The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Low-Cost Printing of Poly(dimethylsiloxane) Barriers To Define Microchannels in Paper
Open accessAbstract
This paper describes the use of a modified x,y-plotter to generate hydrophilic channels by printing a solution of hydrophobic polymer (pol(dimethylsiloxane; PDMS) dissolved in hexanes onto filter paper. The PDMS penetrates the depth of the paper and forms a hydrophobic wall that aqueous solutions cannot cross. The minimum size of printed features is approximately 1 mm; this resolution is adequate for the rapid prototyping of hand-held, visually read, diagnostic assays (and other microfluidic systems) based on paper. After curing the printed PDMS, the paper-based devices can be bent or folded to generate three-dimensional systems of channels. Capillary action pulls aqueous samples into the paper channels. Colorimetric assays for the presence of glucose and protein are demonstrated in the printed devices; spots of Bromothymol Blue distinguished samples with slightly basic pH (8.0) from samples with slightly acidic pH (6.5). The work also describes using printed devices that can be loaded using multipipets and printed flexible, foldable channels in paper over areas larger than 100 cm2.
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Cites
Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane)
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Self-citationPatterned Paper as a Platform for Inexpensive, Low‐Volume, Portable Bioassays
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Self-citationSolvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices
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Self-citationMicrofluidic diagnostic technologies for global public health
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Microfluidic devices fabricated in Poly(dimethylsiloxane) for biological studies
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Self-citationMicrofluidic platforms for lab-on-a-chip applications
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Self-citationEnsuring quality and access for malaria diagnosis: how can it be achieved?
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An Integrated Approach to a Portable and Low‐Cost Immunoassay for Resource‐Poor Settings
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Self-citationSolving the “World-to-Chip” Interface Problem with a Microfluidic Matrix
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Parallel Picoliter RT-PCR Assays Using Microfluidics
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Quantitative Evaluation of Urinalysis Test Strips
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Development of a rapid, simple dipstick dye immunoassay for schistosomiasis diagnosis
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Cited by
Flexographically Printed Fluidic Structures in Paper
Olkkonen, J., Lehtinen, K., & Erho, T. (2010) · Analytical Chemistry · doi:10.1021/ac1027066 · Cited by 369
Metadata
- Authors
- Bruzewicz, D. A., Reches, M., & Whitesides, G. M.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-03-12
- Volume
- 80
- Issue
- 9
- Pages
- 3387-3392
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2172079391
- Cited by
- 616
- References
- 17
- FWCI
- 15.99
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
