The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Second Near-Infrared Conjugated Polymer Nanoparticles for Photoacoustic Imaging and Photothermal Therapy
Abstract
Photothermal conversion in the second near-infrared (NIR-II) window allows deeper penetration and higher exposure to lasers, but examples of NIR-II photothermal agents are mainly formulated by inorganic compounds. In view of the underlying influence of inorganic materials, a novel NIR-II photothermal nanoagent based on a narrow band gap D-A conjugated polymer (TBDOPV-DT) with 2,2-bithiophene as the donor and thiophene-fused benzodifurandione-based oligo( p-phenylenevinylene) as the acceptor has been developed. More importantly, TBDOPV-DT nanoparticles (TBDOPV-DT NPs) are demonstrated to combine excellent photoacoustic imaging (PAI) and photothermal therapy (PTT) ability. TBDOPV-DT NPs exhibit dramatic photostability and heating reproducibility with a photothermal conversion efficiency of 50%. Especially, the NPs possess a remarkable PTT effect toward cancer cells in vitro and can eliminate tumor cells completely in vivo under 1064 nm laser irradiation, while no appreciable side effects have been observed. This study achieves PAI-guided cancer therapy and sheds light on the future of using organic polymer NPs for the NIR-II PTT of cancer.
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Nanocarriers as an emerging platform for cancer therapy
Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710
Photoacoustic tomography: In vivo imaging from organelles to organs
Wang, L. V., & Hu, S. (2012) · Science · doi:10.1126/science.1216210 · Cited by 4,331
Second window for in vivo imaging
Smith, A. M., Mancini, M. C., & Nie, S. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.326 · Cited by 2,848
Using Graphene Oxide High Near‐Infrared Absorbance for Photothermal Treatment of Alzheimer's Disease
Li, M., Yang, X., Ren, J., Qu, K., & Qu, X. (2012) · Advanced Materials · doi:10.1002/adma.201104864 · Cited by 535
Cited by
Second near-infrared photothermal materials for combinational nanotheranostics
Xu, C., & Pu, K. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00664e · Cited by 941
Gold Nanoparticles for Photothermal Cancer Therapy
Vines, J. B., Yoon, J.-H., Ryu, N.-E., Lim, D.-J., & Park, H. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00167 · Cited by 906
Design of superior phototheranostic agents guided by Jablonski diagrams
Feng, G., Zhang, G.-Q., & Ding, D. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00671h · Cited by 783
Design and Applications of Photoresponsive Hydrogels
Li, L., Scheiger, J. M., & Levkin, P. A. (2019) · Advanced Materials · doi:10.1002/adma.201807333 · Cited by 733
Guo, B., Sheng, Z., Hu, D., Liu, C., Zheng, H., & Liu, B. (2018) · Advanced Materials · doi:10.1002/adma.201802591 · Cited by 431
Metadata
- Authors
- Sun, T., Dou, J.-H., Liu, S., Wang, X., Zheng, X., Wang, Y., Pei, J., & Xie, Z.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2018-02-09
- Volume
- 10
- Issue
- 9
- Pages
- 7919-7926
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2791853162
- Cited by
- 220
- References
- 5
- FWCI
- 13.12
- Type
- journal article
- Language
- en
- Open access
- closed
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