The DOI matches its Crossref record; 49 of the 51 references it cites were found in a registry or an index.
Sociodemographic factors and quality of life as prognostic indicators in head and neck cancer
Abstract
Pre-treatment quality of life (QOL) has been found to be an independent prognostic factor for survival in cancer patients, in particular in patients with advanced cancer. Sociodemographic factors such as marital and socioeconomic status have also been recognised as prognostic factors. We studied the influence of QOL and mood (measured with the European Organization for Research and Treatment of Cancer Core Questionnaire (EORTC QLQ-C30) and the Head and Neck Cancer Questionnaire (EORTC QLQ-H&N35), and with the Center for Epidemiologic Studies-Depression Scale (CES-D)) as measured before treatment, the use of cigarettes and alcohol and sociodemographic factors (age, gender, marital status, income and occupation) on recurrence and survival in 208 patients with head and neck cancer prior to treatment with surgery and/or radiotherapy, using Kaplan-Meier and Cox regression analyses. Cognitive functioning and, to a lesser degree, marital status were independent predictors of recurrence and survival, along with medical factors (stage and radicality). Patients with less than optimal cognitive functioning and unmarried patients had a relative risk (RR) of recurrence of 1.72 (95% confidence interval (95% CI) 1.01-2.93) and 1.85 (95% CI 1.06-3.33), respectively, and a RR of dying of 1.90 (95% CI 1.10-3.26) and 1.82 (95% CI 1.03-3.23), respectively. Performance status, physical functioning, mood and global QOL and smoking and drinking did not predict for recurrence and survival. The influence of cognitive functioning might be related to the use of alcohol. Marital status may influence prognosis through mechanisms of health behaviour and/or social support mechanisms.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Since poor QoL is associated with a higher risk of mortality in HNC patients [55–57], and psychological interventions targeting body image distress and pain have shown their effectiveness [58], focusing on these dimensions before HNC treatment might be crucial for improving patients’ overall QoL and survival rates.”
From Psychological variables associated with quality of life in patients with head and neck cancer: the role of body image distress (2022) · cites this paper as [55]
Citations
Cites
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., Filiberti, A., Flechtner, H., Fleishman, S. B., Haes, J. C. J. M. D., et al. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.5.365 · Cited by 16,005
Norussis, H. (1993) · Medical Entomology and Zoology · Cited by 2,704
Measuring the quality of life of cancer patients
Spitzer, W. O., Dobson, A. J., Hall, J. P., Chesterman, E., Levi, J. A., Shepherd, R., Battista, R. N., & Catchlove, B. R. (1981) · Journal of Chronic Diseases · doi:10.1016/0021-9681(81)90058-8 · Cited by 1,521
Evaluation of Chemotherapeutic Agents.
(1950) · Archives of Internal Medicine · doi:10.1001/archinte.1950.00230180176018 · Cited by 1,134
Evaluation of chemotherapeutic agents
A.R.L. (1950) · The American Journal of Medicine · doi:10.1016/0002-9343(50)90056-8 · Cited by 1,007
Evaluation of patients with advanced cancer using the karnofsky performance status
Yates, J. W., Chalmer, B. J., & McKegney, F. P. (1980) · Cancer · doi:10.1002/1097-0142(19800415)45:8 · Cited by 899
Bjordal, K., Hammerlid, E. B., Ahlner‐Elmqvist, M., de Graeff, A., Boysen, M., Evensen, J. F., Biörklund, A., de Leeuw, J. R. J., Fayers, P. M., Jannert, M., et al. (1999) · Journal of Clinical Oncology · doi:10.1200/jco.1999.17.3.1008 · Cited by 861
European Organization for Research and Treatment of Cancer
National Cancer Institute (2020) · Definitions · doi:10.32388/ykqg4k · Cited by 758
The Effect of Marital Status on Stage, Treatment, and Survival of Cancer Patients
Goodwin, J. S. (1987) · JAMA · doi:10.1001/jama.1987.03400210067027 · Cited by 542
Cited by
Sorted by citations
Chida, Y., & Steptoe, A. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31818105ba · Cited by 1,592
Depression as a predictor of disease progression and mortality in cancer patients: A Meta‐Analysis
Satin, J. R., Linden, W., & Phillips, M. J. (2009) · Cancer · doi:10.1002/cncr.24561 · Cited by 972
Montazeri, A. (2009) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-7-102 · Cited by 569
Associations of social networks with cancer mortality: a meta-analysis
Pinquart, M., & Duberstein, P. R. (2010) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2009.06.003 · Cited by 460
“[46] observed that marital status and social ctivity were univariate predictors of survival but were no onger significant in multivariate analysis that controlled for onfounding variables.”
BackgroundClinical Predictors of Quality of Life in Patients With Head and Neck Cancer
Terrell, J. E., Ronis, D. L., Fowler, K. E., Bradford, C. R., Chepeha, D. B., Prince, M. E. P., Teknos, T. N., Wolf, G. T., & Duffy, S. A. (2004) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.130.4.401 · Cited by 454
Health-Related Quality of Life in Oral Cancer: A Review
Chandu, A., Smith, A. C., & Rogers, S. N. (2006) · Journal of Oral and Maxillofacial Surgery · doi:10.1016/j.joms.2005.11.028 · Cited by 261
Colevas, A. D. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.05.3348 · Cited by 258
“Additional predictors of poor outcome or shortened survival that should be considered when making treatment decisions include the presence of hypercalcemia and comorbidities such as poor cognitive function; ongoing heavy tobacco, alcohol, or other carcinogen use; and the absence of a strong social support system.(12-1…”
BackgroundRogers, S. N., Ahad, S. A., & Murphy, A. P. (2007) · Oral Oncology · doi:10.1016/j.oraloncology.2007.02.006 · Cited by 252
Curran, D., Giralt, J., Harari, P. M., Ang, K. K., Cohen, R. B., Kies, M. S., Jassem, J., Baselga, J. M., Rowinsky, E. K., Amellal, N., et al. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.08.8005 · Cited by 247
Allison, P. J., Guichard, C., Fung, K., & Gilain, L. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.10.092 · Cited by 216
Race and Gender Differences in Willingness to Donate Blood and Cadaveric Organs
Boulware, L. E., Ratner, L. E., Cooper, L. A., Sosa, J. A., LaVeist, T. A., & Powe, N. R. (2002) · Medical Care · doi:10.1097/00005650-200202000-00003 · Cited by 204
“8 31–45 37 (32) 21 (46) 36 (33) 23 (33) 46–60 31 (27) 10 (22) 31 (28) 18 (26) 61 and older 12 (11) 7 (15) 17 (15) 9 (13) Education High school or less 56 (49) 22 (48) 31 (28) 13 (19) 0.”
Effect of smoking, alcohol, and depression on the quality of life of head and neck cancer patients
Duffy, S. A., Terrell, J. E., Valenstein, M. M., Ronis, D. L., Copeland, L. A., & Connors, M. (2002) · General Hospital Psychiatry · doi:10.1016/s0163-8343(02)00180-9 · Cited by 198
Quality of Life Scores Predict Survival Among Patients With Head and Neck Cancer
Karvonen-Gutierrez, C. A., Ronis, D. L., Fowler, K. E., Terrell, J. E., Gruber, S. B., & Duffy, S. A. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.12.9510 · Cited by 179
Spirituality, quality of life, psychological adjustment in terminal cancer patients in hospice
Bovero, A., Leombruni, P., Miniotti, M., Rocca, G., & Torta, R. (2015) · European Journal of Cancer Care · doi:10.1111/ecc.12360 · Cited by 181
Efficace, F., Biganzoli, L., Piccart, M. J., Coens, C., Steen, K. V., Čufer, T., Coleman, R. E., Calvert, H., Gamucci, T., Twelves, C., et al. (2004) · European Journal of Cancer · doi:10.1016/j.ejca.2004.01.014 · Cited by 162
Arnold, S. D., Forman, L. M., Brigidi, B. D., Carter, K. E., Schweitzer, H., Quinn, H. E., Guill, A. B., Herndon, J. E., & Raynor, R. H. (2008) · Neuro-Oncology · doi:10.1215/15228517-2007-057 · Cited by 160
Fang, F., Liu, Y., Tang, Y., Wang, C., & Ko, S. (2004) · Cancer · doi:10.1002/cncr.20010 · Cited by 156
“It contains five functional scales (physical, role, cognitive, emotional, and social), three symptom scales (fatigue, pain, and nausea/emesis), a global QoL scale, and six single items (dyspnea, insomnia, appetite loss, constipation, diarrhea, and financial difficulties).20,21 The EORTC QLQ-H&N35 is a specific module…”
MethodResultInfluentialDuffy, S. A., Ronis, D. L., McLean, S. A., Fowler, K. E., Gruber, S. B., Wolf, G. T., & Terrell, J. E. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.18.2188 · Cited by 153
Choi, S. H., Terrell, J. E., Fowler, K. E., McLean, S. A., Ghanem, T., Wolf, G. T., Bradford, C. R., Taylor, J. M. G., & Duffy, S. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149886 · Cited by 144
“[5, 8, 31–33] A relationship between marital status and survival and recurrence has also been reported among cancer patients.[17, 18, 31, 34, 35] Limitations on the studies of disparities among head and neck cancer patients include their retrospective nature,[8, 10, 17] inability to control for covariates,[14, 19, 23,…”
BackgroundMarital status and survival in cancer patients: A systematic review and meta‐analysis
Krajc, K., Miroševič, Š., Sajovic, J., Klemenc–Ketiš, Z., Spiegel, D., Drevenšek, G., & Drevenšek, M. (2022) · Cancer Medicine · doi:10.1002/cam4.5003 · Cited by 142
Eton, D. T., Fairclough, D. L., Cella, D. F., Yount, S., Bonomi, P., & Johnson, D. H. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.07.128 · Cited by 126
Quality of life is predictive of survival in patients with unresectable hepatocellular carcinoma
Yeo, W., Mo, F. K. F., Koh, J., Chan, A. T. �., Leung, T., Hui, P., Chan, S. L., Tang, A., Lee, J. J., Mok, T. S. K., et al. (2006) · Annals of Oncology · doi:10.1093/annonc/mdl065 · Cited by 122
“While this relationship has not been universally observed in the literature, such positive correlation has been reported in a number of cancer types [29–32], specifically, in the breast [33–35], lung [36–39], esophagus [40–42], head and neck [43], colon [44], malignant melanoma [45], multiple myeloma [46], ovarian [47…”
BackgroundMauer, M. E. L., Stupp, R., TAPHOORN, M. J. B., Coens, C., Osoba, D., Marosi, C., Wong, R. K. S., Witte, O. D., Cairncross, J. G., Efficace, F., et al. (2007) · British Journal of Cancer · doi:10.1038/sj.bjc.6603876 · Cited by 117
“…et al, 2006), oesophageal (Blazeby et al, 2001; Fang et al, 2004), advanced breast (Luoma et al, 2003; Efficace et al, 2004a), and head and neck (de Graeff et al, 2001) Received 2 April 2007; revised 11 June 2007; accepted 11 June 2007; published online 3 July 2007 *Correspondence: Dr M Mauer;…”
BackgroundEfficace, F., Therasse, P., Piccart, M. J., Coens, C., Steen, K. V., Wełnicka-Jaśkiewicz, M., Čufer, T., Dyczka, J., Lichinitser, M. R., Shepherd, L. E., et al. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.02.060 · Cited by 117
Quality of life in terminal care—with special reference to age, gender and marital status
Hagelin, C. L., Seiger, Å., & Fürst, C. J. (2005) · Supportive Care in Cancer · doi:10.1007/s00520-005-0886-4 · Cited by 114
“In another study of patients with newly diagnosed cancer, marital status was found to provide social support and to be a positive prognostic factor [15].”
BackgroundChanges in Quality of Life Over 1 Year in Patients With Head and Neck Cancer
Ronis, D. L., Duffy, S. A., Fowler, K. E., Khan, M. J., & Terrell, J. E. (2008) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archoto.2007.43 · Cited by 113
Jensen, K., Jensen, A. B., & Grau, C. (2006) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2006.02.005 · Cited by 112
“Other quality of life endpoints, like cognitive function and global quality of life have also been shown to be strong prognostic factors for survival [16,17].”
BackgroundA prospective study on malnutrition and quality of life in patients with head and neck cancer
van den Berg, M. G. A., Rasmussen‐Conrad, E. L., van Nispen, L., van Binsbergen, J. J., & Merkx, M. A. W. (2008) · Oral Oncology · doi:10.1016/j.oraloncology.2007.11.002 · Cited by 110
Singer, S., Arrarás, J. I., Chie, W., Fisher, S. E., Galalae, R., Hammerlid, E. B., Nicolatou‐Galitis, O., Schmalz, C., Leeuw, I. M. V., Gamper, E., et al. (2012) · Quality of Life Research · doi:10.1007/s11136-012-0325-1 · Cited by 106
Leeuw, I. M. V., Buffart, L. M., Heymans, M. W., Rietveld, D. H. F., Doornaert, P., de Bree, R., Buter, J., Aaronson, N. K., Slotman, B. J., Leemans, C. R., et al. (2014) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2014.01.002 · Cited by 102
“Similarly, 9 of 11 studies in HNSCC found HRQOL to be an independent predictor of survival [50–60].”
BackgroundMarital status, treatment, and survival in patients with glioblastoma multiforme
Chang, S. M., & Barker, F. G. (2005) · Cancer · doi:10.1002/cncr.21399 · Cited by 101
Emotional functioning of patients with neurofibromatosis tumor suppressor syndrome
Wang, D. L., Smith, K. B., Esparza, S., Leigh, F. A., Muzikansky, A., Park, E. R., & Plotkin, S. R. (2012) · Genetics in Medicine · doi:10.1038/gim.2012.85 · Cited by 100
Meyer, F., Fortin, A., Gélinas, M., Nabid, A., Brochet, F., Têtu, B., & Bairati, I. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.20.0295 · Cited by 97
Free‐Flap Head and Neck Reconstruction and Quality of Life: A 2‐Year Prospective Study
Bozec, A., Poissonnet, G., Chamorey, E., Casanova, C., Vallicioni, J., Demard, F., Mahdyoun, P., Peyrade, F., Follana, P., Bensadoun, R., et al. (2008) · The Laryngoscope · doi:10.1097/mlg.0b013e3181644abd · Cited by 96
Depression and Survival in Patients With Head and Neck Cancer
Barber, B. R., Dergousoff, J., Slater, L., Harris, J. R., O’Connell, D. A., El‐Hakim, H., Biron, V. L., Mitchell, N., & Seikaly, H. R. (2016) · JAMA Otolaryngology–Head & Neck Surgery · doi:10.1001/jamaoto.2015.3171 · Cited by 95
Efficace, F., Innominato, P. F., Bjarnason, G. A., Coens, C., Humblet, Y., Tumolo, S., Genet, D., Tampellini, M., Bottomley, A., Garufi, C., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.12.3117 · Cited by 94
Borggreven, P. A., Aaronson, N. K., Leeuw, I. M. V., Muller, M. J., Heiligers, M. L. C. H., de Bree, R., Langendijk, J. A., & Leemans, C. R. (2007) · Oral Oncology · doi:10.1016/j.oraloncology.2006.11.017 · Cited by 92
Fang, F., Tsai, W., Chiu, H., Kuo, W., & Hsiung, C. (2004) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2003.09.100 · Cited by 91
Burris, J. L., Studts, J. L., DeRosa, A. P., & Ostroff, J. S. (2015) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-15-0257 · Cited by 90
Prioritizing treatment outcomes: Head and neck cancer patients versus nonpatients
List, M. A., Smith, J. L., Stracks, J. S., Pauloski, B. R., Logemann, J. A., Lundy, D. S., Sullivan, P. A., GOODWIN, W. J., Kies, M. S., & Vokes, E. E. (2004) · Head & Neck · doi:10.1002/hed.10367 · Cited by 88
“25 Having normal amount of energy 57 (23) 26 (20) .”
BackgroundDeterioration in quality‐of‐life of late (10‐year) survivors of head and neck cancer
Mehanna, H. M., & Morton, R. P. (2006) · Clinical Otolaryngology · doi:10.1111/j.1749-4486.2006.01188.x · Cited by 86
Luoma, M., Hakamies‐Blomqvist, L., Sjöström, J., Pluzanska, A., Ottoson, S., Mouridsen, H. T., Bengtsson, N., Bergh, J. C. S., Malmström, P., Valvere, V., et al. (2003) · European Journal of Cancer · doi:10.1016/s0959-8049(02)00775-x · Cited by 86
“In multivariate analysis, the following QLQ-C30 variables have been associated with OS: cognitive functioning [21], physical functioning [7,10], social functioning [5]; global QOL [5,8,13] and pain [9].”
MethodHealth behaviors of head and neck cancer patients the first year after diagnosis
Duffy, S. A., Khan, M. J., Ronis, D. L., Fowler, K. E., Gruber, S. B., Wolf, G. T., & Terrell, J. E. (2007) · Head & Neck · doi:10.1002/hed.20665 · Cited by 85
“Marriage is a marker for social support, and survival rates are better for married persons and those not living alone compared with those not married or living alone.(48,49) Unmarried patients with head and neck cancer may benefit from referral to smoking cessation classes, nutritional classes, physical activity couns…”
Backgroundvan Nieuwenhuizen, A. J., Buffart, L. M., Brug, J., Leemans, C. R., & Leeuw, I. M. V. (2014) · Oral Oncology · doi:10.1016/j.oraloncology.2014.09.002 · Cited by 84
“In addition, 63% of the studies had shortcomings in the assessments of important confounders: 11 studies [38–40,43,44,46,49,50,52,54,56] did not assess comorbidity, and seven [45,49–53,55] studies did not assess smoking and alcohol consumption.”
BackgroundMethodResultInfluentialZimmaro, L., Sephton, S. E., Siwik, C. J., Phillips, K. M., Rebholz, W., Kraemer, H., Giese-Davis, J., Wilson, L. D., Bumpous, J., & Cash, E. D. (2018) · Cancer · doi:10.1002/cncr.31109 · Cited by 86
“In contrast, 2 previous studies reported nonsignificant associations between depressed mood and survival in head and neck samples.(10,11) However, the assessments may have been less sensitive(12) or may not have provided valid or reliable assessments of depression in the samples.”
ResultTwo models to investigate Medicare fraud within unsupervised databases
Musal, R. M. (2010) · Expert Systems with Applications · doi:10.1016/j.eswa.2010.06.095 · Cited by 79
van Deudekom, F. J., Schimberg, A. S., Kallenberg, M. H., Slingerland, M., van der Velden, L.-A., & Mooijaart, S. P. (2016) · Oral Oncology · doi:10.1016/j.oraloncology.2016.11.013 · Cited by 83
“Furthermore, in several studies a risk of selection bias persisted because of various reasons: excluding older patients, cognitive impaired patients or with a restriction on the functional performance [17,26,27,30,35,37,39,41,42,45,46].”
BackgroundSiddiqui, F., Pajak, T. F., Bruner, D. W., Konski, A. A., Coyne, J. C., Gwede, C. K., Garden, A. S., Spencer, S. A., Jones, C. U., & Movsas, B. (2007) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2007.06.024 · Cited by 72
Mauer, M. E. L., TAPHOORN, M. J. B., Bottomley, A., Coens, C., Efficace, F., Sanson, M., Brandes, A. A., van der Rijt, C. C. D., Bernsen, H. J. J. A., Frénay, M., et al. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2007.11.1476 · Cited by 72
Basics of tumor development and importance of human papilloma virus (HPV) for head and neck cancer
Wittekindt, C., Wagner, S., Mayer, C., & Klußmann, J. P. (2012) · PubMed Central · doi:10.3205/cto000091 · Cited by 74
“9-fold higher risk of recurrence or death during follow-up [26].”
BackgroundEmotional well‐being does not predict survival in head and neck cancer patients
Coyne, J. C., Pajak, T. F., Harris, J., Konski, A. A., Movsas, B., Ang, K. K., & Bruner, D. W. (2007) · Cancer · doi:10.1002/cncr.23080 · Cited by 68
“Total 1093 417 RTOG 9003 689 (63) 303 (37) Protocol RX STD RT arm 172 (25) 76 (25) HFX arm 168 (24) 74 (24) AFX-S arm 179 (26) 76 (25) AFX-CB arm 170 (25) 77 (25) Primary site Oral cavity 72 (10) 28 (9) Oropharynx 413 (60) 187 (62) Hypopharynx 99 (14) 32 (11) Supraglottic larynx 105 (15) 56 (18) RTOG 9111 404 (78) 114…”
Burden of treatment: Reported outcomes in a head and neck cancer survivorship clinic
Nilsen, M. L., Mady, L. J., Hodges, J. C., Wasserman‐Wincko, T., & Johnson, J. T. (2019) · The Laryngoscope · doi:10.1002/lary.27801 · Cited by 69
Results of a feasibility study for a psycho‐educational intervention in head and neck cancer
Allison, P. J., Edgar, L., Nicolau, B. F., Archer, J. A., Black, M. J., & Hier, M. (2004) · Psycho-Oncology · doi:10.1002/pon.816 · Cited by 71
Djan, R., & Penington, A. (2013) · Journal of Plastic Reconstructive & Aesthetic Surgery · doi:10.1016/j.bjps.2013.01.007 · Cited by 67
Saquib, N., Pierce, J. P., Saquib, J., Flatt, S., Natarajan, L., Bardwell, W., Patterson, R. E., Stefanick, M., Thomson, C., Rock, C. L., et al. (2011) · Psycho-Oncology · doi:10.1002/pon.1742 · Cited by 73
“This finding is in accordance with most other studies that reported either a null or weak association between mental domain of HRQOL and survival [10,11,32,33].”
ResultValue of health-related quality of life to predict disability course in multiple sclerosis
Visschedijk, M. A. J., Uitdehaag, B. M. J., Klein, M., van der Ploeg, E., Collette, E. H., Vleugels, L., Pfennings, L. E. M. A., Hoogervorst, E. L. J., van der Ploeg, H. M., & Polman, C. H. (2004) · Neurology · doi:10.1212/01.wnl.0000145769.51420.ed · Cited by 66
Osazuwa‐Peters, N., Boakye, E. A., Chen, B. Y., Tobo, B. B., & Varvares, M. A. (2017) · JAMA Otolaryngology–Head & Neck Surgery · doi:10.1001/jamaoto.2017.1880 · Cited by 68
Does Quality of Life Predict Long-term Survival in Patients With Head and Neck Cancer?
Mehanna, H. M., & Morton, R. P. (2006) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.132.1.27 · Cited by 67
“For head and neck cancer (HNC), the limited evidence available suggests that pretreatment overall QOL and long-term survival are not associated.(14) However, studies have found associations between long-term survival and individual variables, such as cognitive functioning,(14) fatigue,(15) or perceived self-efficacy.”
BackgroundResultFang, F., Tsai, W., Chien, C., Chiu, H., Wang, C., Chen, H., & Hsiung, C. (2005) · Oncology · doi:10.1159/000086982 · Cited by 66
Bonnetain, F., Paolettí, X., Collette, S., Doffoël, M., Bouché, O., Raoul, J., Rougier, P. R., Masskouri, F., Barbare, J., & Bedenne, L. (2008) · Quality of Life Research · doi:10.1007/s11136-008-9365-y · Cited by 66
“These sites include the breast [33–35], lung [36–39], oesophagus [40–42], head and neck [43], colon [44], malignant melanoma [45], multiple myeloma [46], ovary [47], and malignant glioma [48].”
BackgroundGaubatz, M. E., Bukatko, A. R., Simpson, M. C., Polednik, K. M., Boakye, E. A., Varvares, M. A., & Osazuwa-Peters, N. (2018) · Oral Oncology · doi:10.1016/j.oraloncology.2018.12.023 · Cited by 66
Impact of Smoking on Cancer Stage at Diagnosis
Kobrinsky, N. L., Klug, M. G., Hokanson, P. J., Sjolander, D. E., & Burd, L. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.05.110 · Cited by 65
Impact of cancer occurrence on health-related quality of life: a longitudinal pre-post assessment.
Boini, S., Briançon, S., Guillemin, F., Galan, P., & Herçberg, S. (2004) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-2-4 · Cited by 65
Oskam, I. M., Leeuw, I. M. V., Aaronson, N. K., Kuik, D. J., de Bree, R., Doornaert, P., Langendijk, J. A., & Leemans, C. R. (2010) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2010.02.005 · Cited by 65
“[22] studied a cohort of 208 head and neck cancer patients treated by various modalities and reported that pre-treatment cognitive functioning predicted tumor recurrence and survival, next to tumor stage, radical surgery and marital status.”
BackgroundResultMarital status and stage at diagnosis of cutaneous melanoma
McLaughlin, J. M., Fisher, J. L., & Paskett, E. D. (2010) · Cancer · doi:10.1002/cncr.25726 · Cited by 64
“Being married provides a survival advantage to those with cancer, including melanoma.(29-33) Researchers have hypothesized that the advantage of marriage may result from an immunologic benefit of psychosocial support associated with marriage or from spousal support to follow-through with treatment.”
BackgroundPersistent posttreatment depressive symptoms in patients with head and neck cancer
Karnell, L. H., Funk, G. F., Christensen, A. J., Rosenthal, E. L., & Magnuson, J. S. (2005) · Head & Neck · doi:10.1002/hed.20370 · Cited by 61
Bozec, A., Demez, P. H., Gal, J., Chamorey, E., Louis, M.-Y., Blanchard, D., Raucourt, D. D., Mérol, J., Brenet, E., Dassonville, O., et al. (2017) · Surgical Oncology · doi:10.1016/j.suronc.2017.11.005 · Cited by 61
“In this regard, in most QoL studies on head and neck cancer patients, including the above-mentioned de Graeff study, fatigue remains the main general symptom long-term after treatment, particularly in patients receiving RT þ CT [6,8,9].”
BackgroundResultThe Common Data Elements for Cancer Research: Remarks on Functions and Structure
Brandt, C., & Nadkarni, P. (2006) · Methods of Information in Medicine · doi:10.1055/s-0038-1634121 · Cited by 60
“(Psychiatry forms used in cancer research include the Center for Epidemiologic Studies Depression Scale (CES-D), which has been used for evaluation of reactive depression following disfiguring surgery for head and neck cancers [21, 22].”
MethodExplaining Socioeconomic Status Effects in Laryngeal Cancer
Groome, P. A., Schulze, K. M., Keller, S., Mackillop, W. J., O’Sullivan, B., Irish, J. C., Bissett, R. J., Dixon, P. F., Eapen, L. J., Gulavita, S. P. P., et al. (2006) · Clinical Oncology · doi:10.1016/j.clon.2005.12.010 · Cited by 59
Rogers, L. Q., Courneya, K. S., Robbins, K. T., Rao, K., Malone, J. P., Seiz, A., Reminger, S. L., Markwell, S. J., & Burra, V. (2008) · Head & Neck · doi:10.1002/hed.20873 · Cited by 59
Ledeboer, Q. C. P., van der Velden, L. A., de Boer, M. F., Feenstra, L., & Pruyn, J. F. A. (2005) · Clinical Otolaryngology · doi:10.1111/j.1365-2273.2005.01035.x · Cited by 58
Kobayashi, K., Morita, S., Shimonagayoshi, M., Kobayashi, M., Fujiki, Y., Uchida, Y., & Yamaguchi, K. (2007) · Psycho-Oncology · doi:10.1002/pon.1278 · Cited by 57
Current State-of-the-Art for Concurrent Chemoradiation
Bernier, J. (2008) · Seminars in Radiation Oncology · doi:10.1016/j.semradonc.2008.09.002 · Cited by 56
Pierre, C. S., Dassonville, O., Chamorey, E., Poissonnet, G., Ettaiche, M., Santini, J., Peyrade, F., Bénézery, K., Sudaka, A., & Bozec, A. (2013) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-013-2592-z · Cited by 55
“Nevertheless, in most head and neck cancer QoL studies, men achieved better QoL scores than women [12, 28].”
BackgroundResultRosenquist, K., Wennerberg, J. P., Annertz, K., Schildt, E., Hansson, B. G., Bladström, A., & Andersson, G. (2007) · Acta Oto-Laryngologica · doi:10.1080/00016480601110162 · Cited by 55
“[17], smoking and drinking were not predictive of recurrence and survival.”
BackgroundResultInfluentialRehabilitation: Long-Term Physical and Functional Changes Following Treatment
Eades, M., Chasen, M. R., & Bhargava, R. (2009) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2009.05.006 · Cited by 54
Quality of life predicts survival in patients with non-small cell lung cancer
Li, T., Li, C., Tseng, C.-H., Lin, K.-S., Yang, S.-Y., Chen, C., Hsia, T., Lee, Y.-D., & Lin, C. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-790 · Cited by 53
“[20-22], hepatocellular cancer [23], and head and neck cancer [24].”
BackgroundThe association of psycho‐social factors and survival in head and neck cancer
Mehanna, H. M., de Boer, M. F., & Morton, R. P. (2008) · Clinical Otolaryngology · doi:10.1111/j.1749-4486.2008.01666.x · Cited by 53
Sociodemographic disparities in choice of therapy and survival in advanced laryngeal cancer
Saini, A. T., Genden, E. M., & Megwalu, U. C. (2015) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2015.10.004 · Cited by 52
“identified married status as a positive prognostic factor in patients with squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx [18].”
BackgroundInfluentialChanges in quality of life of head-and-neck cancer patients following postoperative radiotherapy
Fang, F., Chien, C., Kuo, S.-C., Chiu, H., & Wang, C. (2004) · Acta Oncologica · doi:10.1080/02841860410018430 · Cited by 52
“EORTC QLQ-C30 Global quality of life 50 (21) 51 (20) /1 (23) NS Physical functioning 80 (17) 82 (15) /2 (22) NS Emotional functioning 77 (18) 78 (17) /1 (21) NS Cognitive functioning 82 (18) 79 (19) /3 (24) NS Social functioning 74 (24) 73 (22) /1 (27) NS Role functioning 80 (23) 82 (21) /2 (31) NS Fatigue 34 (19) 31…”
InfluentialEichhorst, B. F., Busch, R. M., Obwandner, T., Kuhn-Hallek, I., Herschbach, P., & Hallek, M. J. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.05.6929 · Cited by 51
Fang, F., Tsai, W., Chien, C., Chen, H., Hsu, H., Huang, T., Lee, T.-F., Huang, H., & Lee, C. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2010.28.8324 · Cited by 51
Saxena, P. P., Unnikrishnan, B., Rathi, P., Kotian, H., & Reshmi, B. (2018) · Clinical Epidemiology and Global Health · doi:10.1016/j.cegh.2018.08.007 · Cited by 50
“Studies have shown an increase in the incidence of HPV in past two decades.(23,24) Also seen from the table is the fact that the patients who underwent treatment like Chemo-radiation or Surgery followed by adjuvant chemo-radiation tend to have a better survival.”
BackgroundPatient-Reported Outcomes and Survivorship in Radiation Oncology: Overcoming the Cons
Siddiqui, F., Liu, A. K., Bruner, D. W., & Movsas, B. (2014) · Journal of Clinical Oncology · doi:10.1200/jco.2014.55.0707 · Cited by 50
Association Between Cognitive Function and Quality of Life in Patients With Head and Neck Cancer
Williams, A. M., Lindholm, J., Cook, D. M., Siddiqui, F., Ghanem, T., & Chang, S. S. (2017) · JAMA Otolaryngology–Head & Neck Surgery · doi:10.1001/jamaoto.2017.2014 · Cited by 46
Jansen, F., Leeuw, I. V. V.-D., Cuijpers, P., Leemans, C., Waterboer, T., Pawlita, M., Penfold, C., Thomas, S., Waylen, A., & Ness, A. (2018) · Psycho-Oncology · doi:10.1002/pon.4816 · Cited by 42
What's Love Got to do with it? Marital status and survival of head and neck cancer
Osazuwa‐Peters, N., Christopher, K. M., Cass, L. M., Massa, S. T., Hussaini, A. S., Behera, A., Walker, R. J., & Varvares, M. A. (2019) · European Journal of Cancer Care · doi:10.1111/ecc.13022 · Cited by 48
Teaching head and neck cancer patients coping strategies: results of a feasibility study
Allison, P. J., Nicolau, B. F., Edgar, L., Archer, J. A., Black, M. J., & Hier, M. (2004) · Oral Oncology · doi:10.1016/j.oraloncology.2003.11.008 · Cited by 48
Meulen, I. C., May, A. M., Ros, W. J. G., Oosterom, M., Hordijk, G.-J., Koole, R., & Leeuw, J. R. J. (2013) · The Oncologist · doi:10.1634/theoncologist.2012-0299 · Cited by 45
Self-citationAn International Comparison of Breast Cancer Survival
Gorey, K. M., Kliewer, E. V., Holowaty, E. J., Laukkanen, E., & Ng, E. (2003) · Annals of Epidemiology · doi:10.1016/s1047-2797(02)00259-4 · Cited by 45
Health‐related quality of life as a prognostic factor in patients with advanced cancer
Steel, J. L., Geller, D. A., Robinson, T. L., Savkova, A., Brower, D., Marsh, J. W., & Tsung, A. (2014) · Cancer · doi:10.1002/cncr.28902 · Cited by 44
Racial disparities in oropharyngeal cancer survival
Megwalu, U. C., & Ma, Y. (2016) · Oral Oncology · doi:10.1016/j.oraloncology.2016.12.015 · Cited by 43
Xu, C., Chen, Y., Liu, X., Tang, L., Chen, L., Mao, Y., Zhang, Y., Guo, R., Zhou, G., Li, W., et al. (2017) · Cancer Science · doi:10.1111/cas.13250 · Cited by 43
Rohde, R. L., Boakye, E. A., Challapalli, S. D., Patel, S. H., Geneus, C. J., Tobo, B. B., Simpson, M. C., Mohammed, K. A., Deshields, T. L., Varvares, M. A., et al. (2018) · Psycho-Oncology · doi:10.1002/pon.4893 · Cited by 43
Tarsitano, A., Pizzigallo, A., Ballone, E., & Marchetti, C. (2012) · Oral Surgery Oral Medicine Oral Pathology and Oral Radiology · doi:10.1016/j.oooo.2012.06.022 · Cited by 41
Østhus, A. A., Aarstad, A. K. H., Olofsson, J. S., & Aarstad, H. J. (2011) · Clinical Otolaryngology · doi:10.1111/j.1749-4486.2011.02342.x · Cited by 40
Dolan, R. T., Butler, J. S., Murphy, S. M., & Cronin, K. J. (2011) · Annals of The Royal College of Surgeons of England · doi:10.1308/003588412x13171221498749 · Cited by 40
Anstey, K. J., Mack, H. A., & von Sanden, C. (2006) · European Psychologist · doi:10.1027/1016-9040.11.3.182 · Cited by 38
Depression and Oropharynx Cancer Outcome
Shinn, E. H., Valentine, A. D., Jethanandani, A., Basen-Engquist, K. M., Fellman, B. M., Urbauer, D. L., Atkinson, E. N., Yusuf, S. W., Lenihan, D. J., Woods, M. L., et al. (2015) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000256 · Cited by 38
“(32) followed up 208 patients for 45 months and found that distress was not related to survival or to recurrence after adjusting for sociodemographic factors, smoking, disease stage, disease site, type of cancer treatment, and functional status.”
BackgroundHecker, D. M., Wiens, J. P., Cowper, T. R., Eckert, S. E., Gitto, C. A., Jacob, R. F., Mahanna, G. K., Turner, G. E., Potts, A., Logan, H. L., et al. (2002) · Journal of Prosthetic Dentistry · doi:10.1067/mpr.2002.128036 · Cited by 37
Metadata
- Authors
- de Graeff, A., de Leeuw, J. R. J., Ros, W. J. G., Hordijk, G. J., Blijham, G. H., & Winnubst, J. A. M.
- Affiliations
- University Medical Center Utrecht (NL)
- ORCID
- Ros, W.J.G
- Venue
- European Journal of Cancer
- Publisher
- Elsevier BV
- Published
- 2001-02
- Volume
- 37
- Issue
- 3
- Pages
- 332-339
- ISSN
- 0959-8049 (ISSN-L)
- OpenAlex
- W2080391410
- Cited by
- 199
- References
- 51
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 6 · 2023: 3 · 2022: 12 · 2021: 2 · 2020: 3 · 2019: 7 · 2018: 9 · 2017: 8 · 2016: 7 · 2015: 8 · 2014: 12 · 2013: 7 · 2012: 11
- FWCI
- 8.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Cancer (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Inflammatory Biomarkers in Disease Prognosis
- Keywords
- head and neck cancer, quality of life, prognostic factors, recurrence, survival, sociodemographic factors, marital status, cognitive function, mood, depression, smoking, alcohol consumption, socioeconomic status, EORTC QLQ-H&N35, EORTC QLQ-C30, social support
- MeSH terms
- Alcohol Drinking, Female, Head and Neck Neoplasms, Humans, Male, Neoplasm Recurrence, Local, Prognosis, Prospective Studies, Quality of Life, Risk Factors, Smoking, Socioeconomic Factors, Multivariate Analysis, Survival Analysis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
