Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR

Crystal structure of the nucleosome core particle at 2.8 Å resolution

Luger, K., Mäder, A. W., Richmond, R. K., Sargent, D. F., & Richmond, T. J. (1997) · Nature · doi:10.1038/38444 · Cited by 9,466

Current protocols in molecular biology

Sargent, T. (1988) · Analytical Biochemistry · doi:10.1016/0003-2697(88)90147-9 · Cited by 7,281

Histone acetylation in chromatin structure and transcription

Grunstein, M. (1997) · Nature · doi:10.1038/38664 · Cited by 2,884

The coregulator exchange in transcriptional functions of nuclear receptors

Glass, C. K., & Rosenfeld, M. G. (2000) · Genes & Development · doi:10.1101/gad.14.2.121 · Cited by 2,233

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Hörlein, A., Näär, A. M., Heinzel, T., Torchia, J., Gloss, B. R., Kurokawa, R., Ryan, A. K., Kamei, Y., Söderström, M., Glass, C. K., et al. (1995) · Nature · doi:10.1038/377397a0 · Cited by 2,072

Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome

Kornberg, R. D., & Lorch, Y. (1999) · Cell · doi:10.1016/s0092-8674(00)81958-3 · Cited by 1,833

A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

Taunton, J., Hassig, C. A., & Schreiber, S. L. (1996) · Science · doi:10.1126/science.272.5260.408 · Cited by 1,829

Histone acetylation and transcriptional regulatory mechanisms

Struhl, K. (1998) · Genes & Development · doi:10.1101/gad.12.5.599 · Cited by 1,815

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Finnin, M. S., Donigian, J. R., Cohen, A., Richon, V. M., Rifkind, R. A., Marks, P. A., Breslow, R., & Pavletich, N. P. (1999) · Nature · doi:10.1038/43710 · Cited by 1,714

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

Osborn, L., Kunkel, S. L., & Nabel, G. J. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.7.2336 · Cited by 1,583

A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation

Hess, L., Moos, V., Lauber, A. A., Reiter, W., Schuster, M. K., Hartl, N., Lackner, D. H., Boenke, T., Koren, A., Guzzardo, P. M., et al. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010376 · Cited by 38

Class-IIa Histone Deacetylase Inhibition Promotes the Growth of Neural Processes and Protects Them Against Neurotoxic Insult

Collins, L., Adriaanse, L. J., Theratile, S. D., Hegarty, S. V., Sullivan, A. M., & O’Keeffe, G. W. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8820-8 · Cited by 35

Histone Deacetylase 3 Regulates Cyclin A Stability

Vidal-Laliena, M., Gallastegui, E., Mateo, F., Martínez-Balbás, M., Pujol, M. J., & Bachs, O. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.458323 · Cited by 34

Inhibition of Hdac3 as a Strategy for Developing Novel Diabetes Therapeutics

Meier, B. C., & Wagner, B. K. (2014) · Epigenomics · doi:10.2217/epi.14.11 · Cited by 34

PC4 Coactivates MyoD by Relieving the Histone Deacetylase 4-Mediated Inhibition of Myocyte Enhancer Factor 2C

Micheli, L., Leonardi, L., Conti, F., Buanne, P., Canu, N., Caruso, M., & Tirone, F. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.6.2242-2259.2005 · Cited by 34

Distinct roles for the deacetylase domain of HDAC3 in the hippocampus and medial prefrontal cortex in the formation and extinction of memory

Alaghband, Y., Kwapis, J. L., López, A. J., White, A. O., Aimiuwu, O. V., Al-Kachak, A., Bodinayake, K. K., Oparaugo, N. C., Dang, R., Astarabadi, M., et al. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.09.001 · Cited by 34

Epigenetic Regulation by Nuclear Receptors

Green, C. D., & Han, J. J. (2011) · Epigenomics · doi:10.2217/epi.10.75 · Cited by 36

Histone Deacetylase 9: Its Role in the Pathogenesis of Diabetes and Other Chronic Diseases

Hu, S., Cho, E.-H., & Lee, J. (2020) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2019.0243 · Cited by 34

The Role of Post-Translational Acetylation and Deacetylation of Signaling Proteins and Transcription Factors after Cerebral Ischemia: Facts and Hypotheses

Demyanenko, S. V., & Sharifulina, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157947 · Cited by 33

Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin

Yue, F., Li, W., Zou, J., Chen, Q., Xu, G., Huang, H. W., Xu, Z., Zhang, S., Gallinari, P., Wang, F., et al. (2015) · Aging · doi:10.18632/aging.100818 · Cited by 34

Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222

Gomez‐Paloma, L., Bruno, I., Cini, E., Khochbin, S., Rodriquez, M., Taddei, M., Terracciano, S., & Sadoul, K. (2007) · ChemMedChem · doi:10.1002/cmdc.200700095 · Cited by 33

Toxicity of overexpressed MeCP2 is independent of HDAC3 activityPreprint

Koerner, M. V., FitzPatrick, L., Selfridge, J., Guy, J., Sousa, D. D., Tillotson, R., Kerr, A. R. W., Sun, Z., Lazar, M. A., Lyst, M. J., et al. (2018) · Genes & Development · doi:10.1101/gad.320325.118 · Cited by 37

Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors

Payne, N. C., & Mazitschek, R. (2022) · Cell chemical biology · doi:10.1016/j.chembiol.2022.03.002 · Cited by 33

Histone deacetylases and repression of the gonadotropin genes

Melamed, P. (2008) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2007.10.008 · Cited by 32

Assessing acetylation of NF-κB

Chen, L., & Greene, W. C. (2005) · Methods · doi:10.1016/j.ymeth.2005.03.011 · Cited by 31

IL-13 enhances mesenchymal transition of pulmonary artery endothelial cells via down-regulation of miR-424/503 in vitro

Takagi, K., Yamakuchi, M., Matsuyama, T., Kondo, K., Uchida, A., Misono, S., Hashiguchi, T., & Inoue, H. (2017) · Cellular Signalling · doi:10.1016/j.cellsig.2017.10.019 · Cited by 32

Angiokine Wisp-1 is increased in myocardial infarction and regulates cardiac endothelial signaling

Wright, L. H., Herr, D. J., Brown, S. S., Kasiganesan, H., & Menick, D. R. (2018) · JCI Insight · doi:10.1172/jci.insight.95824 · Cited by 31

Advances and Limitations of Current Epigenetic Studies Investigating Mammalian Axonal Regeneration

Palmisano, I., & Giovanni, S. D. (2018) · Neurotherapeutics · doi:10.1007/s13311-018-0636-1 · Cited by 30

Identification of NuRSERY, a new functional HDAC complex composed by HDAC5, GATA1, EKLF and pERK present in human erythroid cells

Varricchio, L., Dell’Aversana, C., Nebbioso, A., Migliaccio, G., Altucci, L., Mai, A., Grazzini, G., Bieker, J. J., & Migliaccio, A. R. (2014) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2014.02.019 · Cited by 32

Prenatal Ethanol Exposure Causes Glucose Intolerance with Increased Hepatic Gluconeogenesis and Histone Deacetylases in Adult Rat Offspring: Reversal by Tauroursodeoxycholic Acid

Yao, X., Nguyen, H. K., & Nyomba, B. L. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059680 · Cited by 30

A Fluorescence‐Lifetime‐Based Binding Assay for Class IIa Histone Deacetylases

Meyners, C., Mertens, M., Wessig, P., & Meyer‐Almes, F. (2016) · Chemistry - A European Journal · doi:10.1002/chem.201605140 · Cited by 30

The role of histone deacetylase 4 during chondrocyte hypertrophy and endochondral bone development

Chen, Z., Zhang, Z., Guo, L., Wei, X., Zhang, Y., Wang, X., & Lei, W. (2020) · Bone and Joint Research · doi:10.1302/2046-3758.92.bjr-2019-0172.r1 · Cited by 30

Disruption of HDAC4/N-CoR complex by histone deacetylase inhibitors leads to inhibition of IL-2 gene expression

Matsuoka, H., Fujimura, T., Hayashi, M., Matsuda, K., Ishii, Y., Aramori, I., & Mutoh, S. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.05.002 · Cited by 30

Competitive or noncompetitive, that's the question: research toward histone deacetylase inhibitors

Su, H. L., Altucci, L., & You, Q. (2008) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-07-2289 · Cited by 30

Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1α,25-dihydroxyvitamin D 3

Malinen, M., Ryynänen, J., Heinäniemi, M., Vaïsänen, S., & Carlberg, C. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq820 · Cited by 29

G9a inhibits MEF2C activity to control sarcomere assembly

Ow, J. R., Kala, M. P., Rao, V. K., Choi, M. H., Bharathy, N., & Taneja, R. (2016) · Scientific Reports · doi:10.1038/srep34163 · Cited by 29

Molecular imaging HDACs class IIa expression-activity and pharmacologic inhibition in intracerebral glioma models in rats using PET/CT/(MRI) with [18F]TFAHA

Laws, M. T., Bonomi, R. E., Kamal, S., Gelovani, D. J., Llaniguez, J. T., Potukutchi, S., Lu, X., Mangner, T. J., & Gelovani, J. G. (2019) · Scientific Reports · doi:10.1038/s41598-019-40054-2 · Cited by 29

The important role of histone deacetylases in modulating vascular physiology and arteriosclerosis

Zhao, T. C., Wang, Z., & Zhao, Y. (2020) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2020.04.020 · Cited by 29

Histone deacetylases in modulating cardiac disease and their clinical translational and therapeutic implications

Wang, Z., Zhao, Y., & Zhao, T. C. (2020) · Experimental Biology and Medicine · doi:10.1177/1535370220944128 · Cited by 29

Role of histone deacetylase 2 and its posttranslational modifications in cardiac hypertrophy

Eom, G. H., & Kook, H. Y. (2015) · BMB Reports · doi:10.5483/bmbrep.2015.48.3.242 · Cited by 29

A histone deacetylase inhibitor improves hypothyroidism caused by a TR 1 mutant

Kim, D., Park, J. W., Willingham, M. C., & Cheng, S.-Y. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt660 · Cited by 29

Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage

de la Vega, L., Hornung, J., Kremmer, E., Milanovic, M., & Schmitz, M. L. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt262 · Cited by 29

Histone deacetylases as new therapy targets for platinum-resistant epithelial ovarian cancer

Pchejetski, D., Alfraidi, A., Sacco, K. A., Alshaker, H. A., Muhammad, A., & Monzon, L. (2015) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-015-2064-5 · Cited by 30

Structural Biology of Human Metal-Dependent Histone Deacetylases

Schapira, M. (2011) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-21631-2_10 · Cited by 30

The Nuclear Receptor Co-repressor (N-CoR) Utilizes Repression Domains I and III for Interaction and Co-repression with ETO

Lausen, J., Cho, S., Liu, S., & Werner, M. H. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407239200 · Cited by 30

Therapeutic potential of dithiolethiones for hepatic diseases

Brooks, S. C., Brooks, J. S., Lee, W. H., Lee, M. G., & Kim, S. G. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.06.006 · Cited by 28

Mechanisms of transcription factor acetylation and consequences in hearts

Thiagarajan, D., Vedantham, S., Ananthakrishnan, R., Schmidt, A. M., & Ramasamy, R. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.08.011 · Cited by 29

Histone Deacetylase 3 Deletion in Mesenchymal Progenitor Cells Hinders Long Bone Development

Feigenson, M., Shull, L. C., Taylor, E. L., Camilleri, E. T., Riester, S. M., van Wijnen, A. J., Bradley, E. W., & Westendorf, J. J. (2017) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3236 · Cited by 28

Cinnamaldehyde, cinnamic acid, and cinnamyl alcohol, the bioactives of Cinnamomum cassia exhibit HDAC8 inhibitory activity: An In vitro and In silico study

Kaul-Ghanekar, R., Patil, M., Choudhari, A., Pandita, S., Islam, M. A., & Raina, P. (2017) · Pharmacognosy Magazine · doi:10.4103/pm.pm_389_16 · Cited by 29

Increased Abundance of Nuclear HDAC4 Impairs Neuronal Development and Long-Term Memory

Main, P., Tan, W. J., Wheeler, D. A., & Fitzsimons, H. L. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.616642 · Cited by 28

Epigenetic Regulation of Chondrocytes and Subchondral Bone in Osteoarthritis

Ball, H. C., Alejo, A. L., Kronk, T. A., Alejo, A., & Safadi, F. F. (2022) · Life · doi:10.3390/life12040582 · Cited by 29

A short N-terminal domain of HDAC4 preserves photoreceptors and restores visual function in retinitis pigmentosa

Guo, X. V., Wang, S.-B., Xu, H., Ribic, A., Mohns, E. J., Zhou, Y., Zhu, X., Biederer, T., Crair, M. C., & Chen, B. (2015) · Nature Communications · doi:10.1038/ncomms9005 · Cited by 28

Peroxisome proliferator‐activated receptor γ is inhibited by histone deacetylase 4 in cortical neurons under oxidative stress

Yang, Y., Qin, X., Liu, S., Li, J., Zhu, X., Gao, T., & Xuemin, W. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07316.x · Cited by 27

Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor

Thiagarajan, D., Ananthakrishnan, R., Zhang, J., O’Shea, K. M., Quadri, N., Li, Q., Sas, K. M., Xiao, J., Rosario, R., Pennathur, S., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.02.086 · Cited by 28

It is a complex issue: emerging connections between epigenetic regulators in drug addiction

Anderson, E. M., Penrod, R. D., Barry, S. M., Hughes, B. W., Taniguchi, M., & Cowan, C. W. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14170 · Cited by 29

Targeting downstream transcription factors and epigenetic modifications following Toll-like receptor 7/8 ligation to forestall tissue injury in anti-Ro60 associated heart block

Clancy, R. M., Markham, A. J., Reed, J. H., Blumenberg, M., Halushka, M. K., & Buyon, J. P. (2015) · Journal of Autoimmunity · doi:10.1016/j.jaut.2015.09.003 · Cited by 27

Acetyl-lysine erasers and readers in the control of pulmonary hypertension and right ventricular hypertrophy

Stratton, M. S., & McKinsey, T. A. (2014) · Biochemistry and Cell Biology · doi:10.1139/bcb-2014-0119 · Cited by 31

Advances in Label-Free Screening Approaches for Studying Sirtuin-Mediated Deacetylation

Rye, P. T., Frick, L. E., Özbal, C. C., & LaMarr, W. A. (2011) · SLAS DISCOVERY · doi:10.1177/1087057111420291 · Cited by 27

Elevated and Deregulated Expression of HDAC3 in Human Astrocytic Glial Tumours

Libý, P., Kostrouchová, M., Pohludka, M., Yilma, P., Hrabal, P., Sikora, J., Brožová, E., Kostrouchová, M., Rall, J. E., & Kostrouch, Z. (2006) · Folia Biologica · doi:10.14712/fb2006052010021 · Cited by 28

Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes

Chen, W.-B., Gao, L., Wang, J., Wang, Y.-G., Dong, Z., Zhao, J., Mi, Q., & Zhou, L. (2016) · Oncotarget · doi:10.18632/oncotarget.11295 · Cited by 27

miR‐193b‐5p regulates chondrocytes metabolism by directly targeting histone deacetylase 7 in interleukin‐1β‐induced osteoarthritis

Zhang, C., Zhang, Z., Chang, Z., Mao, G., Hu, S., Zeng, A., & Fu, M. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28545 · Cited by 30

Regulation of metastasis in colorectal adenocarcinoma: A collision between development and tumor biology

Smith, J. J., Deane, N. G., Dhawan, P., & Beauchamp, R. D. (2008) · Surgery · doi:10.1016/j.surg.2008.05.007 · Cited by 26

The multi zinc-finger protein Trps1 acts as a regulator of histone deacetylation during mitosis

Wuelling, M., Pasdziernik, M., Moll, C. N., Thiesen, A. M., Schneider, S., Johannes, C., & Vortkamp, A. (2013) · Cell Cycle · doi:10.4161/cc.25267 · Cited by 26

Role of HDACs in cardiac electropathology: Therapeutic implications for atrial fibrillation

Brundel, B. J. J. M., Li, J., & Zhang, D. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2019.03.006 · Cited by 26

HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages

Gupta, K. D., Ramnath, D., von Pein, J. B., Curson, J. E. B., Wang, Y., Abrol, R., Kakkanat, A., Moradi, S. V., Gunther, K. S., Murthy, A. M. V., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2212813120 · Cited by 25

Estrogen-Dependent Dynamic Profile of eNOS-DNA Associations in Prostate Cancer

Nanni, S., Aiello, A., Re, A., Guffanti, A., Benvenuti, V., Colussi, C., Castro‐Vega, L. J., Felsani, A., Londoño‐Vallejo, A., Capogrossi, M. C., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062522 · Cited by 27

Role of Redox Signaling, Protein Phosphatases and Histone Acetylation in the Inflammatory Cascade in Acute Pancreatitis: Therapeutic Implications

Escobar, J., Pereda, J., Arduini, A., Sandoval, J., Sabater, L., Aparisi, L., Vento, M., López‐Rodas, G., & Sastre, J. (2010) · Inflammation & Allergy - Drug Targets · doi:10.2174/187152810791292773 · Cited by 25

Histone deacetylase 3 indirectly modulates tubulin acetylation

Bacon, T., Seiler, C., Wolny, M., Hughes, R., Watson, P., Schwabe, J. W. R., Grigg, R., & Peckham, M. (2015) · Biochemical Journal · doi:10.1042/bj20150660 · Cited by 25

Evidence for a non-canonical role of HDAC5 in regulation of the cardiac Ncx1 and Bnp genes

Harris, L. G., Wang, S. H., Mani, S. K., Kasiganesan, H., Chou, C. J., & Menick, D. R. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv1496 · Cited by 26

Maternal high fat diet induces early cardiac hypertrophy and alters cardiac metabolism in Sprague Dawley rat offspring

Jong, K. A. D., Barrand, S., Wood‐Bradley, R. J., Almeida, D. L., Czeczor, J. K., Lopaschuk, G. D., Armitage, J. A., & McGee, S. L. (2018) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2018.02.019 · Cited by 26

Novel alkoxyamide-based histone deacetylase inhibitors reverse cisplatin resistance in chemoresistant cancer cells

Asfaha, Y., Schrenk, C., Avelar, L. A. A., Lange, F., Wang, C., Bandolik, J. J., Hamacher, A., Kassack, M. U., & Kurz, T. (2019) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2019.115108 · Cited by 25

Epigenetic Regulation as a Basis for Long-Term Changes in the Nervous System: In Search of Specificity Mechanisms

Borodinova, A. A., & Balaban, P. M. (2020) · Biochemistry (Moscow) · doi:10.1134/s0006297920090023 · Cited by 25

Valproic Acid Increases the Stimulatory Effect of Estrogens on Proliferation of Human Endometrial Adenocarcinoma Cells

Graziani, G., Tentori, L., Portarena, I., Vergati, M., & Navarra, P. (2003) · Endocrinology · doi:10.1210/en.2002-0180 · Cited by 23

Histone Deacetylase Inhibitors: Emerging Anticancer Therapeutic Agents?

Kristeleit, R. S., Fong, P. C. C., Aherne, G. W., & Bono, J. S. D. (2005) · Clinical Lung Cancer · doi:10.3816/clc.2005.s.004 · Cited by 24

Histone deacetylase (HDACs) inhibitors: Clinical applications

Shanmukha, K. D., Paluvai, H., Lomada, S. K., Gokara, M., & Kalangi, S. K. (2023) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2023.02.011 · Cited by 26

The Transcriptional Regulator CBP Has Defined Spatial Associations within Interphase Nuclei

McManus, K. J., Stephens, D. A., Adams, N. M., Islam, S. A., Freemont, P. S., & Hendzel, M. J. (2006) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020139 · Cited by 24

Regulation of SMRT corepressor dimerization and composition by MAP kinase phosphorylation

Varlakhanova, N., Hahm, J. B., & Privalsky, M. L. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.10.010 · Cited by 24

Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development

Stengel, K. R., Barnett, K. R., Wang, J., Liu, Q., Hodges, E. C., Hiebert, S. W., & Bhaskara, S. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1701610114 · Cited by 24

Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells

Kasler, H. G., Lee, I. S., Lim, H. W., & Verdin, E. M. (2018) · eLife · doi:10.7554/elife.32109 · Cited by 25

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion

Chang, C., Cheong, M., Chang, G.-D., Tsai, M.-S., & Chen, H. (2013) · Molecular Human Reproduction · doi:10.1093/molehr/gat050 · Cited by 24

Residues K128, 132, and 134 in the Thyroid Hormone Receptor-α Are Essential for Receptor Acetylation and Activity

Sánchez‐Pacheco, A., Martínez-Iglesias, O. A., Méndez‐Pertuz, M., & Aranda, A. (2009) · Endocrinology · doi:10.1210/en.2009-0117 · Cited by 26

Differential effects of histone deacetylase inhibitors on phorbol ester‐ and TGF‐β1 induced murine tissue inhibitor of metalloproteinases‐1 gene expression

Young, D. A., Billingham, O., Sampieri, C. L., Edwards, D. R., & Clark, I. M. (2005) · FEBS Journal · doi:10.1111/j.1742-4658.2005.04622.x · Cited by 24

Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation

Cheung, K. L., Zhao, L., Sharma, R., Ghosh, A., Appiah, M. G., Sun, Y., Jaganathan, A., Hu, Y., Lejeune, A., Xu, F., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2312111121 · Cited by 23

SIK1 promotes ferroptosis resistance in pancreatic cancer via HDAC5-STAT6-SLC7A11 axis

Zhang, H., Ma, T., Wen, X., Jiang, J., Chen, J., Jiang, J., Xie, J., Mo, T., Li, R., Xie, H., et al. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217726 · Cited by 25

Histone Deacetylases As Targets for Antitrypanosomal Drugs

Zuma, A. A., & de Souza, W. (2018) · Future Science OA · doi:10.4155/fsoa-2018-0037 · Cited by 23

Histone Deacetylases and the Nuclear Receptor Corepressor Regulate Lytic-Latent Switch Gene 50 in Murine Gammaherpesvirus 68-Infected Macrophages

Goodwin, M., Molleston, J. M., Canny, S., Hassan, M. A. E., Willert, E. K., Bremner, R., & Virgin, H. W. (2010) · Journal of Virology · doi:10.1128/jvi.00396-10 · Cited by 23

A Substrate-Independent TR-FRET Histone Deacetylase Inhibitor Assay

Marks, B. D., Fakhoury, S. A., Frazee, W. J., Eliason, H. C., & Riddle, S. M. (2011) · SLAS DISCOVERY · doi:10.1177/1087057111422102 · Cited by 23

Histone Acetylation and Deacetylation

Fass, D. M., Kemp, M. M., Schroeder, F. A., Wagner, F. F., Wang, Q., & Holson, E. B. (2012) · Wiley-VCH eBooks · doi:10.1002/3527600906.mcb.201100036 · Cited by 23

HDAC superfamily promoters acetylation is differentially regulated by modafinil and methamphetamine in the mouse medial prefrontal cortex

González, B., Bernardi, A., Torres, O. V., Jayanthi, S., Gomez, N. V., Sosa, M. H., García‐Rill, E., Urbano, F. J., Cadet, J. L., & Bisagno, V. (2019) · Addiction Biology · doi:10.1111/adb.12737 · Cited by 22

E-Cadherin-Deficient Epithelial Cells Are Sensitive to HDAC Inhibitors

Decourtye, L., Bougen-Zhukov, N. M., Godwin, T. D., Brew, T. P., Schulpen, E., Black, M. A., & Guilford, P. (2021) · Cancers · doi:10.3390/cancers14010175 · Cited by 23

Evidence that HDAC7 acts as an epigenetic “reader” of AR acetylation through NCoR-HDAC3 dissociation

Zhang, Y., Andrade, R. E., Hanna, A. A., & Pflum, M. K. H. (2022) · Cell chemical biology · doi:10.1016/j.chembiol.2022.05.008 · Cited by 22

Histone deacetylase inhibition and the regulation of cell growth with particular reference to liver pathobiology

Fraczek, J., van Grunsven, L. A., Vinken, M., Sarah, S., Deleu, S., Vanderkerken, K., Vanhaecke, T., & Rogiers, V. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00831.x · Cited by 21

Parathyroid Hormone Regulates Histone Deacetylases in Osteoblasts

Shimizu, E., Selvamurugan, N., Westendorf, J. J., & Partridge, N. C. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1402.037 · Cited by 21

Novel role and regulation of HDAC4 in cocaine‐related behaviors

Penrod, R. D., Carreira, M. B., Taniguchi, M., Kumar, J., Maddox, S. A., & Cowan, C. W. (2017) · Addiction Biology · doi:10.1111/adb.12522 · Cited by 21

Wrestling Rules in Transrepression: As Easy as SUMO-1, -2, -3?

Treuter, E., & Gustafsson, J.-Å. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.01.009 · Cited by 21

Enhancer function regulated by combinations of transcription factors and cofactors

Nakagawa, T., Yoneda, M., Higashi, M., Ohkuma, Y., & Ito, T. (2018) · Genes to Cells · doi:10.1111/gtc.12634 · Cited by 21

Cytoplasmic HDAC4 recovers synaptic function in the 3×Tg mouse model of Alzheimer's disease

Colussi, C., Aceto, G., Ripoli, C., Bertozzi, A., Puma, D. D. L., Paccosi, E., D’Ascenzo, M., & Grassi, C. (2022) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12861 · Cited by 19

Histone Deacetylase Inhibitors as Cognitive Enhancers and Modifiers of Mood and Behavior

Pal, D., Sahu, P., Mishra, A. K., Hagelgans, A., & Sukocheva, O. A. (2022) · Current Drug Targets · doi:10.2174/1389450124666221207090108 · Cited by 19

Transforming ligands into transcriptional regulators: building blocks for bifunctional molecules

Højfeldt, J. W., Dyke, A. R. V., & Mapp, A. K. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15050b · Cited by 20

Reciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3

Lin, G., LaPensee, C. R., Qin, Z. S., & Schwartz, J. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.07.020 · Cited by 20

Histone deacetylase activity modulates exercise-induced skeletal muscle plasticity in zebrafish (Danio rerio)

Simmonds, A. I. M., & Seebacher, F. (2017) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00378.2016 · Cited by 20

Characterization of Histone Deacetylase Expression Within In Vitro and In Vivo Bladder Cancer Model Systems

Buckwalter, J. M., Chan, W. H.-C., Shuman, L., Wildermuth, T., Ellis-Mohl, J., Walter, V., Warrick, J. I., Wu, X., Kaag, M. G., Raman, J. D., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102599 · Cited by 20

Profiling of Substrates for Zinc‐dependent Lysine Deacylase Enzymes: HDAC3 Exhibits Decrotonylase Activity In Vitro

Madsen, A. S., & Olsen, C. A. (2012) · Angewandte Chemie · doi:10.1002/ange.201203754 · Cited by 20

Epigenetic Activation of the Foxa2 Gene Is Required for Maintaining the Potential of Neural Precursor Cells to Differentiate into Dopaminergic Neurons After Expansion

Bang, S.-Y., Kwon, S. H., Yi, S., Yi, S. A., Park, E., Lee, J., Jang, C., You, J. S., Lee, S., & Han, J. (2014) · Stem Cells and Development · doi:10.1089/scd.2014.0218 · Cited by 20

Epigenetics of the failing heart

Marín-García, J., & Akhmedov, A. T. (2015) · Heart Failure Reviews · doi:10.1007/s10741-015-9483-x · Cited by 20

Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice

Gaur, V., Connor, T., Venardos, K. M., Henstridge, D. C., Martin, S. D., Swinton, C., Morrison, S., Aston‐Mourney, K., Gehrig, S. M., van Ewijk, R., et al. (2017) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12896 · Cited by 18

Trichostatin A attenuates ventilation-augmented epithelial-mesenchymal transition in mice with bleomycin-induced acute lung injury by suppressing the Akt pathway

Li, L., Lee, C.-S., Lin, C., Chen, N., Chuang, L., Hung, C., & Liu, Y.-Y. (2017) · PLoS ONE · doi:10.1371/journal.pone.0172571 · Cited by 19

Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7

Desravines, D. C., Martin, I. S., Schneider, R., Mas, P. J., Aleksandrova, N., Jensen, M. R., Blackledge, M. J., & Hart, D. J. (2017) · Scientific Reports · doi:10.1038/s41598-017-03718-5 · Cited by 19

The role of HDAC11 in obesity‐related metabolic disorders: A critical review

Yang, H., Chen, L., Sun, Q., Yao, F., Saeed, M., & Sun, C. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30286 · Cited by 20

Global histone deacetylase enzymatic activity is an independent prognostic marker associated with a shorter overall survival in chronic lymphocytic leukemia patients

Damme, M. V., Crompot, E., Meuleman, N., Mineur, P., Dessars, B., Housni, H. E., Bron, D., Lagneaux, L., & Stamatopoulos, B. (2014) · Epigenetics · doi:10.4161/15592294.2014.969628 · Cited by 17

The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

Guenther, M. G., Barak, O., & Lazar, M. A. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.18.6091-6101.2001 · Cited by 611

Human HDAC7 Histone Deacetylase Activity Is Associated with HDAC3in Vivo

Fischle, W., Dequiedt, F., Fillion, M., Hendzel, M. J., Voelter, W., & Verdin, E. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104935200 · Cited by 232

Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

Hudson, G. M., Watson, P. J., Fairall, L., Jamieson, A. G., & Schwabe, J. W. R. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.661058 · Cited by 58

Mutagenesis Study Reveals the Rim of Catalytic Entry Site of HDAC4 and -5 as the Major Binding Surface of SMRT Corepressor

Kim, G. S., Jung, H.-E., Kim, J., & Lee, Y. C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132680 · Cited by 8

Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4

Park, S., Kim, G. S., Hwang, H.-J., Nam, T.-H., Park, H.-S., Song, J., Jang, T.-H., Lee, Y. C., & Kim, J. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky926 · Cited by 36