Cited by 877Alcohol Consumption and Health EffectsHead and Neck Cancer StudiesEsophageal Cancer Research and Treatment

The DOI matches its Crossref record; 68 of the 70 references it cites were found in a registry or an index.

Alcohol and cancer

Boffetta, Paolo, Hashibe, Mia·2006·The Lancet Oncology

DOI 10.1016/s1470-2045(06)70577-0

Open this paper in CoChat — free account

Abstract

A causal association has been established between alcohol consumption and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colon, rectum, and, in women, breast; an association is suspected for cancers of the pancreas and lung. Evidence suggests that the effect of alcohol is modulated by polymorphisms in genes encoding enzymes for ethanol metabolism (eg, alcohol dehydrogenases, aldehyde dehydrogenases, and cytochrome P450 2E1), folate metabolism, and DNA repair. The mechanisms by which alcohol consumption exerts its carcinogenic effect have not been defined fully, although plausible events include: a genotoxic effect of acetaldehyde, the main metabolite of ethanol; increased oestrogen concentration, which is important for breast carcinogenesis; a role as solvent for tobacco carcinogens; production of reactive oxygen species and nitrogen species; and changes in folate metabolism. Alcohol consumption is increasing in many countries and is an important cause of cancer worldwide.

Integrity signals

Registry

Crossref · 10.1016/s1470-2045(06)70577-0

Cites

68 of 68 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Comparative quantification of health risks : global and regional burden of disease attributable to selected major risk factors
Ezzati, M., López, A. D., Rodgers, A., & Murray, C. J. L. (2004) · Cited by 3,319
Alcohol, tobacco and breast cancer – collaborative reanalysis of individual data from 53 epidemiological studies, including 58 515 women with breast cancer and 95 067 women without the disease
Collaborative Group on Hormonal Factors in Breast Cancer (2002) · British Journal of Cancer · doi:10.1038/sj.bjc.6600596 · Cited by 1,135
A meta-analysis of alcohol consumption and the risk of 15 diseases
Corrao, G. (2004) · Preventive Medicine · doi:10.1016/j.ypmed.2003.11.027 · Cited by 1,077
Alcohol and Breast Cancer in Women
Smith‐Warner, S. A., Spiegelman, D. L., Yaun, S., van den Brandt, P. A., Folsom, A. R., Goldbohm, R. A., Graham, S., Holmberg, L., Howe, G. R., Marshall, J. R., et al. (1998) · JAMA · doi:10.1001/jama.279.7.535 · Cited by 945
Alcohol Consumption and Risk of Stroke
Reynolds, K., Lewis, B. L., Nolen, J. D. L., Kinney, G. L., Sathya, B., & He, J. (2003) · JAMA · doi:10.1001/jama.289.5.579 · Cited by 927
Alcohol and coronary heart disease: a meta-analysis.
Corrao, G., Rubbiati, L., Bagnardi, V., Zambon, A., & Poikolainen, K. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.951015056.x · Cited by 875
Comorbidity of substance use disorders with mood and anxiety disorders
Merikangas, K. R., Mehta, R. L., Molnar, B. E., Walters, E. E., Swendsen, J. D., Aguilar‐Gaxiola, S., Bijl, R. V., Borges, G. L. G., Caraveo-Anduaga, J. J., DeWit, D. J., et al. (1998) · Addictive Behaviors · doi:10.1016/s0306-4603(98)00076-8 · Cited by 747
A meta-analysis of alcohol drinking and cancer risk
Bagnardi, V., Blangiardo, M., Vecchia, C. L., & Corrao, G. (2001) · British Journal of Cancer · doi:10.1054/bjoc.2001.2140 · Cited by 596
Characteristics of binge drinkers in Europe
Kuntsche, E. N., Rehm, J. T., & Gmel, G. E. (2003) · Social Science & Medicine · doi:10.1016/j.socscimed.2003.10.009 · Cited by 580
Alcohol and Breast Cancer
Singletary, K. W., & Gapstur, S. M. (2001) · JAMA · doi:10.1001/jama.286.17.2143 · Cited by 516

Show all 70 references

Research works printed but not linked: 1

Singletary, 2001, Alcohol and breast cancer: review of epidemiologic and experimental evidence and potential mechanisms, JAMA, 286, 2143, 10.1001/jama.286.17.2143 · DOI

Sorted by citations

Items 401–500 of 877

Preventable incidence of carcinoma associated with adiposity, alcohol and physical inactivity according to smoking status in the United States
Song, M., & Giovannucci, E. L. (2019) · International Journal of Cancer · doi:10.1002/ijc.32602 · Cited by 17
Factors Associated With a Prolonged Diagnosis‐to‐Treatment Interval in Laryngeal Squamous Cell Carcinoma
Shaikh, N., Morrow, V. R., Stokes, C. M., Chung, J., Fancy, T., Turner, M., & Stokes, W. A. (2022) · Otolaryngology · doi:10.1177/01945998221090115 · Cited by 17
Lack of association of ADH1C genotype with breast cancer susceptibility in Caucasian population: A pooled analysis of case–control studies
Wang, L., Zhang, Y., Ding, D., He, X., & Zhu, Z. (2012) · The Breast · doi:10.1016/j.breast.2012.01.007 · Cited by 17
New Insights into the High-Density Lipoprotein Dilemma
Pownall, H. J., & Gotto, A. M. (2015) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2015.11.004 · Cited by 18
Alcohol‐attributable cancer deaths under 80 years of age in New Zealand
CONNOR, J. L., Kydd, R. M., Maclennan, B., Shield, K. D., & Rehm, J. T. (2016) · Drug and Alcohol Review · doi:10.1111/dar.12443 · Cited by 17
Cancer Risk Factors Among Adults with Serious Mental Illness
Muirhead, L. (2014) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2013.10.028 · Cited by 18
A national study of alcohol consumption patterns among population-based U.S. cancer survivors compared with cancer-free individuals
Lyu, J., Kaur, M., Dibble, K. E., & Connor, A. E. (2022) · Cancer Epidemiology · doi:10.1016/j.canep.2022.102101 · Cited by 16
Association between alcohol and urolithiasis: a mendelian randomization study
Shi-jian, Y., Tan, W., Wei, B., Gu, C., Li, S., & Wang, S. (2023) · Urolithiasis · doi:10.1007/s00240-023-01472-0 · Cited by 17
Effect of Diet and Oxidative Stress in the Pathogenesis of Lymphoproliferative Disorders
Cancemi, G., Cicero, N., Allegra, A., & Gangemi, S. (2023) · Antioxidants · doi:10.3390/antiox12091674 · Cited by 16
Alcohol dehydrogenase-1B Arg47His polymorphism is associated with head and neck cancer risk in Asian: a meta-analysis
Zhang, Y., Gu, N., Miao, L., Yuan, H., Wang, R., & Jiang, H. (2014) · Tumor Biology · doi:10.1007/s13277-014-2727-x · Cited by 16
Life style factors, tumor cell plasticity and cancer stem cells
Chiodi, I., & Mondello, C. (2020) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2020.108308 · Cited by 17
Associations between nutritional factors and KRAS mutations in colorectal cancer: a systematic review
Asri, A. E., Zarrouq, B., Kinany, K. E., Bouguenouch, L., Ouldim, K., & Rhazi, K. E. (2020) · BMC Cancer · doi:10.1186/s12885-020-07189-2 · Cited by 16
Alcohol and tobacco consumption: What is the role of economic security?
Bentley, R., Baker, E., Martino, E., Li, Y., & Mason, K. (2021) · Addiction · doi:10.1111/add.15400 · Cited by 16
Associations of alcohol use disorders with esophageal and gastric cancers: a population-based study in Sweden
Ji, J., Sundquist, J., & Sundquist, K. (2016) · European Journal of Cancer Prevention · doi:10.1097/cej.0000000000000227 · Cited by 16
Association between single nucleotide polymorphisms in the antioxidant genes CAT, GR and SOD1, erythrocyte enzyme activities, dietary and life style factors and breast cancer risk in a Danish, prospective cohort study
Kopp, T. I., Vogel, U. B., Dragsted, L. O., Tjønneland, A. M., & Ravn‐Haren, G. (2017) · Oncotarget · doi:10.18632/oncotarget.18062 · Cited by 18
Effects of Alcohol Consumption on the Allergen‐Specific Immune Response in Mice
Linneberg, A. R., Roursgaard, M., Hersoug, L., & Larsen, S. T. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00644.x · Cited by 16
A concise review towards defining the exposome of oesophageal cancer in sub-Saharan Africa
Lipenga, T., Matumba, L., Vidal, A., Herceg, Z., McCormack, V., Saeger, S. D., & Boevre, M. D. (2021) · Environment International · doi:10.1016/j.envint.2021.106880 · Cited by 15
Obesity Is Positively Associated and Alcohol Intake Is Negatively Associated with Nephrolithiasis
Kim, S. Y., Yoo, D. M., Bang, W. J., & Choi, H. G. (2022) · Nutrients · doi:10.3390/nu14194122 · Cited by 15
Factors associated with public awareness of the relationship between alcohol use and breast cancer risk
Doyle, A., O’Dwyer, C., Mongan, D., Millar, S., & Galvin, B. (2023) · BMC Public Health · doi:10.1186/s12889-023-15455-8 · Cited by 14
The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study
Andersen, V. C., Agerstjerne, L., Jensen, D., Østergaard, M., Sæbø, M., Hamfjord, J., Kure, E. H., & Vogel, U. B. (2009) · BMC Medical Genetics · doi:10.1186/1471-2350-10-18 · Cited by 15
Role of OGG1 Ser326Cys polymorphism and 8-oxoguanine DNA damage in risk assessment of squamous cell carcinoma of head and neck in north Indian population
Kumar, A. T., Pant, M. C., Singh, H. S., & Khandelwal, S. (2011) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2011.09.015 · Cited by 17
Heavy Alcohol Use and Premature Death from Hepatocellular Carcinoma in the United States, 1999–2006
Dong, C., Yoon, Y., Chen, C. M., & Yi, H. (2011) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2011.72.892 · Cited by 15
Maps and atlases of cancer mortality: a review of a useful tool to trigger new questions
d’Onofrio, A., Mazzetta, C., Robertson, C., Smans, M., Boyle, P., & Boniol, M. (2016) · ecancermedicalscience · doi:10.3332/ecancer.2016.670 · Cited by 15
Mechanisms underlying the effects of nutrition, adiposity and physical activity on colorectal cancer risk
Malcomson, F. C. (2018) · Nutrition Bulletin · doi:10.1111/nbu.12359 · Cited by 16
A roadmap of six different pathways to improve survival in laryngeal cancer patients
Bradley, P. J., Piazza, C., & Paderno, A. (2020) · Current Opinion in Otolaryngology & Head & Neck Surgery · doi:10.1097/moo.0000000000000684 · Cited by 14
Controversial risk factors for cholangiocarcinoma
Baidoun, F., Sarmini, M. T., Merjaneh, Z., & Moustafa, M. A. (2021) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000002313 · Cited by 15
Frequent low dose alcohol intake increases gastric cancer risk: the Health Examinees-Gem (HEXA-G) study
Lee, H.-W., Huang, D., Shin, W., la Torre, K. D., Song, M., Shin, A., Lee, J., & Kang, D. (2022) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2021.0642 · Cited by 15
Thiophene bridged aldehydes (TBAs) image ALDH activity in cells via modulation of intramolecular charge transfer
Maity, S., Sadlowski, C. M., Lin, J.-M. G., Chen, C., Peng, L., Lee, E.-S., Vegesna, G. K., Lee, C., Kim, S., Mochly‐Rosen, D., et al. (2017) · Chemical Science · doi:10.1039/c7sc03017g · Cited by 15
Alcohol intake aggravates adipose browning and muscle atrophy in cancer-associated cachexia
Wang, B., Zhang, F., Zhang, H., Wang, Z., Ma, Y., Zhu, M. J., & Du, ‬. (2017) · Oncotarget · doi:10.18632/oncotarget.22243 · Cited by 15
Association of ADH1B Arg47His polymorphism with the risk of cancer: a meta-analysis
Tan, B., & Ning, N. (2019) · Bioscience Reports · doi:10.1042/bsr20181915 · Cited by 15
Upregulation of β‐Catenin Levels in Superior Frontal Cortex of Chronic Alcoholics
Alhousseini, A., Sivanandam, T. M., Bradbury, E. L., Tannenberg, R. K., Dodd, P. R., & Gu, Q. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00670.x · Cited by 15
Alcohol consumption and distinct molecular pathways to colorectal cancer
Bongaerts, B. W. C., de Goeij, A. F. P. M., de Vogel, S., van den Brandt, P. A., Goldbohm, R. A., & Weijenberg, M. P. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507381336 · Cited by 15
Cancer Mortality in Italy, 1970–2002
Malvezzi, M., Bosetti, C., Negri, E., Vecchia, C. L., & Decarli, A. (2008) · Tumori Journal · doi:10.1177/030089160809400502 · Cited by 15
Association of Alcohol Drinking Patterns with Metabolic Syndrome and Its Components in Korean Adults: The Korea National Health and Nutrition Examination Survey 2016–2018
Lee, S. W., & Jang, S. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18126433 · Cited by 14
Joint association of alcohol consumption and adiposity with alcohol- and obesity-related cancer in a population sample of 399,575 UK adults
Eroglu, E. I., Huang, B., Sarich, P., Nassar, N., & Stamatakis, E. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522003464 · Cited by 14
Spatial investigation of the links between aflatoxins legislation, climate, and liver cancer at the global scale
Tueller, G., Kerry, R., & Young, S. G. (2023) · Spatial and Spatio-temporal Epidemiology · doi:10.1016/j.sste.2023.100592 · Cited by 14
Alcohol consumption and cancer incidence in women: interaction with smoking, body mass index and menopausal hormone therapy
Floud, S., Hermon, C., Simpson, R. F., & REEVES, G. K. (2023) · BMC Cancer · doi:10.1186/s12885-023-11184-8 · Cited by 15
A State-of-the-Science Review of Alcoholic Beverages and Polycyclic Aromatic Hydrocarbons
King, L., Aplin, R., Gill, C. G., & Naimi, T. S. (2024) · Environmental Health Perspectives · doi:10.1289/ehp13506 · Cited by 14
Alcohol consumption, alcohol dehydrogenase 1C (ADH1C) genotype, and risk of colorectal cancer in the Netherlands Cohort Study on diet and cancer
Bongaerts, B. W. C., de Goeij, A. F. P. M., Wouters, K. A. D., van Engeland, M., Gottschalk, R. W. H., van Schooten, F., Goldbohm, R. A., van den Brandt, P. A., & Weijenberg, M. P. (2010) · Alcohol · doi:10.1016/j.alcohol.2010.10.003 · Cited by 14
Social disparities, health risk behaviors, and cancer
Rametta, S., Grosso, G., Galvano, F., Mistretta, A., Marventano, S., Nolfo, F., Buscemi, S., Gangi, S., Basile, F., & Biondi, A. (2013) · BMC Surgery · doi:10.1186/1471-2482-13-s2-s17 · Cited by 14
Examining the Association Between Alcohol Consumption and Health Conditions in Community Dwelling Older Adults
Laberge, S., Bigelow, P., Lagarde, E., & Crizzle, A. M. (2020) · Journal of Community Health · doi:10.1007/s10900-020-00842-8 · Cited by 14
Statins and the risks of decompensated liver cirrhosis and hepatocellular carcinoma determined in patients with alcohol use disorder
Chiu, W., Shan, J., Yang, Y., Chen, V. C., & Chen, P. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.109096 · Cited by 14
Embedded Transdermal Alcohol Detection via a Finger Using SnO2 Gas Sensors
Annanouch, F. E., Martini, V., Fiorido, T., Lawson, B., Aguir, K., & Bendahan, M. (2021) · Sensors · doi:10.3390/s21206852 · Cited by 14
Increasing trends in kidney cancer over the last 2 decades in Saudi Arabia
Alkhateeb, S. S., Alkhateeb, J. M., & Alrashidi, E. A. (2015) · Saudi Medical Journal · doi:10.15537/smj.2015.6.10841 · Cited by 14
Alcohol consumption and lung cancer risk in never smokers
García-Lavandeira, J. A., Ruano‐Raviña, A., & Barros-Dios, J. M. (2016) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2016.03.017 · Cited by 14
Alcohol-Related Disease
Finnell, J. T., & McMicken, D. B. (2010) · Elsevier eBooks · doi:10.1016/b978-0-323-05472-0.00183-3 · Cited by 14
Effect of alcohol and its metabolites in lung cancer: CAPUA study
Álvarez-Avellón, S. M., Fernández‐Somoano, A., Navarrete‐Muñoz, E. M., Vioqué, J., & Tardón, A. (2017) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2016.12.072 · Cited by 14
SEX COMPOSITION OF THE WORKPLACE AND MORTALITY RISK
Barclay, K. (2012) · Journal of Biosocial Science · doi:10.1017/s002193201200079x · Cited by 14
Efecto del alcohol y sus metabolitos en el cáncer de pulmón: estudio CAPUA
Álvarez-Avellón, S. M., Fernández‐Somoano, A., Navarrete‐Muñoz, E. M., Vioqué, J., & Tardón, A. (2017) · Medicina Clínica · doi:10.1016/j.medcli.2016.12.033 · Cited by 14
Capacity of a Microbial Synbiotic To Rescue the In Vitro Metabolic Activity of the Gut Microbiome following Perturbation with Alcohol or Antibiotics
Tierney, B. T., den Abbeele, P. V., Al‐Ghalith, G. A., Verstrepen, L., Ghyselinck, J., Calatayud, M., Marzorati, M., Abdel-Gadir, A., Daisley, B. A., Reid, G., et al. (2023) · Applied and Environmental Microbiology · doi:10.1128/aem.01880-22 · Cited by 14
Unpacking assertions made by the alcohol industry and how they make them: An analysis of submissions into Australia's National Alcohol Strategy
Miller, M., Livingston, M., Maganja, D., & Wright, C. C. J. (2023) · Drug and Alcohol Review · doi:10.1111/dar.13682 · Cited by 13
Tacrolimus Drug Exposure Level and Smoking Are Modifiable Risk Factors for Early De Novo Malignancy After Liver Transplantation for Alcohol-Related Liver Disease
Vanlerberghe, B. T. K., van Malenstein, H., Sainz‐Barriga, M., Jochmans, I., Cassiman, D. M., Monbaliu, D. R. L., der Merwe, V., Pirenne, J., Nevens, F., & Verbeek, J. (2024) · Transplant International · doi:10.3389/ti.2024.12055 · Cited by 13
Global, regional, and national burden and trends of air pollution-related neoplasms from 1990 to 2019: An observational trend study from the Global Burden of Disease Study 2019
Ren, F., & Liu, G. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117068 · Cited by 13
Polimorfismo do gene metilenotetra-hidrofolato redutase (MTHFR) e o risco de carcinoma espinocelular de cabeça e pescoço
Rodrigues, J. O., Galbiatti, A. L. S., Ruiz, M. T., Raposo, L. S., Maníglia, J. V., Pavarino, É. C., & Goloni‐Bertollo, E. M. (2010) · Brazilian Journal of Otorhinolaryngology · doi:10.1590/s1808-86942010000600017 · Cited by 13
Detection of an alcohol-associated cancer marker by single-molecule quantum sequencing
Komoto, Y., Ohshiro, T., & Taniguchi, M. (2020) · Chemical Communications · doi:10.1039/d0cc05914e · Cited by 13
Associations between hepatitis B virus infection and risk of colorectal Cancer: a population-based prospective study
Liu, T., Li, W., Zhang, Y., Siyin, S. T., Zhang, Q., Song, M., Zhang, K., Liu, S., & Shi, H. (2021) · BMC Cancer · doi:10.1186/s12885-021-08846-w · Cited by 13
Helping Individuals to Understand Synergistic Risks: An Assessment of Message Contents Depicting Mechanistic and Probabilistic Concepts
Dawson, I. G. J., JOHNSON, J. E. V., & Luke, M. A. (2012) · Risk Analysis · doi:10.1111/j.1539-6924.2012.01878.x · Cited by 13
Coffee and alcohol consumption and bladder cancer
Pelucchi, C., Tavani, A., & Vecchia, C. L. (2008) · Scandinavian Journal of Urology and Nephrology · doi:10.1080/03008880802237090 · Cited by 12
DNA repair mutant pso2 of Saccharomyces cerevisiae is sensitive to intracellular acetaldehyde accumulated by disulfiram-mediated inhibition of acetaldehyde dehydrogenase
Brendel, M., Marisco, G., Ganda, I. S., Wolter, R., & Pungartnik, C. (2010) · Genetics and Molecular Research · doi:10.4238/vol9-1gmr695 · Cited by 13
Alcohol consumption and risk of myelodysplastic syndromes: A meta-analysis of epidemiological studies
Jin, J., Yu, M., Hu, C., Li, Y., Xie, L., Chen, F., Zhuang, Z., & Tong, H. (2014) · Molecular and Clinical Oncology · doi:10.3892/mco.2014.376 · Cited by 13
Impact of multiple Alcohol Dehydrogenase gene polymorphisms on risk of laryngeal, esophageal, gastric and colorectal cancers in Chinese Han population.
An, J., Zhao, J., Zhang, X., Ding, R., Geng, T., Feng, T., & Jin, T. (2015) · Europe PMC (PubMed Central) · Cited by 13
Is there an association between trends in alcohol consumption and cancer mortality? Findings from a multicountry analysis
Schwartz, N. S., Nishri, D., Cheong, S. C., Giesbrecht, N., & Klein-Geltink, J. (2017) · European Journal of Cancer Prevention · doi:10.1097/cej.0000000000000403 · Cited by 13
Oral Mucosal Malignancies
Farah, C. S., Kujan, O., Prime, S. S., & Zain, R. B. (2019) · Springer eBooks · doi:10.1007/978-3-319-72303-7_21 · Cited by 14
Detection of laryngeal carcinoma in the U.S. elderly population with gastroesophageal reflux disease
Riley, C. A., Marino, M. J., Hsieh, M., Wu, E. L., Wu, X., & McCoul, E. D. (2019) · Head & Neck · doi:10.1002/hed.25600 · Cited by 13
The impact of handling missing data on alcohol consumption estimates in the UK women cohort study
Nur, U., Longford, N. T., Cade, J. E., & Greenwood, D. C. (2009) · European Journal of Epidemiology · doi:10.1007/s10654-009-9384-1 · Cited by 13
Effects to exposure of tobacco smoke and alcohol on the tongue and pharynx of rats
Martins, R. H. G., Madeira, S. L., Fabro, A. T., Rocha, N. S., Semenzati, G. D. O., & Alves, K. F. (2012) · Inhalation Toxicology · doi:10.3109/08958378.2011.649190 · Cited by 13
Radiation‐induced sarcoma of head and neck: Clinical characteristics and molecular signatures
Liao, Y., Hsu, C., Leu, C., Lai, S., Huang, Y.-L. O., Hsieh, M., Chen, T., Chen, C., Wang, C., Yang, T., et al. (2022) · Head & Neck · doi:10.1002/hed.27279 · Cited by 14
Curcumin attenuates smoking and drinking activated NF-κB/IL-6 inflammatory signaling axis in cervical cancer
Kashyap, V. K., Nagesh, P. K. B., Singh, A. K., Massey, A. E., Peasah-Darkwah, G., George, A., Khan, S., Hafeez, B. B., Zafar, N., Kumar, S., et al. (2024) · Cancer Cell International · doi:10.1186/s12935-024-03513-z · Cited by 12
Consumption of Red Versus White Wine and Cancer Risk: A Meta-Analysis of Observational Studies
Lim, R. K., Rhee, J., Hoang, M., Qureshi, A. A., & Cho, E. (2025) · Nutrients · doi:10.3390/nu17030534 · Cited by 12
Association of Nonsteroidal Anti-Inflammatory Drugs with Colorectal Cancer by Subgroups in the VITamins and Lifestyle (VITAL) Study
Wang, X., Peters, U., Potter, J. D., & White, E. (2015) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-1253 · Cited by 12
Assessment of Natural Killer (NK) and NKT Cells in Murine Spleens and Livers
Shey, M. R., & Ballas, Z. K. (2008) · Methods in molecular biology · doi:10.1007/978-1-59745-242-7_18 · Cited by 12
Consumption of alcoholic beverages in adolescence and adulthood and risk of testicular germ cell tumor
Biggs, M. L., Doody, D. R., Trabert, B. L., Starr, J. R., Chen, C., & Schwartz, S. M. (2016) · International Journal of Cancer · doi:10.1002/ijc.30368 · Cited by 12
Polymorphism study of nine SNPs associated with subjective response to alcohol in Chinese Han, Hui, Tibetan, Mongolian and Uygur populations
Wei, Q., Ye, Y., Chen, F., Li, J., Wu, H., Fu, Y., Yan, Y., & Liao, L. (2018) · Forensic Sciences Research · doi:10.1080/20961790.2018.1468538 · Cited by 12
Alcohol consumption is associated with the risk of developing colorectal neoplasia: Propensity score matching analysis
Yang, Y. J., Bang, C. S., Choi, J. H., Lee, J. J., Shin, S. P., Suk, K. T., Baik, G. H., & Kim, D. J. (2019) · Scientific Reports · doi:10.1038/s41598-019-44719-w · Cited by 12
Global Epidemiology of Gastrointestinal Cancers
Dızdar, Ö., & Kılıçkap, S. (2019) · Springer eBooks · doi:10.1007/978-3-030-18890-0_1 · Cited by 14
Chronic ethanol intake promotes double gluthatione S‐transferase/transforming growth factor‐α‐positive hepatocellular lesions in male Wistar rats
Pires, P. W., Furtado, K. S., Justulin, L. A., Rodrigues, M. A. M., Felisbino, S. L., & Barbisan, L. F. (2008) · Cancer Science · doi:10.1111/j.1349-7006.2007.00677.x · Cited by 12
Banding carcinogenic risks in developed countries: A procedural basis for qualitative assessment
Stewart, B. W. (2007) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2007.11.007 · Cited by 12
Oxidative Stress and the Intersection of Oncogenic Signaling and Metabolism in Squamous Cell Carcinomas
Choe, J. H., Mazambani, S., Kim, T. H., & Kim, J. (2021) · Cells · doi:10.3390/cells10030606 · Cited by 14
Environmental causes of cancer
Wadgaonkar, P. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13209-4.00017-9 · Cited by 16
Underappreciated role of binge drinking in the risk of lung cancer
Waszkiewicz, N., Szajda, S. D., Konarzewska, B., Szulc, A., Kępka, A., & Zwierz, K. (2009) · European Journal of Public Health · doi:10.1093/eurpub/ckp094 · Cited by 11
Increasing incidence in liver cancer in Canada, 1972-2006: Age-period-cohort analysis.
Jiang, X., Pan, S. Y., de Groh, M., Liu, S., & MORRISON, H. I. (2011) · PubMed Central · doi:10.3978/j.issn.2078-6891.2011.024 · Cited by 11
Alcohol's contribution to cancer is underestimated for exactly the same reason that its contribution to cardioprotection is overestimated
Stockwell, T. R., & Zhao, J. (2016) · Addiction · doi:10.1111/add.13627 · Cited by 11
Incidence of Cancer in Shenzhen, Guangdong Province during 2001–2015: A Retrospective Population-Based Study
Xu, Z., Zhou, H., Lei, L., Li, H., Yu, W., Fu, Z., Wu, N., Peng, J., & Yin, P. (2017) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph14101137 · Cited by 11
Estimation of Breast Cancer Incident Cases and Medical Care Costs Attributable to Alcohol Consumption Among Insured Women Aged <45 Years in the U.S.
Ekwueme, D. U., Allaire, B. T., Parish, W. J., Thomas, C. C., Poehler, D. C., Guy, G. P., Aldridge, A., Lahoti, S. R., Fairley, T. L., & Trogdon, J. G. (2017) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2017.05.023 · Cited by 11
Increase of hypophyseal hormone levels in male head and neck cancer patients
Remenár, É., Számel, I., Budai, B., Vincze, B., Gaudi, I., Gundy, S., & Kásler, M. (2007) · Pathology & Oncology Research · doi:10.1007/bf02940314 · Cited by 11
Drinking is Different! Examining the Role of Locus of Control for Alcohol ConsumptionPreprint
Caliendo, M., & Hennecke, J. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3608522 · Cited by 11
Association of KMT2C Genetic Variants with the Clinicopathologic Development of Oral Cancer
Shieu, M., Ho, H., Lin, S., Lo, Y., Lin, C., Chuang, Y., Hsieh, M., & Chen, M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19073974 · Cited by 10
Plasma MicroRNA Signature of Alcohol Consumption: The Rotterdam Study
Karabegović, I., Abozaid, Y. J., Maas, S. C. E., Labrecque, J. A., Bos, D., de Knegt, R. J., Ikram, M. A., Voortman, T., & Ghanbari, M. (2022) · Journal of Nutrition · doi:10.1093/jn/nxac216 · Cited by 10
Health Behavior and Cancer Prevention among Adults with Li-Fraumeni Syndrome and Relatives in Germany—A Cohort Description
Nees, J., Kiermeier, S., Strüwe, F. J., Keymling, M., Maatouk, I., Kratz, C. P., & Schott, S. (2022) · Current Oncology · doi:10.3390/curroncol29100614 · Cited by 11
Disordered alcohol and substance use in Irish farmers: A cross‐sectional survey
O’Connor, S., Malone, S. M., Firnhaber, J., O’Shaughnessy, B. R., McNamara, J. G., & O’Hagan, A. D. (2023) · The Journal of Rural Health · doi:10.1111/jrh.12783 · Cited by 10
Cancer cases attributable to alcohol consumption in Brazil
Thuler, L. C. S., de Menezes, R. F., & Bergmann, A. K. (2016) · Alcohol · doi:10.1016/j.alcohol.2016.05.004 · Cited by 10
Light Alcohol Drinking and the Risk of Cancer Development: A Controversial Relationship
Caprio, G. G., Picascia, D., Dallio, M., Vitiello, P. P., Giunta, E. F., Falco, V. D., Abenavoli, L., Procopio, A. C., Famiglietti, V., Martinelli, E., et al. (2020) · Reviews on Recent Clinical Trials · doi:10.2174/1574887115666200628143015 · Cited by 10
Smoking-, Alcohol-, and Age-Related Alterations of Blood Monocyte Subsets and Circulating CD4/CD8 T Cells in Head and Neck Cancer
Idel, C., Loyal, K., Rades, D., Hakim, S. G., Schumacher, U., Bruchhage, K., & Pries, R. (2022) · Biology · doi:10.3390/biology11050658 · Cited by 11
Alcohol Policy in Canada: Reflections on the Role of the Alcohol Industry
Giesbrecht, N. (2006) · Nordic Studies on Alcohol and Drugs · doi:10.1177/145507250602300606 · Cited by 10
Does adequate physical activity attenuate the associations of alcohol and alcohol‐related cancer mortality? A pooled study of 54 686 British adults
Feng, Y., Powell, L., Vassallo, A. J., Hamer, M., & Stamatakis, E. (2020) · International Journal of Cancer · doi:10.1002/ijc.33052 · Cited by 11
Lifetime history of alcohol consumption and K‐ras mutations in pancreatic ductal adenocarcinoma
Crous‐Bou, M., Porta, M. S., López‐Jiménez, T., Jariod, M., Malats, N., Morales, E., Guarner, L., Rifà, J., Carrato, A., Real, F. X., et al. (2009) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20483 · Cited by 10
Metachronous second primary neoplasia in oropharyngeal cancer patients: Impact of tumor HPV status. A GETTEC multicentric study
Milliet, F., Bozec, A., Schiappa, R., Viotti, J., Modesto, A., Dassonville, O., Poissonnet, G., Guelfucci, B., Bizeau, A., Vergèz, S., et al. (2021) · Oral Oncology · doi:10.1016/j.oraloncology.2021.105503 · Cited by 9
A Discourse of Deviance: Blame, Shame, Stigma and the Social Construction of Head and Neck Cancer
Thamm, C., McCarthy, A. L., & Yates, P. M. (2023) · Qualitative Health Research · doi:10.1177/10497323231213819 · Cited by 9
DNA modifications: Biomarkers for the exposome?
Möller, C., Virzi, J., Chang, Y.-J., Keidel, A., Chao, M., Hu, C., & Cooke, M. S. (2024) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2024.104449 · Cited by 9
Global, regional and national burden and trends of larynx cancer among adults aged 55 and older from 1990 to 2021: results from the global burden of disease study 2021
Liao, L., Wang, H., Cui, W., Zhang, Q., He, X., Wang, L., Xiong, Y., Jiang, L., & Xie, Y. (2025) · BMC Public Health · doi:10.1186/s12889-025-21993-0 · Cited by 9

Authors: Boffetta, P., & Hashibe, M.
Affiliations: Centre international de recherche sur le cancer (FR)
Corresponding author: Boffetta, Paolo
ORCID: Boffetta, Paolo
Hashibe, Mia
Venue: The Lancet Oncology
Publisher: Elsevier BV
Published: 2006-02
Volume: 7
Issue: 2
Pages: 149-156
ISSN: 1470-2045 (ISSN-L)
DOI: 10.1016/s1470-2045(06)70577-0
OpenAlex: W4241577617
Cited by: 877
References: 70
Citations by year: 2026: 19 · 2025: 45 · 2024: 36 · 2023: 47 · 2022: 66 · 2021: 58 · 2020: 54 · 2019: 37 · 2018: 44 · 2017: 48 · 2016: 45 · 2015: 51 · 2014: 42 · 2013: 43 · 2012: 52
FWCI: 5.40
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: The Lancet Oncology (publishedVersion)
PubMed (publishedVersion)
Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
Topics: Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
Health Sciences › Medicine › Surgery › Esophageal Cancer Research and Treatment
Keywords: alcohol consumption, alcohol-related cancer, oral cancer, pharyngeal cancer, laryngeal cancer, esophageal cancer, liver cancer, colorectal cancer, breast cancer, pancreatic cancer, lung cancer, alcohol metabolism, alcohol dehydrogenase, aldehyde dehydrogenase, CYP2E1, folate metabolism, DNA repair, acetaldehyde, genotoxicity, estrogen, tobacco carcinogens, reactive oxygen species, carcinogenesis mechanisms
MeSH terms: Alcohol Drinking, Ethanol, Female, Humans, Male, Neoplasms, Genetic Predisposition to Disease

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Alcohol and cancer

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks