Cited by 350Spectroscopy Techniques in Biomedical and Chemical ResearchLaser-Matter Interactions and ApplicationsSpectroscopy and Quantum Chemical Studies

Stimulated Raman Scattering: From Bulk to Nano

Open access
Prince, Richard C., Frontiera, Renee R., Potma, Eric O.·2017·Chemical Reviews

Abstract

Stimulated Raman scattering (SRS) describes a family of techniques first discovered and developed in the 1960s. Whereas the nascent history of the technique is parallel to that of laser light sources, recent advances have spurred a resurgence in its use and development that has spanned across scientific fields and spatial scales. SRS is a nonlinear technique that probes the same vibrational modes of molecules that are seen in spontaneous Raman scattering. While spontaneous Raman scattering is an incoherent technique, SRS is a coherent process, and this fact provides several advantages over conventional Raman techniques, among which are much stronger signals and the ability to time-resolve the vibrational motions. Technological improvements in pulse generation and detection strategies have allowed SRS to probe increasingly smaller volumes and shorter time scales. This has enabled SRS research to move from its original domain, of probing bulk media, to imaging biological tissues and single cells at the micro scale, and, ultimately, to characterizing samples with subdiffraction resolution at the nanoscale. In this Review, we give an overview of the history of the technique, outline its basic properties, and present historical and current uses at multiple length scales to underline the utility of SRS to the molecular sciences.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1021/acs.chemrev.6b00545

Cites

209 of 209 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 4

  1. [5]Ng WK Woodbury EJ Ruby Laser Operation in Near IR Proc. Inst. Radio Eng 1962 50 2367
  2. [68]Boyd RW Nonlinear Optics 2003 Burlington Academic Press
  3. [70]Potma EO Mukamel S Cheng J-X Xie XS Coherent Raman Scattering Microscopy 2013 Baton Rouge, LA CRC Press
  4. [199]Wang P Slipchenko MN Mitchell J Yang C Potma EO Xu X Cheng J-X Far-Field Imaging of Non-Fluorescent Species with Subdiffraction Resolution Nat. Photonics 2013 7 449 453 24436725 PMC3891596

Cited by

Sorted by citations

Authors
Prince, R. C., Frontiera, R. R., & Potma, E. O.
Affiliations
  • University of California, Irvine (US)
  • University of Minnesota (US)
Corresponding author
Potma, Eric O.
Venue
Chemical Reviews
Published
2016-12-14
Volume
117
Issue
7
Pages
5070-5094
ISSN
  • 0009-2665 (ISSN-L)
  • 1520-6890
OpenAlex
W2563293115
Cited by
350
References
209
Citations by year
2026: 44 · 2025: 52 · 2024: 49 · 2023: 41 · 2022: 38 · 2021: 31 · 2020: 31 · 2019: 31 · 2018: 24 · 2017: 9
FWCI
2.62
Type
journal article
Language
en
Open access
Locations
  • Chemical Reviews (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • Division of Chemistry (CHE-1414466, CHE-1552849)
  • National Center for Research Resources (P41-RR01192)
  • Division of Graduate Education (DGE-1144901)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
  • Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Laser-Matter Interactions and Applications
  • Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Spectroscopy and Quantum Chemical Studies
Keywords
stimulated Raman scattering, nonlinear optics, vibrational spectroscopy, coherent Raman scattering, sub-diffraction resolution, nanoscale imaging, single-cell imaging, tissue imaging, laser pulse generation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review