A Novel Duodenal Iron-Regulated Transporter, IREG1, Implicated in the Basolateral Transfer of Iron to the Circulation

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., & Hediger, M. A. (1997) · Nature · doi:10.1038/41343 · Cited by 3,166

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress.

Hentze, M. W., & Kühn, L. C. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.16.8175 · Cited by 1,292

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

Fleming, M. D., Trenor, C. C., Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F., & Andrews, N. C. (1997) · Nature Genetics · doi:10.1038/ng0897-383 · Cited by 1,159

Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

Vulpe, C. D., Kuo, Y.-M., Murphy, T. L., Cowley, L., Askwith, C., Libina, N., Gitschier, J., & Anderson, G. J. (1999) · Nature Genetics · doi:10.1038/5979 · Cited by 1,084

Nramp 2 is mutated in the anemic Belgrade ( b ) rat: Evidence of a role for Nramp2 in endosomal iron transport

Fleming, M. D., Romano, M. A., Su, M. A., Garrick, L. M., Garrick, M. D., & Andrews, N. C. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.1148 · Cited by 936

The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake.

Askwith, C., Eide, D., Van Ho, A., Bernard, P. S., Li, L., Davis-Kaplan, S., Sipe, D. M., & Kaplan, J. (1994) · Cell · doi:10.1016/0092-8674(94)90346-8 · Cited by 670

Molecular characterization of a copper transport protein in S. cerevisiae: An unexpected role for copper in iron transport

Dancis, A., Yuan, D. S., Haile, D., Askwith, C., Eide, D., Moehle, C., Kaplan, J., & Klausner, R. D. (1994) · Cell · doi:10.1016/0092-8674(94)90345-x · Cited by 659

The biochemical basis of the NADPH oxidase of phagocytes

Segal, A. W., & Abo, A. (1993) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(93)90051-n · Cited by 622

Direct Comparison of GAPDH, β-Actin, Cyclophilin, and 28S rRNA as Internal Standards for Quantifying RNA Levels under Hypoxia

Zhong, H., & Simons, J. W. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0815 · Cited by 473

Nramp2 is mutated in the anemic Belgrade (b) rat : evidence of a role for Nramp2 in endosomal iron transport

Flemming (1998) · Medical Entomology and Zoology · Cited by 412

Quantitative evaluation of expression of iron-metabolism genes in ceruloplasmin-deficient mice

Yamamoto, K., Yoshida, K., Miyagoe, Y., Ishikawa, A., Hanaoka, K., Nomoto, S., Kaneko, K., Ikeda, S., & Takeda, S. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/s0925-4439(02)00165-5 · Cited by 52

Role of duodenal iron transporters and hepcidin in patients with alcoholic liver disease

Dostalikova‐Cimburova, M., Balušíková, K., Krátká, K., Chmelíková, J., Hejda, V., Hnaníček, J., Neubauerová, J., Vránová, J., Kovár̆, J., & Horák, J. (2014) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12310 · Cited by 52

Superinfection in malaria: Plasmodium shows its iron will

Portugal, S., Drakesmith, H., & Mota, M. M. (2011) · EMBO Reports · doi:10.1038/embor.2011.213 · Cited by 55

Transmembrane protein western blotting: Impact of sample preparation on detection of SLC11A2 (DMT1) and SLC40A1 (ferroportin)

Tsuji, Y. (2020) · PLoS ONE · doi:10.1371/journal.pone.0235563 · Cited by 50

Animal models with enhanced erythropoiesis and iron absorption

Latunde-Dada, G. O., McKie, A. T., & Simpson, R. J. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2005.12.007 · Cited by 50

Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis

Ludwiczek, S., Theurl, I., Bahram, S., Schümann, K., & Weiß, G. (2005) · Journal of Cellular Physiology · doi:10.1002/jcp.20315 · Cited by 51

Tissue-specific changes in iron metabolism genes in mice following phenylhydrazine-induced haemolysis

Latunde-Dada, G. O., Vulpe, C. D., Anderson, G. J., Simpson, R. J., & McKie, A. T. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2004.06.011 · Cited by 50

Localization of iron transport and regulatory proteins in human cells

Griffiths, W. J., Kelly, A., Smith, S. J., & Cox, T. M. (2000) · QJM · doi:10.1093/qjmed/93.9.575 · Cited by 50

Cadmium induces iron deficiency anemia through the suppression of iron transport in the duodenum

Fujiwara, Y., Lee, J.-Y., Banno, H., Imai, S., Tokumoto, M., Hasegawa, T., Seko, Y., Nagase, H., & Satoh, M. (2020) · Toxicology Letters · doi:10.1016/j.toxlet.2020.07.005 · Cited by 49

Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway

Liu, C., Li, H.-H., Lin, J.-H., Chiang, M., Hsu, T.-W., Li, A. F., Yen, D. H.-T., Hsu, H., & Hung, S. (2021) · Biomolecules · doi:10.3390/biom12010048 · Cited by 49

Transgenic expression of DwMYB2 impairs iron transport from root to shoot in Arabidopsis thaliana

Chen, Y.-H., Wu, X., Ling, H., & Yang, W. (2006) · Cell Research · doi:10.1038/sj.cr.7310099 · Cited by 49

Intracellular localization and subsequent redistribution of metal transporters in a rat choroid plexus model following exposure to manganese or iron

Wang, X., Miller, D. S., & Zheng, W. (2008) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2008.02.024 · Cited by 49

Essential but toxic: Controlling the flux of iron in the body

Anderson, G. J., & Wang, F. (2011) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2011.05661.x · Cited by 51

Overdosing on iron: Elevated iron and degenerative brain disorders

D’Mello, S. R., & Kindy, M. S. (2020) · Experimental Biology and Medicine · doi:10.1177/1535370220953065 · Cited by 49

Mechanisms of cellular iron sensing, regulation of erythropoiesis and mitochondrial iron utilization

Maio, N., Zhang, D., Ghosh, M. C., Jain, A., SantaMaria, A. M., & Rouault, T. A. (2021) · Seminars in Hematology · doi:10.1053/j.seminhematol.2021.06.001 · Cited by 50

Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer’s, and Parkinson’s Diseases

Raha, A. A., Biswas, A., Henderson, J. W., Chakraborty, S., Holland, A. J., Friedland, R. P., Mukaetova-Ladinska, E. B., Zaman, S. H., & Raha‐Chowdhury, R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031060 · Cited by 52

Adaptive changes of duodenal iron transport proteins in celiac disease

Barisani, D., Parafioriti, A., Bardella, M. T., Zoller, H., Conte, D., Armiraglio, E., Trovato, C. M. C., Koch, R., & Weiß, G. (2004) · Physiological Genomics · doi:10.1152/physiolgenomics.00211.2003 · Cited by 49

Dietary iron alters waterborne copper-induced gene expression in soft water acclimated zebrafish (Danio rerio)

Craig, P. M., Galus, M., Wood, C. M., & McClelland, G. B. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90581.2008 · Cited by 49

Iron Loading Increases Ferroportin Heterogeneous Nuclear RNA and mRNA Levels in Murine J774 Macrophages

Aydemir, F., Jenkitkasemwong, S., Gulec, S., & Knutson, M. D. (2009) · The Journal of Nutrition · doi:10.3945/jn.108.094052 · Cited by 49

The Iron Metabolism with a Specific Focus on the Functioning of the Nervous System

Kulaszyńska, M., Kwiatkowski, S., & Skonieczna‐Żydecka, K. (2024) · Biomedicines · doi:10.3390/biomedicines12030595 · Cited by 54

Pleiotropic actions of iron balance in diabetes mellitus

Wang, X., Fang, X., & Wang, F. (2014) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-014-9303-y · Cited by 49

Factors influencing disease phenotype and penetrance in HFE haemochromatosis

Rochette, J., Gac, G. L., Lassoued, K., Férec, C., & Robson, K. (2010) · Human Genetics · doi:10.1007/s00439-010-0852-1 · Cited by 52

New perspectives on the regulation of iron absorption via cellular zinc concentrations in humans

Knez, M., Graham, R. D., Welch, R. M., & Stangoulis, J. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1050483 · Cited by 50

Iron in Alzheimer’s Disease: From Physiology to Disease Disabilities

Pal, A., Cerchiaro, G., Rani, I., Ventriglia, M., Rongioletti, M. C. A., Longobardi, A., & Squitti, R. (2022) · Biomolecules · doi:10.3390/biom12091248 · Cited by 49

Iron and copper homeostasis and intestinal absorption using the Caco2 cell model

Linder, M. C., Zerounian, N. R., Moriya, M., & Malpe, R. (2003) · BioMetals · doi:10.1023/a:1020729831696 · Cited by 49

Pathogenesis of hereditary hemochromatosis

Fleming, R. E., Britton, R. S., Waheed, A., Sly, W. S., & Bacon, B. R. (2004) · Clinics in Liver Disease · doi:10.1016/j.cld.2004.06.004 · Cited by 48

Molecular and clinical correlates in iron overload associated with mutations in ferroportin.

Domenico, I. D., Ward, D. M., Nemeth, E., Ganz, T., Corradini, E., Ferrara, F., Musci, G., Pietrangelo, A., & Kaplan, J. (2006) · PubMed · Cited by 48

Placental ceruloplasmin homolog is regulated by iron and copper and is implicated in iron metabolism

Danzeisen, R., Fosset, C., Chariana, Z., Page, K., David, S., & McArdle, H. J. (2002) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00019.2001 · Cited by 48

Apical location of ferroportin 1 in airway epithelia and its role in iron detoxification in the lung

Yang, F., Haile, D. J., Wang, X., Dailey, L. A., Stonehuerner, J. G., & Ghio, A. J. (2005) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00456.2004 · Cited by 47

Moonlighting cell surface GAPDH recruits Apo Transferrin to effect iron egress from mammalian cells

Sheokand, N., Malhotra, H., Kumar, S., Tillu, V. A., Chauhan, A. S., Raje, C. I., & Raje, M. (2014) · Journal of Cell Science · doi:10.1242/jcs.154005 · Cited by 49

The Intestinal Heme Transporter Revealed

Rouault, T. A. (2005) · Cell · doi:10.1016/j.cell.2005.08.027 · Cited by 47

Transcriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2α) in intestinal epithelial cells

Xie, L., & Collins, J. F. (2011) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00023.2011 · Cited by 48

Perspective: What Makes It So Difficult to Mitigate Worldwide Anemia Prevalence?

Schümann, K., & Solomons, N. W. (2017) · Advances in Nutrition · doi:10.3945/an.116.013847 · Cited by 48

Physiological functions of ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury

Wang, X., Zheng, X., Zhang, J., Zhao, S., Wang, Z., Wang, F., Shang, W., Barasch, J. M., & Qiu, A. (2018) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00072.2018 · Cited by 50

Review article: iron disturbances in chronic liver diseases other than haemochromatosis – pathogenic, prognostic, and therapeutic implications

Czaja, A. J. (2019) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.15173 · Cited by 47

Role of Iron in the Molecular Pathogenesis of Diseases and Therapeutic Opportunities

Abbasi, U., Abbina, S., Gill, A., Takuechi, L. E., & Kizhakkedathu, J. N. (2021) · ACS Chemical Biology · doi:10.1021/acschembio.1c00122 · Cited by 48

Expression of the Hereditary Hemochromatosis Protein HFE Increases Ferritin Levels by Inhibiting Iron Export in HT29 Cells

Davies, P. S., & Enns, C. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400537200 · Cited by 47

The molecular regulation of iron metabolism

Donovan, A., & Andrews, N. C. (2004) · The Hematology Journal · doi:10.1038/sj.thj.6200540 · Cited by 48

Ferroportin/IREG-1/MTP-1/SLC40A1 modulates the uptake of iron at the apical membrane of enterocytes

Thomas, C. (2003) · Gut · doi:10.1136/gut.53.1.44 · Cited by 48

Coordinate expression and localization of iron and zinc transporters explain iron–zinc interactions during uptake in Caco-2 cells: implications for iron uptake at the enterocyte

Iyengar, V., Pullakhandam, R., & Nair, K. M. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2011.06.008 · Cited by 46

An Aluminum-Inducible IREG Gene is Required for Internal Detoxification of Aluminum in Buckwheat

Yokosho, K., Yamaji, N., Mitani‐Ueno, N., Shen, R. F., & Feng, J. X. (2016) · Plant and Cell Physiology · doi:10.1093/pcp/pcw065 · Cited by 46

The Role of Iron Metabolism in Lung Inflammation and Injury

Kim, J. (2012) · Journal of Allergy & Therapy · doi:10.4172/2155-6121.s4-004 · Cited by 48

The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system

Reuben, A., Chung, J. W., Lapointe, R., & Santos, M. M. (2017) · Immunity Inflammation and Disease · doi:10.1002/iid3.158 · Cited by 46

The role of hepcidin and ferroportin in iron absorption.

Oates, P. S. (2007) · PubMed · doi:10.14670/hh-22.791 · Cited by 46

A genetic view of iron homeostasis

Andrews, N. C. (2002) · Seminars in Hematology · doi:10.1053/shem.2002.35632 · Cited by 46

Ferroptosis and Its Emerging Role in Pre-Eclampsia

Chen, Z., Gan, J., Zhang, M., Du, Y., & Zhao, H. (2022) · Antioxidants · doi:10.3390/antiox11071282 · Cited by 46

Impact of ferroptosis on preeclampsia: A review

Shan, Y., Guan, C., Wang, J., Qi, W., Chen, A., & Liu, S. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115466 · Cited by 47

Non-HFE hemochromatosis: Pathophysiological and diagnostic aspects

Bardou‐Jacquet, E., Ali, Z. B., Beaumont-Epinette, M.-P., Loréal, O., Jouanolle, A., & Brissot, P. (2013) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2013.11.003 · Cited by 47

Modelling Systemic Iron Regulation during Dietary Iron Overload and Acute Inflammation: Role of Hepcidin-Independent Mechanisms

Enculescu, M., Metzendorf, C., Sparla, R., Hahnel, M. J., Bode, J. G., Muckenthaler, M. U., & Legewie, S. (2017) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005322 · Cited by 46

Iron Deficiency in Pulmonary Arterial Hypertension: A Deep Dive into the Mechanisms

Quatredeniers, M., Mendes‐Ferreira, P., Santos‐Ribeiro, D., Nakhleh, M. K., Ghigna, M., Cohen‐Kaminsky, S., & Perros, F. (2021) · Cells · doi:10.3390/cells10020477 · Cited by 45

Pumping iron: the strange partnership of the hemochromatosis protein, a class I MHC homolog, with the transferrin receptor

Enns, C. A. (2001) · Traffic · doi:10.1034/j.1600-0854.2001.020303.x · Cited by 45

Effects of copper and ceruloplasmin on iron transport in the Caco 2 cell intestinal model

Zerounian, N. R., & Linder, M. C. (2002) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(01)00205-4 · Cited by 46

Gastrointestinal function, divalent metal transporter-1 expressionand intestinal iron absorption

Oates, P. S., Trinder, D., & Morgan, E. H. (2000) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s004240000319 · Cited by 45

Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1

Núñez, M. T., Tapia, V., Rojas, A., Aguirre, P., Gómez, F., & Nualart, F. (2010) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00168.2009 · Cited by 44

Angiotensin II-Induced Regulation of the Expression and Localization of Iron Metabolism-Related Genes in the Rat Kidney

Ishizaka, N., Saito, K., FURUTA, K., Matsuzaki, G., Koike, K., Noiri, E., & Nagai, R. (2007) · Hypertension Research · doi:10.1291/hypres.30.195 · Cited by 44

Distribution of Ferroportin1 Protein in Different Regions of Developing Rat Brain

Jiang, D. H., Ke, Y., Cheng, Y. Z., Ho, K. P., & Qian, Z. (2002) · Developmental Neuroscience · doi:10.1159/000065687 · Cited by 44

Health Implications of Iron Overload: the Role of Diet and Genotype

Heath, A. M., & Fairweather‐Tait, S. J. (2003) · Nutrition Reviews · doi:10.1301/nr.2003.febr.45-62 · Cited by 44

Expression of iron regulatory genes in a rat model of hepatocellular carcinoma

Holmström, P., Gåfvels, M. E., Eriksson, L. C., Dzikaite, V., Hultcrantz, R. W., Eggertsen, G., & Stal, P. I. (2006) · Liver International · doi:10.1111/j.1478-3231.2006.01316.x · Cited by 44

Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages

Auriac, A., Willemetz, A., & Canonne‐Hergaux, F. (2010) · Haematologica · doi:10.3324/haematol.2009.019992 · Cited by 47

Iron Deficiency and Anemia

Ramakrishnan, U., & Semba, R. D. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-464-3_16 · Cited by 44

Inflammation-induced up-regulation of hepcidin and down-regulation of ferroportin transcription are dependent on macrophage polarization

Agoro, R., & Mura, C. (2016) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2016.07.006 · Cited by 44

ATP-driven copper transport across the intestinal brush border membrane

Knöpfel, M., Smith, C. P., & Solioz, M. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.03.023 · Cited by 44

Redox control of iron regulatory proteins

Fillebeen, C., & Pantopoulos, K. (2002) · Redox Report · doi:10.1179/135100002125000136 · Cited by 44

A role for tumour necrosis factor α in human small bowel iron transport

Sharma, N., Laftah, A. H., Brookes, M., Cooper, B. T., Iqbal, T. H., & Tselepis, C. (2005) · Biochemical Journal · doi:10.1042/bj20050256 · Cited by 44

Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors and Iron Metabolism

Ogawa, C., Tsuchiya, K., & Maeda, K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24033037 · Cited by 45

Heterogenous distribution of ferroportin-containing neurons in mouse brain

Boserup, M. W., Lichota, J., Haile, D. J., & Moos, T. (2011) · BioMetals · doi:10.1007/s10534-010-9405-2 · Cited by 44

Hepcidin and the iron enigma in HCV infection

Georgopoulou, U., Dimitriadis, A., Foka, P., Karamichali, E., & Mamalaki, A. (2014) · Virulence · doi:10.4161/viru.28508 · Cited by 43

Ferroportin Diseases: Functional Studies, a Link Between Genetic and Clinical Phenotype

Détivaud, L., Island, M., Jouanolle, A., Ropert, M., Bardou‐Jacquet, E., Lan, C. L., Mosser, A., Leroyer, P., Deugnier, Y., David, V., et al. (2013) · Human Mutation · doi:10.1002/humu.22396 · Cited by 47

Systemic iron status

Beard, J., & Han, O. (2008) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2008.09.005 · Cited by 45

Ferroptosis in Neurological Disease

David, S., Ryan, F., Jhelum, P., & Kroner, A. (2022) · The Neuroscientist · doi:10.1177/10738584221100183 · Cited by 43

Iron Homeostasis in the CNS: An Overview of the Pathological Consequences of Iron Metabolism Disruption

Porras, C. A.-M., & Rouault, T. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094490 · Cited by 44

Ascorbic Acid Offsets the Inhibitory Effect of Bioactive Dietary Polyphenolic Compounds on Transepithelial Iron Transport in Caco-2 Intestinal Cells1,2

Kim, E., Ham, S., Bradke, D., Ma, Q., & Han, O. (2011) · Journal of Nutrition · doi:10.3945/jn.110.134031 · Cited by 42

Hepatic iron overload in alcoholic liver disease: why does it occur and what is its role in pathogenesis?

Rouault, T. A. (2003) · Alcohol · doi:10.1016/s0741-8329(03)00102-2 · Cited by 42

An IRP-like protein from Plasmodium falciparum binds to a mammalian iron-responsive element

Loyevsky, M., LaVaute, T. M., Allerson, C. R., Stearman, R. S., Kassim, O. O., Cooperman, S. S., Gordeuk, V. R., & Rouault, T. A. (2001) · Blood · doi:10.1182/blood.v98.8.2555 · Cited by 42

Molecular analysis of iron overload in β2-microglobulin-deficient mice

Muckenthaler, M. U., Rodrigues, P., Macedo, M. G., Miñana, B., Brennan, K., Cardoso, E. M., Hentze, M. W., & de Sousa, M. A. B. (2004) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2004.05.003 · Cited by 43

The transcytosis of divalent metal transporter 1 and apo-transferrin during iron uptake in intestinal epithelium

Ma, Y., Specian, R. D., Yeh, K., YEH, M. K. Y., Rodriguez‐Paris, J., & Glass, J. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00005.2002 · Cited by 42

Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice

Mok, H., Mendoza, M., Prchal, J. T., Balogh, P., & Schumacher, A. (2004) · Development · doi:10.1242/dev.01342 · Cited by 43

Iron Absorption: Molecular and Pathophysiological Aspects

Correnti, M., Gammella, E., Cairo, G., & Recalcati, S. (2024) · Metabolites · doi:10.3390/metabo14040228 · Cited by 48

Iron delocalisation in the pathogenesis of malarial anaemia

Nweneka, C. V., Doherty, C. P., Cox, S. E., & Prentice, A. M. (2009) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/j.trstmh.2009.08.007 · Cited by 43

Toll-Like Receptor Signal Adaptor Protein MyD88 Is Required for Sustained Endotoxin-Induced Acute Hypoferremic Response in Mice

Layoun, A., Huang, H., Calvé, A., & Santos, M. M. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.01.046 · Cited by 43

Hamp1 but not Hamp2 regulates ferroportin in fish with two functionally distinct hepcidin types

Neves, J. V., Ramos, M. F., Moreira, A. C., Silva, T., Gomes, M. S., & Rodrigues, P. (2017) · Scientific Reports · doi:10.1038/s41598-017-14933-5 · Cited by 41

Regulating ferroportin‐1 and transferrin receptor‐1 expression: A novel function of hydrogen sulfide

Zhang, M., Yang, G., Zhou, Y., Qian, C., Mu, M., Ke, Y., & Qian, Z. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27431 · Cited by 41

Medicago truncatula Ferroportin2 mediates iron import into nodule symbiosomes

Escudero, V., Abreu, I., Tejada‐Jiménez, M., Rosa‐Núñez, E., Quintana, J., Prieto, R. I., Larue, C., Wen, J., Villanova, J., Mysore, K. S., et al. (2020) · New Phytologist · doi:10.1111/nph.16642 · Cited by 41

Melatonin: Potential avenue for treating iron overload disorders

Yang, J., Tang, Q., & Zeng, Y. H. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101717 · Cited by 41

FET3P, ceruloplasmin, and the role of copper in iron metabolism

Kosman, D. J. (2002) · Advances in protein chemistry · doi:10.1016/s0065-3233(02)60055-5 · Cited by 41

A Japanese Family with Ferroportin Disease Caused by a Novel Mutation of SLC40A1 Gene: Hyperferritinemia Associated with a Relatively Low Transferrin Saturation of Iron

Koyama, C., Wakusawa, S., Hayashi, H., Ueno, T., SUZUKI, R., Yano, M., Saito, H., & OKAZAKI, T. (2005) · Internal Medicine · doi:10.2169/internalmedicine.44.990 · Cited by 41

Non‐haem iron transport in the rat proximal colon

Johnston, K. L., Johnson, D., Marks, J., Srai, S. K., Debnam, E. S., & Sharp, P. (2005) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2006.01585.x · Cited by 41

Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase‐1 deficiency

Kartikasari, A. E. R., Wagener, F. A. D. T. G., Yachie, A., Wiegerinck, E. T. G., Kemna, E., & Winkels, D. W. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00494.x · Cited by 41

Heme Utilization in the Caenorhabditis elegans Hypodermal Cells Is Facilitated by Heme-responsive Gene-2

Chen, C., Samuel, T. K., Krause, M., Dailey, H. A., & Hamza, I. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.307694 · Cited by 43

Increased Hepatic Accumulation of Ingested Cd is Associated with Upregulation of Several Intestinal Transporters in Mice Fed Diets Deficient in Essential Metals

Min, K.-S., Ueda, H., Kihara, T., & Tanaka, K. (2008) · Toxicological Sciences · doi:10.1093/toxsci/kfn146 · Cited by 41

IEC-6 Cells Are an Appropriate Model of Intestinal Iron Absorption in Rats

Thomas, C., & Oates, P. S. (2002) · Journal of Nutrition · doi:10.1093/jn/132.4.680 · Cited by 41

Transferrin receptor 1 mRNA is downregulated in placenta of hepcidin transgenic embryos

Martin, M. E., Nicolas, G., Hetet, G., Vaulont, S., Grandchamp, B., & Beaumont, C. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.08.010 · Cited by 40

Defective regulation of iron transporters leading to iron excess in the polymorphonuclear leukocytes of patients on maintenance hemodialysis

Otaki, Y., Nakanishi, T., Hasuike, Y., Moriguchi, R., Nanami, M., Hama, Y., Izumi, M., & Takamitsu, Y. (2004) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2004.02.016 · Cited by 40

Role of Cellular Iron and Oxygen in the Regulation of HIV-1 Infection

Nekhai, S. A., Kumari, N., & Dhawan, S. (2013) · Future Virology · doi:10.2217/fvl.13.6 · Cited by 40

Role of ferritin and ferroportin genes in unexplained hyperferritinaemia

Cazzola, M. (2005) · Best Practice & Research Clinical Haematology · doi:10.1016/j.beha.2004.08.025 · Cited by 40

Analysis of the rainbow trout solute carrier 11 family reveals iron import ⩽ pH 7.4 and a functional isoform lacking transmembrane domains 11 and 12

Cooper, C. A., Shayeghi, M., Techau, M. E., Capdevila, D. M., MacKenzie, S. A., Durrant, C. J., & Bury, N. R. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.04.081 · Cited by 40

GGA2- and Ubiquitin-dependent Trafficking of Arn1, the Ferrichrome Transporter ofSaccharomyces cerevisiae

Kim, Y., Deng, Y., & Philpott, C. C. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-09-0861 · Cited by 40

Advancements in anemias related to chronic conditions

Guidi, G. C., & Santonastaso, C. L. (2010) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2010.264 · Cited by 39

Alteration of Iron Concentration in Alzheimer’s Disease as a Possible Diagnostic Biomarker Unveiling Ferroptosis

Ficiarà, E., Munir, Z., Boschi, S., Caligiuri, M. E., & Guiot, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094479 · Cited by 40

Expression of a recombinant IRP-like Plasmodium falciparum protein that specifically binds putative plasmodial IREs

Loyevsky, M., Mompoint, F., Yikilmaz, E., Altschul, S. F., Madden, T., Wootton, J. C., Kurantsin‐Mills, J., Kassim, O. O., Gordeuk, V. R., & Rouault, T. A. (2003) · Molecular and Biochemical Parasitology · doi:10.1016/s0166-6851(02)00278-5 · Cited by 39

Regulation of Iron Transport and Transporter Expression in Intestinal Epithelial Cells by Dietary and Humoral Agents.

Johnson, D. (2005) · Surrey Research Insight Open Access (The University of Surrey)

Intestinal expression of genes involved in iron absorption in humans

Rolfs, A., Bonkovsky, H. L., Kohlroser, J. G., McNeal, K., Sharma, A. K., Berger, U. V., & Hediger, M. A. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00371.2001 · Cited by 82

The Expression and Regulation of the Iron Transport Molecules Hephaestin and IREG1

Anderson, G. J., Frazer, D. M., McKie, A. T., Wilkins, S. J., & Vulpe, C. D. (2002) · Cell Biochemistry and Biophysics · doi:10.1385/cbb:36:2-3:137 · Cited by 36

Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1

Zoller, H., Theurl, I., Koch, R., Kaser, A., & Weiss, G. (2002) · Blood Cells, Molecules, and Diseases · doi:10.1006/bcmd.2002.0587 · Cited by 106

The SLC40 basolateral iron transporter family (IREG1/ferroportin/MTP1)

McKie, A. T., & Barlow, D. J. (2004) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-003-1102-3 · Cited by 89