Gastric accommodation and emptying in evaluation of patients with upper gastrointestinal symptoms
Open accessAbstract
Background & aims Endoscopy-negative dyspepsia is a common symptom that often is difficult to define in pathophysiologic terms. The aim of this study was to assess the frequency of disordered gastric accommodation and emptying in patients referred with unexplained upper gastrointestinal symptoms.Methods A computerized diagnostic index was used to identify all patients, 18-70 years old, who underwent single-photon emission computed tomography (SPECT) to assess gastric accommodation at Mayo Clinic Rochester over a 3-year period. Demographics, clinical features, and results of diagnostic testing, including scintigraphic gastric emptying, were extracted from the electronic record.Results A total of 214 patients were identified; the primary clinical diagnoses were functional dyspepsia, postfundoplication syndromes, rumination syndrome, and diabetic dyspepsia. Gastric accommodation was impaired in 43% of the whole group: 47% of functional dyspepsia, 44% of postfundoplication syndromes, and 33% of diabetic dyspepsia. Delayed gastric emptying was most prevalent in diabetic dyspepsia, and was accelerated in postfundoplication syndromes groups. Thirty-seven percent of patients had abnormal gastric emptying. The highest prevalence of delayed gastric emptying was in the diabetic dyspepsia and accelerated gastric emptying in postfundoplication syndromes groups. Twenty-five percent of patients with normal gastric emptying had impaired accommodation. Upper-gastrointestinal symptoms were not different in groups based on gastric accommodation or emptying results.Conclusions Impaired gastric accommodation is common in patients with unexplained dyspepsia. Symptoms alone cannot predict physiologic disturbances. These noninvasive tests identify single or combined pathophysiologic disturbances and may help to identify subgroups of patients as candidates for more selective pharmacotherapy in the future.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Altered GI motility and transit have long been recognized in the pathobiology of FGIDs such as IBS and functional dyspepsia.
“Altered GI motility and transit have long been recognized in the pathobiology of FGIDs such as IBS48 and functional dyspepsia (FD)49, 50.”
From The gut Microbiome in adult and pediatric functional gastrointestinal disorders (2019) · cites this paper as [50]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Role of impaired gastric accommodation to a meal in functional dyspepsia
Tack, J. F., Piessevaux, H. H., Coulie, B. J., Caenepeel, P., & Janssens, J. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70012-5 · Cited by 1,061 · see citing works
Assessment of gastric emptying using a low fat meal: establishment of international control values
Tougas, G., Eaker, E., Abell, T., Abrahamsson, H., Boivin, M., Chen, J.-D. D. Z., Hocking, M., Quigley, E., Koch, K., Tokayer, A., et al. (2000) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.02076.x · Cited by 645 · see citing works
Risk indicators of delayed gastric emptying of solids in patients with functional dyspepsia
Stanghellini, V., Tosetti, C., Paternicò, A., Barbara, G., Morselli‐Labate, A. M., Monetti, N., Marengo, M., & Corinaldesi, R. (1996) · Gastroenterology · doi:10.1053/gast.1996.v110.pm8612991 · Cited by 626 · see citing works
Single photon-emission computed tomography
Holly, T. A., Abbott, B., Al-Mallah, M. H., Calnon, D. A., Cohen, M. C., DiFilippo, F. P., Ficaro, E. P., Freeman, M. R., Hendel, R. C., Jain, D., et al. (2010) · Journal of Nuclear Cardiology · doi:10.1007/s12350-010-9246-y · Cited by 603 · see citing works
Functional Esophageal Disorders
Galmiche, J. P., Clouse, R. E., Bálint, A. F., Cook, I. J., Kahrilas, P. J., Paterson, W. G., & Smout, A. J. P. M. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.08.060 · Cited by 599 · see citing works
Gastric Tone Measured by an Electronic Barostat in Health arid Postsurgical Gastroparesis
Azpiroz, F., & Malagelada, J. (1987) · Gastroenterology · doi:10.1016/0016-5085(87)90967-x · Cited by 358 · see citing works
Impaired accommodation of proximal stomach to a meal in functional dyspepsia
Gilja, O. H., Hausken, T., Wilhelmsen, I., & Berstad, A. (1996) · Digestive Diseases and Sciences · doi:10.1007/bf02213124 · Cited by 287 · see citing works
Talley, N. J., Verlinden, M. H., Snape, W. J., Beker, J. A., Ducrotte, P. R., Dettmer, A., Brinkhoff, H., Eaker, E. Y., Ohning, G., Miner, P. B., et al. (2000) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2000.00868.x · Cited by 221 · see citing works
Bouras, E. P., Delgado-Aros, S., Camilleri, M., Castillo, E. J., Burton, D. D., Thomforde, G. M., & Chial, H. J. (2002) · Gut · doi:10.1136/gut.51.6.781 · Cited by 218 · see citing works
Self-citationDisturbed solid-phase gastric emptying in functional dyspepsia: a meta-analysis
Quarter, A. O., De Wit, N. J., Lodder, A. C., Numans, M. E., Smout, A. J. P. M., & Hoes, A. W. (1998) · Digestive Diseases and Sciences · doi:10.1023/a:1018803129779 · Cited by 209 · see citing works
Responses to gastric distension in functional dyspepsia
SALET, G., Samsom, M., Roelofs, J. M. M., Henegouwen, G. P. V. B., Smout, A. J. P. M., & Akkermans, L. M. A. (1998) · Gut · doi:10.1136/gut.42.6.823 · Cited by 207 · see citing works
Rumination Syndrome in Children and Adolescents: Diagnosis, Treatment, and Prognosis
Chial, H. J., Camilleri, M., Williams, D. E., Litzinger, K., & Perrault, J. F. (2003) · PEDIATRICS · doi:10.1542/peds.111.1.158 · Cited by 205 · see citing works
Self-citationTowards a less costly but accurate test of gastric emptying and small bowel transit
Camilleri, M., Zinsmeister, A. R., Greydanus, M. P., Brown, M. L., & Proano, M. (1991) · Digestive Diseases and Sciences · doi:10.1007/bf01297027 · Cited by 198 · see citing works
Self-citationBoeckxstaens, G. E., Hirsch, D. P., van den Elzen, B. D. J., Heisterkamp, S. H., & Tytgat, G. N. J. (2001) · Gastroenterology · doi:10.1053/gast.2001.28656 · Cited by 184 · see citing works
Cremonini, F., Mullan, B. P., Camilleri, M., Burton, D. D., & Rank, M. (2002) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2002.01344.x · Cited by 183 · see citing works
Self-citationThe rumination syndrome: Clinical features rather than manometric diagnosis
O'Brien, M. D., Bruce, B. K., & Camilleri, M. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90199-x · Cited by 183 · see citing works
Self-citationCorinaldesi, R., Stanghellini, V., Raiti, C., Rea, E., Salgemini, R., & Barbara, L. (1987) · Gut · doi:10.1136/gut.28.3.300 · Cited by 182 · see citing works
Development of a test to measure gastric accommodation in humans
Kuiken, S. D., Samsom, M., Camilleri, M., Mullan, B. P., Burton, D. D., Kost, L. J., Hardyman, T. J., Brinkmann, B. H., & O’Connor, M. K. (1999) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1999.277.6.g1217 · Cited by 178 · see citing works
Self-citationDefinition and investigation of dyspepsia
Barbara, L., Camilleri, M., Corinaldesi, R., Crean, G. P., Heading, R. C., Johnson, A. G., Malagelada, J., Stanghellini, V., & WIENBECK, M. (1989) · Digestive Diseases and Sciences · doi:10.1007/bf01537277 · Cited by 178 · see citing works
Self-citationNoninvasive measurement of gastric accommodation in patients with idiopathic nonulcer dyspepsia
Kim, D.-Y., Delgado-Aros, S., Camilleri, M., Samsom, M., Murray, J. A., O’Connor, M. K., Brinkmann, B. H., Stephens, D. A., Lighvani, S. S., & Burton, D. D. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.05264.x · Cited by 158 · see citing works
Self-citationFrank, J. W., Saslow, S. B., Camilleri, M., Thomforde, G. M., Dinneen, S. F., & Rizza, R. A. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90382-8 · Cited by 157 · see citing works
Self-citationTroncon, L. E. D. A., Thompson, D. G., Ahluwalia, N., Barlow, J. D., & Heggie, L. (1995) · Gut · doi:10.1136/gut.37.1.17 · Cited by 154 · see citing works
Thumshirn, M., Camilleri, M., Saslow, S. B., Williams, D. E., Burton, D. D., & Hanson, R. B. (1999) · Gut · doi:10.1136/gut.44.1.55 · Cited by 152 · see citing works
Self-citationThe proximal stomach and postprandial symptoms in functional dyspeptics
Boeckxstaens, G. E., Hirsch, D. P., Kuiken, S. D., Heisterkamp, S. H., & Tytgat, G. N. J. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05421.x · Cited by 150 · see citing works
Lack of Association Between Gastric Emptying of Solids and Symptoms in Nonulcer Dyspepsia
Talley, N. J., Shuter, B., McCrudden, G., Jones, M., Hoschl, R., & Piper, D. W. (1989) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-198912000-00005 · Cited by 143 · see citing works
Neurohormonal Factors in Functional Dyspepsia: Insights on Pathophysiological Mechanisms
Greydanus, M. P., Vassallo, M., Camilleri, M., Nelson, D. K., Hanson, R. B., & Thomforde, G. M. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)70018-s · Cited by 138 · see citing works
Self-citationCompliance of the proximal stomach and dyspeptic symptoms in patients with type I diabetes mellitus
Samsom, M., SALET, G., Roelofs, J. M. M., Akkermans, L. M. A., Henegouwen, G. P. V. B., & Smout, A. J. P. M. (1995) · Digestive Diseases and Sciences · doi:10.1007/bf02208676 · Cited by 136 · see citing works
Functional esophageal disorders
Clouse, R. E., Richter, J. E., Heading, R. C., Janssens, J., & Wilson, J. A. (1999) · Gut · doi:10.1136/gut.45.2008.ii31 · Cited by 131 · see citing works
Division of Short Gastric Vessels at Laparoscopic Nissen Fundoplication
OBoyle, C., Watson, D. I., Jamieson, G. G., Myers, J. C., Game, P. A., & Devitt, P. G. (2002) · Annals of Surgery · doi:10.1097/00000658-200202000-00001 · Cited by 123 · see citing works
Haug, T. T., Svebak, S., Hausken, T., Wilhelmsen, I., Berstad, A., & Ursin, H. (1994) · Psychosomatic Medicine · doi:10.1097/00006842-199405000-00001 · Cited by 123 · see citing works
Symptomatic, radionuclide and therapeutic assessment of chronic idiopathic dyspepsia
Jian, R., Ducrot, F., Ruskoné, A., Chaussade, S., Rambaud, J., Modigliani, R., Rain, J., & Bernier, J.-J. (1989) · Digestive Diseases and Sciences · doi:10.1007/bf01540334 · Cited by 122 · see citing works
Vu, M. K., Straathof, J. W. A., Schaar, P. J. V. D., Arndt, J. W., Ringers, J., Lamers, C. B. H. W., & Masclee, A. (1999) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.1130_f.x · Cited by 111 · see citing works
Tougas, G. H., Chen, Y., Coates, G., Paterson, W. G., Dallaire, C., Paré, P., Boivin, M., Watier, A., Daniels, S., & Diamant, N. E. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01703.x · Cited by 110 · see citing works
Samsom, M., Roelofs, J. M. M., Akkermans, L. M. A., Henegouwen, G. P. V. B., & Smout, A. J. P. M. (1998) · Digestive Diseases and Sciences · doi:10.1023/a:1018894520557 · Cited by 106 · see citing works
Gastric mechanosensory and lower esophageal sphincter function in rumination syndrome
Thumshirn, M., Camilleri, M., Hanson, R. B., Williams, D. E., Schei, A. J., & Kammer, P. P. (1998) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1998.275.2.g314 · Cited by 106 · see citing works
Self-citationNon-invasive measurement of gastric accommodation in humans
Schwizer, W., Steingoetter, A., Fox, M. R., Zur, T., Thumshirn, M., Boesiger, P., & Fried, M. (2002) · Gut · doi:10.1136/gut.51.suppl_1.i59 · Cited by 102 · see citing works
Kim, D.-Y., Myung, S., & Camilleri, M. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.03346.x · Cited by 98 · see citing works
Self-citationFundoplication Enhances Gastric Emptying
Maddern, G., & Jamieson, G. (1985) · Annals of Surgery · doi:10.1097/00000658-198503000-00006 · Cited by 84 · see citing works
Delgado-Aros, S., Vella, A. V., Camilleri, M., Low, P. A., Burton, D. D., Thomforde, G. M., & Stephens, D. A. (2003) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.2003.00422.x · Cited by 79 · see citing works
Self-citationFunction of the proximal stomach after Nissen fundoplication
Wijnhoven, B. P. L., SALET, G., Roelofs, J. M. M., Smout, A. J. P. M., Akkermans, L. M. A., & Gooszen, H. G. (1998) · British journal of surgery · doi:10.1046/j.1365-2168.1998.00505.x · Cited by 68 · see citing works
Advances in diabetic gastroparesis.
Camilleri, M. (2002) · PubMed · Cited by 56 · see citing works
Self-citationPharmacological modulation of human gastric volumes demonstrated noninvasively using SPECT imaging
Liau, S., Camilleri, M., Kim, D.-Y., Stephens, D., Burton, D., & O'Connor, M. (2001) · Neurogastroenterology and Motility · doi:10.1046/j.1365-2982.2001.00287.x · Cited by 56 · see citing works
Self-citationShunt Fascicles in the Gastric Myenteric Plexus in Five Species
Christensen, J. C., & Rick, G. A. (1985) · Gastroenterology · doi:10.1016/s0016-5085(85)80023-8 · Cited by 15 · see citing works
Rumination Syndrome in Children and Adolescents
Dershewitz, R. (2000) · Journal watch · doi:10.1056/jw200005120000006 · Cited by 4 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- O'Brien MD, Bruce BK, Camilleri M. Rumination syndrome: clini- cal features rather than manometric diagnosis. Gastroenterology 1995;108:1024 -1029.
Cited by
Sorted by citations
Clinical Guideline: Management of Gastroparesis
Camilleri, M., Parkman, H. P., Shafi, M. A., Abell, T. L., & Gerson, L. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2012.373 · Cited by 1,149 · see citing works
Self-citationJung, H., Choung, R. S., Locke, G. R., Schleck, C. D., Zinsmeister, A. R., Szarka, L. A., Mullan, B., & Talley, N. J. (2009) · Gastroenterology · doi:10.1053/j.gastro.2008.12.047 · Cited by 571 · see citing works
Self-citationAmerican Gastroenterological Association Technical Review on the Evaluation of Dyspepsia
Talley, N. J., Vakil, N. B., & Moayyedi, P. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.09.020 · Cited by 436 · see citing works
Rao, S. S. C., Camilleri, M., Hasler, W. L., Maurer, A. H., Parkman, H. P., Saad, R., Scott, S. M., Simrén, M., Soffer, E., & Szarka, L. A. (2010) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2010.01612.x · Cited by 383 · see citing works
Self-citationAbell, T. L., Bernstein, V. K., Cutts, T., Farrugia, G., Forster, J., Hasler, W. L., Mccallum, R. W., Olden, K. W., Parkman, H. P., Parrish, C. R., et al. (2006) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00760.x · Cited by 361 · see citing works
Functional dyspepsia, delayed gastric emptying, and impaired quality of life
Talley, N. J., Locke, G. R., Lahr, B. D., Zinsmeister, A. R., Tougas, G., Ligozio, G., Rojavin, M. A., & Tack, J. F. (2005) · Gut · doi:10.1136/gut.2005.078634 · Cited by 283 · see citing works
Camilleri, M., Bharucha, A. E., Ueno, R., Burton, D., Thomforde, G. M., Baxter, K., McKinzie, S., & Zinsmeister, A. R. (2006) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00264.2005 · Cited by 253 · see citing works
Self-citationBharucha, A. E., Kudva, Y. C., & Prichard, D. O. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00161 · Cited by 252 · see citing works
Impaired gastric accommodation and its role in dyspepsia
Kindt, S., & Tack, J. F. (2006) · Gut · doi:10.1136/gut.2005.085365 · Cited by 221 · see citing works
Vijayvargiya, P., Jameie-oskooei, S., Camilleri, M., Chedid, V. G., Erwin, P., & Murad, M. (2018) · Gut · doi:10.1136/gutjnl-2018-316405 · Cited by 190 · see citing works
Self-citationVella, A. V., Bock, G., Giesler, P. D., Burton, D. B., Serra, D. B., Ligueros‐Saylan, M., Dunning, B. E., Foley, J. E., Rizza, R. A., & Camilleri, M. (2007) · Diabetes · doi:10.2337/db07-0136 · Cited by 200 · see citing works
Self-citationFord, A. C., Marwaha, A., Lim, A., & Moayyedi, P. (2010) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.07.020 · Cited by 195 · see citing works
Current management strategies and emerging treatments for functional dyspepsia
Camilleri, M., & Stanghellini, V. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.11 · Cited by 180 · see citing works
Self-citationGastrointestinal Symptoms in Diabetes: Prevalence, Assessment, Pathogenesis, and Management
Du, Y., Rayner, C. K., Jones, K. L., Talley, N. J., & Horowitz, M. (2018) · Diabetes Care · doi:10.2337/dc17-1536 · Cited by 182 · see citing works
Wauters, L. I., Dickman, R. M., Drug, V. L., Mulak, A., Serra, J., Enck, P., Tack, J. F., ESNM FD Consensus Group, Accarino, A. M., Barbara, G., et al. (2021) · United European Gastroenterology Journal · doi:10.1002/ueg2.12061 · Cited by 180 · see citing works
The gut Microbiome in adult and pediatric functional gastrointestinal disorders
Shin, A., Preidis, G. A., Shulman, R., & Kashyap, P. C. (2019) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2018.08.054 · Cited by 163 · see citing works
Prevalence of Hidden Gastroparesis in the Community: The Gastroparesis "Iceberg"
Rey, E., Choung, R. S., Schleck, C. D., Zinsmeister, A. R., Talley, N. J., & Locke, G. R. (2012) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2012.18.1.34 · Cited by 156 · see citing works
A community-based, controlled study of the epidemiology and pathophysiology of dyspepsia
Castillo, E. J., Camilleri, M., Locke, G. R., Burton, D. D., Stephens, D. A., Geno, D. M., & Zinsmeister, A. R. (2004) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00454-9 · Cited by 150 · see citing works
Self-citationRelationship between clinical features and gastric emptying disturbances in diabetes mellitus
Bharucha, A. E., Camilleri, M., Forstrom, L. A., & Zinsmeister, A. R. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03351.x · Cited by 146 · see citing works
Self-citationAssessment of gastric accommodation: overview and evaluation of current methods
Schepper, H. U. D., Cremonini, F., Chitkara, D. K., & Camilleri, M. (2004) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2004.00497.x · Cited by 133 · see citing works
Self-citationMethods for measurement of gastric motility
Szarka, L. A., & Camilleri, M. (2009) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.90467.2008 · Cited by 130 · see citing works
Self-citationGastroparesis: Clinical Update. CME
Park, M. I., & Camilleri, M. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00640.x · Cited by 129 · see citing works
Self-citationColeski, R., Anderson, M., & Hasler, W. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0660-9 · Cited by 119 · see citing works
Applied Principles of Neurogastroenterology: Physiology/Motility Sensation
Kellow, J. E., Azpiroz, F., Delvaux, M. M., Gebhart, G. F., Mertz, H. R., Quigley, E. M. M., & Smout, A. J. P. M. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.08.061 · Cited by 117 · see citing works
Visceral hypersensitivity and impaired accommodation in refractory diabetic gastroparesis
Kumar, A., Attaluri, A., Hashmi, S., Schulze, K. S., & Rao, S. S. C. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01081.x · Cited by 110 · see citing works
Rumination syndrome: pathophysiology, diagnosis, and treatment
Absah, I., Rishi, A. R., Talley, N. J., Katzka, D. A., & Halland, M. (2016) · Neurogastroenterology & Motility · doi:10.1111/nmo.12954 · Cited by 109 · see citing works
Vittal, H., Farrugia, G., Gomez, G., & Pasricha, P. J. (2007) · Nature Clinical Practice Gastroenterology & Hepatology · doi:10.1038/ncpgasthep0838 · Cited by 109 · see citing works
Brun, R., & Kuo, B. (2010) · Therapeutic Advances in Gastroenterology · doi:10.1177/1756283x10362639 · Cited by 105 · see citing works
Gastric Motor Dysfunction in Patients With Functional Gastroduodenal Symptoms
Park, S.-Y., Acosta, A., Camilleri, M., Burton, D., Harmsen, W., Fox, J. C., & Szarka, L. (2017) · American Journal of Gastroenterology · doi:10.1038/ajg.2017.264 · Cited by 87 · see citing works
Self-citationSafety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children
Rodriguez, L., Díaz, J. J., & Nurko, S. (2013) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2012.12.096 · Cited by 98 · see citing works
Diagnosis and Treatment of Rumination Syndrome
Halland, M., Pandolfino, J. E., & Barba, E. (2018) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2018.05.049 · Cited by 98 · see citing works
Manabe, N., Wong, B. S., & Camilleri, M. (2010) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2010.482927 · Cited by 97 · see citing works
Self-citationPeripheral opioid receptor agonists for analgesia: A comprehensive review
Vadivelu, N., Mitra, S., & Hines, R. L. (2011) · Journal of Opioid Management · doi:10.5055/jom.2011.0049 · Cited by 96 · see citing works
Technology Review: Esophageal Impedance Monitoring
Bredenoord, A. J., Tutuian, R. I., Smout, A. J. P. M., & Castell, D. O. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00966.x · Cited by 96 · see citing works
Self-citationAqel, B. A., Scolapio, J. S., Dickson, R. C., Burton, D. D., & Bouras, E. P. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(05)00531-8 · Cited by 94 · see citing works
Gastric Motor and Sensory Functions in Obesity
Park, M. I., & Camilleri, M. (2005) · Obesity Research · doi:10.1038/oby.2005.51 · Cited by 93 · see citing works
Self-citationPredictors of the placebo response in functional dyspepsia
Talley, N. J., Locke, G. R., Lahr, B. D., Zinsmeister, A. R., Cohard, M., D'ELIA, T. V., Tack, J. F., & Earnest, D. L. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.02845.x · Cited by 91 · see citing works
Do Distinct Dyspepsia Subgroups Exist in the Community? A Population-Based Study
Choung, R. S., Locke, G. R., Schleck, C. D., Zinsmeister, A. R., & Talley, N. J. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01381.x · Cited by 88 · see citing works
Gastric sensory and motor dysfunction in adolescents with functional dyspepsia
Chitkara, D. K., Camilleri, M., Zinsmeister, A. R., Burton, D. D., El‐Youssef, M., Freese, D. K., Walker, L. S., & Stephens, D. A. (2005) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2004.11.031 · Cited by 89 · see citing works
Self-citationPlasticity of vagal brainstem circuits in the control of gastric function
Browning, K. N., & Travagli, R. A. (2010) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2010.01592.x · Cited by 88 · see citing works
Antispasmodic Potential of Medicinal Plants: A Comprehensive Review
Rauf, A., Akram, M., Semwal, P., Mujawah, A., Muhammad, N., Riaz, Z., Munir, N., Piotrovsky, D., Vdovina, I. V., Bouyahya, A., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/4889719 · Cited by 84 · see citing works
Relationship Between Control of Glycemia and Gastric Emptying Disturbances in Diabetes Mellitus
Halland, M., & Bharucha, A. E. (2015) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2015.11.021 · Cited by 84 · see citing works
Ford, A., Thabane, M., Collins, S., Moayyedi, P., Garg, A., Clark, W., & Marshall, J. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.01.043 · Cited by 79 · see citing works
Pathophysiology as a basis for understanding symptom complexes and therapeutic targets
Camilleri, M., & Talley, N. J. (2004) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2004.00516.x · Cited by 79 · see citing works
Self-citationFunctional Dyspepsia and Gastroparesis
Camilleri, M. (2016) · Digestive Diseases · doi:10.1159/000445226 · Cited by 77 · see citing works
Self-citationApplication of magnetic resonance imaging to measure fasting and postprandial volumes in humans
Fidler, J. L., Bharucha, A. E., Camilleri, M., Camp, J. J., Burton, D. B., Grimm, R., Riederer, S. J., Robb, R. A., & ZINSMEISTER, A. R. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01194.x · Cited by 75 · see citing works
Self-citationDiagnostic Assessment of Diabetic Gastroparesis
Shin, A., & Camilleri, M. (2013) · Diabetes · doi:10.2337/db12-1706 · Cited by 73 · see citing works
Self-citationTests of Gastric Neuromuscular Function
Parkman, H. P., & Jones, M. P. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.02.039 · Cited by 72 · see citing works
Saito, Y., Suzuki, H., Tsugawa, H., Suzuki, S., Matsuzaki, J., Hirata, K., & Hibi∥, T. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.08.044 · Cited by 66 · see citing works
Rapid Gastric Emptying Is More Common than Gastroparesis in Patients With Autonomic Dysfunction
Lawal, A., Barboi, A., Krasnow, A., Hellman, R., Jaradeh, S., & Massey, B. T. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00946.x · Cited by 66 · see citing works
Jeong, I. D., Camilleri, M., Shin, A., Iturrino, J., Boldingh, A., Busciglio, I. A., Burton, D. D., Ryks, M. D., Rhoten, D. L., & Zinsmeister, A. R. (2012) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2012.05040.x · Cited by 65 · see citing works
Self-citationRecent insights into digestive motility in functional dyspepsia
Mizuta, Y., Shikuwa, S., Isomoto, H., Mishima, R., Akazawa, Y., Masuda, J.-I., Omagari, K., Takeshima, F., & Kohno, S. (2006) · Journal of Gastroenterology · doi:10.1007/s00535-006-1966-z · Cited by 64 · see citing works
Chedid, V., Brandler, J., Vijayvargiya, P., Park, S.-Y., Szarka, L. A., & Camilleri, M. (2019) · American Journal of Gastroenterology · doi:10.1038/s41395-018-0234-1 · Cited by 65 · see citing works
Self-citationDelgado-Aros, S., Camilleri, M., Castillo, E. J., Cremonini, F., Stephens, D. A., Ferber, I., Baxter, K. L., Burton, D. D., & Zinsmeister, A. R. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(05)00285-5 · Cited by 63 · see citing works
Self-citationVella, A. V., Bock, G., Giesler, P. D., Burton, D. B., Serra, D. B., Ligueros‐Saylan, M., Deacon, C. F., Foley, J. E., Rizza, R. A., & Camilleri, M. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03235.x · Cited by 62 · see citing works
Self-citationGastrointestinal Motility, Part 1: Esophageal Transit and Gastric Emptying
Maurer, A. (2015) · Journal of Nuclear Medicine · doi:10.2967/jnumed.112.114314 · Cited by 54 · see citing works
Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals
Camilleri, M., & Linden, D. (2016) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2016.04.003 · Cited by 55 · see citing works
Self-citationBouras, E. P., Talley, N. J., Camilleri, M., Burton, D. D., Heckman, M. G., Crook, J. E., & Richelson, E. (2008) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2008.02021.x · Cited by 60 · see citing works
Self-citationBreen, M. A., Camilleri, M., Burton, D. D., & Zinsmeister, A. R. (2011) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2010.01660.x · Cited by 58 · see citing works
Self-citationWauters, L. I., Dickman, R. M., Drug, V. L., Mulak, A., Serra, J., Enck, P., Tack, J. F., ESNM FD Consensus Group, Accarino, A. M., Barbara, G., et al. (2021) · Neurogastroenterology & Motility · doi:10.1111/nmo.14238 · Cited by 58 · see citing works
Delgado-Aros, S., & Camilleri, M. (2005) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000156114.22598.1b · Cited by 57 · see citing works
Self-citationVagal afferent fibres determine the oxytocin‐induced modulation of gastric tone
Holmes, G. M., Browning, K. N., Babic, T., Fortna, S. R., Coleman, F. H., & Travagli, R. A. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2013.253732 · Cited by 56 · see citing works
Kolar, G. J., Camilleri, M., Burton, D. D., Nadeau, A. M., & Zinsmeister, A. R. (2013) · Neurogastroenterology & Motility · doi:10.1111/nmo.12242 · Cited by 56 · see citing works
Self-citationHalawi, H., Camilleri, M., Acosta, A. J., Vázquez‐Roque, M. I., Oduyebo, I., Burton, D. D., Busciglio, I. A., & Zinsmeister, A. R. (2017) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00190.2017 · Cited by 56 · see citing works
Self-citationAGA Clinical Practice Guideline on Management of Gastroparesis
Staller, K. D., Parkman, H. P., Greer, K. B., Leiman, D. A., Zhou, M. J., Singh, S., Camilleri, M., & Altayar, O. (2025) · Gastroenterology · doi:10.1053/j.gastro.2025.08.004 · Cited by 61 · see citing works
Self-citationJacob, D. A., Busciglio, I., Burton, D., Halawi, H., Oduyebo, I., Rhoten, D., Ryks, M., Harmsen, W., & Camilleri, M. (2017) · American Journal of Physiology - Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00197.2017 · Cited by 44 · see citing works
Self-citationVijayvargiya, P., Iturrino, J., Camilleri, M., Shin, A., Vázquez‐Roque, M. I., Katzka, D. A., Snuggerud, J. R., & Seime, R. J. (2014) · United European Gastroenterology Journal · doi:10.1177/2050640613518774 · Cited by 54 · see citing works
Self-citationTominaga, K., & Arakawa, T. (2013) · Journal of Gastroenterology · doi:10.1007/s00535-013-0788-z · Cited by 54 · see citing works
Aerophagia in adults: a comparison with functional dyspepsia
Chitkara, D. K., Bredenoord, A. J., Rucker, M. J., & Talley, N. J. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02651.x · Cited by 54 · see citing works
Self-citationKindt, S., Coulie, B. J., Wajs, E., Janssens, J., & Tack, J. F. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01092.x · Cited by 53 · see citing works
Gonenne, J., Castillo, E. J., Camilleri, M., Burton, D. D., Thomforde, G. M., Baxter, K. L., & Zinsmeister, A. R. (2004) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2004.00588.x · Cited by 53 · see citing works
Self-citationEusebi, L., Ratnakumaran, R., Bazzoli, F., & Ford, A. (2018) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2017.07.041 · Cited by 44 · see citing works
Gastric motor disturbances in patients with idiopathic rapid gastric emptying
Bharucha, A. E., Manduca, A., Lake, D. S., Fidler, J. L., Edwards, P. K., Grimm, R. C., Zinsmeister, A. R., & Riederer, S. J. (2011) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2011.01710.x · Cited by 50 · see citing works
Mimidis, K., & Tack, J. F. (2008) · Digestive Diseases · doi:10.1159/000121346 · Cited by 49 · see citing works
Gastric accommodation: Physiology, diagnostic modalities, clinical relevance, and therapies
Febo‐Rodriguez, L., Chumpitazi, B. P., Sher, A. C., & Shulman, R. J. (2021) · Neurogastroenterology & Motility · doi:10.1111/nmo.14213 · Cited by 46 · see citing works
Early satiety in cancer patients: a common and important but underrecognized symptom
Davis, M. P., Walsh, D., Lagman, R. L., & Yavuzşen, T. (2006) · Supportive Care in Cancer · doi:10.1007/s00520-005-0015-4 · Cited by 45 · see citing works
Kindt, S., Dubois, D., Oudenhove, L. V., Caenepeel, P., Arts, J., Bisschops, R., & Tack, J. F. (2009) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2009.01374.x · Cited by 45 · see citing works
Maurer, A. H. (2012) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2011.10.001 · Cited by 45 · see citing works
Gwee, K., Lee, Y. Y., Suzuki, H., Ghoshal, U. C., Holtmann, G., Bai, T., Barbara, G., Chen, M., Chua, A. S. B., Gibson, P. R., et al. (2022) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.16046 · Cited by 45 · see citing works
Current Medical Treatments of Dyspepsia and Irritable Bowel Syndrome
Camilleri, M., & Tack, J. F. (2010) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2010.08.005 · Cited by 44 · see citing works
Self-citationDysaccommodation of the stomach: therapeutic nirvana?
Bisschops, R., & Tack, J. F. (2006) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00863.x · Cited by 43 · see citing works
Gastrointestinal complications of fundoplication
Connor, F. L. (2005) · Current Gastroenterology Reports · doi:10.1007/s11894-005-0038-5 · Cited by 43 · see citing works
Wong, G. K., Shulman, R. J., & Chumpitazi, B. P. (2015) · Neurogastroenterology & Motility · doi:10.1111/nmo.12499 · Cited by 42 · see citing works
Influence of acid suppressants on gastric emptying: Cross‐over analysis in healthy volunteers
Takahashi, Y., Amano, Y., Yuki, T., Ose, T., Miyake, T., Kushiyama, Y., Satō, S., Ishihara, S., & Kinoshita, Y. (2006) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04270.x · Cited by 40 · see citing works
Ford, A. C., Talley, N. J., Walker, M. M., & Jones, M. (2014) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12903 · Cited by 39 · see citing works
Novel mechanisms in functional dyspepsia
Choung, R. S. (2006) · World Journal of Gastroenterology · doi:10.3748/wjg.v12.i5.673 · Cited by 39 · see citing works
Selected Interventions in Nuclear Medicine: Gastrointestinal Motor Functions
Odunsi, S. T., & Camilleri, M. (2009) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2008.11.002 · Cited by 38 · see citing works
Self-citationComparison of gastric volumes in response to isocaloric liquid and mixed meals in humans
Schepper, H. U. D., Camilleri, M., Cremonini, F., Foxx–Orenstein, A. E., & Burton, D. D. (2004) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2004.00533.x · Cited by 38 · see citing works
Self-citationGastroparesis and Dumping Syndrome: Current Concepts and Management
Vavricka, S. R., & Greuter, T. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8081127 · Cited by 37 · see citing works
van den Elzen, B. D. J., Bennink, R. J., Holman, R., Tytgat, G. N. J., & Boeckxstaens, G. E. (2007) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2007.00971.x · Cited by 37 · see citing works
Broeders, B., Carbone, F., Balsiger, L. M., Schol, J., Raymenants, K., Huang, I., Verheyden, A., Vanuytsel, T., & Tack, J. F. (2023) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17414 · Cited by 38 · see citing works
Gastric motor and sensory function
Tack, J. F. (2009) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e328331b5ad · Cited by 36 · see citing works
Ling, W., Li, Y., Jiang, W., Sui, Y., & Zhao, H. (2015) · Medicine · doi:10.1097/md.0000000000001111 · Cited by 35 · see citing works
Rosen, J. M. (2014) · World Journal of Gastrointestinal Pharmacology and Therapeutics · doi:10.4292/wjgpt.v5.i3.122 · Cited by 35 · see citing works
Gastric compliance in bulimia nervosa
Zimmerli, E. J., Walsh, B. T., Guss, J. L., Devlin, M. J., & Kissileff, H. R. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.11.010 · Cited by 35 · see citing works
Bratten, J. R., & Jones, M. P. (2006) · Digestive Diseases · doi:10.1159/000092878 · Cited by 34 · see citing works
Effect of Vagus Nerve Integrity on Short and Long-Term Efficacy of Antireflux Surgery
van Rijn, S., Rinsma, N. F., Lindeboom, M. Y. A., Ringers, J., Gooszen, H. G., van Rijn, P. J. J., Veenendaal, R. A., Conchillo, J. M., Bouvy, N. D., & Masclee, A. (2016) · The American Journal of Gastroenterology · doi:10.1038/ajg.2016.42 · Cited by 34 · see citing works
Functional Dyspepsia: Mechanisms of Symptom Generation and Appropriate Management of Patients
Camilleri, M. (2007) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2007.07.001 · Cited by 33 · see citing works
Self-citationCamilleri, M. (2023) · Gut · doi:10.1136/gutjnl-2023-330542 · Cited by 25 · see citing works
Self-citationPharmacological agents currently in clinical trials for disorders in neurogastroenterology
Camilleri, M. (2013) · Journal of Clinical Investigation · doi:10.1172/jci70837 · Cited by 32 · see citing works
Self-citation
- Authors
- Bredenoord, A. J., Chial, H. J., Camilleri, M., Mullan, B. P., & Murray, J. A.
- Affiliations
- Mayo Clinic (US)
- Corresponding author
- Camilleri, Michael
- Venue
- Clinical Gastroenterology and Hepatology
- Publisher
- Elsevier BV
- Published
- 2003-07
- Volume
- 1
- Issue
- 4
- Pages
- 264-272
- ISSN
- 1542-3565 (ISSN-L)
- OpenAlex
- W2159492794
- Cited by
- 243
- References
- 44
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 7 · 2023: 7 · 2022: 6 · 2021: 13 · 2020: 12 · 2019: 15 · 2018: 11 · 2017: 7 · 2016: 9 · 2015: 10 · 2014: 8 · 2013: 11 · 2012: 10
- FWCI
- 14.74
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Gastroenterology and Hepatology (publishedVersion)
- PubMed (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (K24 DK02638, R01 DK-54681, R01 DK57982, K24DK002638, R01DK054681)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
- Keywords
- gastric accommodation, gastric emptying, functional dyspepsia, rumination syndrome, gastric emptying scintigraphy, upper gastrointestinal symptoms
- MeSH terms
- Adolescent, Adult, Aged, Diabetes Mellitus, Dyspepsia, Fasting, Female, Gastric Emptying, Gastroesophageal Reflux, Gastrointestinal Motility, Humans, Male, Manometry, Middle Aged, Minnesota, Recurrence, Tomography, X-Ray Computed, Cohort Studies, Tomography, Emission-Computed, Single-Photon, Endoscopy, Gastrointestinal, Treatment Outcome, Ultrasonography, Interventional, Fundoplication, Postprandial Period, Upper Gastrointestinal Tract
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
