The proteasome in brain aging

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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Cyclin is degraded by the ubiquitin pathway

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Aggresomes: A Cellular Response to Misfolded Proteins

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The 26S Proteasome: A Molecular Machine Designed for Controlled Proteolysis

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.Preprint

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Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences

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NF-κB in neuronal plasticity and neurodegenerative disorders

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Degradation of oxidized proteins by the 20S proteasome

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Degradation of oxidized proteins in mammalian cells

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Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

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Tau‐inclusion body formation in oligodendroglia: the role of stress proteins and proteasome inhibition

Richter‐Landsberg, C., & Bauer, N. G. (2004) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2004.07.003 · Cited by 49

α-Synuclein Promotes the Recruitment of Tau to Protein Inclusions in Oligodendroglial Cells: Effects of Oxidative and Proteolytic Stress

Riedel, M. J., Goldbaum, O., & Richter‐Landsberg, C. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-009-9190-y · Cited by 48

The Expanding Universe of Neurotrophic Factors: Therapeutic Potential in Aging and Age-Associated Disorders

Lanni, C., Stanga, S., Racchi, M., & Govoni, S. M. (2010) · Current Pharmaceutical Design · doi:10.2174/138161210790883741 · Cited by 50

Alterations of cerebral cortex and hippocampal proteasome subunit expression and function in a traumatic brain injury rat model

Yao, X.-L., Liu, J., & McCabe, J. T. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04970.x · Cited by 47

Linkage Between the Proteasome Pathway and Neurodegenerative Diseases and Aging

Vigouroux, S., Briand, M., & Briand, Y. (2004) · Molecular Neurobiology · doi:10.1385/mn:30:2:201 · Cited by 43

Insulin-like growth factor-I mediates neuroprotection in proteasome inhibition-induced cytotoxicity in SH-SY5Y cells

Cheng, B., Maffi, S. K., Martinez, A. A., Acosta, Y. P. V., Morales, L. D., & Roberts, J. L. (2011) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2011.04.002 · Cited by 43

Aging attenuates redox adaptive homeostasis and proteostasis in female mice exposed to traffic-derived nanoparticles (‘vehicular smog’)

Pomatto, L. C. D., Cline, M., Woodward, N. C., Pakbin, P., Sioutas, C., Morgan, T. E., Finch, C. E., Forman, H. J., & Davies, K. J. A. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.04.574 · Cited by 42

Ferritin oxidation and proteasomal degradation: Protection by antioxidants

Voß, P., Horáková, Ľ., Jakstadt, M., Kiekebusch, D., & Grune, T. (2006) · Free Radical Research · doi:10.1080/10715760500419357 · Cited by 41

Translational control in aging and neurodegeneration

Skariah, G., & Todd, P. K. (2020) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1628 · Cited by 42

Oxidative Stress and Protein Quality Control Systems in the Aged Canine Brain as a Model for Human Neurodegenerative Disorders

Romanucci, M., & Salda, L. D. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/940131 · Cited by 43

Interaction of PrP with NRAGE, a protein involved in neuronal apoptosis

Bragason, B. Þ., & Pálsdóttir, Á. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.02.013 · Cited by 39

Regulation of the Proteasome: Evaluating the Lung Proteasome as a New Therapeutic Target

Meiners, S., Kammerl, I. E., Semren, N., & Caniard, A. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2013.5798 · Cited by 40

Coordination between proteasome impairment and caspase activation leading to TAU pathology: neuroprotection by cAMP

Metcalfe, M., Huang, Q., & Figueiredo‐Pereira, M. E. (2012) · Cell Death and Disease · doi:10.1038/cddis.2012.70 · Cited by 38

Dopamine and Aging: Intersecting Facets

Rollo, C. D. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9858-7 · Cited by 37

Hyperactivation of the proteasome in Caenorhabditis elegans protects against proteotoxic stress and extends lifespan

Anderson, R. T., Bradley, T. A., & Smith, D. M. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102415 · Cited by 39

Altered ubiquitin-proteasome system leads to neuronal cell death in a spontaneous obese rat model

Reddy, S. S., Karnam, S., Reddy, V., Raghu, G., Suryanarayana, P., Giridharan, N. V., & Reddy, G. B. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.06.005 · Cited by 37

Prion protein is required for tumor necrosis factor α (TNFα)-triggered nuclear factor κB (NF-κB) signaling and cytokine production

Wu, G.-R., Mu, T.-C., Gao, Z.-X., Wang, J., Sy, M., & Li, C. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.787283 · Cited by 37

Comparison of rat liver and brain proteasomes for oxidative stress-induced inactivation: Influence of ageing and dietary restriction

Dasuri, K., Nguyen, A., Zhang, L., Fernandez-Kim, O. S., Bruce‐Keller, A. J., Blalock, B., de Cabo, R., & Keller, J. N. (2008) · Free Radical Research · doi:10.1080/10715760802534812 · Cited by 36

The expression of tubulin polymerization promoting protein TPPP/p25α is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress

Goldbaum, O., Jensen, P. H., & Richter‐Landsberg, C. (2008) · Glia · doi:10.1002/glia.20720 · Cited by 36

The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease

McNaught, K. S. P., JnoBaptiste, R., Jackson, T., & Jengelley, T. (2009) · Synapse · doi:10.1002/syn.20719 · Cited by 37

Proteasome or calpain inhibition does not alter cellular tau levels in neuroblastoma cells or primary neurons

Brown, M. R., Bondada, V., Keller, J. N., Thorpe, J. A., & Geddes, J. W. (2005) · Journal of Alzheimer s Disease · doi:10.3233/jad-2005-7103 · Cited by 35

RNA interference toward UMP1 induces proteasome inhibition in Saccharomyces cerevisiae: evidence for protein oxidation and autophagic cell death

Chen, Q., Ding, Q., Thorpe, J. A., Dohmen, R. J., & Keller, J. N. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.10.019 · Cited by 35

Degradation of Functional Triose Phosphate Isomerase Protein UnderliessugarkillPathology

Seigle, J. L., Celotto, A. M., & Palladino, M. J. (2008) · Genetics · doi:10.1534/genetics.108.087551 · Cited by 35

The neuronal ubiquitin-proteasome system: Murine models and their neurological phenotype

van Tijn, P., Hol, E. M., van Leeuwen, F. W., & Fischer, D. F. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.03.001 · Cited by 35

Neocortex and Allocortex Respond Differentially to Cellular Stress In Vitro and Aging In Vivo

Posimo, J. M., Titler, A. M., Choi, H. J. H., Unnithan, A. S., & Leak, R. K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058596 · Cited by 32

Impact of aging on heat shock protein expression in the substantia nigra and striatum of the female rat

Gleixner, A. M., Pulugulla, S. H., Pant, D. B., Posimo, J. M., Crum, T. S., & Leak, R. K. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-1852-6 · Cited by 33

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Upadhyay, A., Amanullah, A., Chhangani, D., Mishra, R., & Mishra, A. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.07.009 · Cited by 33

Altered unfolded protein response and proteasome impairment in pseudoexfoliation pathogenesis

Hayat, B., Padhy, B., Mohanty, P. P., & Alone, D. P. (2019) · Experimental Eye Research · doi:10.1016/j.exer.2019.02.004 · Cited by 32

Dihydroquinazolines enhance 20S proteasome activity and induce degradation of α-synuclein, an intrinsically disordered protein associated with neurodegeneration

Fiolek, T. J., Magyar, C. L., Wall, T. J., Davies, S. B., Campbell, M. V., Savich, C. J., Tepe, J. J., & Mosey, R. A. (2021) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2021.127821 · Cited by 32

Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin-proteasome system in PC12D cells

Kawahata, I., Tokuoka, H., Parvez, H., & Ichinose, H. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0304-z · Cited by 31

Aβ42-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for protective crosstalk between protein clearance pathways

Farizatto, K. L. G., Ikonne, U. S., de Almeida, M. F., Ferrari, M., & Bahr, B. A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0182895 · Cited by 33

Longitudinal Magnetic Resonance Imaging of Sildenafil Treatment of Embolic Stroke in Aged Rats

Ding, G., Jiang, Q., Li, L., Zhang, L., Zhang, Z., Lü, M., Li, Q., Gu, S., Ewing, J. R., & Chopp, M. (2011) · Stroke · doi:10.1161/strokeaha.111.622092 · Cited by 31

The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline

Castonguay, D., Dufort‐Gervais, J., Ménard, C., Chatterjee, M., Quirion, R., Bontempi, B., Schneider, J. S., Arnsten, A. F. T., Nairn, A. C., Norris, C. M., et al. (2018) · Current Biology · doi:10.1016/j.cub.2018.02.047 · Cited by 30

Prions and the proteasome

Deriziotis, P., & Tabrizi, S. J. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2008.06.011 · Cited by 29

Mechanisms and Biological Consequences of Peroxynitrite-Dependent Protein Oxidation and Nitration

Trujillo, M., Álvarez, B., Souza, J. M., Romero, N., Castro, L., Thomson, L., & Radí, R. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-373866-0.00003-4 · Cited by 29

Oxidized SOD1 alters proteasome activities in vitro and in the cortex of SOD1 overexpressing mice

LePecheur, M., Bourdon, E., Paly, E., Farout, L., Friguet, B., & London, J. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.05.048 · Cited by 28

Analysis of gene expression in neural cells subject to chronic proteasome inhibition

Ding, Q., Bruce‐Keller, A. J., Chen, Q., & Keller, J. N. (2003) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.10.025 · Cited by 30

Organelle aging: Lessons from model organisms

Bouska, M. J., Huang, K., Kang, P., & Bai, H. (2019) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2019.03.011 · Cited by 27

Normal ageing of the brain: Histological and biological aspects

Teissier, T., Boulanger, É., & Deramecourt, V. (2020) · Revue Neurologique · doi:10.1016/j.neurol.2020.03.017 · Cited by 37

Effect of proteasome inhibition by MG‐132 on HSP27 oligomerization, phosphorylation, and aggresome formation in the OLN‐93 oligodendroglia cell line

Bolhuis, S., & Richter‐Landsberg, C. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06600.x · Cited by 28

Persistent mitochondrial dysfunction and oxidative stress hinder neuronal cell recovery from reversible proteasome inhibition

Papa, L., & Rockwell, P. (2008) · APOPTOSIS · doi:10.1007/s10495-008-0182-0 · Cited by 26

Cytosolic prion protein induces apoptosis in human neuronal cell SH-SY5Y via mitochondrial disruption pathway

Wang, X., Dong, C., Shi, Q., Shi, S., Wang, G., Lei, Y., Xu, K., An, R., Chen, J., Jiang, H.-Y., et al. (2009) · BMB Reports · doi:10.5483/bmbrep.2009.42.7.444 · Cited by 26

The involvement of glycogen synthase kinase‐3 and protein phosphatase‐2A in lactacystin‐induced tau accumulation

Ren, Q., Liao, X., Wang, X., Qu, Z.-S., & Wang, J. (2006) · FEBS Letters · doi:10.1016/j.febslet.2006.03.073 · Cited by 26

Modelling the Role of UCH-L1 on Protein Aggregation in Age-Related Neurodegeneration

Proctor, C. J., Tangeman, P. J., & Ardley, H. C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013175 · Cited by 26

Up‐regulation of endoplasmic reticulum stress‐related genes during the early phase of treatment of cultured cortical neurons by the proteasomal inhibitor lactacystin

Choy, M. S., Chen, M. J., Manikandan, J., Peng, Z. F., Jenner, A. M., Melendez, A. J., & Cheung, N. S. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22359 · Cited by 25

Inactivation of the 20S proteasome maturase, Ump1p, leads to the instability of mtDNA in Saccharomyces cerevisiae

Malc, E. P., Dzierzbicki, P., Kaniak, A., Skoneczna, A., & Cieśla, Z. (2009) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2009.05.008 · Cited by 25

β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling

Liu, W., Sun, F.-X., Wan, M., Jiang, F., Xiangyu, B. O., Lin, L., Tang, H., & Xu, S. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00969 · Cited by 24

Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival

Benvegnù, S., Mateo, M. I., Palomer, E., Jurado‐Arjona, J., & Dotti, C. G. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.04.005 · Cited by 24

Quantitative Proteomics Reveals Extensive Changes in the Ubiquitinome after Perturbation of the Proteasome by Targeted dsRNA-Mediated Subunit Knockdown in Drosophila

Sap, K. A., Bezstarosti, K., Dekkers, D. H. W., Voets, O., & Demmers, J. (2017) · Journal of Proteome Research · doi:10.1021/acs.jproteome.7b00156 · Cited by 24

Horizons in Human Aging Neuroscience: From Normal Neural Aging to Mental (Fr)Agility

Ridderinkhof, K. R., & Krugers, H. J. (2022) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2022.815759 · Cited by 25

Decoupling of mRNA and Protein Expression in Aging Brains Reveals the Age-Dependent Adaptation of Specific Gene Subsets

Khatir, I., Brunet, M. A., Meller, A., Amiot, F., Patel, T., Lapointe, X., Avila Lopez, J., Guilloy, N., Castonguay, A., Husain, M. A., et al. (2023) · Cells · doi:10.3390/cells12040615 · Cited by 22

Proteolytic Dysfunction in Neurodegenerative Disorders

McNaught, K. S. P. (2004) · International review of neurobiology · doi:10.1016/s0074-7742(04)62003-4 · Cited by 24

Defective Retrotranslocation Causes Loss of Anti-Bax Function in Human Familial Prion Protein Mutants

Jodoin, J., Laroche‐Pierre, S., Goodyer, C. G., & LeBlanc, A. C. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0957-07.2007 · Cited by 22

Circulating proteasome activity following mild head injury in children

Tylicka, M., Matuszczak, E., Dębek, W., Hermanowicz, A., & Ostrowska, H. (2014) · Child s Nervous System · doi:10.1007/s00381-014-2409-4 · Cited by 21

Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders

Kelley, C. M., Ginsberg, S. D., Liang, W. S., Counts, S., & Mufson, E. J. (2022) · Brain Communications · doi:10.1093/braincomms/fcac162 · Cited by 23

Hrd1 Facilitates Tau Degradation and Promotes Neuron Survival

Shen, Y., Sun, A. M., Fang, S., Feng, L., Li, Q., Hou, H., Liu, C. L., Wang, H. P., Shen, J., Luo, J., et al. (2012) · Current Molecular Medicine · doi:10.2174/156652412798889009 · Cited by 22

Activation of PERK kinase in neural cells by proteasome inhibitor treatment

Zhang, L., Ebenezer, P. J., Dasuri, K., Bruce‐Keller, A. J., Fernandez‐Kim, S. O., Liu, Y., & Keller, J. N. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06448.x · Cited by 20

The Amyloid Hypothesis and the clearance and degradation of Alzheimer's β-peptide

LeVine, H. (2004) · Journal of Alzheimer s Disease · doi:10.3233/jad-2004-6311 · Cited by 20

Decreased Proteasomal Function Induces Neuronal Loss and Memory Impairment

Tomaru, U., Ito, T., Ohmura, Y., Higashikawa, K., Miyajima, S., Tomatsu, R., Higashi, T., Ishizu, A., Kuge, Y., Yoshioka, M., et al. (2020) · American Journal Of Pathology · doi:10.1016/j.ajpath.2020.10.004 · Cited by 20

Functional Proteomics Related to Energy Metabolism of Synaptosomes from Different Neuronal Systems of Rat Hippocampus during Aging

Villa, R. F., Ferrari, F., & Gorini, A. (2013) · Journal of Proteome Research · doi:10.1021/pr400834g · Cited by 18

Heat shock protein responses to aging and proteotoxicity in the olfactory bulb

Crum, T. S., Gleixner, A. M., Posimo, J. M., Mason, D. M., Broeren, M. T., Heinemann, S. D., Wipf, P., Brodsky, J. L., & Leak, R. K. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13041 · Cited by 18

Molecular networks perturbed in a developmental animal model of brain injury

Kisby, G., Standley, M. S., Lu, X., O'Malley, J. P., Lin, B., Muniz, J. F., Luo, N. L., Pattee, P., Back, S. A., & Nagalla, S. R. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2004.11.014 · Cited by 18

Lifestyle strategies to promote proteostasis and reduce the risk of Alzheimer’s disease and other proteinopathies

de Almeida, M. F., Farizatto, K. L. G., Almeida, R. S., & Bahr, B. A. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102162 · Cited by 17

Loss of an individual proteasome subunit alters motor function but not cognitive function or ambulation in mice

Martin, S. K., Gee, J. R., Bruce‐Keller, A. J., & Keller, J. N. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2003.10.085 · Cited by 17

Phosphorylation of the 19S regulatory particle ATPase subunit, Rpt6, modifies susceptibility to proteotoxic stress and protein aggregation

Marquez-Lona, E. M., Torres-Machorro, A. L., Gonzales, F. R., Pillus, L., & Patrick, G. N. (2017) · PLOS ONE · doi:10.1371/journal.pone.0179893 · Cited by 17

Low levels of mutant ubiquitin are degraded by the proteasome in vivo

van Tijn, P., Verhage, M. C., Hobo, B., van Leeuwen, F. W., & Fischer, D. F. (2010) · Journal of Neuroscience Research · doi:10.1002/jnr.22396 · Cited by 16

Autophagy Coupling Interplay: Can Improve Cellular Repair and Aging?

Chhangani, D., Chinchwadkar, S., & Mishra, A. (2014) · Molecular Neurobiology · doi:10.1007/s12035-013-8599-z · Cited by 16

2‐Benzazepine Nitrones Protect Dopaminergic Neurons against 6‐Hydroxydopamine‐Induced Oxidative Toxicity

Soto‐Otero, R., Méndez‐Álvarez, E., Sánchez‐Iglesias, S., Labandeira-García, J. L., Rodríguez‐Pallares, J., Zubkov, F. I., Zaytsev, V. P., Voskressensky, L. G., Varlamov, A. V., de Candia, M., et al. (2012) · Archiv der Pharmazie · doi:10.1002/ardp.201200007 · Cited by 16

Road to Alzheimer’s Disease: The Pathomechanism Underlying

Anand, R., Kaushal, A., Wani, W. Y., & Gill, K. D. (2011) · Pathobiology · doi:10.1159/000332218 · Cited by 16

UVB-mediated down-regulation of proteasome in cultured human primary pterygium fibroblasts

Aletras, A. J., Τριλίβας, Ι., Christopoulou, M. E., Drakouli, S., Georgakopoulos, C. D., & Pharmakakis, N. M. (2018) · BMC Ophthalmology · doi:10.1186/s12886-018-0987-8 · Cited by 14

Activation of Autophagy by Rapamycin Does Not Protect Oligodendrocytes Against Protein Aggregate Formation and Cell Death Induced by Proteasomal Inhibition

Noack, M., & Richter‐Landsberg, C. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0380-x · Cited by 14

Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells

Ovchinnikov, D. A., & Wolvetang, E. J. (2014) · Journal of Clinical Medicine · doi:10.3390/jcm3041357 · Cited by 13

Proteasome inhibition modulates kinase activation in neural cells: Relevence to ubiquitination, ribosomes, and survival

Zhang, L., Ebenezer, P. J., Dasuri, K., Bruce‐Keller, A. J., Liu, Y., & Keller, J. N. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22147 · Cited by 13

Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice

Lv, Y.-Q., Meng, B., Dong, H., Jing, T., Wu, N., Yang, Y., Huang, L., Moses, R. E., O’Malley, B. W., Mei, B., et al. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.285 · Cited by 13

Decreased proteasomal cleavage at nitrotyrosine sites in proteins and peptides

Ott, C., Tomasina, F., Campolo, N., Bartesaghi, S., Mastrogiovanni, M., Leyva, A., Batthyány, C., Meinl, W., Grune, T., & Radí, R. (2021) · Redox Biology · doi:10.1016/j.redox.2021.102106 · Cited by 13

Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by BDNF

Cases‐Cunillera, S., Saavedra, A., Tyebji, S., Giralt, A., Alberch, J., & Pérez‐Navarro, E. (2017) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2017.11.003 · Cited by 12

Compromised proteasome degradation elevates neuronal nitric oxide synthase levels and induces apoptotic cell death

Lam, P. Y., & Cadenas, E. (2008) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2008.07.022 · Cited by 11

Spatio-temporal correlates of gene expression and cortical morphology across lifespan and aging

Qiu, A., Zhang, H., Kennedy, B. K., & Lee, A. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117426 · Cited by 10

Proteomic analysis of the amyloid precursor protein fragment C99: expression in yeast

Sparvero, L. J., Patz, S., Brodsky, J. L., & Coughlan, C. M. (2007) · Analytical Biochemistry · doi:10.1016/j.ab.2007.07.033 · Cited by 11

Upregulation of PSMB8 and cathepsins in the human brains of dementia with Lewy bodies

Ding, Q., & Zhu, H. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.05.022 · Cited by 10

α‐Secretase cleaved amyloid precursor protein ( APP ) accumulates in cholinergic dystrophic neurites in normal, aged hippocampus

Yoon, S. ‐., Choi, J. ‐., Cho, M., Yang, K., Ha, H., Chung, I. J., Cho, G. S., & Kim, D. H. (2013) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12032 · Cited by 9

Heat Shock Proteins and Protein Quality Control in Alzheimer’s Disease

van Leeuwen, F. W., & Kampinga, H. H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811304-2.00010-9 · Cited by 9

Energy Metabolism of Synaptosomes from Different Neuronal Systems of Rat Cerebellum During Aging: A Functional Proteomic Characterization

Ferrari, F., Gorini, A., & Villa, R. F. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1482-0 · Cited by 8

Ageing and the Autonomic Nervous System

Takla, M., Saadeh, K., Tse, G., Huang, C. L.-H., & Jeevaratnam, K. (2023) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-26576-1_10 · Cited by 8

Translational effects and coding potential of an upstream open reading frame associated with DOPA Responsive Dystonia

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