CoChat
Sign Up
Cited by 184Estrogen and related hormone effectsReceptor Mechanisms and SignalingAdrenal Hormones and Disorders

The DOI matches its Crossref record; 74 of the 77 references it cites were found in a registry or an index.

Nongenomic Membrane Actions of Glucocorticoids in Vertebrates

Borski, Russell J.·2000·Trends in Endocrinology & Metabolism
DOI 10.1016/s1043-2760(00)00325-8
Open this paper in CoChat — free account

Abstract

For decades, it was widely assumed that glucocorticoids (GCs) work solely through changes in gene expression to exert their physiological actions, a process that normally takes several hours to occur. However, recent evidence indicates that GCs might also act at the membrane through specific receptors to exert multiple rapid effects on various tissues and cells. GCs modulate hormone secretion, neuronal excitability, behavior, cell morphology, carbohydrate metabolism and other processes within seconds or minutes. These early actions occur independent of the genome and are transduced by the same biochemical effector pathways responsible for mediating rapid responses to neurotransmitters. The biological significance of most rapid GC effects are not well understood, but many might be related to the important functions that this hormone plays in modulating stress responses.

Overview

Integrity signals

Registry

Crossref · 10.1016/s1043-2760(00)00325-8

Cites

74 of 74 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 77 references

Research works printed but not linked: 2

  1. Chen, 1999, Non-genomic mechanism of glucocorticoid's rapid action on neurons-membrane receptor hypothesis, Prog. Nat. Sci., 9, 81
  2. Borski, 1998, Cortisol rapidly reduces prolactin release through a nongenomic, membrane-associated action involving the calcium and cAMP messenger systems: the fish PRL cell model system. First International Meeting of Rapid Responses to Steroid Hormones, Exp. Clin. Endocrinol. Diabetes, 106, A39

Cited by

Sorted by citations

See all 184

Related

Metadata

Authors
Borski, R. J.
Affiliations
North Carolina State University (US)
Corresponding author
Borski, Russell J.
ORCID
Borski, Russell J.
Venue
Trends in Endocrinology & Metabolism
Publisher
Elsevier BV
Published
2000-12
Volume
11
Issue
10
Pages
427-436
ISSN
1043-2760 (ISSN-L)
DOI
10.1016/s1043-2760(00)00325-8
OpenAlex
W2135070639
Cited by
184
References
77
Citations by year
2026: 3 · 2024: 5 · 2023: 1 · 2022: 4 · 2021: 2 · 2020: 2 · 2019: 10 · 2018: 4 · 2017: 2 · 2016: 6 · 2015: 3 · 2014: 6 · 2013: 5 · 2012: 8
FWCI
1.47
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Trends in Endocrinology and Metabolism (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
glucocorticoids, non-genomic steroid action, membrane steroid receptors, stress response, neuronal excitability, behavior, carbohydrate metabolism, hormone secretion, cell morphology
MeSH terms
Animals, Glucocorticoids, Humans, Membranes, Vertebrates

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review