The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Bioinspired Synthesis and Characterization of Gadolinium-Labeled Magnetite Nanoparticles for Dual Contrast T1- and T2-Weighted Magnetic Resonance Imaging
Abstract
Gadolinium-labeled magnetite nanoparticles (GMNPs) were synthesized via a bioinspired manner to use as dual contrast agents for T1- and T2-weighted magnetic resonance imaging. A mussel-derived adhesive moiety, 3,4-dihydroxy-l-phenylalanine (DOPA), was utilized as a robust anchor to form a mixed layer of poly(ethylene glycol) (PEG) chains and dopamine molecules on the surface of iron oxide nanoparticles. Gadolinium ions were subsequently complexed at the distal end of the dopamine molecules that were prefunctionalized with a chelating ligand for gadolinium. The resultant GMNPs exhibited high dispersion stability in aqueous solution. Crystal structure and superparamagnetic properties of magnetite nanocrystals were also maintained after the complexation of gadolinium. The potential of GMNPs as dual contrast agents for T1 and T2-weighted magnetic resonance imaging was demonstrated by conducting in vitro and in vivo imaging and relaxivity measurements.
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Cites
Mussel-inspired surface chemistry for multifunctional coatings
Lee, H., Dellatore, S. M., Miller, W. M., & Messersmith, P. B. (2007) · Science · doi:10.1126/science.1147241 · Cited by 10,965
Nanostructures in Biodiagnostics
Rosi, N. L., & Mirkin, C. A. (2005) · Chemical Reviews · doi:10.1021/cr030067f · Cited by 4,603
Ultra-large-scale syntheses of monodisperse nanocrystals
Park, J., An, K., Hwang, Y., Park, J.-G., Noh, H.-J., Kim, J.-Y., Park, J.-H., Hwang, N.-M., & Hyeon, T. (2004) · Nature Materials · doi:10.1038/nmat1251 · Cited by 4,076
Metals and the Integrity of a Biological Coating: The Cuticle of Mussel Byssus
Holten-Andersen, N., Mates, T. E., Toprak, M. S., Stucky, G. D., Zok, F. W., & Waite, J. H. (2009) · Langmuir · doi:10.1021/la8027012 · Cited by 216
Cited by
Bioinspired catecholic chemistry for surface modification
Ye, Q., Zhou, F., & Liu, W. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15026j · Cited by 1,177
The chemistry behind catechol-based adhesion
Saiz‐Poseu, J., Mancebo‐Aracil, J., Nador, F., Busqué, F., & Ruiz‐Molina, D. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201801063 · Cited by 850
Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents
Busquets, M. A., Estelrich, J., & Sánchez-Martín, M. J. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s76501 · Cited by 622
Versatile Types of Organic/Inorganic Nanohybrids: From Strategic Design to Biomedical Applications
Zhao, N., Yan, L., Zhao, X., Chen, X., Li, A., Zheng, D., Zhou, X., Dai, X., & Xu, F.-J. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00401 · Cited by 429
A Synergistically Enhanced T1–T2 Dual‐Modal Contrast Agent
Zhou, Z., Huang, D., Bao, J., Chen, Q., Liu, G., Chen, Z., Chen, X., & Gao, J. (2012) · Advanced Materials · doi:10.1002/adma.201203169 · Cited by 293
Magnetic Nanostructures: Rational Design and Fabrication Strategies toward Diverse Applications
Wang, S., Xu, J., Li, W., Sun, S., Gao, S., & Hou, Y. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00370 · Cited by 129
Metadata
- Authors
- Bae, K. H., Kim, Y. B., Lee, Y., Hwang, J., Park, H., & Park, T. G.
- Venue
- Bioconjugate Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-02-18
- Volume
- 21
- Issue
- 3
- Pages
- 505-512
- ISSN
- 1043-1802 (ISSN-L)
- 1520-4812
- OpenAlex
- W2066424617
- Cited by
- 193
- References
- 4
- FWCI
- 10.38
- Type
- journal article
- Language
- en
- Open access
- closed
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