The DOI matches its Crossref record; 65 of the 66 references it cites were found in a registry or an index.
Signaling mechanisms underlying dendrite formation
Abstract
During development, the nervous system is confronted with a problem of enormous complexity; to progress from a large number of 'disconnected' neurons to a network of neuronal circuitry that is able to dynamically process sensory information and generate an appropriate output. To form these circuits, growing axons must make synapses with targets, usually the dendrites of postsynaptic neurons. Although a significant amount is known about the signals that regulate and guide developing axons, we are only now starting to understand how environmental cues like growth factors and activity regulate the formation and maintenance of dendrites in the developing and mature nervous system.
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“Dendritic development is regulated by a combination of intrinsic programs and extrinsic factors78.”
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Metadata
- Authors
- Miller, F. D., & Kaplan, D. R.
- Affiliations
- Hospital for Sick Children (CA)
- Corresponding author
- Miller, Freda D
- Venue
- Current Opinion in Neurobiology
- Publisher
- Elsevier BV
- Published
- 2003-06
- Volume
- 13
- Issue
- 3
- Pages
- 391-398
- ISSN
- 0959-4388 (ISSN-L)
- OpenAlex
- W1984418778
- Cited by
- 160
- References
- 66
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 6 · 2016: 6 · 2015: 3 · 2014: 6 · 2013: 9 · 2012: 11
- FWCI
- 1.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Neurobiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Axon Guidance and Neuronal Signaling
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- dendrite formation, neural circuit formation, axon guidance, synaptogenesis, growth factors, neuronal activity, postsynaptic neurons, brain development
- MeSH terms
- Animals, Dendrites, Humans, Signal Transduction
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