Association between gestational diabetes and perinatal depressive symptoms: Evidence from a Greek cohort study
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Aim The aim of the present study was to assess the association of gestational diabetes mellitus (GDM) with prenatal and postnatal depressive symptoms in a sample of pregnant women in Greece. BACKGROUND: Earlier research supports a relationship between depression and diabetes, but only a few studies have examined the relationship between GDM and perinatal depressive symptomatology. METHODS: A total of 117 women in their third trimester of pregnancy participated in the study. Demographic and obstetric history data were recorded during women's third trimester of pregnancy. Depressive symptoms were assessed with the validated Greek version of the Edinburg Postnatal Depression Scale (EPDS) at two time points: on the third trimester of pregnancy and on the first week postpartum. Findings Prevalence of GDM was 14.5%. Probable diagnosis of depression occurred for 12% of the sample during the antenatal assessment and 15.1% in the postpartum assessment. In the first week postpartum, women with GDM had significantly higher postpartum (but no antenatal) EPDS scores compared with the non-GDM cohort. In conclusion, GDM appears to be associated with depressive symptoms in the first week postpartum. Clinical implications and recommendations for future research are discussed, emphasizing the importance of closely monitoring women with GDM who seem more vulnerable to developing depressive symptomatology during the postnatal period.
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In Greece, GDM prevalence as assessed by Varela et al. was 14.5%.
“The GDM prevalence, as assessed by Varela et al., was 14.5% [127].”
From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [127]
Gestational diabetes mellitus has been linked to depressive symptoms in the postpartum period, but no association has been found with depression in the third pregnancy trimester.
“Gestational diabetes mellitus has been linked to depressive symptoms in the postpartum period (but no association has been found with depression in the third pregnancy trimester) [50]”
From Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature (2021) · cites this paper as [50]
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- Authors
- Varela, P., Spyropoulou, A. C., Kalogerakis, Z., Vousoura, E., Moraitou, M., & Zervas, I. M.
- Affiliations
- National and Kapodistrian University of Athens (GR)
- Alexander Technological Educational Institute of Thessaloniki (GR)
- Corresponding author
- Varela, Pinelopi
- Venue
- Primary Health Care Research & Development
- Publisher
- Cambridge University Press (CUP)
- Published
- 2017-06-05
- Volume
- 18
- Issue
- 5
- Pages
- 441-447
- ISSN
- 1463-4236 (ISSN-L)
- 1477-1128
- OpenAlex
- W2620626160
- Cited by
- 30
- References
- 42
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 2 · 2020: 4 · 2019: 4 · 2017: 1
- FWCI
- 2.31
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Primary Health Care Research & Development (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Keywords
- gestational diabetes mellitus, perinatal depression, postpartum depressive symptoms, antenatal depressive symptoms, pregnancy, maternal mental health, third trimester, Edinburgh Postnatal Depression Scale
- MeSH terms
- Adult, Female, Greece, Humans, Pregnancy, Pregnancy Trimester, Third, Risk Factors, Cohort Studies, Diabetes, Gestational, Risk Assessment, Perinatal Care, Depression, Postpartum, Pregnant People
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