Diagnosis, prognosis, and clinical management of mild traumatic brain injury
Abstract
Concussion and mild traumatic brain injury (TBI) are interchangeable terms to describe a common disorder with substantial effects on public health. Advances in brain imaging, non-imaging biomarkers, and neuropathology during the past 15 years have required researchers, clinicians, and policy makers to revise their views about mild TBI as a fully reversible insult that can be repeated without consequences. These advances have led to guidelines on management of mild TBI in civilians, military personnel, and athletes, but their widespread dissemination to clinical management in emergency departments and community-based health care is still needed. The absence of unity on the definition of mild TBI, the scarcity of prospective data concerning the long-term effects of repeated mild TBI and subconcussive impacts, and the need to further develop evidence-based interventions to mitigate the long-term sequelae are areas for future research that will improve outcomes, reduce morbidity and costs, and alleviate delayed consequences that have only recently come to light.
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Clinical practice guidelines for mTBI underscore the importance of multidisciplinary rehabilitation of PPCS including the provision of mental health treatments, such as psychology.
“clinical practice guidelines for mTBI underscore the importance of multidisciplinary rehabilitation of PPCS including the provision of mental health treatments, such as psychology.”
From Acceptance and commitment therapy for mild traumatic brain injury (ACTion-mTBI): a quasiexperimental feasibility study (2025) · cites this paper as [23]
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Polinder, S., Cnossen, M. C., Real, R. G. L., Covic, A., Gorbunova, A., Voormolen, D. C., Master, C. L., Haagsma, J. A., Diaz-Arrastia, R., & von Steinbuechel, N. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.01113 · Cited by 376 · see citing works
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Does the fear avoidance model explain persistent symptoms after traumatic brain injury?
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Post-Traumatic Hypopituitarism: A Neglected Consequence of Traumatic Brain Injury
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- Authors
- Levin, H. S., & Diaz-Arrastia, R. R.
- Affiliations
- Michael E. DeBakey VA Medical Center (US)
- Uniformed Services University of the Health Sciences (US)
- Corresponding author
- Levin, Harvey S
- Venue
- The Lancet Neurology
- Publisher
- Elsevier BV
- Published
- 2015-05
- Volume
- 14
- Issue
- 5
- Pages
- 506-517
- ISSN
- 1474-4422 (ISSN-L)
- OpenAlex
- W1981337226
- Cited by
- 535
- References
- 89
- Citations by year
- 2026: 29 · 2025: 46 · 2024: 60 · 2023: 53 · 2022: 60 · 2021: 63 · 2020: 59 · 2019: 44 · 2018: 40 · 2017: 41 · 2016: 30 · 2015: 9
- FWCI
- 5.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (P01NS056202)
- Topics
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Automotive and Human Injury Biomechanics
- Keywords
- mild traumatic brain injury, concussion, diagnosis, prognosis, clinical management, biomarkers, neuroimaging, neuropathology, subconcussive impacts, long-term sequelae, military personnel, athletes, emergency department care, community-based care
- MeSH terms
- Adolescent, Adult, Brain Injuries, Child, Child, Preschool, Humans, Infant, Middle Aged, Practice Guidelines as Topic, Young Adult
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