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Glycaemic variability in diabetes: clinical and therapeutic implications

Ceriello, Antonio, Monnier, Louis, Owens, David·2019·The Lancet Diabetes & Endocrinology

DOI 10.1016/s2213-8587(18)30136-0

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Abstract

Glycaemic variability is an integral component of glucose homoeostasis. Although it has not yet been definitively confirmed as an independent risk factor for diabetes complications, glycaemic variability can represent the presence of excess glycaemic excursions and, consequently, the risk of hyperglycaemia or hypoglycaemia. Glycaemic variability is currently defined by a large and increasing number of metrics, representing either short-term (within-day and between-day variability) or long-term glycaemic variability, which is usually based on serial measurements of HbA 1c or other measures of glycaemia over a longer period of time. In this Review, we discuss recent evidence examining the association between glycaemic variability and diabetes-related complications, as well as non-pharmacological and pharmacological strategies currently available to address this challenging aspect of diabetes management.

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Effects of Intensive Glucose Lowering in Type 2 Diabetes
(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0802743 · Cited by 7,888
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
Monnier, L., Mas, E., Ginet, C., Michel, F., Villon, L., Cristol, J.-P., & Colette, C. (2006) · JAMA · doi:10.1001/jama.295.14.1681 · Cited by 2,444
Self-citation
International consensus on use of continuous glucose monitoring
Danne, T., Nimri, R., Battelino, T., Bergenstal, R. M., Close, K. L., DeVries, J. H., Garg, S., Heinemann, L., Hirsch, I., Amiel, S. A., et al. (2017) · Diabetes Care · doi:10.2337/dc17-1600 · Cited by 2,069
9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee (2022) · Diabetes Care · doi:10.2337/dc22-s009 · Cited by 1,555
6. Glycemic Targets: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee (2022) · Diabetes Care · doi:10.2337/dc22-s006 · Cited by 1,403
Oscillating Glucose Is More Deleterious to Endothelial Function and Oxidative Stress Than Mean Glucose in Normal and Type 2 Diabetic Patients
Ceriello, A., Esposito, K., Piconi, L., Ihnat, M. A., Thorpe, J. E., Testa, R., Boemi, M., & Giugliano, D. (2008) · Diabetes · doi:10.2337/db08-0063 · Cited by 1,310
Self-citation
Effect of Continuous Glucose Monitoring on Glycemic Control in Adults With Type 1 Diabetes Using Insulin Injections: The DIAMOND Randomized Clinical Trial
Beck, R. W., Riddlesworth, T., Ruedy, K., Ahmann, A., Bergenstal, R., Haller, S., Kollman, C., Kruger, D., McGill, J. B., Polonsky, W., et al. (2017) · JAMA · doi:10.1001/jama.2016.19975 · Cited by 1,185
Continuous Glucose Monitoring in Pregnant Women with Type 1 Diabetes (CONCEPTT): a multicentre international randomised controlled trial
Feig, D. S., Donovan, L. E., Corcoy, R., Murphy, K. E., Amiel, S. A., Hunt, K. F., Asztalos, E., Barrett, J. F. R., Sanchez, J. J., de Leiva, A., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32400-5 · Cited by 803
Intermittent High Glucose Enhances Apoptosis Related to Oxidative Stress in Human Umbilical Vein Endothelial Cells
Quagliaro, L., Piconi, L., Assaloni, R., Martinelli, L., Motz, E., & Ceriello, A. (2003) · Diabetes · doi:10.2337/diabetes.52.11.2795 · Cited by 772
Self-citation
Efficacy and safety of degludec versus glargine in type 2 diabetes.
Marso, S. P., McGuire, D. K., Zinman, B., Poulter, N. R., Emerson, S. S., Pieber, T. R., Pratley, R. E., Haahr, P.-M., Lange, M., Brown-Frandsen, K., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1615692 · Cited by 574

Show all 107 references

Research works printed but not linked: 4

Fleisher, 2017, Association of glycemic variability in type 1 diabetes with progression of microvascular outcomes in the Diabetes Control and Complications Trial, Diabetes Care, 40, 777, 10.2337/dc16-2426 · DOI
Fleisher, 2017, Association of glycemic variability in type 1 diabetes with progression of microvascular outcomes in the Diabetes Control and Complications Trial, Diabetes Care, 40, e164
Monnier, 2016, Comment on the FLAT-SUGAR Trial Investigators. Glucose variability in a 26-week randomized comparison of mealtime treatment with rapid-acting insulin versus GLP-1 agonist in participants with type 2 diabetes at high cardiovascular risk, Diabetes Care, 39, e186, 10.2337/dc16-1133 · DOI
2018, 8. Pharmacologic approaches to glycemic treatment: Standards of Medical Care in Diabetes—2018, Diabetes Care, 41, S73

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Xu, W., Sakal, C., Zhang, W., Chen, T., Wang, C., Zhao, Q., & Li, X. (2025) · medRxiv · doi:10.1101/2025.07.26.25332240 · Cited by 1
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Galeano, F., Tumminia, A., Oteri, V., Le Moli, R., Piticchio, T., Scilletta, S., Di Marco, M., Di Pino, A., & Frasca, F. (2026) · Endocrine · doi:10.1007/s12020-026-04693-6
“It also complicates both the achievement of recommended glycated hemoglobin (HbA1c) and time in range (TIR) targets [101, 102].”
Evaluating the safety and effectiveness of continuous glucose monitors for glycaemic control in intensive care.
Zhou, T. (2019) · UC Research Repository (University of Canterbury) · doi:10.26021/2871
Clinical impact of CGM use
Uduku, C. N., Reddy, M., & Oliver, N. S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816714-4.00007-7
CGMTSA: An R package for continuous glucose monitoring time series data analysisPreprint
Shao, J., Xu, T., & Zhou, K. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.06.174748
Ramadan et diabète
Monnier, L., Azrak, A. E., Rochd, D., & Colette, C. (2019) · Elsevier eBooks · doi:10.1016/b978-2-294-75889-8.00027-0
Self-citation
Macrophage activation in obese type 2 diabetes: an enhanced risk for COVID-19 and Acute Respiratory Distress Syndrome?Preprint
Moin, A. S. M., Sathyapalan, T., Diboun, I., Atkin, S. L., & Butler, A. E. (2020) · doi:10.21203/rs.3.rs-95244/v1
Variabilidad Glucémica como parámetro de control metabólico en pacientes con Diabetes tipo 1
Villalobos, J., Sandoval, G. H., Paz, J. J., Finol, M., & Colina, J. L. (2021) · Redalyc (Universidad Autónoma del Estado de México)
Impact of coronavirus disease 2019 on diabetic patients: An endocrinological perspective for better management
Agrawal, H., Das, N., Nathani, S., & Roy, P. (2021) · Journal of Reproductive Healthcare and Medicine · doi:10.25259/jrhm_29_2020
Acute and Long-term Effects of Saxagliptin on a Set of Cardiovascular Targets Measured at Fasting and Post-prandially in Obese Patients With Impaired Glucose Tolerance: a Randomized, Placebo-controlled, Double-blind StudyPreprint
Rezki, A., Cosson, E., Fysekidis, M., Chiheb, S., Vicaut, É., & Valensi, P. E. (2020) · Research Square · doi:10.21203/rs.3.rs-58025/v1
Beneficial effects of long-term liraglutide monotherapy on glycemic control and diabetic microangiopathies in a female Japanese diabetic patient with familial partial lipodystrophy 1
Iwanishi, M., Azuma, C., Tezuka, Y., Yamamoto, Y., Ito‐Kobayashi, J., Washiyama, M., Shimatsu, A., Mizuno, A., & Osafune, Y. (2021) · Diabetes Updates · doi:10.15761/du.1000150
Tempo de reação motora no diabetes mellitus tipo 2: revisão integrativa da literatura
Gervásio, F. M., Veloso, A. H. N., Brito, L. R. D. A., de Farias, A. B., & de Oliveira, F. B. (2021) · Research Society and Development · doi:10.33448/rsd-v10i10.19243
Glycemic Variability Within 1 Year Following Surgery for Stage II–III Colon Cancer
Mandolfo, N. R., Berger, A. M., Struwe, L. A., Hanna, K. M., Goldner, W. S., Klute, K. A., Langenfeld, S. J., & Hammer, M. J. (2021) · Biological Research For Nursing · doi:10.1177/10998004211035184
Study of Glycated Hemoglobin (HbA1C) biomarker among the Employees with type 2 Diabetes Mellitus in Relation to Various Other Modifiable Non Communicable Diseases Risk Factors at NSCBI Airport, Kolkata
Kundu, M. K., & Bhattacharya, M. (2021) · Indian Journal of Public Health Research & Development · doi:10.37506/ijphrd.v13i1.17318
Higher Long-term Visit-to-Visit Variability in Fasting Plasma Glucose Predicts New-Onset Heart Failure in the General PopulationPreprint
Wang, Y., Qi, W., Zhang, N., Tse, G., Li, G., Wu, S., & Liu, T. (2021) · Research Square · doi:10.21203/rs.3.rs-1183160/v1
Kardiovaskuläre Risiken in der 4.–6. Lebensdekade mit Diabetes mellitus Typ 1
Lee-Barkey, Y. H., Stratmann, B., & Tschöpe, D. (2022) · Der Diabetologe · doi:10.1007/s11428-021-00854-5
Adherence to Therapeutic Regimens in Diabetic Patients in Tertiary Care Hospitals
Mumtaz, A., Shah, M. I., Shaheen, G., Khan, Q. A., Ahmad, N., & Khan, A. M. (2022) · Pakistan Journal of Medical and Health Sciences · doi:10.53350/pjmhs221621033
Désordres glycémiques
(2019) · Elsevier eBooks · doi:10.1016/b978-2-294-75889-8.00004-x · Cited by 1
Dapagliflozin as an Adjunct Therapy to Insulin in Patients with Type 1 Diabetes Mellitus: Efficacy and Safety of this Combination
JENDLE, J. H., Ampudia‐Blasco, F. J., Füchtenbusch, M., & Pozzilli, P. (2021) · touchREVIEWS in Endocrinology · doi:10.17925/ee.2021.1.1.12
Macrophage activation in obese type 2 diabetes: an enhanced risk for COVID-19 and Acute Respiratory Distress Syndrome?Preprint
Moin, A. S. M., Sathyapalan, T., Diboun, I., Atkin, S. L., & Butler, A. E. (2020) · doi:10.21203/rs.3.rs-95244/v2
Désordres glycémiques et complications diabétiques : physiopathologie
Monnier, L., & Colette, C. (2019) · Elsevier eBooks · doi:10.1016/b978-2-294-75889-8.00009-9
Self-citation
A lone spike in blood glucose can enhance the thrombo-inflammatory response in cortical vesselsPreprint
Shaked, I., Foo, C., Liu, R., Cui, Y., Ji, X., Broggini, T., Mächler, P., Sundd, P., Devor, A., Friedman, B., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.08.10.503527
Glukose- und HbA1c-Variabilität sowie Zeit im Zielbereich (TIR)
Prattichizzo, F., & Ceriello, A. (2022) · Die Diabetologie · doi:10.1007/s11428-022-00968-4
Self-citation
Efficience et précision du contrôle glycémique dans le diabète : symphonie inachevée ?
Monnier, L., Halimi, S., & Colette, C. (2022) · Médecine des Maladies Métaboliques · doi:10.1016/j.mmm.2022.11.005
Self-citation
A case of bilateral pulmonary suppuration with multiple cavities in a type 1 diabetic hemodialysis patient
Miki, K., & Saito, T. (2023) · Nihon Toseki Igakkai Zasshi · doi:10.4009/jsdt.56.109
A surgical nursing perspective analysis of glucose variability in BCLC stage B–C hepatocellular carcinoma patients with and without T2D within 1 year of hepatectomy: a retrospective cohort study from 2016 to 2020
Wang, L., Zhu, J.-S., Zhan, F.-D., Tian, F., & Zhao, L. (2023) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo-23-163
Sistemi di monitoraggio della variabilità glicemica: nuovi parametri per la valutazione del compenso metabolico nel diabete
Buffardi, I., Pisarro, M., & Conti, F. (2023) · L Endocrinologo · doi:10.1007/s40619-023-01290-x
Focus on a special tool for postprandial glucose control: Ultra rapid lispro
Zhou, L., Qu, D., & Zhao, X. (2023) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/tb-2023-0508
A multi-centre investigation of macrovascular and non-ocular microvascular complications in children and adolescents with diabetes mellitus in southern Ghana
Akpalu, J., Essuman, V. A., Amoaku, W. M. K., Abaidoo, B., Essuman, A., Hayfron-Benjamin, C. F., Barnes, N. A., Tagoe, N. N., Asare, G. A., Ndanu, T. A., et al. (2023) · Ghana Medical Journal · doi:10.4314/gmj.v57i2.2
Links Between Glucose and Lipoproteins
Jenkins, A. J. (2023) · Contemporary diabetes · doi:10.1007/978-3-031-26681-2_3
Low-carbohydrate diet in the treatment of type 2 diabetes mellitus (LoCaT): study protocol for a multicenter, randomized controlled trial
Xia, X., Xu, M., Gu, Y., Li, Y., Li, L., & Yin, J. (2023) · Trials · doi:10.1186/s13063-023-07427-5
Thyroid function test variability and cardiovascular morbidity in hyperthyroidism
Suonsyrjä, N., Laihia, I., Huhtala, H., Jaatinen, P., & Metso, S. (2023) · Clinical Endocrinology · doi:10.1111/cen.14948
Glycemic control and cardiovascular complications of type 2 diabetes mellitus
Друк, И. В., & Safronova, S. S. (2023) · Meditsinskiy sovet = Medical Council · doi:10.21518/ms2023-222 · Cited by 1
Real-time continuous glucose monitoring systems in patients with type 1 diabetes. Expert group report
Zozulińska‐Ziółkiewicz, D., Malecki, M. T., Czupryniak, L., Jarosz-Chobot, P. A., Klupa, T., Myśliwiec, M., Szadkowska, A., Szypowska, A., Gawrecki, A., Mianowska, B., et al. (2021) · Current Topics in Diabetes · doi:10.5114/ctd/146220
The Effect of Insulin Degludec Versus Insulin Glargine U100 on Glucose Metrics Recorded During Continuous Glucose Monitoring in People With Type 1 Diabetes and Recurrent Nocturnal Severe Hypoglycemia
Brøsen, J. M. B., Agesen, R. M., Alibegovic, A. C., Andersen, H. U., Beck‐Nielsen, H., Gustenhoff, P., Hansen, T. K., Hedetoft, C., Jensen, T. J., Juhl, C. B., et al. (2023) · Journal of Diabetes Science and Technology · doi:10.1177/19322968231197423

Authors: Ceriello, A., Monnier, L., & Owens, D.
Affiliations: Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (ES)
Université de Montpellier (FR)
Swansea University (GB)
Corresponding author: Ceriello, Antonio
ORCID: Ceriello, Antonio
Monnier, Louis
Owens, David
Venue: The Lancet Diabetes & Endocrinology
Publisher: Elsevier BV
Published: 2019-03
Volume: 7
Issue: 3
Pages: 221-230
ISSN: 2213-8587 (ISSN-L)
DOI: 10.1016/s2213-8587(18)30136-0
OpenAlex: W2886853964
Cited by: 588
References: 107
Citations by year: 2026: 58 · 2025: 71 · 2024: 78 · 2023: 81 · 2022: 81 · 2021: 96 · 2020: 87 · 2019: 36
FWCI: 8.42
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet Diabetes & Endocrinology (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
Keywords: glycemic variability, diabetes mellitus, glucose homeostasis, glycaemic excursions, hyperglycemia, hypoglycemia, diabetes complications, HbA1c, diabetes management, glycemic control
MeSH terms: Blood Glucose, Diabetes Mellitus, Glycated Hemoglobin, Humans, Hyperglycemia, Hypoglycemia, Hypoglycemic Agents, Blood Glucose Self-Monitoring, Monitoring, Ambulatory, Diabetes Complications

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Glycaemic variability in diabetes: clinical and therapeutic implications

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