The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Nanosizing a Metal–Organic Framework Enzyme Carrier for Accelerating Nerve Agent Hydrolysis
Open accessAbstract
We report the synthesis and characterization of a water-stable zirconium metal-organic framework (MOF), NU-1003, featuring the largest mesoporous aperture known for a zirconium MOF. This material has been used to immobilize the nerve agent hydrolyzing enzyme, organophosphorus acid anhydrolase (OPAA). The catalytic efficiency of immobilized OPAA in nanosized NU-1003 is significantly increased compared to that of OPAA immobilized in microsized NU-1003 and even exceeds that of the free OPAA enzyme. This paper highlights a method for rapid and highly efficient hydrolysis of nerve agents using nanosized enzyme carriers.
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Cited by
Metal–Organic Framework-Based Hierarchically Porous Materials: Synthesis and Applications
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Ligand Rigidification for Enhancing the Stability of Metal–Organic Frameworks
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Metadata
- Authors
- Li, P., Moon, S.-Y., Guelta, M. A., Lin, L., Gómez-Gualdrón, D. A., Snurr, R. Q., Harvey, S. P., Hupp, J. T., & Farha, O. K.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-10-05
- Volume
- 10
- Issue
- 10
- Pages
- 9174-9182
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2528639231
- Cited by
- 266
- References
- 58
- FWCI
- 11.44
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Li, P., Moon, S.-Y., Guelta, M. A., Lin, L., Gómez-Gualdrón, D. A., Snurr, R. Q., Harvey, S. P., Hupp, J. T., & Farha, O. K. (2016). Nanosizing a Metal–Organic Framework Enzyme Carrier for Accelerating Nerve Agent Hydrolysis. ACS Nano. https://doi.org/10.1021/acsnano.6b04996
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