INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia–CORRECTED VERSION
Abstract
Although several brief sensitive screening tools are available to detect cognitive dysfunction, few have been developed to quickly assess executive functioning (EF) per se. We designed a new brief tool to evaluate EF in neurodegenerative diseases. Patients with an established diagnosis of behavioral variant frontotemporal dementia (bvFTD; n = 22), Alzheimer disease (AD; n = 25), and controls (n = 26) were assessed with a cognitive screening test, the INECO Frontal Screening (IFS), and EF tests. Clinical Dementia Rating Scale (CDR) scores were obtained for all patients. Internal consistency of the IFS was very good (Cronbach's alpha = .80). IFS total (out of 30 points) was 27.4 (SD = 1.6) for controls, 15.6 (SD = 4.2) for bvFTD, and 20.1 (SD = 4.7) for AD. Using a cutoff of 25 points, sensitivity of the IFS was 96.2%, and specificity 91.5% in differentiating controls from patients with dementia. The IFS correlated significantly with the CDR and executive tasks. The IFS total discriminated controls from demented patients, and bvFTD from AD. IFS is a brief, sensitive, and specific tool for the detection of executive dysfunction associated with neurodegenerative diseases. The IFS may be helpful in the differential diagnosis of FTD and AD.
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Screening tools of executive functions such as the FAB and IFS can provide information on executive capacities in neurodegenerative and psychiatric conditions.
“Screening tools of executive functions such as The Frontal Assessment Battery (FAB) (Dubois et al. , 2000) and The Institute of Cognitive Neurology Frontal Screening (IFS) (Torralva et al. , 2009) can provide information on executive capacities in neurodegenerative and psychiatric conditions.”
From Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders (2020) · cites this paper as Torralva et al., 2009
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- Authors
- TORRALVA, T., ROCA, M., GLEICHGERRCHT, E., LÓPEZ, P., & MANES, F.
- Affiliations
- Favaloro University (AR)
- Instituto de Neurología Cognitiva (AR)
- Corresponding author
- TORRALVA, TERESA
- Venue
- Journal of the International Neuropsychological Society
- Publisher
- Cambridge University Press (CUP)
- Published
- 2009-07-28
- Volume
- 15
- Issue
- 5
- Pages
- 777-786
- ISSN
- 1355-6177 (ISSN-L)
- 1469-7661
- OpenAlex
- W2151627270
- Cited by
- 292
- References
- 1
- Citations by year
- 2026: 14 · 2025: 17 · 2024: 25 · 2023: 25 · 2022: 30 · 2021: 27 · 2020: 21 · 2019: 18 · 2018: 17 · 2017: 17 · 2016: 14 · 2015: 18 · 2014: 17 · 2013: 9 · 2012: 8
- FWCI
- 4.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the International Neuropsychological Society (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Keywords
- executive function, dementia screening, behavioral variant frontotemporal dementia, Alzheimer's disease, neurodegenerative diseases, differential diagnosis, sensitivity and specificity, Clinical Dementia Rating, frontal lobe dysfunction
- MeSH terms
- Aged, Aged, 80 and over, Alzheimer Disease, Cognition Disorders, Dementia, Diagnosis, Differential, Female, Humans, Male, Neuropsychological Tests, Problem Solving, Psychiatric Status Rating Scales, Sensitivity and Specificity
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