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Estimation of total phenolic content, in–vitro antioxidant and anti–inflammatory activity of flowers of Moringa oleifera

Open access
Alhakmani, Fatma, Kumar, Sokindra, Khan, Shah Alam·2013·Asian Pacific Journal of Tropical Biomedicine

Abstract

OBJECTIVE: To evaluate and compare the antioxidant potential and anti-inflammatory activity of ethanolic extract of flowers of Moringa oleifera (M. oleifera) grown in Oman. METHODS: Flowers of M. oleifera were collected in the month of December 2012 and identified by a botanist. Alcoholic extract of the dry pulverized flowers of M. oleifera were obtained by cold maceration method. The ethanolic flower extract was subjected to preliminary phytochemical screening as the reported methods. Folin-Ciocalteu reagent was used to estimate total phenolic content. DPPH was used to determine in-vitro antioxidant activity and anti-inflammatory activity of flowers was investigated by protein denaturation method. RESULTS: Phytochemical analysis of extract showed presence of major classes of phytochemicals such as tannins, alkaloids, flavonoids, cardiac glycosides etc. M. oleifera flowers were found to contain 19.31 mg/g of gallic acid equivalent of total phenolics in dry extract but exhibited moderate antioxidant activity. The anti-inflammatory activity of plant extract was significant and comparable with the standard drug diclofenac sodium. CONCLUSIONS: The results of our study suggest that flowers of M. oleifera possess potent anti-inflammatory activity and are also a good source of natural antioxidants. Further study is needed to identify the chemical compounds responsible for their anti-inflammatory activity.

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Metadata

Authors
Alhakmani, F., Kumar, S., & Khan, S. A.
Venue
Asian Pacific Journal of Tropical Biomedicine
Publisher
Medknow
Published
2013-08
Volume
3
Issue
8
Pages
623-627
ISSN
2221-1691 (ISSN-L)
OpenAlex
W2104078753
Cited by
403
References
19
FWCI
17.95
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Estimation of total phenolic content, in–vitro antioxidant and anti–inflammatory activity of flowers of Moringa oleifera. https://app.cochat.ai/papers/10.1016/s2221-1691(13)60126-4
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Alhakmani, F., Kumar, S., & Khan, S. A. (2013). Estimation of total phenolic content, in–vitro antioxidant and anti–inflammatory activity of flowers of Moringa oleifera. Asian Pacific Journal of Tropical Biomedicine. https://doi.org/10.1016/s2221-1691(13)60126-4

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