Pathways from neurocognitive vulnerability to co-occurring internalizing and externalizing problems among women with and without attention-deficit/hyperactivity disorder followed prospectively for 16 years
Abstract
Using a sample of 228 females with and without childhood attention-deficit/hyperactivity disorder followed prospectively across 16 years, we measured childhood neurocognitive vulnerability via executive dysfunction using teacher-reported cognitive and learning problems. We then ascertained relations between dimensionally measured internalizing and externalizing psychopathology during adulthood and showed that childhood neurocognitive vulnerability reliably predicted such associated psychopathology. We identified six serial mediation pathways from childhood neurocognitive vulnerability to adult psychopathology through three early- and late-adolescent domains: individual (self-control and delay of gratification), peer (rejection/conflict and acceptance/friendship), and school (academic performance and school failure). The serial indirect effects occurred for the pathways from childhood neurocognitive vulnerability through early-adolescent academic performance, to late-adolescent school failure, to adult associated psychopathology, and from neurocognitive vulnerability through adolescent self-control and then the ability to delay gratification, to adult psychopathology. Furthermore, these indirect effects, plus two others, were moderated by parental distress during childhood and early adolescence, such that under conditions of high distress, the serial indirect effects were weaker than when parental distress was low. We discuss the potential importance of behavioral self-regulat…
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Pure ADHD is rare, and comorbidity is the rule in ADHD clinical samples.
“since 'pure' ADHD is rare, and comorbidity is the rule in ADHD clinical samples, with very few exceptions (Owens & Hinshaw, 2016;Yoshimasu et al., 2012)”
From Assessment of executive function in ADHD adolescents: contribution of performance tests and rating scales (2018) · cites this paper as Owens & Hinshaw, 2016
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“…age ¼ 14.1 years, range ¼ 11–17 years; see Hinshaw, Owens, Sami, & Fargeon, 2006) and 10 years later (Wave 3 [W3]; mean age ¼ 19.6 years, range ¼ 17–24; see Hinshaw et al., 2012) the girls were invited for follow-up assessments that involved two blinded, half-day lab visits for participants, and…”
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Hinshaw, S. P., Nguyen, P. T., O’Grady, S. M., & Rosenthal, E. A. (2022) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13480 · Cited by 424 · see citing works
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- Authors
- Owens, E. B., & Hinshaw, S. P.
- Affiliations
- University of California, Berkeley (US)
- Corresponding author
- Owens, Elizabeth B.
- Venue
- Development and Psychopathology
- Publisher
- Cambridge University Press (CUP)
- Published
- 2016-10-14
- Volume
- 28
- Issue
- 4pt1
- Pages
- 1013-1031
- ISSN
- 0954-5794 (ISSN-L)
- 1469-2198
- OpenAlex
- W2531324475
- Cited by
- 27
- References
- 16
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 4 · 2023: 6 · 2022: 1 · 2021: 5 · 2020: 1 · 2019: 3 · 2017: 4
- FWCI
- 2.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Development and Psychopathology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
- Keywords
- attention deficit hyperactivity disorder, executive dysfunction, internalizing problems, externalizing problems, women, girls, self-control, delay of gratification, peer rejection, peer acceptance, academic performance, school failure, parental distress, behavioral self-regulation, serial mediation
- MeSH terms
- Self-Control, Achievement, Adolescent, Adult, Attention, Attention Deficit Disorder with Hyperactivity, Female, Humans, Male, Parent-Child Relations, Parents, Peer Group, Prospective Studies, Stress, Psychological, Friends, Young Adult, Delay Discounting
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