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The Neutral Theory of Molecular Evolution
Abstract
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.
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Items 101–114 of 114
The origin of higher taxa: macroevolutionary processes, and the case of the mammals
Kemp, T. S. (2007) · Acta Zoologica · doi:10.1111/j.1463-6395.2007.00248.x · Cited by 49
Networks and Hierarchies: Approaching Complexity in Evolutionary Theory
Tëmkin, I., & Eldredge, N. (2015) · Interdisciplinary Evolution Research · doi:10.1007/978-3-319-15045-1_6 · Cited by 49
Determining the Effect of Natural Selection on Linked Neutral Divergence across Species
Phung, T. N., Huber, C. D., & Lohmueller, K. E. (2016) · PLOS Genetics · doi:10.1371/journal.pgen.1006199 · Cited by 45
On the networked architecture of genotype spaces and its critical effects on molecular evolution
Aguirre, J., Catalán, P., Cuesta, J. A., & Manrubia, S. (2018) · Open Biology · doi:10.1098/rsob.180069 · Cited by 44
Bomba, L., Nicolazzi, E. L., Milanesi, M., Negrini, R., Mancini, G., Biscarini, F., Stella, A., Valentini, A., & Ajmone-Marsan, P. (2015) · Genetics Selection Evolution · doi:10.1186/s12711-015-0113-9 · Cited by 42
Reconstruction of the colonization of southern Madagascar by introduced Rattus rattus
Hingston, M., Goodman, S. M., Ganzhorn, J. U., & Sommer, S. (2005) · Journal of Biogeography · doi:10.1111/j.1365-2699.2005.01311.x · Cited by 38
Hidden Concepts in the History and Philosophy of Origins-of-Life Studies: A Workshop Report
Mariscal, C., Barahona, A., Aubert-Kato, N., Aydinoglu, A. U., Bartlett, S., Cárdenas, M. L., Chandru, K., Cleland, C., Cocanougher, B. T., Comfort, N., et al. (2019) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-019-09580-x · Cited by 36
Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle
Zhao, Y., Zheng, Z., Zhang, Z., Xu, Y., Hillpot, E., Lin, Y. S., Zakusilo, F. T., Lu, J. Y., Ablaeva, J., Biashad, S. A., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-43623-2 · Cited by 34
Evaluation of Methods to Detect Shifts in Directional Selection at the Genome Scale
(2022) · doi:10.1093/molbev/msac247 · Cited by 30
Limits of neutral drift: lessons from the in vitro evolution of two ribozymes
Petrie, K. L., & Joyce, G. F. (2014) · Journal of Molecular Evolution · doi:10.1007/s00239-014-9642-z · Cited by 27
Cahill, A. E., Meglécz, E., & Chenuil, A. (2024) · Biological Reviews · doi:10.1111/brv.13034 · Cited by 26
Quasispecies-like behavior observed in catalytic RNA populations evolving in a test tube
Diaz Arenas, C., & Lehman, N. (2010) · BMC Evolutionary Biology · doi:10.1186/1471-2148-10-80 · Cited by 25
Genomic signatures of convergent shifts to plunge-diving behavior in birds
Eliason, C. M., Mellenthin, L. E., Hains, T., McCullough, J. M., Pirro, S., Andersen, M. J., & Hackett, S. J. (2023) · Communications Biology · doi:10.1038/s42003-023-05359-z · Cited by 10
Biologists abandon Popper at their peril
(2000) · doi:10.1002/(sici)1521-1878(200002)22:2
Metadata
- Authors
- Kimura, M.
- Venue
- Cambridge University Press eBooks
- Publisher
- Cambridge University Press
- Published
- 1983-10-27
- OpenAlex
- W2575306271
- Cited by
- 6,347
- References
- 0
- FWCI
- 14.01
- Type
- book
- Language
- en
- Open access
- closed
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