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Cited by 334

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Rationally Modulate the Oxidase-like Activity of Nanoceria for Self-Regulated Bioassays

Cheng, Hanjun, Lin, Shichao, Muhammad, Faheem, Lin, Ying-Wu, Wei, Hui·2016·ACS Sensors

Abstract

One of the current challenges in nanozyme-based technology is to rationally control the enzyme mimicking activities with suitable modulation strategies to mimic the complexity and functions of natural systems. In this regard, nanoceria has recently emerged as a promising nanozyme because of its unique enzyme mimicking properties. Herein, we demonstrated that the oxidase-like catalytic activity of nanoceria was rationally modulated in situ via proton-producing/consuming enzyme-catalyzed bioreactions, which formed the basis of self-regulated bioassays for determining the corresponding enzyme activity, as well as other important targets, such as nerve agents, drugs, and bioactive ions. More interestingly, the oxidase-like activity of nanoceria was cooperatively modulated with the aid of adenosine triphosphate, thus improving the analytical performance of such self-regulated bioassays. The current study not only demonstrated regulatory strategies to modulate the nanozymes’ activities, but also established a facile approach to designing self-regulated bioassays.

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Metadata

Authors
Cheng, H., Lin, S., Muhammad, F., Lin, Y.-W., & Wei, H.
Venue
ACS Sensors
Published
2016-11-01
Volume
1
Issue
11
Pages
1336-1343
ISSN
2379-3694 (ISSN-L)
OpenAlex
W2532290176
Cited by
334
References
3
FWCI
14.99
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Rationally Modulate the Oxidase-like Activity of Nanoceria for Self-Regulated Bioassays. https://app.cochat.ai/papers/10.1021/acssensors.6b00500
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Cheng, H., Lin, S., Muhammad, F., Lin, Y.-W., & Wei, H. (2016). Rationally Modulate the Oxidase-like Activity of Nanoceria for Self-Regulated Bioassays. ACS Sensors. https://doi.org/10.1021/acssensors.6b00500

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