Emotional and behavioural antecedents of young adults who screen positive for non-affective psychosis: a 21-year birth cohort study
Abstract
Background Birth cohort studies have shown that individuals who develop non-affective psychoses display subtle deviations in behaviour during childhood and adolescence. We had the opportunity to examine the widely used Child Behavior Checklist (CBCL) and the Youth Self-Report (YSR) to explore the antecedents of non-affective psychosis. Method Based on a birth cohort of 3801 young adults, psychopathology was assessed at years 5 and 14 using the CBCL and/or the YSR. Screen-positive non-affective psychosis (SP-NAP) was assessed at year 21 by using the Composite International Diagnostic Interview (CIDI) or a self-report checklist. The association between childhood symptoms and SP-NAP was examined using logistic regression. Results Of the cohort, 60 subjects were classified as SP-NAP. In males, SP-NAP was associated with higher scores: (a) on year 5 CBCL 'Total', 'Aggression' and 'Social, Attention and Thought' scores; (b) on year 14 CBCL 'Social', 'Attention' and 'Delinquency' scores, and (c) YSR 'Total' and many YSR subscores. These associations were less clear for females. Hallucinations at year 14 were associated with SP-NAP for both sexes. Boys with high 'Total' scores at both years 5 and 14 were at greatest risk of SP-NAP (a 5-fold risk), followed by boys and girls whose 'Social, Attention and Thought' scores either increased or remained high from years 5 to 14 (3- to 13-fold risk). Conclusions Individuals who screen positive for non-affective psychosis show increased psycho…
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The CBCL is widely used in pediatric psychiatry.
“The CBCL was developed by Achenbach et al. for the comprehensive assessment of children’s emotional and behavioral problems [61] and is widely used in pediatric psychiatry [62–65].”
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- Authors
- Welham, J., Scott, J., Williams, G., Najman, J., Bor, W., O'Callaghan, M., & McGrath, J.
- Affiliations
- Park Centre for Mental Health (AU)
- The University of Queensland (AU)
- Mater Children's Hospital (AU)
- Corresponding author
- McGrath, J.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2008-07-08
- Volume
- 39
- Issue
- 4
- Pages
- 625-634
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2111974164
- Cited by
- 288
- References
- 3
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 11 · 2023: 7 · 2022: 12 · 2021: 13 · 2020: 13 · 2019: 11 · 2018: 16 · 2017: 15 · 2016: 14 · 2015: 23 · 2014: 20 · 2013: 30 · 2012: 35
- FWCI
- 13.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- non-affective psychosis, schizophrenia, childhood psychopathology, adolescence, Child Behavior Checklist, Youth Self-Report, aggression, delinquency, hallucinations, sex differences, risk factors
- MeSH terms
- Adolescent, Affective Symptoms, Aggression, Attention Deficit Disorder with Hyperactivity, Marijuana Abuse, Child, Child Behavior Disorders, Child, Preschool, Female, Follow-Up Studies, Hallucinations, Humans, Male, Psychiatric Status Rating Scales, Psychometrics, Risk Factors, Schizophrenia, Schizotypal Personality Disorder, Social Adjustment, Statistics as Topic, Cohort Studies, Comorbidity, Early Diagnosis, Young Adult
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