The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Surface Coating of Graphene Quantum Dots Using Mussel-Inspired Polydopamine for Biomedical Optical Imaging
Abstract
Because of the superiority of GQDs (graphene quantum dots) in biomedical imaging, in terms of biocompatibility and toxicity of semiconductor quantum dots, GQDs bring new opportunities for the diagnosis and detection of diseases. In this study, we synthesized photoluminescent (PL) graphene quantum dots (GQDs) through a simple exfoliation and oxidation process, and then coated them with polydopamine (pDA) for enhanced stability in water and low toxicity in vivo. From the results, the GQDs coated with pDA showed an excellent stability of PL intensity. It showed that the PL intensity of noncoated GQDs in PBS solution rapidly decreased with time, resulting in a 45% reduction of the PL intensity for 14 days of incubation in PBS solution. After coating with polydopamine, PL intensities of polydopamine-coated GQDs was maintained more stably for 14 days compared with uncoated GQDs. We have observed the in vitro and in vivo biocompatibility of pDA-coated GQDs in nude mice. The overall observation revealed that pDA-coated GQDs could be used as a long-term optical imaging agent as well as a biocompatible drug carrier.
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Citations
Cites
Mussel-inspired surface chemistry for multifunctional coatings
Lee, H., Dellatore, S. M., Miller, W. M., & Messersmith, P. B. (2007) · Science · doi:10.1126/science.1147241 · Cited by 10,965
Attenuation of The In Vivo Toxicity of Biomaterials by Polydopamine Surface Modification
Hong, S., Kim, K. Y., Wook, H. J., Park, S. Y., Lee, K. D., Lee, D. Y., & Lee, H. (2011) · Nanomedicine · doi:10.2217/nnm.11.76 · Cited by 309
Self-citation
Cited by
Liu, Y., Ai, K., & Lu, L. (2014) · Chemical Reviews · doi:10.1021/cr400407a · Cited by 4,794
Glowing Graphene Quantum Dots and Carbon Dots: Properties, Syntheses, and Biological Applications
Zheng, X. T., Ananthanarayanan, A., Luo, K. Q., & Chen, P. (2015) · Small · doi:10.1002/smll.201402648 · Cited by 2,190
Polydopamine Surface Chemistry: A Decade of Discovery
Ryu, J. H., Messersmith, P. B., & Lee, H. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b19865 · Cited by 1,843
New Generation Cadmium-Free Quantum Dots for Biophotonics and Nanomedicine
Xu, G., Zeng, S., Zhang, B., Swihart, M. T., Yong, K.-T., & Prasad, P. N. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00290 · Cited by 587
The in vitro and in vivo toxicity of graphene quantum dots
Chong, Y., Ma, Y., Shen, H., Tu, X., Zhou, X., Xu, J., Dai, J., Fan, S., & Zhang, Z. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.03.021 · Cited by 530
Metadata
- Authors
- Nurunnabi, M., Khatun, Z., Nafiujjaman, M., Lee, D.-G., & Lee, Y.-K.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-08-06
- Volume
- 5
- Issue
- 16
- Pages
- 8246-8253
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2331535231
- Cited by
- 158
- References
- 2
- FWCI
- 7.70
- Type
- journal article
- Language
- en
- Open access
- closed
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