The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Shortwave Infrared in Vivo Imaging with Gold Nanoclusters
Open accessAbstract
The use of visible/NIR-emitting gold nanoclusters (Au NCs), previously proposed for in vivo imaging, has been limited to some extent by low quantum yields (QYs) and the limited penetration of visible light in tissue. Here we report short wavelength infrared (SWIR, λ = 1–2 μm) emitting Au NCs with a good photoluminescence QY for this wavelength range (0.6% to 3.8% for λ em = 1000 to 900 nm) and excellent stability under physiological conditions. We show that surface ligand chemistry is critical to achieving these properties. We demonstrate the potential of these SWIR-emitting Au NCs for in vivo imaging in mice. The Au NCs have a hydrodynamic diameter that is small (∼5 nm) enough that they exhibit a rapid renal clearance, and images taken in the SWIR region show better resolution of the blood vessels than in the NIR region.
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Cites
Hong, G., Zou, Y., Antaris, A. L., Diao, S., Wu, D., Cheng, K., Zhang, X., Chen, C., Liu, B., He, Y., et al. (2014) · Nature Communications · doi:10.1038/ncomms5206 · Cited by 563
Cited by
Carr, J. A., Franke, D., Caram, J. R., Perkinson, C. F., Saif, M., Askoxylakis, V., Datta, M., Fukumura, D., Jain, R. K., Bawendi, M. G., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1718917115 · Cited by 721
Self-citationNear-infrared luminescence high-contrast in vivo biomedical imaging
Chen, Y., Wang, S., & Zhang, F. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-022-00002-8 · Cited by 566
Self-citationIn vivo NIR-II fluorescence imaging for biology and medicine
Wang, F., Zhong, Y., Bruns, O., Liang, Y., & Dai, H. (2024) · Nature Photonics · doi:10.1038/s41566-024-01391-5 · Cited by 564
Self-citationAnti-quenching NIR-II molecular fluorophores for in vivo high-contrast imaging and pH sensing
Wang, S., Fan, Y., Li, D., Sun, C., Lei, Z., Lu, L., Wang, T., & Zhang, F. (2019) · Nature Communications · doi:10.1038/s41467-019-09043-x · Cited by 510
Near-infrared II fluorescence imaging
Schmidt, E. L., Ou, Z., Ximendes, E., Cui, H., Keck, C. H. C., Jaque, D., & Hong, G. (2024) · Nature Reviews Methods Primers · doi:10.1038/s43586-024-00301-x · Cited by 331
Metadata
- Authors
- Chen, Y., Montana, D. M., Wei, H., Cordero, J. M., Schneider, M., Le Guével, X., Chen, O., Bruns, O. T., & Bawendi, M. G.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-09-27
- Volume
- 17
- Issue
- 10
- Pages
- 6330-6334
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2756603496
- Cited by
- 184
- References
- 1
- FWCI
- 8.13
- Type
- journal article
- Language
- en
- Open access
- green
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- Chen, Y., Montana, D. M., Wei, H., Cordero, J. M., Schneider, M., Le Guével, X., Chen, O., Bruns, O. T., & Bawendi, M. G. (2017). Shortwave Infrared in Vivo Imaging with Gold Nanoclusters. Nano Letters. https://doi.org/10.1021/acs.nanolett.7b03070
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