The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
A randomized, double-blind clinical trial on the efficacy of cortical direct current stimulation for the treatment of major depression
Open accessAbstract
Preliminary findings suggest that transcranial direct current stimulation (tDCS) can have antidepressant effects. We sought to test this further in a parallel-group, double-blind clinical trial with 40 patients with major depression, medication-free randomized into three groups of treatment: anodal tDCS of the left dorsolateral prefrontal cortex (active group - 'DLPFC'); anodal tDCS of the occipital cortex (active control group - 'occipital') and sham tDCS (placebo control group - 'sham'). tDCS was applied for 10 sessions during a 2-wk period. Mood was evaluated by a blinded rater using the Hamilton Depression Rating Scale (HDRS) and Beck Depression Inventory (BDI). The treatment was well tolerated with minimal side-effects that were distributed equally across all treatment groups. We found significantly larger reductions in depression scores after DLPFC tDCS [HDRS reduction of 40.4% (+/-25.8%)] compared to occipital [HDRS reduction of 21.3% (+/-12.9%)] and sham tDCS [HDRS reduction of 10.4% (+/-36.6%)]. The beneficial effects of tDCS in the DLPFC group persisted for 1 month after the end of treatment. Our findings support further investigation on the effects of this novel potential therapeutic approach - tDCS - for the treatment of major depression.
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Cites
Nitsche, M. A., & Paulus, W. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.t01-1-00633.x · Cited by 5,656
Self-citationDeep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
Frank, E. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810330075011 · Cited by 1,959 · cited 1×
“Clinical response was defined as a o50% decrease in HDRS score from baseline, and remission was defined as an HDRS score of f7 (Frank et al., 1991).”
Method(2003) · The Lancet · doi:10.1016/s0140-6736(03)12705-5 · Cited by 1,706
Magnetic Seizure Therapy Improves Mood in Refractory Major Depression
Kosel, M., Frick, C., Lisanby, S. H., Fisch, H.-U., & Schlaepfer, T. E. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300293 · Cited by 136
Cited by
Transcranial direct current stimulation: State of the art 2008
Nitsche, M. A., Cohen, L. G., Wassermann, E. M., Priori, A., Lang, N., Antal, A., Paulus, W., Hummel, F., Boggio, P. S., Fregni, F., et al. (2008) · Brain Stimulation · doi:10.1016/j.brs.2008.06.004 · Cited by 3,057
Self-citationPhysiological basis of transcranial direct current stimulation
Stagg, C. J., & Nitsche, M. A. (2011) · The Neuroscientist · doi:10.1177/1073858410386614 · Cited by 1,719
Self-citationBrunoni, A. R., Nitsche, M. A., Bolognini, N., Bikson, M., Wagner, T., Merabet, L., Edwards, D. J., Valero-Cabre, A., Rotenberg, A., Pascual-Leone, A., et al. (2012) · Brain stimulation · doi:10.1016/j.brs.2011.03.002 · Cited by 1,445
Self-citationA technical guide to tDCS, and related non-invasive brain stimulation tools
Woods, A. J., Antal, A., Bikson, M., Boggio, P. S., Brunoni, A. R., Celnik, P., Cohen, L. G., Fregni, F., Herrmann, C. S., Kappenman, E. S., et al. (2016) · Clinical Neurophysiology · doi:10.1016/j.clinph.2015.11.012 · Cited by 1,439
Self-citationTranscranial Alternating Current Stimulation Enhances Individual Alpha Activity in Human EEG
Zaehle, T., Rach, S., & Herrmann, C. S. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013766 · Cited by 803
Metadata
- Authors
- Boggio, P. S., Rigonatti, S. P., Ribeiro, R. B., Myczkowski, M. L., Nitsche, M. A., Pascual-Leone, A., & Fregni, F.
- Venue
- International Journal of Neuropsychopharmacology
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-03
- Volume
- 11
- Issue
- 2
- Pages
- 249-254
- ISSN
- 1461-1457 (ISSN-L)
- 1469-5111
- OpenAlex
- W2096707321
- Cited by
- 564
- References
- 5
- FWCI
- 11.51
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Boggio, P. S., Rigonatti, S. P., Ribeiro, R. B., Myczkowski, M. L., Nitsche, M. A., Pascual-Leone, A., & Fregni, F. (2008). A randomized, double-blind clinical trial on the efficacy of cortical direct current stimulation for the treatment of major depression. International Journal of Neuropsychopharmacology. https://doi.org/10.1017/s1461145707007833
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
