IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

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IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.

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Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

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Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

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Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo

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Role of IL-6 and Its Soluble Receptor in Induction of Chemokines and Leukocyte Recruitment

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IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

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Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking

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Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation

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Lightly Cooked Broccoli Is as Effective as Raw Broccoli in Mitigating Dextran Sulfate Sodium-Induced Colitis in Mice

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Pathogenesis, attenuation, and treatment strategies for keloid management

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Anti-inflammatory and anti-oxidative activities of lemon myrtle (Backhousia citriodora) leaf extract

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Immunomodulatory and Mechanistic Considerations of Hibiscus sabdariffa (HS) in Dysfunctional Immune Responses: A Systematic Review

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Opuntia monacantha: Validation of the anti-inflammatory and anti-arthritic activity of its polyphenolic rich extract in silico and in vivo via assessment of pro- and anti-inflammatory cytokines

Abid, F., Saleem, M., Jamshaid, T., Jamshaid, U., Youssef, F. S., Diri, R. M., Elhady, S. S., & Ashour, M. L. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.117884 · Cited by 21

Orientia tsutsugamushi Infection Induces CD4+ T Cell Activation via Human Dendritic Cell Activity

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Immunologie der Polyposis nasi als Grundlage für eine Therapie mit Biologicals

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A Generic Coordination Assembly‐Enabled Nanocoating of Individual Tumor Cells for Personalized Immunotherapy

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Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications

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Short communication: Characterizing ovine serum stress biomarkers during endotoxemia

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Enhanced anti-inflammatory potential of cinnamate-zinc layered hydroxide in lipopolysaccharide-stimulated RAW 264.7 macrophages

Fakurazi, S., Adewoyin, M., Mohsin, S. M. N., Arulselvan, P., & Hussein, M. Z. (2015) · Drug Design Development and Therapy · doi:10.2147/dddt.s72716 · Cited by 21

Glutaminyl Cyclases as Novel Targets for the Treatment of Septic Arthritis

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Serum interleukin-6 levels are increased in HIV-infected patients that develop autoimmune disease during long-term follow-up

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HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells

Fujii, M., Kawashima, N., Tazawa, K., Hashimoto, K., Nara, K., Noda, S., Kuramoto, M., Orikasa, S., Nagai, S., & Okiji, T. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.11.032 · Cited by 21

Interplay between IFN-γ and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation

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In vivo immunological response of exposure to PEGylated graphene oxide via intraperitoneal injection

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A new p65 isoform that bind the glucocorticoid hormone and is expressed in inflammation liver diseases and COVID-19

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Myeloid cell-derived interleukin-6 induces vascular dysfunction and vascular and systemic inflammation

Knopp, T., Jung, R., Wild, J., Bochenek, M. L., Efentakis, P., Lehmann, A., Bieler, T., Garlapati, V. S., Richter, C., Molitor, M., et al. (2024) · European Heart Journal Open · doi:10.1093/ehjopen/oeae046 · Cited by 21

Respiratory tract toxicity of titanium dioxide nanoparticles and multi‐walled carbon nanotubes on mice after intranasal exposure

Sukwong, P., Somkid, K., Kongseng, S., Pissuwan, D., & Yoovathaworn, K. (2016) · Micro & Nano Letters · doi:10.1049/mnl.2015.0523 · Cited by 20

Modeling Adverse Birth Outcomes via Confirmatory Factor Quantile Regression

Burgette, L. F., & Reiter, J. P. (2011) · Biometrics · doi:10.1111/j.1541-0420.2011.01639.x · Cited by 20

Molecular analysis of the bovine anaphylatoxin C5a receptor

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Cytokine responses in broiler lines that differ in susceptibility to malabsorption syndrome

Rebel, J. M. J., Balk, F. R. M., & Boersma, W. J. A. (2005) · British Poultry Science · doi:10.1080/00071660500395541 · Cited by 20

Serum Cytokine Profiles Associated with Specific Adjuvants Used in a DNA Prime-Protein Boost Vaccination Strategy

Buglione‐Corbett, R., Pouliot, K., Marty-Roix, R., West, K., Wang, S., Lien, E., & Lu, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074820 · Cited by 19

Potential Immune Indicators for Predicting the Prognosis of COVID-19 and Trauma: Similarities and Disparities

Fouladseresht, H., Talepoor, A. G., Eskandari, N., Norouzian, M., Ghezelbash, B., Beyranvand, M. R., Nejadghaderi, S. A., Carson‐Chahhoud, K., Kolahi, A., & Safiri, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.785946 · Cited by 20

Anti-inflammatory effects of immature Citrus unshiu fruit extracts via suppression of NF-κB and MAPK signal pathways in LPS-induced RAW264.7 macrophage cells

Kim, M. G., Kim, S., Boo, K.-H., Kim, J., & Kim, C.-S. (2023) · Food Science and Biotechnology · doi:10.1007/s10068-023-01390-2 · Cited by 19

Targeting interleukin-6 as a treatment approach for peritoneal carcinomatosis

Dadgar, N., Sherry, C., Zimmerman, J., Park, H., Lewis, C. M., Donnenberg, A. D., Zaidi, A. H., Fan, Y., Xiao, K., Bartlett, D. L., et al. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05205-8 · Cited by 19

Anti-inflammatory activity of the ethanol extract of Dictamnus dasycarpus leaf in lipopolysaccharide-activated macrophages

Ghosh, C., Hong, B., Batabyal, S., Jeon, T., Yang, S. H., & Hwang, S. G. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-330 · Cited by 19

An Evaluation of the Stemness, Paracrine, and Tumorigenic Characteristics of Highly Expanded, Minimally Passaged Adipose-Derived Stem Cells

Atat, O. E., Antonios, D., Hilal, G., Hokayem, N. E., Ghoch, J. A., Hashim, H., Serhal, R., Hebbo, C., Moussa, M., & Alaaeddine, N. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162332 · Cited by 19

Analgesic and anti-inflammatory activities of methanolic extract of Mallotus repandus stem in animal models

Hasan, M. R., Uddin, N., Sana, T., Hossain, M. M., Mondal, M., Kanta, I. J., & Choudhuri, M. S. K. (2018) · Oriental Pharmacy and Experimental Medicine · doi:10.1007/s13596-018-0312-3 · Cited by 19

Therapeutic effect of a Chlamydia pecorum recombinant major outer membrane protein vaccine on ocular disease in koalas (Phascolarctos cinereus)

Nyari, S., Booth, R. J., Quigley, B. L., Waugh, C. A., & Timms, P. (2019) · PLoS ONE · doi:10.1371/journal.pone.0210245 · Cited by 19

Blockade of the fractalkine–CX3CR1 axis ameliorates experimental colitis by dislodging venous crawling monocytes

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Clinical Value of Serum Interleukin‐33 Biomarker in Infants With Neonatal Cholestasis

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The Use of Real Time rtPCR to Quantify Inflammatory Mediator Expression in Leukocytes from Patients with Severe Sepsis

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Serum interleukin-6 may modulate periodontal inflammation in type 1 diabetic subjects

Passoja, A., Knuuttila, M. L. E., Hiltunen, L. A., Karttunen, R. A., Niemelä, O. J., Raunio, T., Vainio, O., Hedberg, P. S. M., & Tervonen, T. (2011) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2011.01731.x · Cited by 19

Comparative Study of Litsea japonica Leaf and Fruit Extract on the Anti-inflammatory Effects

Namkoong, S., Jang, S., Sohn, E., Bak, J. P., Sohn, E., Koo, H. J., Yoon, W., Kwon, J. E., Jeong, Y. J., Xue, M., et al. (2015) · 한국자원식물학회지 · doi:10.7732/kjpr.2015.28.2.145 · Cited by 19

High cytokine levels in perforated acute otitis media exudates containing live bacteria

Skovbjerg, S., Roos, K., Nowrouzian, F. L., Lindh, M., Holm, S. E., Adlerberth, I., Olofsson, S., & Wold, A. E. (2010) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2010.03083.x · Cited by 19

In Vitro Cytotoxic and Inflammatory Response of Gingival Fibroblasts and Oral Mucosal Keratinocytes to 3D Printed Oral Devices

Kollmuß, M., Edelhoff, D., Schwendicke, F., & Wuersching, S. N. (2024) · Polymers · doi:10.3390/polym16101336 · Cited by 18

From Cytokines to Biomarkers: Mapping the Immunopathology of Inflammatory Bowel Disease

Baum, S., Hamedi, K. R., Loftus, C., Loftus, G., Zhou, E.-R., & Arce, S. (2025) · Cells · doi:10.3390/cells14201589 · Cited by 19

Mobility disorders and pain, interrelations that need new research concepts and advanced clinical commitments

Sajer, S. (2017) · European Journal of Translational Myology · doi:10.4081/ejtm.2017.7179 · Cited by 18

Marginal Zone B Cells Assist With Neutrophil Accumulation to Fight Against Systemic Staphylococcus aureus Infection

Lo, L.-W., Chang, C., Chiang, M.-F., Lin, I., & Lin, K. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.636818 · Cited by 20

Lycopene Inhibits Toll-Like Receptor 4-Mediated Expression of Inflammatory Cytokines in House Dust Mite-Stimulated Respiratory Epithelial Cells

Choi, J., Lim, J. W., & Kim, H. (2021) · Molecules · doi:10.3390/molecules26113127 · Cited by 18

The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment

Kalogera, S., He, Y., Bay‐Jensen, A., Gantzel, T., Sun, S., Manon‐Jensen, T., Karsdal, M. A., & Thudium, C. S. (2021) · Scientific Reports · doi:10.1038/s41598-021-03346-0 · Cited by 18

Novel Small Molecule Inhibitors Targeting the IL-6/STAT3 Pathway or IL-1β

Yoo, J., Kim, D., Park, J., Kim, Y.-K., Choo, H. P., & Woo, H. (2022) · Molecules · doi:10.3390/molecules27092696 · Cited by 15

Inbred and outbred mice have equivalent variability in a cockroach allergen-induced model of asthma.

Vaickus, L. J., Bouchard, J., Kim, J., Natarajan, S., & Remick, D. G. (2010) · PubMed Central · Cited by 18

Nano-titanium dioxide bioreactivity with human alveolar type-I-like epithelial cells: Investigating crystalline phase as a critical determinant

Sweeney, S. S., Berhanu, D., Ruenraroengsak, P., Thorley, A. J., Valsami‐Jones, E., & Tetley, T. D. (2014) · Nanotoxicology · doi:10.3109/17435390.2014.948518 · Cited by 18

5,6,7-Trimethoxyflavone suppresses pro-inflammatory mediators in lipopolysaccharide-induced RAW 264.7 macrophages and protects mice from lethal endotoxin shock

Rim, H.-K., Yun, C. H., Shin, J., Cho, Y., Jang, D. S., Ryu, J. H., Park, H., & Lee, K. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.10.025 · Cited by 18

Calcineurin B subunit triggers innate immunity and acts as a novel Engerix-B® HBV vaccine adjuvant

Hu, M., Su, Z., Yin, Y., Li, J., & Wei, Q. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.05.040 · Cited by 18

Anti-inflammatory and anti-biofilm properties of ent -nemorosone from Brazilian geopropolis

da Cunha, M. G., Franchin, M., de Paula-Eduardo, L. F., Freires, I. A., Beutler, J. A., de Alencar, S. M., Ikegaki, M., Tabchoury, C. P. M., Cunha, T. M., & Rosalen, P. L. (2016) · Journal of Functional Foods · doi:10.1016/j.jff.2016.07.009 · Cited by 18

Intermittent hypoxia‐induced epiregulin expression by IL ‐6 production in human coronary artery smooth muscle cells

Kyotani, Y., Itaya‐Hironaka, A., Yamauchi, A., Sakuramoto‐Tsuchida, S., Makino, M., Takasawa, S., & Yoshizumi, M. (2018) · FEBS Open Bio · doi:10.1002/2211-5463.12430 · Cited by 17

Synovial fluid calprotectin performs better than synovial fluid polymerase chain reaction and interleukin-6 in the diagnosis of periprosthetic joint infection

Cheok, T. S., Smith, T., Siddiquee, S., Jennings, M. P., Jayasekera, N., & Jaarsma, R. L. (2022) · The Bone & Joint Journal · doi:10.1302/0301-620x.104b3.bjj-2021-1320.r1 · Cited by 18

Sexual Dimorphism on Cytokines Expression in the Temporomandibular Joint: The Role of Gonadal Steroid Hormones

Torres-Chávez, K. E., Fischer, L., Teixeira, J. M., Moreira, N. C. F., Obando-Pereda, G. A., Parada, C. A., & Tambeli, C. H. (2010) · Inflammation · doi:10.1007/s10753-010-9256-6 · Cited by 18

Anti-resorptive saurolactam exhibits in vitro anti-inflammatory activity via ERK-NF-kappaB signaling pathway.

Lee, S.-U., Choi, Y.-O.-H., Kim, Y. S., Min, Y., Rhee, M., & Kim, S. (2010) · International Immunopharmacology · doi:10.1016/j.intimp.2009.11.014 · Cited by 18

Angiostatic and Angiogenic Chemokines in Systemic Sclerosis: An Overview

Bellando-Randone, S., George, J., Mazzotta, C., Guiducci, S., Furst, D. E., Mor, A., & Matucci‐Cerinic, M. (2016) · Journal of Scleroderma and Related Disorders · doi:10.5301/jsrd.5000226 · Cited by 18

High cytokine levels in perforated acuteotitis mediaexsudates containing live bacteria

Skovbjerg, S., Roos, K., Nowrouzian, F. L., Lindh, M., Holm, S. E., Adlerberth, I., Olofsson, S., & Wold, A. E. (2009) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2009.03083.x · Cited by 18

Production of IL-6, in contrast to other cytokines and chemokines, in macrophage innate immune responses: Effect of serum and fungal (Blastomyces) challenge

Brummer, E., Capilla, J., Bythadka, L., & Stevens, D. A. (2007) · Cytokine · doi:10.1016/j.cyto.2007.07.001 · Cited by 19

Screening of NO Inhibitor Release Activity from Soft Coral Extracts Origin Palu Bay, Central Sulawesi, Indonesia

Tanod, W. A., Yanuhar, U., Maftuch, Putra, M. Y., & Risjani, Y. (2019) · Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry · doi:10.2174/1871523018666190222115034 · Cited by 21

Therapeutic pathomorphosis in malignant glioma tissues after photodynamic therapy with сhlorin e6 (reports of two clinical cases)

Rynda, A. Y., Михайлович, Р. Д., Olyushin, V. E., & Zabrodskaya, Y. M. (2020) · Biomedical Photonics · doi:10.24931/2413-9432-2020-9-2-45-54 · Cited by 17

Caspase-1-Dependent Pyroptosis Mediates Adjuvant Activity of Platycodin D as an Adjuvant for Intramuscular Vaccines

Zhu, L., Han, Z., He, Y., & Sun, H. (2022) · Cells · doi:10.3390/cells11010134 · Cited by 17

Deconvolution of malignant pleural effusions immune landscape unravels a novel macrophage signature associated with worse clinical outcome in lung adenocarcinoma patients

Bruschini, S., Pallocca, M., Sperandio, E., D’Ambrosio, L., Ascenzi, F., Vitis, C. D., Salvati, V., Esposito, A., Martino, S. D., Nicola, F. D., et al. (2022) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2021-004239 · Cited by 17

Skin-Derived ABCB5+ Mesenchymal Stem Cells for High-Medical-Need Inflammatory Diseases: From Discovery to Entering Clinical Routine

Niebergall‐Roth, E., Frank, N. Y., Ganss, C., Frank, M. H., & Kluth, M. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010066 · Cited by 20

Biomarkers of Stress and Inflammation in Children

Davis, S., Latimer, M. N., & Rice, M. H. (2023) · Biological Research For Nursing · doi:10.1177/10998004231168805 · Cited by 21

Relationship between high white blood cell count and insulin resistance (HOMA-IR) in Korean children and adolescents: Korean National Health and Nutrition Examination Survey 2008–2010

Park, J. M., Lee, D., & Lee, Y. (2017) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2017.03.002 · Cited by 17

Cancer therapy-related cardiac dysfunction: is endothelial dysfunction at the heart of the matter?

Ching, C., Gustafson, D., Thavendiranathan, P., & Fish, J. E. (2021) · Clinical Science · doi:10.1042/cs20210059 · Cited by 17

Newly recruited human monocytes have a preserved responsiveness towards bacterial peptides in terms of CD11b up-regulation and intracellular hydrogen peroxide production

Dadfar, E., Jacobson, S. H., & Lundahl, J. (2007) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2007.03373.x · Cited by 16

Red Maca ( Lepidium meyenii ), a Plant from the Peruvian Highlands, Promotes Skin Wound Healing at Sea Level and at High Altitude in Adult Male Mice

Nuñez, D., Olavegoya, P., Gonzales, G. F., & Gonzales‐Castañeda, C. (2017) · High Altitude Medicine & Biology · doi:10.1089/ham.2017.0038 · Cited by 16

BMP-7, MMP-9, and TGF-β tissue remodeling proteins and their correlations with interleukins 6 and 10 in chronic rhinosinusitis

Lucas, B. R., Voegels, R. L., do Amaral, J. B., Bachi, A. L. L., & Pezato, R. (2021) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-021-06722-8 · Cited by 16

Exploring the Therapeutic Potential of Ampelopsis grossedentata Leaf Extract as an Anti-Inflammatory and Antioxidant Agent in Human Immune Cells

Chervet, A., Nehme, R., Decombat, C., Longechamp, L., Habanjar, O., Rousset, A., Fraisse, D., Blavignac, C., Filaire, E., Berthon, J., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010416 · Cited by 16

Contribution of interleukins in the regulation of teleost fish immunity: A review from the perspective of regulating macrophages

Cao, J.-F., Yang, G., Zhang, Y., & Chen, J. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110173 · Cited by 17

An Anti-Interleukin-2 Receptor Drug Attenuates T- Helper 1 Lymphocytes-Mediated Inflammation in an Acute Model of Endotoxin-Induced Uveitis

Mérida, S., Sancho‐Tello, M., Návea, A., Almansa, I., Muriach, M., & Bosch‐Morell, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090216 · Cited by 17

Neutrophil secretion modulates neutrophil and monocyte functions during hyperglucose and/or hyperinsulin conditions in vitro

Raj, P. N., Shaji, B. V., Haritha, V., & Anie, Y. (2018) · Journal of Cellular Immunotherapy · doi:10.1016/j.jocit.2018.02.001 · Cited by 16

Ca2+release-activated Ca2+channels are responsible for histamine-induced Ca2+entry, permeability increase, and interleukin synthesis in lymphatic endothelial cells

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A Neonatal Murine Escherichia coli Sepsis Model Demonstrates That Adjunctive Pentoxifylline Enhances the Ratio of Anti- vs. Pro-inflammatory Cytokines in Blood and Organ Tissues

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