The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
Voltage-Gated Ion Channels and Electrical Excitability
Open accessAbstract
Our ability to do gymnastics, to perceive a colorful world, and to process language relies on rapid communication among neurons. Such signaling, the fastest in our bodies, involves electrical messages produced as ion channels in cell membranes open and close. Various ion channels mediate sensory transduction, electrical “computations,” propagation over long distances, and synaptic transmission. Here, we focus on voltage-gated ion channels, the family of channels that includes the familiar Na+, K+, and Ca2+ channels of nerve and muscle excitability. In the computer metaphor of the brain, the voltage-gated ion channels are like the transistors of logical circuits, detecting, amplifying, and reshaping electrical messages. Our basic understanding of these proteins maintains the framework and rigor established 50 years ago by Hodgkin and Huxley 1952, enriched by much new molecular information and by insights gained from patch-clamp methods.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hodgkin, A. L., & Huxley, A. F. (1952) · The Journal of Physiology · doi:10.1113/jphysiol.1952.sp004764 · Cited by 23,191
Hamill, O. P., Marty, A., Neher, E., Sakmann, B., & Sigworth, F. J. (1981) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/bf00656997 · Cited by 18,436
The effect of sodium ions on the electrical activity of the giant axon of the squid
Hodgkin, A. L., & Katz, B. (1949) · The Journal of Physiology · doi:10.1113/jphysiol.1949.sp004310 · Cited by 3,520
Ionic Blockage of Sodium Channels in Nerve
Woodhull, A. M. (1973) · The Journal of General Physiology · doi:10.1085/jgp.61.6.687 · Cited by 1,569
Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation
Hoshi, T., Zagotta, W. N., & Aldrich, R. W. (1990) · Science · doi:10.1126/science.2122519 · Cited by 1,538
Inactivation of the sodium channel. I. Sodium current experiments.
Bezanilla, F., & Armstrong, C. M. (1977) · The Journal of general physiology · doi:10.1085/jgp.70.5.549 · Cited by 1,500
Self-citationStructural parts involved in activation and inactivation of the sodium channel
Stühmer, W., Conti, F., Suzuki, H., Wang, X., Noda, M., Yahagi, N., Kubo, H., & Numa, S. (1989) · Nature · doi:10.1038/339597a0 · Cited by 1,215
SCHNEIDER, M. F., & CHANDLER, W. K. (1973) · Nature · doi:10.1038/242244a0 · Cited by 992
Inactivation of the sodium channel. II. Gating current experiments.
Armstrong, C. M., & Bezanilla, F. (1977) · The Journal of general physiology · doi:10.1085/jgp.70.5.567 · Cited by 959
Self-citationInteraction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons
Armstrong, C. M. (1971) · The Journal of General Physiology · doi:10.1085/jgp.58.4.413 · Cited by 929
Self-citation
Cited by
Hans, M., Luvisetto, S., Williams, M. E., Spagnolo, M., Urrutia, A., Tottene, A., Brust, P. F., Johnson, E. C., Harpold, M. M., Stauderman, K. A., et al. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-05-01610.1999 · Cited by 268
Effects of membrane lipids on ion channel structure and function
Tillman, T. S., & Cascio, M. (2003) · Cell Biochemistry and Biophysics · doi:10.1385/cbb:38:2:161 · Cited by 265
Rau, A. R., Chappell, A. M., Butler, T. R., Ariwodola, O. J., & Weiner, J. L. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0384-15.2015 · Cited by 136
Metadata
- Authors
- Armstrong, C. M., & Hille, B.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 1998-03
- Volume
- 20
- Issue
- 3
- Pages
- 371-380
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2048268501
- Cited by
- 403
- References
- 61
- FWCI
- 7.99
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Voltage-Gated Ion Channels and Electrical Excitability. https://app.cochat.ai/papers/10.1016/s0896-6273(00)80981-2
- The paper
- Armstrong, C. M., & Hille, B. (1998). Voltage-Gated Ion Channels and Electrical Excitability. Neuron. https://doi.org/10.1016/s0896-6273(00)80981-2
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
