The DOI matches its Crossref record; 106 of the 106 references it cites were found in a registry or an index.
Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It
Open accessAbstract
Gram-negative bacteria are intrinsically resistant to many antibiotics. Species that have acquired multidrug resistance and cause infections that are effectively untreatable present a serious threat to public health. The problem is broadly recognized and tackled at both the fundamental and applied levels. This paper summarizes current advances in understanding the molecular bases of the low permeability barrier of Gram-negative pathogens, which is the major obstacle in discovery and development of antibiotics effective against such pathogens. Gaps in knowledge and specific strategies to break this barrier and to achieve potent activities against difficult Gram-negative bacteria are also discussed.
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Cites
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Molecular Basis of Bacterial Outer Membrane Permeability Revisited
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Munoz-Price, L. S., Poirel, L., Bonomo, R. A., Schwaber, M. J., Daikos, G. L., Cormican, M., Cornaglia, G., Garau, J., Gniadkowski, M., Hayden, M. K., et al. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70190-7 · Cited by 1,627
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Cited by
Antibiotic resistance and persistence—implications for human health and treatment perspectives
Huemer, M., Mairpady Shambat, S., Brugger, S. D., & Zinkernagel, A. S. (2020) · The EMBO Reports · doi:10.15252/embr.202051034 · Cited by 850
Physical properties of the bacterial outer membrane
Sun, J., Rutherford, S. T., Silhavy, T. J., & Huang, K. C. (2022) · Nature Reviews Microbiology · doi:10.1038/s41579-021-00638-0 · Cited by 404
Metadata
- Authors
- Zgurskaya, H. I., López, C. A., & Gnanakaran, S.
- Venue
- ACS Infectious Diseases
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-09-25
- Volume
- 1
- Issue
- 11
- Pages
- 512-522
- ISSN
- 2373-8227 (ISSN-L)
- OpenAlex
- W2212629349
- Cited by
- 580
- References
- 106
- FWCI
- 13.77
- Type
- journal article
- Language
- en
- Open access
- green
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- Zgurskaya, H. I., López, C. A., & Gnanakaran, S. (2015). Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It. ACS Infectious Diseases. https://doi.org/10.1021/acsinfecdis.5b00097
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
