The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Modelling the population cost-effectiveness of current and evidence-based optimal treatment for anxiety disorders
Abstract
BACKGROUND: The present paper describes a component of a large population cost-effectiveness study that aimed to identify the averted burden and economic efficiency of current and optimal treatment for the major mental disorders. This paper reports on the findings for the anxiety disorders (panic disorder/agoraphobia, social phobia, generalized anxiety disorder, post-traumatic stress disorder and obsessive compulsive disorder). METHOD: Outcome was calculated as averted 'years lived with disability' (YLD), a population summary measure of disability burden. Costs were the direct health care costs in 1997-8 Australian dollars. The cost per YLD averted (efficiency) was calculated for those already in contact with the health system for a mental health problem (current care) and for a hypothetical optimal care package of evidence-based treatment for this same group. Data sources included the Australian National Survey of Mental Health and Well-being and published treatment effects and unit costs. RESULTS: Current coverage was around 40% for most disorders with the exception of social phobia at 21%. Receipt of interventions consistent with evidence-based care ranged from 32% of those in contact with services for social phobia to 64% for post-traumatic stress disorder. The cost of this care was estimated at dollar 400 million, resulting in a cost per YLD averted ranging from dollar 7761 for generalized anxiety disorder to dollar 34 389 for panic/agoraphobia. Under optimal care, costs remained similar but health gains were increased substantially, reducing the cost per YLD to < dollar 20 000 for all disorders. CONCLUSIONS: Evidence-based care for anxiety disorders would produce greater population health gain at a similar cost to that of current care, resulting in a substantial increase in the cost-effectiveness of treatment.
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“Although effective behavioral and pharmacological interventions exist, many people struggling with SAD experience ongoing symptoms following treatment (16, 167) or do not present for treatment (5) indicating room for innovation in SAD treatment strategies.”
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Cites
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The economic burden of anxiety disorders in the 1990s
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“Greenberg et al. (1999) similarly reported that more than half of the annual costs of anxiety disorders in the United States were attributable to non-psychiatric medical treatment costs, a situation they argued could be avoided with increased recognition, appropriate referral and effective…”
BackgroundInfluentialThe quality of care for depressive and anxiety disorders in the United States
Young, A. S., Klap, R., Sherbourne, C. D., & Wells, K. B. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.1.55 · Cited by 1,061
Quality of Life in Individuals With Anxiety Disorders
Mendlowicz, M. V., & Stein, M. B. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.669 · Cited by 955
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Willingness to Pay for a Quality-adjusted Life Year: In Search of a Standard
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Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection
Kroenke, K., Spitzer, R. L., Williams, J. B. W., Monahan, P. O., & Löwe, B. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-5-200703060-00004 · Cited by 4,741
“While antidepressants are certainly effective for all 4 anxiety disorders, evidence-based psychotherapies, such as cognitive–behavioral therapy, are equally or more effective, are considered first-line treatment in some (but not all) clinical guidelines, and should strongly be considered if initial treatment with medi…”
BackgroundKroenke, K., Spitzer, R. L., Williams, J. B. W., & Löwe, B. (2010) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2010.03.006 · Cited by 4,057
“The four most common anxiety disorders (excluding simple phobias which seldom present clinically) are generalized anxiety disorder, panic disorder, social anxiety disorder and posttraumatic stress disorder (PTSD) [128].”
BackgroundInfluentialA Systematic Review of the Prevalence of Schizophrenia
Saha, S., Chant, D., Welham, J., & McGrath, J. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020141 · Cited by 2,168
Stein, M. B., & Stein, D. J. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60488-2 · Cited by 1,137
The global burden of anxiety disorders in 2010
Baxter, A. J., Vos, T., Scott, K. M., Ferrari, A. J., & Whiteford, H. A. (2014) · Psychological Medicine · doi:10.1017/s0033291713003243 · Cited by 768
“This is relevant to policy makers in terms of reducing population burden as current treatments are shown to be more cost-effective for mild and moderate cases than for severe cases (Issakidis et al. 2004).”
Background
Metadata
- Authors
- ISSAKIDIS, C., SANDERSON, K., CORRY, J., ANDREWS, G., & LAPSLEY, H.
- Affiliations
- UNSW Sydney (AU)
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2004-01
- Volume
- 34
- Issue
- 1
- Pages
- 19-35
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2036167557
- Cited by
- 110
- References
- 37
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 3 · 2021: 10 · 2020: 1 · 2019: 3 · 2018: 5 · 2017: 1 · 2016: 5 · 2015: 3 · 2014: 8 · 2013: 4 · 2012: 9
- FWCI
- 26.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- eCite Digital Repository (University of Tasmania) (submittedVersion)
- Figshare (submittedVersion)
- UEA Digital Repository (University of East Anglia) (submittedVersion)
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- anxiety disorders, cost-effectiveness, evidence-based treatment, years lived with disability, disability burden, generalized anxiety disorder, panic disorder, agoraphobia, social anxiety disorder, post-traumatic stress disorder, obsessive-compulsive disorder, treatment costs
- MeSH terms
- Anxiety Disorders, Australia, Cost-Benefit Analysis, Humans, Mental Health Services, Monte Carlo Method, Anti-Anxiety Agents, Cognitive Behavioral Therapy, Health Care Costs, Models, Econometric, Cost of Illness, Quality-Adjusted Life Years, Evidence-Based Medicine
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