Chemically sensitive bioimaging with coherent Raman scattering
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The CARS signal from aliphatic C-H2 bonds is specifically enriched in the lipid fraction, in particular in lipid droplets (LDs).
“In the context of lipid analysis, aliphatic C-H2 bonds can be probed, which are specifically enriched in the lipid fraction, in particular in LDs.”
From Label-free in vivo analysis of intracellular lipid droplets in the oleaginous microalga Monoraphidium neglectum by coherent Raman scattering microscopy (2016) · cites this paper as [17]
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Freudiger, C. W., Roeffaers, M. B. J., Zhang, X., Saar, B. G., Min, W., & Xie, X. S. (2011) · The Journal of Physical Chemistry B · doi:10.1021/jp1113834 · Cited by 40 · see citing works
Lee, Y. J., Vega, S. L., Patel, P. J., et al. (2013) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2013.0472 · Cited by 39 · see citing works
Rinia, H. A., Bonn, M., Vartiainen∥, E. M., Schaffer, C. B., & Mueller, M. (2006) · Journal of Biomedical Optics · doi:10.1117/1.2355671 · Cited by 33 · see citing works
The Impact of Array Detectors on Raman Spectroscopy
Denson, S. C., Pommier, C. J. S., & Denton, M. B. (2007) · Journal of Chemical Education · doi:10.1021/ed084p67 · Cited by 30 · see citing works
Mouras, R., Bagnaninchi, P., Downes, A. R., et al. (2012) · Journal of Biomedical Optics · doi:10.1117/1.jbo.17.11.116011 · Cited by 30 · see citing works
Balanced-detection Raman-induced Kerr-effect spectroscopy
Kumar, V., Casella, M., Molotokaite, E., Gatti, D., Kukura, P., Manzoni, C., Polli, D., Marangoni, M., & Cerullo, G. (2012) · Physical Review A · doi:10.1103/physreva.86.053810 · Cited by 26 · see citing works
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Bachler, B. R., Fermann, M. E., & Ogilvie, J. P. (2012) · Optics Express · doi:10.1364/oe.20.000835 · Cited by 20 · see citing works
Benalcazar, W. A., Chowdary, P. D., Jiang, Z. L., et al. (2009) · IEEE Journal of Selected Topics in Quantum Electronics · doi:10.1109/jstqe.2009.2035537 · Cited by 20 · see citing works
Raman Endoscopy for Objective Diagnosis of Early Cancer in the Gastrointestinal System
Bergholt, M. S. (2013) · Journal of Gastrointestinal & Digestive System · doi:10.4172/2161-069x.s1-008 · Cited by 20 · see citing works
Background-Free Nonlinear Microspectroscopy with Vibrational Molecular Interferometry
Garbacik, E. T., Korterik, J. P., Otto, C., et al. (2011) · Physical Review Letters · doi:10.1103/physrevlett.107.253902 · Cited by 19 · see citing works
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Nonlinear interferometric vibrational imaging of biological tissue
Jiang, Z. L., Marks, D. L., Geddes, J. B., et al. (2008) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.763306 · Cited by 1 · see citing works
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Sorted by citations
Rapid single-particle chemical imaging of nanoplastics by SRS microscopy
Qian, N., Gao, X., Lang, X., Deng, H., Bratu, T. M., Chen, Q., Stapleton, P., Yan, B., & Min, W. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2300582121 · Cited by 467 · see citing works
Biological imaging of chemical bonds by stimulated Raman scattering microscopy
Hu, F., Shi, L., & Min, W. (2019) · Nature Methods · doi:10.1038/s41592-019-0538-0 · Cited by 392 · see citing works
Stimulated Raman Scattering: From Bulk to Nano
Prince, R. C., Frontiera, R. R., & Potma, E. O. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00545 · Cited by 350 · see citing works
High-Speed Chemical Imaging by Dense-Net Learning of Femtosecond Stimulated Raman Scattering
Zhang, J., Zhao, J., Lin, H., Tan, Y., & Cheng, J.-X. (2020) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.0c01598 · Cited by 54 · see citing works
Jaeger, D., Pilger, C., Hachmeister, H., Oberländer, E., Wördenweber, R., Wichmann, J., Mussgnug, J. H., Huser, T., & Kruse, O. (2016) · Scientific Reports · doi:10.1038/srep35340 · Cited by 47 · see citing works
- Authors
- Camp Jr, C. H., & Cicerone, M. T.
- Affiliations
- National Institute of Standards and Technology (US)
- Corresponding author
- Cicerone, Marcus T.
- ORCID
- Cicerone, Marcus T.
- Venue
- Nature Photonics
- Published
- 2015-04-29
- Volume
- 9
- Issue
- 5
- Pages
- 295-305
- ISSN
- 1749-4885 (ISSN-L)
- 1749-4893
- OpenAlex
- W2047290343
- Cited by
- 472
- References
- 124
- Citations by year
- 2026: 30 · 2025: 33 · 2024: 32 · 2023: 46 · 2022: 35 · 2021: 40 · 2020: 54 · 2019: 43 · 2018: 50 · 2017: 51 · 2016: 45 · 2015: 13
- FWCI
- 32.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Photonics (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
- Physical Sciences › Physics and Astronomy › Acoustics and Ultrasonics › Random lasers and scattering media
- Keywords
- coherent Raman scattering, Raman imaging, chemical imaging, spontaneous Raman spectroscopy, chemical fingerprinting, functional imaging, biomedical imaging
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