IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

Springer, T. A. (1994) · Cell · doi:10.1016/0092-8674(94)90337-9 · Cited by 7,009

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

Fadok, V. A., Bratton, D. L., Konowal, A., Freed, P. W., Westcott, J. Y., & Henson, P. M. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1112 · Cited by 3,166

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.

Xing, Z., Gauldie, J., Cox, G., Baumann, H., Jordana, M., Lei, X.-F., & Achong, M. K. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1368 · Cited by 1,578

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

Savill, J. S., Wyllie, A. H., Henson, J. E., Walport, M. J., Henson, P. M., & Haslett, C. (1989) · Journal of Clinical Investigation · doi:10.1172/jci113970 · Cited by 1,536

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

Taga, T., Hibi, M., Hirata, Y., Yamasaki, K., Yasukawa, K., Matsuda, T., Hirano, T., & Kishimoto, T. (1989) · Cell · doi:10.1016/0092-8674(89)90438-8 · Cited by 1,396

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo

Atreya, R., Mudter, J., Finotto, S., Müllberg, J., Jostock, T., Wirtz, S., Schütz, M., Bartsch, B., Holtmann, M., Becker, C., et al. (2000) · Nature Medicine · doi:10.1038/75068 · Cited by 1,293

Role of IL-6 and Its Soluble Receptor in Induction of Chemokines and Leukocyte Recruitment

Romano, M., Sironi, M., Toniatti, C., Polentarutti, N., Fruscella, P., Ghezzi, P., Faggioni, R., Luini, W., van Hinsbergh, V. W. M., Sozzani, S., et al. (1997) · Immunity · doi:10.1016/s1074-7613(00)80334-9 · Cited by 1,124

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

Hurst, S. M., Wilkinson, T. S., McLoughlin, R. M., Jones, S., Horiuchi, S., Yamamoto, N., Rose-John, S., Fuller, G. M., Topley, N., & Jones, S. A. (2001) · Immunity · doi:10.1016/s1074-7613(01)00151-0 · Cited by 811

Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking

Randolph, G. J., Beaulieu, S., Lebecque, S., Steinman, R. M., & Müller, W. A. (1998) · Science · doi:10.1126/science.282.5388.480 · Cited by 809

Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation

Buckley, C. D., Pilling, D., Lord, J. M., Akbar, A. N., Scheel-Toellner, D., & Salmon, M. (2001) · Trends in Immunology · doi:10.1016/s1471-4906(01)01863-4 · Cited by 796

Positionspapier: Anwendung von Biologika bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem – Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC)

Klimek, L., Förster‐Ruhrmann, U., Becker, S., Chaker, A. M., Strieth, S., Hoffmann, T. K., Dazert, S., Deitmer, T., Olze, H., Glien, A., et al. (2020) · Laryngo-Rhino-Otologie · doi:10.1055/a-1197-0136 · Cited by 34

Characterization of the innate immune response in goats after intrauterine infusion of E. coli using histopathological, cytologic and molecular analyses

Shao, C., Wang, H., Meng, X., Zhu, J.-Q., Wu, Y.-D., & Li, J.-J. (2012) · Theriogenology · doi:10.1016/j.theriogenology.2012.03.005 · Cited by 34

Annotation of Differential Gene Expression in Small Yellow Follicles of a Broiler-Type Strain of Taiwan Country Chickens in Response to Acute Heat Stress

Cheng, C., Tu, W., Wang, S.-H., Tang, P., Chen, C., Chen, H.-H., Lee, Y., Chen, S., & Huang, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143418 · Cited by 34

Thymidine starvation promotes c-di-AMP-dependent inflammation during pathogenic bacterial infection

Tang, Q., Precit, M. R., Thomason, M. K., Blanc, S. F., Ahmed-Qadri, F., McFarland, A. P., Wolter, D. J., Hoffman, L. R., & Woodward, J. J. (2022) · Cell Host & Microbe · doi:10.1016/j.chom.2022.03.028 · Cited by 38

Signaling to Translational Control Pathways: Diversity in Gene Regulation in Inflammatory and Vascular Cells

Lindemann, S. W., Weyrich, A. S., & Zimmerman, G. A. (2005) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2004.10.004 · Cited by 33

Proteomic and Transcriptomic Analyses of Macrophages with an Increased Resistance to Oxidized Low Density Lipoprotein (oxLDL)-induced Cytotoxicity Generated by Chronic Exposure to oxLDL

Conway, J., & Kinter, M. T. (2005) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m500111-mcp200 · Cited by 33

In Silico and In Vivo Experiments Reveal M-CSF Injections Accelerate Regeneration Following Muscle Laceration

Martin, K. S., Kegelman, C. D., Virgilio, K. M., Passipieri, J. A., Christ, G., Blemker, S., & Peirce, S. (2017) · Annals of Biomedical Engineering · doi:10.1007/s10439-016-1707-2 · Cited by 23

Plantamajoside from Plantago asiatica modulates human umbilical vein endothelial cell dysfunction by glyceraldehyde-induced AGEs via MAPK/NF-κB

Son, W.-R., Nam, M., Hong, C., Kim, Y., & Lee, K. (2017) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-017-1570-1 · Cited by 32

Girinimbine from curry leaves promotes gastro protection against ethanol induced peptic ulcers and improves healing via regulation of anti-inflammatory and antioxidant mechanisms

Mohan, S., Hobani, Y. H., Shaheen, E. S., Abou-Elhamd, A. S., Abdelhaleem, A. A., Alhazmi, H. A., & Abdelwahab, S. İ. (2020) · Food & Function · doi:10.1039/d0fo00053a · Cited by 32

Bacterial Translocation – Impact on the Adipocyte Compartment

Kruis, T., Batra, A., & Siegmund, B. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00510 · Cited by 34

Polarized Epithelial Cells Secrete Interleukin 6 Apically in the Bovine Endometrium1

Healy, L. L., Cronin, J., & Sheldon, I. M. (2015) · Biology of Reproduction · doi:10.1095/biolreprod.115.127936 · Cited by 32

Hyaluronidase decreases neutrophils infiltration to the inflammatory site

Fronza, M., Muhr, C., da Silveira, D. S. C., Sorgi, C. A., Rodrigues, S. F., Farsky, S. H. P., Paula‐Silva, F. W. G., Merfort, I., & Faccioli, L. H. (2016) · Inflammation Research · doi:10.1007/s00011-016-0935-0 · Cited by 32

Vibration enhances PGE2, IL‐6, and IL‐8 expression in compressed hPDL cells via cyclooxygenase pathway

Phusuntornsakul, P., Jitpukdeebodintra, S., Pavasant, P., & Leethanakul, C. (2018) · Journal of Periodontology · doi:10.1002/jper.17-0653 · Cited by 32

Cytokines and Inflammatory Response in the Fetus and Neonate

Srinivasan, L., Harris, M. C., & Kilpatrick, L. E. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-35214-7.00128-1 · Cited by 31

Gambogic acid alleviates inflammation and apoptosis and protects the blood-milk barrier in mastitis induced by LPS

Tang, X., Liu, C., Li, T., Lin, C., Hao, Z., Zhang, H., Zhao, G., Chen, Y., Guo, A., & Hu, C. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106697 · Cited by 31

Interleukin-6 (IL-6) deficiency enhances intramembranous osteogenesis following stress fracture in mice

Coates, B. A., McKenzie, J. A., Yoneda, S., & Silva, M. J. (2020) · Bone · doi:10.1016/j.bone.2020.115737 · Cited by 31

An anti‐inflammatory oligopeptide produced by Entamoeba histolytica down‐regulates the expression of pro‐inflammatory chemokines

Utrera‐Barillas, D., Velazquez, J. R., Enciso, J. A., Muñoz-Cruz, S., Rico, G., Curiel‐Quesada, E., Teran, L. M., & Kretschmer, R. R. (2003) · Parasite Immunology · doi:10.1111/j.1365-3024.2003.00657.x · Cited by 31

Changes in chemokines and their receptors in blood during treatment with the TNF inhibitor infliximab in patients with rheumatoid arthritis

Eriksson, C., Rantapää‐Dahlqvist, S., & Sundqvist, K.-G. (2013) · Scandinavian Journal of Rheumatology · doi:10.3109/03009742.2012.754937 · Cited by 31

Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration

Takeda, T., Komiya, Y., Koga, T., Ishida, T., Ishii, Y., Kikuta, Y., Nakaya, M., Kurose, H., Yokomizo, T., Shimizu, T., et al. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.764332 · Cited by 31

Modulation of PPARα Expression and Inflammatory Interleukin-6 Production by Chronic Glucose Increases Monocyte/Endothelial Adhesion

Srinivasan, S., Hatley, M. E., Reilly, K. B., Danziger, E. C., & Hedrick, C. (2004) · Arteriosclerosis, Thrombosis and Vascular Biology · doi:10.1161/01.atv.zhq0504.2260 · Cited by 39

Glycoprotein isolated from Cudrania tricuspidata Bureau inhibits iNO and COX-2 expression through modulation of NF-κB in LPS-stimulated RAW 264.7cells

Joo, H., & Lim, K. (2008) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2008.10.014 · Cited by 31

Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human geneticsPreprint

Jagadeesh, K. A., Dey, K. K., Montoro, D. T., Mohan, R. R., Gazal, S., Engreitz, J., Xavier, R. J., Price, A. L., & Regev, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.03.19.436212 · Cited by 31

COVID-19 Usurps Host Regulatory Networks

Curran, C. S., Rivera, D. R. R., & Kopp, J. B. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01278 · Cited by 31

The Synthetic Myeloperoxidase Inhibitor AZD3241 Ameliorates Dextran Sodium Sulfate Stimulated Experimental Colitis

Ahmad, G., Chami, B., Liu, Y., Schroder, A. L., Gabriel, P. T. S., Gao, A., Fong, G., Wang, X., & Witting, P. K. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.556020 · Cited by 30

Fish oil blunts lung function decrements induced by acute exposure to ozone in young healthy adults: A randomized trial

Chen, H., Tong, H., Shen, W., Montilla, T., Case, M., Almond, M. A., Wells, H., Alexis, N. E., Peden, D. B., Rappold, A. G., et al. (2022) · Environment International · doi:10.1016/j.envint.2022.107407 · Cited by 30

Anti-inflammatory Activity of Saxifragin via Inhibition of NF-κB Involves Caspase-1 Activation

Cheon, S.-Y., Chung, K., Jeon, E., Nugroho, A., Park, H.-J., & An, H. (2015) · Journal of Natural Products · doi:10.1021/acs.jnatprod.5b00145 · Cited by 30

Clinical indices of in vivo biocompatibility: The role of ex vivo cell function studies and effluent markers in peritoneal dialysis patients

Mackenzie, R. K., Holmes, C. J., Jones, S., Williams, J. D., & Topley, N. (2003) · Kidney International · doi:10.1046/j.1523-1755.2003.08809.x · Cited by 30

Post‐reperfusion changes of monocyte function in coronary blood after extracorporeal circulation

Sbrana, S., Bevilacqua, S., Buffa, M., Spiller, D., Parri, M. S., Gianetti, J., Filippis, R. D., & Clerico, A. (2005) · Cytometry Part B Clinical Cytometry · doi:10.1002/cyto.b.20049 · Cited by 30

Protective effect of sophocarpine on lipopolysaccharide-induced acute lung injury in mice

Lü, Y., Xu, D., Liu, J., & Gu, L.-N. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.02.020 · Cited by 30

Ox-LDL Upregulates IL-6 Expression by Enhancing NF-κB in an IGF2-Dependent Manner in THP-1 Macrophages

Wang, Y., Hu, Y., Sha, Y.-H., Gao, J.-J., Ma, X., Li, S., Zhao, J., Qiu, Y., Lu, J., Huang, C., et al. (2015) · Inflammation · doi:10.1007/s10753-015-0194-1 · Cited by 30

Bacterial Clearance and Cytokine Profiles in a Murine Model of Postsurgical Nosocomial Pneumonia

Manderscheid, P. A., Bodkin, R. P., Davidson, B. A., Jensen, E. A., Russo, T. A., & Knight, P. R. (2004) · Clinical and Vaccine Immunology · doi:10.1128/cdli.11.4.742-751.2004 · Cited by 30

Immunotherapy Strategy for Systemic Autoimmune Diseases: Betting on CAR-T Cells and Antibodies

Chasov, V. V., Zmievskaya, E., Ganeeva, I., Gilyazova, E., Davletshin, D., Khaliulin, M., Kabwe, E., Davidyuk, Y. N., Valiullina, A., Rizvanov, A. A., et al. (2024) · Antibodies · doi:10.3390/antib13010010 · Cited by 29

Effect of alcohol on the interleukin 6-mediated inflammatory response in a new mouse model of acute-on-chronic liver injury

Karataylı, E., Hall, R. A., Weber, S. N., Dooley, S., & Lammert, F. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.11.008 · Cited by 29

Bax gene G(-248)A promoter polymorphism is associated with increased lifespan of the neutrophils of patients with osteomyelitis

Ocaña, M. G., Valle-Garay, E., Montes, A. H., Meana, Á., Carton, J. A., Fierer, J., Celada, A., & Asensi, V. (2007) · Genetics in Medicine · doi:10.1097/gim.0b013e318039b23d · Cited by 29

Anti-Inflammatory and Anti-Superbacterial Activity of Polyphenols Isolated from Black Raspberry

Kim, S. K., Kim, H., Kim, S. A., Park, H. K., & Kim, W. (2013) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2013.17.1.73 · Cited by 29

Anti-inflammatory phenolics isolated from Juniperus rigida leaves and twigs in lipopolysaccharide-stimulated RAW264.7 macrophage cells

Jeong, E. J., Seo, H., Yang, H., Kim, J., Sung, S. H., & Kim, Y. C. (2011) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756366.2011.625025 · Cited by 28

The feto‐maternal immune response to equine placentitis

Fedorka, C. E., Ball, B. A., Scoggin, K. E. S., Loux, S. C., Troedsson, M. H. T., & Adams, A. A. (2019) · American Journal of Reproductive Immunology · doi:10.1111/aji.13179 · Cited by 28

Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants

von Müller, C., Bulman, F., Wagner, L., Rosenberger, D., Marolda, A., Kurzai, O., Eißmann, P., Jacobsen, I. D., Perner, B., Hemmerich, P. H., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-78387-y · Cited by 28

Interleukin-6 expression and its modulation by diacerein in a rat model of chronic stress induced cardiac dysfunction

Agarwal, V., Kaushik, A., Rehman, M., Chaudhary, R., Jawaid, T., Kamal, M., & Mishra, V. (2021) · Heliyon · doi:10.1016/j.heliyon.2021.e08522 · Cited by 29

Propofol Reduces Lipopolysaccharide-Induced, NADPH Oxidase (NOX2) Mediated TNF-αand IL-6 Production in Macrophages

Meng, T., Yu, J., Lei, Z., Wu, J., Wang, S., Bo, Q., Zhang, X., Ma, Z., & Yu, J. (2013) · Clinical and Developmental Immunology · doi:10.1155/2013/325481 · Cited by 29

Serum Chitotriosidase, a Putative Marker of Chronically Activated Macrophages, Increases With Normal Aging

Ramanathan, R., Kohli, A., Ingaramo, M., Jain, A., Leng, S. X., Punjabi, N. M., Walston, J. D., & Fedarko, N. S. (2013) · The Journals of Gerontology Series A · doi:10.1093/gerona/glt022 · Cited by 28

Autoantibodies to neutrophil cytoplasmic antigens (ANCA) do not bind to polymorphonuclear neutrophils in blood

Abdel-Salam, B. K. A., Iking‐Konert, C., Schneider, M., Andrássy, K., & Hänsch, G. M. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00849.x · Cited by 28

Immunomodulatory/anti-inflammatory effects of Baccharis dracunculifolia leaves

Bachiega, T. F., Sousa, J. P., Bastos, J. K., & Sforcin, J. M. (2012) · Natural Product Research · doi:10.1080/14786419.2012.742078 · Cited by 27

Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities

Thi, N. N., Song, H. S., Oh, E.-J., Lee, Y., Ko, J., Kwon, J. E., Kang, S., Lee, D., Jung, I. H., & Baek, N. (2017) · Applied Biological Chemistry · doi:10.1007/s13765-017-0307-7 · Cited by 27

Positionspapier: Empfehlungen zur Anwendung von Omalizumab bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem – Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC)

Klimek, L., Förster‐Ruhrmann, U., Beule, A. G., Chaker, A. M., Hagemann, J., Huppertz, T., Hoffmann, T. K., Dazert, S., Deitmer, T., Olze, H., et al. (2021) · Laryngo-Rhino-Otologie · doi:10.1055/a-1644-4066 · Cited by 27

Overexpression of MMPs, cytokines, and RANKL/OPG in temporomandibular joint osteoarthritis and their association with joint pain, mouth opening, and bone degeneration: A preliminary report

Cafferata, E. A., Monasterio, G., Castillo, F. A., Carvajal, P., Flores, G., Diaz, W. R., Fuentes, A., & Vernal, R. (2020) · Oral Diseases · doi:10.1111/odi.13623 · Cited by 27

How Severe Anaemia Might Influence the Risk of Invasive Bacterial Infections in African Children

Abuga, K. M., Muriuki, J. M., Williams, T. N., & Atkinson, S. H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186976 · Cited by 32

Gingival crevicular fluid levels of cytokine, chemokine, and growth factors in patients with periodontitis or gingivitis and periodontally healthy subjects: a cross-sectional multiplex study

Gündoğar, H., Üstün, K., Şenyurt, S. Z., Özdemır, E. Ç., Sezer, U., & Ercıyas, K. (2021) · Central European Journal of Immunology · doi:10.5114/ceji.2021.110289 · Cited by 27

Indicating biologics for chronic rhinosinusitis with nasal polyps (CRSwNP)

Klimek, L., Förster‐Ruhrmann, U., Beule, A. G., Chaker, A. M., Hagemann, J., Klimek, F., Casper, I., Huppertz, T., Hoffmann, T. K., Dazert, S., et al. (2022) · Allergo Journal International · doi:10.1007/s40629-022-00220-x · Cited by 27

SR-BI in Bone Marrow Derived Cells Protects Mice from Diet Induced Coronary Artery Atherosclerosis and Myocardial Infarction

Pei, Y., Chen, X., Aboutouk, D., Fuller, M. T., Dadoo, O., Yu, P., White, E. J., Igdoura, S. A., & Trigatti, B. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072492 · Cited by 27

Vascular Endothelial Cell Injury Partly Induced by Mesenteric Lymph in Heat Stroke

Tong, H., Wan, P., Zhang, X.-Q., Duan, P.-K., Tang, Y., Chen, Y., Tang, L., & Su, L. (2013) · Inflammation · doi:10.1007/s10753-013-9708-x · Cited by 27

The efficacy and safety of selective leukocytapheresis in the treatment of ulcerative colitis: a meta-analysis

Zhu, M., Xu, X., Nie, F., Tong, J., Xiao, S., & Ran, Z. (2011) · International Journal of Colorectal Disease · doi:10.1007/s00384-011-1193-9 · Cited by 27

Serum chemokine levels as prognostic markers in patients with early systemic sclerosis: a multicenter, prospective, observational study

Hasegawa, M., Asano, Y., Endo, H., Fujimoto, M., Goto, D., Ihn, H., Inoue, K., Ishikawa, O., Kawaguchi, Y., Kuwana, M., et al. (2012) · Modern Rheumatology · doi:10.1007/s10165-012-0795-6 · Cited by 27

Cutaneous Leukemia Inhibitory Factor and Its Potential Role in the Development of Skin Tumors

McKenzie, R. C., & Szepietowski, J. C. (2004) · Dermatologic Surgery · doi:10.1097/00042728-200402002-00009 · Cited by 27

Serum chemokine levels as prognostic markers in patients with early systemic sclerosis: a multicenter, prospective, observational study

Hasegawa, M., Asano, Y., Endo, H., Fujimoto, M., Goto, D., Ihn, H., Inoue, K., Ishikawa, O., Kawaguchi, Y., Kuwana, M., et al. (2013) · Modern Rheumatology · doi:10.3109/s10165-012-0795-6 · Cited by 27

The crucial role of the MyD88 adaptor protein in the inflammatory response induced by Bothrops atrox venom

Moreira, V., Teixeira, C., da Silva, H. B., Lima, M. R. D., & Dos‐Santos, M. C. (2013) · Toxicon · doi:10.1016/j.toxicon.2013.02.010 · Cited by 27

Pathological and clinical effects of interleukin-6 on human myocarditis

Amioka, N., Nakamura, K., Kimura, T., Ohta‐Ogo, K., Tanaka, T., Toji, T., Akagi, S., Nakagawa, K., Toh, N., Yoshida, M., et al. (2021) · Journal of Cardiology · doi:10.1016/j.jjcc.2021.03.003 · Cited by 26

Blockade of the fractalkine–CX3CR1 axis ameliorates experimental colitis by dislodging venous crawling monocytes

Kuboi, Y., Nishimura, M., Ikeda, W., Nakatani, T., Seki, Y., Yamaura, Y., Ogawa, K., Hamaguchi, A., Muramoto, K., Mizuno, K., et al. (2019) · International Immunology · doi:10.1093/intimm/dxz006 · Cited by 27

Higher circulating vitamin B12 is associated with lower levels of inflammatory markers in individuals at high cardiovascular risk and in naturally aged mice

Domínguez‐López, I., Kovatcheva, M., Casas, R. M., Toledo, E., Fitó, M., Ros, E., Estruch, R., Serrano, M., & Lamuela-Raventós, R. M. (2023) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.12976 · Cited by 33

Older age and type of surgery predict the early inflammatory response to hip trauma mediated by interleukin-6 (IL-6)

Sedlář, M., Kudrnová, Z., Erhart, D., Trča, S., Kvasnička, J., Krška, Z., Mazoch, J., Malíková, I., Zeman, M., & Linhart, A. (2009) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2009.06.006 · Cited by 26

The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice

Hess, J. A., Zhan, B., Torigian, A., Patton, J. B., Petrovsky, N., Zhan, T., Bottazzi, M. E., Hotez, P. J., Klei, T. R., Lustigman, S., et al. (2016) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004797 · Cited by 26

Neutrophil infiltration and activation in bronchiolitic airways are independent of viral etiology

Cavallaro, E. C., Liang, K., Lawrence, M. D., Forsyth, K. D., & Dixon, D. (2016) · Pediatric Pulmonology · doi:10.1002/ppul.23514 · Cited by 26

The role of leukocyte-stromal interactions in chronic inflammatory joint disease

Burman, A. C., Haworth, O., Bradfield, P. F., Parsonage, G. N., Filer, A. D., Thomas, A. M. C., Amft, N., Salmon, M., & Buckley, C. D. (2004) · Joint Bone Spine · doi:10.1016/j.jbspin.2004.03.009 · Cited by 26

The Immunomodulatory Imbalance in Patients with Ketamine Cystitis

Fan, G.-Y., Cherng, J., Chang, S., Poongodi, R., Chang, A., Wu, S., & Meng, E. (2017) · BioMed Research International · doi:10.1155/2017/2329868 · Cited by 25

Glucagon-Like Peptide-1 Receptor Regulates Macrophage Migration in Monosodium Urate-Induced Peritoneal Inflammation

Chen, J., Mei, A., Liu, X., Braunstein, Z., Wei, Y., Wang, B., Duan, L., Rao, X., Rajagopalan, S., Dong, L., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.772446 · Cited by 25

Neutrophil and NETosis Modulation in Traumatic Heterotopic Ossification

Nunez, J. H., Juan, C., Sun, Y., Hong, J. Y., Bancroft, A. C., Hwang, C. D., Medrano, J. M. R., Huber, A. K., Tower, R. J., & Lévi, B. (2023) · Annals of Surgery · doi:10.1097/sla.0000000000005940 · Cited by 25

Interleukin‐6 levels in female rats with protamine sulfate‐induced chronic cystitis treated with hyaluronic acid

Lv, Y., Yao, Y., Lin, M., Lu, R., Deng, B.-H., Huang, J., & Hao, W. (2013) · International Journal of Urology · doi:10.1111/iju.12090 · Cited by 25

Selenium Pretreatment Alleviated LPS-Induced Immunological Stress Via Upregulation of Several Selenoprotein Encoding Genes in Murine RAW264.7 Cells

Wang, L., Jing, J., Yan, H., Tang, J., Jia, G., Liu, G., Chen, X., Tian, G., Cai, J., Shang, H., et al. (2018) · Biological Trace Element Research · doi:10.1007/s12011-018-1333-y · Cited by 28

A conceptual time window‐based model for the early stratification of trauma patients

Lamparello, A. J., Namas, R. A., Constantine, G. M., McKinley, T. O., Elster, E. A., Yoram Vodovotz, B., & Billiar, T. R. (2019) · Journal of Internal Medicine · doi:10.1111/joim.12874 · Cited by 26

Targeting inflammatory diseases via apoptotic mechanisms

Murphy, F. J. (2003) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(03)00072-9 · Cited by 25

Gene expression profile in pelvic organ prolapse

Brizzolara, S., Killeen, J. L., & Urschitz, J. (2008) · Molecular Human Reproduction · doi:10.1093/molehr/gan074 · Cited by 25

Interleukin-6, vascular endothelial growth factor and transforming growth factor beta 1 in canine steroid responsive meningitis-arteritis

Maiolini, A., Otten, M., Hewicker‐Trautwein, M., Carlson, R., & Tipold, A. (2013) · BMC Veterinary Research · doi:10.1186/1746-6148-9-23 · Cited by 25

A novel intrinsically disordered outer membrane lipoprotein ofAggregatibacter actinomycetemcomitansbinds various cytokines and plays a role in biofilm response to interleukin-1β and interleukin-8

Ahlstrand, T., Tuominen, H. K., Beklen, A., Torittu, A., Oscarsson, J., Sormunen, R. T., Pöllänen, M. T., Permi, P., & Ihalin, R. (2016) · Virulence · doi:10.1080/21505594.2016.1216294 · Cited by 25

IL-6, monocyte infiltration and parenchymal cells

Bartoccioni, E., Scuderi, F., Marino, M., & Provenzano, C. (2003) · Trends in Immunology · doi:10.1016/s1471-4906(03)00112-1 · Cited by 25

Alginate from Ericaria crinita Possesses Antioxidant Activity and Attenuates Systemic Inflammation via Downregulation of Pro-Inflammatory Cytokines

Lukova, P., Kokova, V., Baldzhieva, A., Murdjeva, M., Katsarov, P., Delattre, C., & Apostolova, E. (2024) · Marine Drugs · doi:10.3390/md22110482 · Cited by 24

IL ‐6 in the spotlight: From cardiovascular pathophysiology to therapy

Preda, A., Tirandi, A., Leo, G., Vece, D. D., Vilahur, G., Bonaventura, A., Osto, E., Ministrini, S., Kraler, S. C., Kleinbogard, P., et al. (2025) · European Journal of Clinical Investigation · doi:10.1111/eci.70161 · Cited by 26

Sensing sperm via maternal immune system: a potential mechanism for controlling microenvironment for fertility in the cow

Marey, M. A., Ezz, M. A., Akthar, I., Yousef, M. S., Imakawa, K., Shimada, M., & Miyamoto, A. (2020) · Journal of Animal Science · doi:10.1093/jas/skaa147 · Cited by 24

Hydrogen Sulfide Reduces Neutrophil Recruitment in Hind-Limb Ischemia-Reperfusion Injury in an L-Selectin and ADAM-17–Dependent Manner

Ball, C. J., Reiffel, A. J., Chintalapani, S., Kim, M., Spector, J. A., & King, M. R. (2013) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0b013e31827c6e9c · Cited by 24

Interstitial Granulomatous Dermatitis With Arthritis Responding to Tocilizumab

Schanz, S. (2012) · Archives of Dermatology · doi:10.1001/archdermatol.2011.341 · Cited by 24

Glucosyltransferases of Viridans Group Streptococci Modulate Interleukin-6 and Adhesion Molecule Expression in Endothelial Cells and Augment Monocytic Cell Adherence

Yeh, C., Chen, J., & Chia, J. (2006) · Infection and Immunity · doi:10.1128/iai.74.2.1273-1283.2006 · Cited by 24

Significant hepatic expression of IL-2 and IL-8 in biliary atresia compared with other neonatal cholestatic disorders

Arafa, R. S., Haie, O. M. A., Elazab, D., Abdelrahman, A. M. N., & Sıra, M. M. (2016) · Cytokine · doi:10.1016/j.cyto.2015.12.023 · Cited by 24

Disease progression in mice exposed to low-doses of aerosolized clinical isolates of Burkholderia pseudomallei

Treviño, S. R., Klimko, C. P., Reed, M. C., Aponte-Cuadrado, M. J., Hunter, M., Shoe, J. L., Meyer, J. R., Dankmeyer, J. L., Biryukov, S. S., Quirk, A. V., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0208277 · Cited by 24

Proinflammatory Cytokines and Signaling Pathways in Intestinal Innate Immune Cells

Sartor, R. B., & Hoentjen, F. (2005) · Elsevier eBooks · doi:10.1016/b978-012491543-5/50039-5 · Cited by 24

A polysaccharide purified from Radix Adenophorae promotes cell activation and pro-inflammatory cytokine production in murine RAW264.7 macrophages.

Li, J., Liu, Y., Li, B., Wang, Y.-Y., Wang, H., & Zhou, C. (2016) · PubMed · doi:10.3724/sp.j.1009.2016.00370 · Cited by 23

Dipsacus inermis Wall. modulates inflammation by inhibiting NF-κB pathway: An in vitro and in vivo study

Hassan, S., Sajjad, N., Khan, S. U., Gupta, S., Bhat, M. A., Ali, R., Ahmad, Z., Ganie, S. A., & Hamid, R. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.112710 · Cited by 23

Skeletal Muscle Interleukin-6 Contributes to the Innate Immune Response in Septic Mice

Laitano, O., Robinson, G. P., Garcia, C. K., Mattingly, A. J., Sheikh, L., Murray, K. O., Iwaniec, J., Alzahrani, J. M., Morse, D. A., Hidalgo, J., et al. (2020) · Shock · doi:10.1097/shk.0000000000001641 · Cited by 23

Immune response to Taenia solium cysticerci after anti-parasitic therapy

Singh, A. K., Singh, S. K., Singh, A., Gupta, K. K., Khatoon, J., Prasad, A., Rai, R. P., Gupta, R. K., Tripathi, M., Husain, N., et al. (2015) · International Journal for Parasitology · doi:10.1016/j.ijpara.2015.05.007 · Cited by 23

Proinflammatory cytokines and CD14 expression in mammary tissue of cows following intramammary inoculation of Panax ginseng at drying off

Baravalle, C., Dallard, B. E., Cadoche, M. C., Pereyra, E. A. L., Neder, V. E., Ortega, H. H., & Calvinho, L. F. (2011) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2011.07.003 · Cited by 24

Lack of Interleukin-6 Affects IFN-γ and TNF-α Production and Early In Vivo Control of Brucella abortus Infection

Guimarães, E. S., Martins, J. M., Gomes, M. T. R., Cerqueira, D. M., & Oliveira, S. C. (2020) · Pathogens · doi:10.3390/pathogens9121040 · Cited by 23

Calcitonin Gene-related Peptide Receptor Expression in Alternatively Activated Monocytes/Macrophages During Irreversible Pulpitis

Caviedes‐Bucheli, J., Moreno, G. C., López, M. P., Bermeo-Noguera, A. M., Pacheco-Rodríguez, G., Cuéllar, A., & Muñoz, H. R. (2008) · Journal of Endodontics · doi:10.1016/j.joen.2008.05.011 · Cited by 23

Roles of glucagon-like peptide 1 receptor agonists in immune cell biology and autoimmune/autoinflammatory diseases

Deng, S., Chen, Z., & Shi, Y. (2025) · Cell & Bioscience · doi:10.1186/s13578-025-01486-8 · Cited by 28

On-Demand Prolongation of Peripheral Nerve Blockade through Bupivacaine-Loaded Hydrogels with Suitable Residence Periods

Ning, C., Guo, Y., Yan, L., Thawani, J. P., Zhang, W., Fu, C., Liu, T., & Ding, J. (2018) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b01107 · Cited by 22

The influence of leukocyte-platelet-rich plasma on accelerated orthodontic tooth movement in rabbits

Nakornnoi, T., Leethanakul, C., & Samruajbenjakun, B. (2019) · The Korean Journal of Orthodontics · doi:10.4041/kjod.2019.49.6.372 · Cited by 22

Susceptibility Factors in Chronic Lung Inflammatory Responses to Engineered Nanomaterials

You, D. J., & Bonner, J. C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197310 · Cited by 24

IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms

Valín, Á., Rey, M. J. D., Municio, C., Usategui, A., Romero, M., Fernández-Felipe, J., Cañete, J. D. D., Blanco, F. J., Ruano, Y., Criado, G., et al. (2020) · BMC Molecular and Cell Biology · doi:10.1186/s12860-020-00317-7 · Cited by 22

Inhibitory Effects of Chloroform Extracts Derived from Corbicula fluminea on the Release of Pro-inflammatory Cytokines

Lin, C.-M., Lin, Y., Tsai, N., Wu, H.-Y., Ho, S.-Y., Chen, C., Liu, Y.-K., Chiu, Y., Ho, L.-P., Lee, R.-P., et al. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf2051202 · Cited by 23

Interleukin-6 promotes systemic lupus erythematosus progression with Treg suppression approach in a murine systemic lupus erythematosus model

Mao, X., Wu, Y., Diao, H., Hao, J., Tian, G., Jia, Z., Li, Z., Xiong, S., Wu, Z., Wang, P., et al. (2014) · Clinical Rheumatology · doi:10.1007/s10067-014-2717-9 · Cited by 22

Long-term endurance training increases serum cathepsin S and decreases IL-6 and hsCRP levels

Sponder, M., Campean, I., Emich, M., Fritzer‐Szekeres, M., Litschauer, B., Bergler-Klein, J. K., Graf, S., & Strametz‐Juranek, J. (2016) · Journal of Sports Sciences · doi:10.1080/02640414.2016.1258482 · Cited by 24

Interleukin-6 expression in disc derangement of human temporomandibular joint and association with osteoarthrosis

Camejo, F. D. A., de Azevedo, M. L. V., Ambros, V., Caporal, K. S. T., Doetzer, A. D., Almeida, L. E., Olandoski, M., de Noronha, L., & Trevilatto, P. C. (2017) · Journal of Cranio-Maxillofacial Surgery · doi:10.1016/j.jcms.2017.02.019 · Cited by 22

Effects of Porphyromonas gingivalis LipopolysaccharideTolerized Monocytes on Inflammatory Responses in Neutrophils

Zhu, X., Lu, W., Chen, Y., Cheng, X., Qiu, J., Xu, Y., & Sun, Y. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161482 · Cited by 22

Evolutionary clues to the functions of the Toll-like family as surveillance receptors

Johnson, G. B. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)00014-5 · Cited by 92

Role of Toll-like receptors in inflammatory response in macrophages

Aderem, A. A. (2001) · Critical Care Medicine · doi:10.1097/00003246-200107001-00008 · Cited by 106

The Toll receptor family and microbial recognition

Medzhitov, R. M., & Janeway, C. A. (2000) · Trends in Microbiology · doi:10.1016/s0966-842x(00)01845-x · Cited by 683

Toll-like receptors: a family of pattern-recognition receptors in mammals.

Armant, M. A., & Fenton, M. J. (2002) · Genome biology · doi:10.1186/gb-2002-3-8-reviews3011 · Cited by 196

Activation of Mammalian Toll-like Receptors by Endogenous Agonists

Johnson, G. B., Brunn, G. J., & Platt, J. L. (2003) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.v23.i12.20 · Cited by 143