6. Glycemic Targets: Standards of Medical Care in Diabetes—2022

American Diabetes Association Professional Practice Committee

doi:10.2337/dc22-s006

Cited by 1,403Diabetes Management and ResearchDiabetes Treatment and ManagementDiabetes Management and Education

6. Glycemic Targets: Standards of Medical Care in Diabetes—2022

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American Diabetes Association Professional Practice Committee·2022·Diabetes Care

DOI 10.2337/dc22-s006

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Abstract

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc22-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc22-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.

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The mean HbA1c, GMI, TIR, and TBR results (8.0%, 7.6%, 56%, and 1.0% at 6 months, respectively) demonstrate close adherence to established glycemic targets.
“Considering the older age of participants and comorbid conditions reported, the mean HbA1c, GMI, TIR, and TBR results (8.0%, 7.6%, 56%, and 1.0% at 6 months, respectively) demonstrate close adherence to established glycemic targets (23, 24, 38).”
From Observed Glycemic and Psychosocial Benefits in the Prospective Bigfoot Unity Real World Study: A 6-Month Analysis (2025) · cites this paper as [24]
The Recommendations (p. 5) establish glycemic targets, and a TBR of 1.0% is within the stated <4% target. But the cited paper gives a TIR target of >70% for many nonpregnant adults, well above the reported 56%, and describes an A1C goal of <8% as a possible less stringent goal for selected patients—not a general target met by an A1C of 8.0%. It does not set a numerical GMI target or report the citing study’s six-month results, so it does not support the assessment that all four results closely adhere to its targets. (LLM, conf=0.88)
Experimental — accuracy not yet measured
HbA1c measurement has limitations.
“As with any laboratory test, HbA1c measurement has limitations (2,52).”
From Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (2022) · cites this paper as [2]
The greatest absolute risk reduction in glucose control comes from improving very elevated glycemic levels, while a more modest reduction results from near normalization of plasma glucose levels.
“The greatest absolute risk reduction comes from improving very elevated glycemic levels, and a more modest reduction results from near normalization of plasma glucose levels (2,14).”
From Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (2022) · cites this paper as [2]
Glycemic management is primarily assessed with the HbA1c test, which was the measure used in trials demonstrating the benefits of glucose lowering.
“Glycemic management is primarily assessed with the HbA1c test, which was the measure used in trials demonstrating the bene fi ts of glucose lowering (2,52).”
From Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (2022) · cites this paper as [2]
Low and very low glucose events occurred at a low rate (mean of ∼1.3 and 0.2 events per person per week in the sixth month, respectively) and were in keeping with time below range meeting established standards.
“Low and very low glucose events occurred at a low rate (mean of ∼1.3 and 0.2 events per person per week in the sixth month, respectively) and were in keeping with time below range meeting established standards (23, 24, 38).”
From Observed Glycemic and Psychosocial Benefits in the Prospective Bigfoot Unity Real World Study: A 6-Month Analysis (2025) · cites this paper as [24]

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Authors: American Diabetes Association Professional Practice Committee
Corresponding author: American Diabetes Association Professional Practice Committee
Venue: Diabetes Care
Publisher: American Diabetes Association
Published: 2021-12-16
Volume: 45
Issue: Supplement_1
Pages: S83-S96
ISSN: 0149-5992 (ISSN-L)
DOI: 10.2337/dc22-s006
OpenAlex: W4200358162
Semantic Scholar: a2d5992c30a9e8b02214ffbd9d329cfbb3094b63
Cited by: 1,403
References: 135
Citations by year: 2026: 70 · 2025: 158 · 2024: 246 · 2023: 369 · 2022: 273 · 2021: 126 · 2020: 86 · 2019: 56 · 2018: 14 · 2017: 2 · 2015: 3
FWCI: 38.90
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.diabetesjournals.org/content/license (vor)
Locations: Diabetes Care (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Keywords: glycemic targets, diabetes management, glycemic control, clinical guidelines, quality of care
MeSH terms: Blood Glucose, Diabetes Mellitus, Endocrinology, Humans, Reference Standards, Societies, Medical, Standard of Care

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