Knockout of ERK1 MAP Kinase Enhances Synaptic Plasticity in the Striatum and Facilitates Striatal-Mediated Learning and Memory

Emotion circuits in the brain

LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444

Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*

Pearson, G. W., Robinson, F. L., Gibson, T. B., Xu, B.-E., Karandikar, M. S., Berman, K. S., & Cobb, M. H. (2001) · Endocrine Reviews · doi:10.1210/edrv.22.2.0428 · Cited by 4,111

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

Favata, M. F., Horiuchi, K. Y., Manos, E. J., Daulerio, A. J., Stradley, D. A., Feeser, W. S., Dyk, D. E. V., Pitts, W. J., Earl, R. A., Hobbs, F. W., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.29.18623 · Cited by 3,016

Synaptic Plasticity and Memory: An Evaluation of the Hypothesis

Martin, S. J., Grimwood, P. D., & Morris, R. G. M. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.649 · Cited by 2,794

Molecular basis of long-term plasticity underlying addiction

Nestler, E. J. (2001) · Nature reviews. Neuroscience · doi:10.1038/35053570 · Cited by 1,893

Addiction and the brain: The neurobiology of compulsion and its persistence

Hyman, S. E., & Malenka, R. C. (2001) · Nature reviews. Neuroscience · doi:10.1038/35094560 · Cited by 1,337

Addiction, Dopamine, and the Molecular Mechanisms of Memory

Berke, J. D., & Hyman, S. E. (2000) · Neuron · doi:10.1016/s0896-6273(00)81056-9 · Cited by 1,184

Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens

Nicola, S. M., Surmeier, D. J., & Malenka, R. C. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.185 · Cited by 931

A Requirement for the Mitogen-activated Protein Kinase Cascade in Hippocampal Long Term Potentiation

English, J. D., & Sweatt, J. D. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.31.19103 · Cited by 860

Understanding Ras: ‘it ain’t over ’til it’s over’

Shields, J. M., Pruitt, K., McFall, A. J., Maddox, A. S., & Der, C. J. (2000) · Trends in Cell Biology · doi:10.1016/s0962-8924(00)01740-2 · Cited by 784

Molecular mechanisms of memory acquisition, consolidation and retrieval

Abel, T. G., & Lattal, K. M. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00194-x · Cited by 709

CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription

Foulkes, N. S., Borrelli, E., & Sassone‐Corsi, P. (1991) · Cell · doi:10.1016/0092-8674(91)90503-q · Cited by 656

Defective Thymocyte Maturation in p44 MAP Kinase (Erk 1) Knockout Mice

Pagès, G., Guérin, S., Grall, D., Bonino, F., Smith, A., Anjuere, F., Auberger, P., & Pouysségur, J. (1999) · Science · doi:10.1126/science.286.5443.1374 · Cited by 654

Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

Kelz, M. B., Chen, J., Carlezon, W. A., Whisler, K., Gilden, L., Beckmann, A. M., Steffen, C., Zhang, Y.-J., Marotti, L., Self, D. W., et al. (1999) · Nature · doi:10.1038/45790 · Cited by 641

Molecular Psychology: Roles for the ERK MAP Kinase Cascade in Memory

Adams, J. P., & Sweatt, J. D. (2002) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.42.082701.145401 · Cited by 598

The involvement of nucleus accumbens dopamine in appetitive and aversive motivation

Salamone, J. D. (1994) · Behavioural Brain Research · doi:10.1016/0166-4328(94)90153-8 · Cited by 584

Activation of p42 Mitogen-activated Protein Kinase in Hippocampal Long Term Potentiation

English, J. D., & Sweatt, J. D. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.40.24329 · Cited by 579

Building action repertoires: memory and learning functions of the basal ganglia

Graybiel, A. M. (1995) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(95)80100-6 · Cited by 572

Involvement of the Extracellular Signal-Regulated Kinase Cascade for Cocaine-Rewarding Properties

Valjent, E., Corvol, J., Pagès, C., Besson, M., Maldonado, R. J., & Caboche, J. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-23-08701.2000 · Cited by 571

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

Xu, M., Moratalla, R., Gold, L. H., Hiroi, N., Koob, G. F., Graybiel, A. M., & Tonegawa, S. (1994) · Cell · doi:10.1016/0092-8674(94)90557-6 · Cited by 481

A role for the Ras signalling pathway in synaptic transmission and long-term memory

Brambilla, R., Gnesutta, N., Minichiello, L., White, G., Roylance, A. J., Herron, C. E., Ramsey, M., Wolfer, D. P., Cestari, V., Rossi‐Arnaud, C., et al. (1997) · Nature · doi:10.1038/36849 · Cited by 474

Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

Maldonado, R. J., Saiardi, A., Valverde, O., Samad, T. A., Roques, B. P., & Borrelli, E. (1997) · Nature · doi:10.1038/41567 · Cited by 436

Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

Xu, M., Hu, X., Cooper, D., Moratalla, R., Graybiel, A. M., White, F. J., & Tonegawa, S. (1994) · Cell · doi:10.1016/0092-8674(94)90026-4 · Cited by 333

ERK Plays a Regulatory Role in Induction of LTP by Theta Frequency Stimulation and Its Modulation by β-Adrenergic Receptors

Winder, D. G., Martin, K. C., Muzzio, I. A., Rohrer, D. K., Chruscinski, A. J., Kobilka, B. K., & Kandel, E. R. (1999) · Neuron · doi:10.1016/s0896-6273(00)81124-1 · Cited by 326

Sequential Role of Hippocampus and Amygdala, Entorhinal Cortex and Parietal Cortex in Formation and Retrieval of Memory for Inhibitory Avoidance in Rats

Izquierdo, I., Quillfeldt, J. A., Zanatta, M. S., Quevedo, J., Schaeffer, E. L., Schmitz, P. K., & Medina, J. H. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01427.x · Cited by 316

Increased anxiety and synaptic plasticity in estrogen receptor β-deficient mice

Krężel, W., Dupont, S., Krust, A., Chambon, P., & Chapman, P. (2001) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.221451898 · Cited by 283

Genetic approaches to memory storage

Mayford, M. R. (1999) · Trends in Genetics · doi:10.1016/s0168-9525(99)01846-6 · Cited by 257

Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice

Martín, M., Ledent, C. A., Parmentier, M., Maldonado, R. J., & Valverde, O. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00287.x · Cited by 237

Mice Lacking the ERK1 Isoform of MAP Kinase Are Unimpaired in Emotional LearningPreprint

Selcher, J. C., Nekrasova, T., Paylor, R. E., Landreth, G. E., & Sweatt, J. D. (2001) · Learning & Memory · doi:10.1101/lm.37001 · Cited by 212

Toward a Molecular Explanation for Long-Term PotentiationPreprint

Sweatt, J. D. (1999) · Learning & Memory · doi:10.1101/lm.6.5.399 · Cited by 193

Is the Ras-MAPK signalling pathway necessary for long-term memory formation?

Orban, P. C., Chapman, P. F., & Brambilla, R. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01306-x · Cited by 189

Ras-related and MAPK signalling in neuronal plasticity and memory formation

Mazzucchelli, C., & Brambilla, R. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000722 · Cited by 165

Behavioral study after local injection of 6-hydroxydopamine into the nucleus accumbens in the rat

Taghzouti, K., Simon, H., Louilot, A., Herman, J., & Moal, M. L. (1985) · Brain Research · doi:10.1016/0006-8993(85)91184-9 · Cited by 107

Iontophoretic injection of fluoro-gold and other fluorescent tracers.

Schmued, L. C., & Heimer, L. (1990) · Journal of Histochemistry & Cytochemistry · doi:10.1177/38.5.2332627 · Cited by 80

Novel mutant Semliki Forest virus vectors: gene expression and localization studies in neuronal cells

Lundstrom, K. H., Rotmann, D., Hermann, D., Schneider, E. M., & Ehrengruber, M. U. (2000) · Histochemistry and Cell Biology · doi:10.1007/s004180000223 · Cited by 75

Addiction and the brain

Powledge, T. M. (1999) · BioScience · doi:10.2307/1313471 · Cited by 70

The central amygdala is involved in conditioning but not in retention of active and passive shock avoidance in male rats

Roozendaal, B., Koolhaas, J. M., & Bohus, B. (1993) · Behavioral and Neural Biology · doi:10.1016/0163-1047(93)90873-g · Cited by 60

Contrasting Calcium Dependencies of SAPK and ERK Activations by Glutamate in Cultured Striatal Neurons

Schwarzschild, M. A., Cole, R. L., Meyers, M. A., & Hyman, S. E. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0722248.x · Cited by 46

Effect of brain lesions on rat shuttle behavior in four different tests

Schütz, R. A., & Izquierdo, I. (1979) · Physiology & Behavior · doi:10.1016/0031-9384(79)90128-8 · Cited by 29

Basal ganglia, Parkinson's disease and levedopa therapy

Obeso, J. A., Olanow, C. W., & Nutt, J. G. (2000) · Trends in Neurosciences · doi:10.1016/s1471-1931(00)00060-4 · Cited by 18

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

McCubrey, J. A., Steelman, L. S., Chappell, W. H., Abrams, S. L., Wong, E. W. T., Chang, F., Lehmann, B. D., Terrian, D. M., Milella, M., Tafuri, A., et al. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.10.001 · Cited by 2,349

Mitogen-activated protein kinases in synaptic plasticity and memory

Sweatt, J. D. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.04.001 · Cited by 1,013

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

Mebratu, Y. A., & Tesfaigzi, Y. (2009) · Cell Cycle · doi:10.4161/cc.8.8.8147 · Cited by 989

The MEK/ERK cascade: From signaling specificity to diverse functions

Shaul, Y. D., & Seger, R. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.10.005 · Cited by 969

Translational Control by MAPK Signaling in Long-Term Synaptic Plasticity and Memory

Kelleher, R. J., Govindarajan, A., Jung, H.-Y., Kang, H., & Tonegawa, S. (2004) · Cell · doi:10.1016/s0092-8674(04)00115-1 · Cited by 845

Contributions of ERK signaling in the striatum to instrumental learning and performance

Shiflett, M. W., & Balleine, B. W. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.12.010 · Cited by 94

Extracellular Signal-Regulated Kinase, Synaptic Plasticity, and Memory

Thiels, E., & Klann, E. (2001) · Reviews in the Neurosciences · doi:10.1515/revneuro.2001.12.4.327 · Cited by 98

Ras-grf1 regulates striatum-dependent behavioural plasticity, long term synaptic signalling and responses to drugs of abuse

FASANO, S. G., Orban, P., Valjent, E., Vara, H., Putignano, E., Centonze, D., A., P., Saulle, E., Maldonado, R. J., Chapman, P., et al. (2004) · Institutional Research Information System University of Turin (University of Turin)

Molecular Psychology: Roles for the ERK MAP Kinase Cascade in Memory

Adams, J. P., & Sweatt, J. D. (2002) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.42.082701.145401 · Cited by 598

Contributions of extracellular-signal regulated kinase 1/2 activity to the memory trace

Ramos, S. O., Feld, M., & Fustiñana, M. S. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.988790 · Cited by 43