The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.
Diagnostic point-of-care tests in resource-limited settings
Open accessAbstract
Diagnostic point-of-care (POC) testing is intended to minimize the time to obtain a test result, thereby allowing clinicians and patients to make an expeditious clinical decision. As POC tests expand into resource-limited settings (RLS), the benefits must outweigh the costs. To optimize POC testing in RLS, diagnostic POC tests need rigorous evaluations focused on relevant clinical outcomes and operational costs, which differ from evaluations of conventional diagnostic tests. Here, we reviewed published studies on POC testing in RLS, and found no clearly defined metric for the clinical utility of POC testing. Therefore, we propose a framework for evaluating POC tests, and suggest and define the term “test efficacy” to describe a diagnostic test’s capacity to support a clinical decision within its operational context. We also proposed revised criteria for an ideal diagnostic POC test in resource-limited settings. Through systematic evaluations, comparisons between centralized diagnostic testing and novel POC technologies can be more formalized, and health officials can better determine which POC technologies represent valuable additions to their clinical programs.
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Cited by
Becherer, L., Borst, N., Bakheit, M., Frischmann, S., Zengerle, R., & von Stetten, F. (2020) · Analytical Methods · doi:10.1039/c9ay02246e · Cited by 429
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Beyond the lateral flow assay: A review of paper-based microfluidics
Carrell, C., Kava, A., Nguyen, M., Menger, R., Munshi, Z., Call, Z., Nussbaum, M., & Henry, C. (2019) · Microelectronic Engineering · doi:10.1016/j.mee.2018.12.002 · Cited by 336
Recent advances in molecularly imprinted polymer-based electrochemical sensors
Li, Y., Luo, L., Kong, Y., Li, Y., Wang, Q., Wang, M., Li, Y., Davenport, A., & Li, B. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116018 · Cited by 308
Rapid Detection of Mycobacterium tuberculosis by Recombinase Polymerase Amplification
Boyle, D. S., McNerney, R., Teng Low, H., Leader, B. T., Pérez-Osorio, A. C., Meyer, J. C., O'Sullivan, D. M., Brooks, D. G., Piepenburg, O., & Forrest, M. S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103091 · Cited by 164
Metadata
- Authors
- Drain, P. K., Hyle, E. P., Noubary, F., Freedberg, K. A., Wilson, D., Bishai, W. R., Rodriguez, W., & Bassett, I. V.
- Venue
- The Lancet Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 14
- Issue
- 3
- Pages
- 239-249
- ISSN
- 1473-3099 (ISSN-L)
- OpenAlex
- W2119525065
- Cited by
- 744
- References
- 117
- FWCI
- 16.32
- Type
- journal article
- Language
- en
- Open access
- green
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- Drain, P. K., Hyle, E. P., Noubary, F., Freedberg, K. A., Wilson, D., Bishai, W. R., Rodriguez, W., & Bassett, I. V. (2014). Diagnostic point-of-care tests in resource-limited settings. The Lancet Infectious Diseases. https://doi.org/10.1016/s1473-3099(13)70250-0
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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