CoChat
Sign Up
Cited by 103

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Functional dissection of BCR signaling pathways

Kurosaki, Tomohiro·2000·Current Opinion in Immunology
DOI 10.1016/s0952-7915(00)00087-x
Open this paper in CoChat — free account

Abstract

Signal transduction by the BCR is critical for progression through developmental checkpoints as well as for immune responses. Recent results obtained in mice deficient either in an adaptor molecule, BLNK (alternatively named SLP-65 or BASH), or in phosphatidylinositol 3-kinase have revealed similar - though not identical - phenotypes to those of Btk(-/-) mice, suggesting a functional link between BLNK, Btk and phosphatidylinositol 3-kinase.

Overview

Integrity signals

Registry

Crossref · 10.1016/s0952-7915(00)00087-x

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 53

  1. Cheng, 1995, Syk tyrosine kinase required for mouse viability and B-cell development, Nature, 378, 303, 10.1038/378303a0 · DOI · Paper page
  2. Turner, 1995, Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk, Nature, 378, 298, 10.1038/378298a0 · DOI · Paper page
  3. Karasuyama, 1996, Surrogate light chain in B cell development, Adv Immunol, 63, 1, 10.1016/S0065-2776(08)60853-6 · DOI
  4. Papavasiliou, 1995, The cytoplasmic domains of immunoglobulin (Ig)α and Igβ can independently induce the precursor B cell transition and allelic exclusion, J Exp Med, 182, 1389, 10.1084/jem.182.5.1389 · DOI
  5. Papavasiliou, 1995, The role of Igβ in precursor B cell transition and allelic excludion, Science, 268, 408, 10.1126/science.7716544 · DOI
  6. Teh, 1997, The immunoglobulin (Ig)α and Igβ cytoplasmic domains are independently sufficient to signal B cell maturation and activation in transgenic mice, J Exp Med, 185, 1753, 10.1084/jem.185.10.1753 · DOI
  7. Sanchez, 1993, Signal tranduction by immunoglobilin is mediated through Igα and Igβ, J Exp Med, 178, 1049, 10.1084/jem.178.3.1049 · DOI
  8. Gong, 1996, Regulation of an early developmental checkpoint in the B cell pathway by Igβ, Science, 272, 411, 10.1126/science.272.5260.411 · DOI · Paper page
  9. Caldwell, 1998, Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals, Immunity, 9, 405, 10.1016/S1074-7613(00)80623-8 · DOI
  10. Nagata, 1997, The Igα/Igβ heterodimer on μ-negative pro B cells is competent for transducing signals to induce early B cell differentiation, Immunity, 7, 559, 10.1016/S1074-7613(00)80377-5 · DOI
  11. Torres, 1996, Aberrant B cell development and immune response in mice with a compromised BCR complex, Science, 272, 1804, 10.1126/science.272.5269.1804 · DOI · Paper page
  12. Torres, 1999, A negative regulatory role for Ig-α during B cell development, Immunity, 11, 527, 10.1016/S1074-7613(00)80128-4 · DOI
  13. Kurosaki, 1999, Genetic analysis of B cell antigen receptor signalling, Annu Rev Immunol, 17, 555, 10.1146/annurev.immunol.17.1.555 · DOI
  14. Campbell, 1999, Signal transduction from the B cell antigen-receptor, Curr Opin Immunol, 11, 256, 10.1016/S0952-7915(99)80042-9 · DOI
  15. Fu, 1997, Identification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cγ, Grb2 and Vav after B cell antigen receptor activation, J Biol Chem, 272, 27362, 10.1074/jbc.272.43.27362 · DOI
  16. Fu, 1998, BLNK: a central linker protein in B cell activation, Immunity, 9, 93, 10.1016/S1074-7613(00)80591-9 · DOI
  17. Goitsuka, 1998, BASH, a novel signaling molecule preferentially expressed in B cells of the bursa of fabricius, J Immunol, 161, 5804, 10.4049/jimmunol.161.11.5804 · DOI
  18. Wienands, 1998, SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation, J Exp Med, 188, 791, 10.1084/jem.188.4.791 · DOI · Paper page
  19. Jumaa, 1999, Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65, Immunity, 11, 547, 10.1016/S1074-7613(00)80130-2 · DOI
  20. Pappu, 1999, Requirement for B cell linker protein (BLNK) in B cell development, Science, 286, 1949, 10.1126/science.286.5446.1949 · DOI
  21. Minegishi, 1999, An essential role for BLNK in human B cell development, Science, 286, 1954, 10.1126/science.286.5446.1954 · DOI
  22. Hayashi, 2000, The B cell-restricted BASH is required for normal development and antigen receptor-mediated activation of B cells, Proc Natl Acad Sci USA, 10.1073/pnas.040575697 · DOI
  23. Zhang, 1998, Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk, EMBO J, 17, 7304, 10.1093/emboj/17.24.7304 · DOI
  24. Shaw, 1999, Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes, J Exp Med, 189, 123, 10.1084/jem.189.1.123 · DOI · Paper page
  25. Iritani, 1999, Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors, Immunity, 10, 713, 10.1016/S1074-7613(00)80070-9 · DOI
  26. Carsetti, 2000, The development of B cells in the bone marrow is controlled by the balance between cell-autonomous mechanisms and signals from the microenvironment, J Exp Med, 191, 5, 10.1084/jem.191.1.5 · DOI
  27. Lam, 1997, In vivo ablation of surface immunogloubulin on mature B cells by inducible gene targeting results in rapid cell death, Cell, 90, 1073, 10.1016/S0092-8674(00)80373-6 · DOI
  28. Kerner, 1995, Impaired expansion of mouse B cell progenitors lacking Btk, Immunity, 3, 301, 10.1016/1074-7613(95)90115-9 · DOI
  29. Khan, 1995, Defective B cell development and function in Btk-deficient mice, Immunity, 3, 283, 10.1016/1074-7613(95)90114-0 · DOI
  30. Hashimoto, 1999, Identification of the SH2 domain binding protein of Bruton’s tyrosine kinase as BLNK — functional significance of Btk-SH2 domain in B cell antigen receptor-coupled calcium signalling, Blood, 94, 2357, 10.1182/blood.V94.7.2357.419k40_2357_2364 · DOI
  31. Su, 1999, Interaction of SLP adaptors with the SH2 domain of Tec family kinases, Eur J Immunol, 29, 3702, 10.1002/(SICI)1521-4141(199911)29:11<3702::AID-IMMU3702>3.0.CO;2-R · DOI
  32. Leitges, 1996, Immunodeficiency in protein kinase Cβ-deficient mice, Science, 273, 788, 10.1126/science.273.5276.788 · DOI
  33. Suzuki, 1999, Xid-like immunodeficiency in mice with disruption of the p85α subunit of phosphoinositide 3-kinase, Science, 283, 390, 10.1126/science.283.5400.390 · DOI
  34. Fruman, 1999, Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α, Science, 283, 393, 10.1126/science.283.5400.393 · DOI · Paper page
  35. Salim, 1996, Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton’s tyrosine kinase, EMBO J, 15, 6241, 10.1002/j.1460-2075.1996.tb01014.x · DOI
  36. Li, 1997, Phosphatidylinositol 3-kinase-γ activates Bruton’s tyrosine kinase in concert with Src family kinases, Proc Natl Acad Sci USA, 94, 13820, 10.1073/pnas.94.25.13820 · DOI
  37. August, 1997, Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the pleckstrin homology domain of inducible T cell kinase, Proc Natl Acad Sci USA, 94, 11227, 10.1073/pnas.94.21.11227 · DOI
  38. Gay, 1993, Receptor editing: an approach by autoreactive B cells to escape tolerance, J Exp Med, 177, 999, 10.1084/jem.177.4.999 · DOI
  39. Goodnow, 1996, Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires, Proc Natl Acad Sci USA, 93, 2264, 10.1073/pnas.93.6.2264 · DOI
  40. Klinman, 1996, The “clonal selection hypothesis” and current concepts of B cell tolerance, Immunity, 5, 189, 10.1016/S1074-7613(00)80314-3 · DOI
  41. Monroe, 1996, Tolerance sensitivity of immature-stage B cells: can developmentally regulated B cell antigen receptor (BCR) signal transduction play a role?, J Immunol, 156, 2657, 10.4049/jimmunol.156.8.2657 · DOI
  42. Nossal, 1994, Negative selection of lymphocytes, Cell, 76, 229, 10.1016/0092-8674(94)90331-X · DOI
  43. Radic, 1996, Receptor editing, immune diversification, and self-tolerance, Immunity, 5, 505, 10.1016/S1074-7613(00)80266-6 · DOI
  44. Tiegs, 1993, Receptor editing in self-reactive bone marrow B cells, J Exp Med, 177, 1009, 10.1084/jem.177.4.1009 · DOI
  45. Goodnow, 1992, Transgenic mice and analysis of B-cell tolerance, Annu Rev Immunol, 10, 489, 10.1146/annurev.iy.10.040192.002421 · DOI
  46. Kraus, 1999, Ig-α cytoplasmic truncation renders immature B cells more sensitive to antigen contact, Immunity, 11, 537, 10.1016/S1074-7613(00)80129-6 · DOI
  47. Cyster, 1995, Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection, Immunity, 2, 13, 10.1016/1074-7613(95)90075-6 · DOI
  48. Cornall, 1998, Polygenic autoimmune traits: Lyn, CD22 and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection, Immunity, 8, 497, 10.1016/S1074-7613(00)80554-3 · DOI
  49. Melamed, 1998, Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection, Cell, 92, 173, 10.1016/S0092-8674(00)80912-5 · DOI
  50. Sandel, 1999, Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter, Immunity, 10, 289, 10.1016/S1074-7613(00)80029-1 · DOI
  51. Lang, 1997, Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells, J Exp Med, 186, 1513, 10.1084/jem.186.9.1513 · DOI
  52. Fang, 1998, Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing, Immunity, 9, 35, 10.1016/S1074-7613(00)80586-5 · DOI
  53. Benschop, 1999, Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells, J Exp Med, 190, 749, 10.1084/jem.190.6.749 · DOI

Cited by

Sorted by citations

Metadata

Authors
Kurosaki, T.
Venue
Current Opinion in Immunology
Publisher
Elsevier BV
Published
2000-06
Volume
12
Issue
3
Pages
276-281
ISSN
0952-7915
DOI
10.1016/s0952-7915(00)00087-x
Cited by
103
References
1
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review