The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone
Open accessAbstract
Women mount more vigorous antibody- and cell-mediated immune responses following either infection or vaccination than men. The incidence of most autoimmune diseases is also higher in women than in men; however, during pregnancy many autoimmune diseases go into remission, only to flare again in the early post-partum period. Successful pregnancy requires that the female immune system tolerate the presence of a semi-allogeneic graft for 9 months. Oral contraceptive use can increase susceptibility to certain genital tract infections and sexually transmitted diseases in women. Moreover, treatment of mice and rats with female sex hormones is required to establish animal models of genital tract Chlamydia, Neisseria and Mycoplasma infection. This review describes what is currently known about the effects of the female sex hormones oestradiol and progesterone on innate and adaptive immune responses in order to provide a framework for understanding these sex differences. Data from both human and animal studies will be reviewed.
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Cites
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Toll-like receptors: critical proteins linking innate and acquired immunity
Akira, S., Takeda, K., & Kaisho, T. (2001) · Nature Immunology · doi:10.1038/90609 · Cited by 4,777
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Decoding the Patterns of Self and Nonself by the Innate Immune System
Medzhitov, R., & Janeway, C. A. (2002) · Science · doi:10.1126/science.1068883 · Cited by 2,154
Natural killer cells and pregnancy
Moffett-King, A. (2002) · Nature Reviews Immunology · doi:10.1038/nri886 · Cited by 1,235
Steroid receptor expression in uterine natural killer cells
Henderson, T. A., Saunders, P. T. K., Moffett-King, A., Groome, N. P., & Critchley, H. O. D. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021174 · Cited by 283
Zhao, X. J. (2001) · Thorax · doi:10.1136/thorax.56.3.205 · Cited by 120 · cited 1×
“The presence of progesterone receptors on T lymphocytes remains controversial [75,76].”
Background
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Metadata
- Authors
- Beagley, K. W., & Gockel, C. M.
- Venue
- FEMS Immunology & Medical Microbiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-08
- Volume
- 38
- Issue
- 1
- Pages
- 13-22
- ISSN
- 0928-8244 (ISSN-L)
- 1574-695X
- OpenAlex
- W1990042770
- Cited by
- 484
- References
- 7
- FWCI
- 10.05
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Beagley, K. W., & Gockel, C. M. (2003). Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone. FEMS Immunology & Medical Microbiology. https://doi.org/10.1016/s0928-8244(03)00202-5
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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