The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
The origin of DNA genomes and DNA replication proteins
Abstract
In recent years, it has became clear that most proteins involved in cellular DNA precursor synthesis or DNA replication have been 'invented' more than once, indicating that the transition from RNA to DNA genomes was more complex than previously thought. Several authors have suggested that DNA viruses, which often encode their own version of these proteins, played an important role in this process. The nature of the genome of the last universal cellular ancestor (LUCA) -- that is, RNA or DNA, prokaryotic-like or eukaryotic-like -- remains in dispute. A hyperthermophilic LUCA would have suggested a circular, double-stranded DNA genome; however, recent data favor a mesophilic or moderately thermophilic LUCA.
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“Specifically, the last common ancestor may have had a cell membrane (Jékely 2006;Koga 2011;Lombard et al. 2012;Sojo et al. 2014;Coleman et al. 2019), RNA and phosphodiester-based energy coupling (e.g.Werner and Grohmann 2011), as well as thioester-based intermediary metabolism (Goldford et al. 2017;Weiss et al. 2018), but may not have used a strictly DNA genome (Mushegian and Koonin 1996;Leipe et”
From The Emergence of Life (2019) · cites this paper as Forterre 2002
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Cites
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Interpreting the universal phylogenetic tree
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Common Origin of Four Diverse Families of Large Eukaryotic DNA Viruses
Iyer, L. M., Aravind, L., & Koonin, E. V. (2001) · Journal of Virology · doi:10.1128/jvi.75.23.11720-11734.2001 · Cited by 556
A mechanism for initiating RNA-dependent RNA polymerization
Butcher, S. J., Grimes, J. M., Makeyev, E. V., Bamford, D. H., & Stuart, D. I. (2001) · Nature · doi:10.1038/35065653 · Cited by 496
A Nonhyperthermophilic Common Ancestor to Extant Life Forms
Galtier, N., Tourasse, N., & Gouy, M. (1999) · Science · doi:10.1126/science.283.5399.220 · Cited by 442
Did DNA replication evolve twice independently?
Leipe, D. D., Aravind, L., & Koonin, E. V. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.17.3389 · Cited by 351
The origins and ongoing evolution of viruses
Hendrix, R. W., Lawrence, J. G., Hatfull, G. F., & Casjens, S. (2000) · Trends in Microbiology · doi:10.1016/s0966-842x(00)01863-1 · Cited by 349
An Alternative Flavin-Dependent Mechanism for Thymidylate Synthesis
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Evolutionary history and higher order classification of AAA+ ATPases
Iyer, L. M., Leipe, D. D., Koonin, E. V., & Aravind, L. (2003) · Journal of Structural Biology · doi:10.1016/j.jsb.2003.10.010 · Cited by 782
Comparative genomics, minimal gene-sets and the last universal common ancestor
Koonin, E. V. (2003) · Nature Reviews Microbiology · doi:10.1038/nrmicro751 · Cited by 661
Diverse Functions of Restriction-Modification Systems in Addition to Cellular Defense
Vasu, K., & Nagaraja, V. (2013) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00044-12 · Cited by 639
Evolutionary genomics of nucleo-cytoplasmic large DNA viruses
Iyer, L. M., Balaji, S., Koonin, E. V., & Aravind, L. (2006) · Virus Research · doi:10.1016/j.virusres.2006.01.009 · Cited by 585
On the origin of genomes and cells within inorganic compartments
Koonin, E. V., & Martin, W. (2005) · Trends in Genetics · doi:10.1016/j.tig.2005.09.006 · Cited by 406
Metadata
- Authors
- Forterre, P.
- Affiliations
- Université Paris-Sud (FR)
- Corresponding author
- Forterre, P
- ORCID
- Forterre, P
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2002-10-01
- Volume
- 5
- Issue
- 5
- Pages
- 525-532
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W1998172162
- Cited by
- 190
- References
- 46
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 4 · 2023: 6 · 2022: 5 · 2021: 5 · 2020: 6 · 2019: 4 · 2018: 9 · 2017: 4 · 2016: 5 · 2015: 10 · 2014: 13 · 2013: 11 · 2012: 11
- FWCI
- 5.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- DNA replication proteins, RNA to DNA transition, DNA viruses, last universal common ancestor
- MeSH terms
- DNA, DNA Replication, Biological Evolution, Models, Genetic, Proteins, RNA, Selection, Genetic
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