by 12 · see citing works

Serum nitric oxide metabolites are associated with the risk of hypertriglyceridemic-waist phenotype in women: Tehran Lipid and Glucose Study

Bahadoran, Z., Mirmiran, P., Ghasemi, A., & Azizi, F. (2015) · Nitric Oxide · doi:10.1016/j.niox.2015.08.002 · Cited by 11 · see citing works

The Effect of α-Lipoic Acid on Oxidative Stress in Adipose Tissue of Rats with Obesity-Induced Insulin Resistance

Dajnowicz-Brzezik, P., Żebrowska, E., Maciejczyk, M., Zalewska, A., & Chabowski, A. (2022) · Cellular Physiology and Biochemistry · doi:10.33594/000000528 · Cited by 10 · see citing works

The relationship between serum total sialic acid levels and adenosine deaminase activity in obesity

Kurtul, N., Akarsu, E., & Aktaran, Ş. (2006) · Saudi Medical Journal · doi:10.15537/1658-3175.3305 · Cited by 10 · see citing works

Combination of Gold Nanoparticles with Carnitine Attenuates Brain Damage in an Obesity Animal Model

da Silva, L. E., Abel, J. S., Tartari, G., da Silva, M. R., de Oliveira, M. P., Vedova, L. M. D., Mendes, T. F., Mendes, R. L., Soares, H. J., Vernke, C. N., et al. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-03984-1 · Cited by 9 · see citing works

Effect of plasma NOx values on cardiac function in obese hypertensive and normotensive pediatric patients

Akçaboy, M., Kula, S., Göktaş, T., Nazlıel, B., Terlemez, S., Çelik, N., Çelik, B., & Buyan, N. (2015) · Pediatric Nephrology · doi:10.1007/s00467-015-3223-2 · Cited by 8 · see citing works

Arterial insulin resistance in Yucatan micropigs with diet-induced obesity and metabolic syndrome

Wang, C. C. L., Lu, L., Leitner, J. W., Sarraf, M., Gianani, R., Draznin, B., Greyson, C. R., Reusch, J. E. B., & Schwartz, G. G. (2013) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2013.02.009 · Cited by 8 · see citing works

Signaling pathways associated with structural changes in varicose veins: a case–control study

Modaghegh, M. H. S., Saberianpour, S., Amoueian, S., & Kamyar, M. M. (2021) · Phlebology The Journal of Venous Disease · doi:10.1177/02683555211019537 · Cited by 7 · see citing works

Impact of Vitamin D Supplementation on Inflammatory Markers’ Levels in Obese Patients

Wiciński, M., Ozorowski, M., Wódkiewicz, E., Otto, S. W., Kubiak, K., & Malinowski, B. (2021) · Current Issues in Molecular Biology · doi:10.3390/cimb43030114 · Cited by 7 · see citing works

Actions of Esomeprazole on the Maternal Vasculature in Lean and Obese Pregnant Mice with Impaired Nitric Oxide Synthesis: A Model of Preeclampsia

de Alwis, N., Binder, N. K., Mangwiro, Y. T. M., Beard, S., Pritchard, N., Kadife, E., Fato, B. R., Keenan, E., Brownfoot, F., Kaitu’u‐Lino, T. J., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158185 · Cited by 7 · see citing works

A novel approach to the assessment of vascular endothelial function

Sathasivam, S., Phababpha, S., Sengmeuan, P., Detchaporn, P., Siddiqui, Z., Kukongviriyapan, U., & Greenwald, S. E. (2011) · Journal of Physics Conference Series · doi:10.1088/1742-6596/307/1/012014 · Cited by 7 · see citing works

Relation of Body's Lean Mass, Fat Mass, and Body Mass Index With Submaximal Systolic Blood Pressure in Young Adult Men

Prasad, V. K., Drenowatz, C. J., Hand, G. A., Lavie, C. J., Sui, X., DeMello, M. M., & Blair, S. N. (2015) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2015.10.060 · Cited by 7 · see citing works

Degree of obesity influences the relationship of PAI-1 with body fat distribution and metabolic variables in African women

Barnard, S. A., Pieters, M., Nienaber‐Rousseau, C., & Kruger, H. S. (2016) · Thrombosis Research · doi:10.1016/j.thromres.2016.09.003 · Cited by 7 · see citing works

Mecanismos de hipertensión en obesidad

de Fez, C. M. L., Gaztelu, M. T., Rubio, T., & Castaño, A. (2004) · Anales del Sistema Sanitario de Navarra · doi:10.4321/s1137-66272004000300006 · Cited by 7 · see citing works

Circulating nitric oxide metabolites and the risk of cardiometabolic outcomes: a prospective population-based study

Mirmiran, P., Bahadoran, Z., Tahmasebinejad, Z., Azizi, F., & Ghasemi, A. (2019) · Biomarkers · doi:10.1080/1354750x.2019.1567816 · Cited by 6 · see citing works

Postsynaptic cutaneous vasodilation and sweating: influence of adiposity and hydration status

Tucker, M. A., Caldwell, A. R., Butts, C. L., Robinson, F. B., Kavouras, S. A., McDermott, B. P., Washington, T. A., Turner, R. C., & Ganio, M. S. (2018) · European Journal of Applied Physiology · doi:10.1007/s00421-018-3902-3 · Cited by 6 · see citing works

Leptin and Insulin Action in Severely Obese Women

Papadia, F. S., Marinari, G. M., Camerini, G. B., Civalleri, D., Scopinaro, N., & Adami, G. (2003) · Obesity Surgery · doi:10.1381/096089203764467135 · Cited by 6 · see citing works

Metabolic syndrome

Lien, L. F., & Guyton, J. R. (2008) · Dermatologic Therapy · doi:10.1111/j.1529-8019.2008.00218.x · Cited by 6 · see citing works

A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension

Sasaki, S., Higashi, Y., Nakagawa, K., Kimura, M., Noma, K., Sasaki, S., Hara, K., Matsuura, H., Goto, C., Oshima, T., et al. (2002) · American Journal of Hypertension · doi:10.1016/s0895-7061(01)02322-6 · Cited by 136 · see citing works

Autonomic Blockade Reverses Endothelial Dysfunction in Obesity-Associated Hypertension

Gamboa, A. C., Figueroa, R., Paranjape, S. Y., Farley, G., Diedrich, A., & Biaggioni, I. (2016) · Hypertension · doi:10.1161/hypertensionaha.116.07681 · Cited by 45 · see citing works

Obesity-induced impairment of endothelium-dependent vasodilation in Tunisian women

Miâdi-Messaoud, H., Chouchane, A., Abderrazek, E., Debbabi, H., Zaouali, M., Tabka, Z., & Jebria, A. B. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.231 · Cited by 17 · see citing works

Enhanced Vascular Activity of Endogenous Endothelin-1 in Obese Hypertensive Patients

Cardillo, C., Campia, U., Iantorno, M., & Panza, J. A. (2003) · Hypertension · doi:10.1161/01.hyp.0000103868.45064.81 · Cited by 162 · see citing works

Ендотелійзалежна та ендотелійнезалежна вазодилятація у хворих на артеріальну гіпертензію з ожирінням

Руденко, Т. (2014)